Large-scale temporal gene expression mapping of central nervous system development - PubMed (original) (raw)

Figure 2

Temporal gene expression map of the developing spinal cord. Expression patterns are labeled according to gene name and general functional class. Densitometry data from ratiometric RT-PCR and PAGE for triplicate animals are shown for each time point. Darkest, maximal expression; white, undetectable expression. MAP2, microtubule-associated protein 2; GAP43, growth-associated protein 43; L1, neural cell adhesion molecule (NCAM); NFL, NFM, NFH, neurofilament light, medium, and heavy; neno, neuron-specific enolase; GFAP, glial fibrillary acidic protein; MOG, myelin-oligodendrocyte glycoprotein; GAD65, glutamate decarboxylase 65; GAD67, G67I80/86, and G67I86, glutamate decarboxylase 67 splice variants; GAT1, GABA transporter 1; ChAT, choline acetyltransferase; AChE, acetylcholinesterase; ODC, ornithine decarboxylase; TH, tyrosine hydroxylase; NOS, nitric oxide synthase; GR, GABA receptor; mGluR, metabotropic glutamate receptor; NMDA, NMDA receptor; nAChR, nicotinic acetylcholine receptor; mAChR, muscarinic acetylcholine receptor; 5HT, serotonin (5-hydroxytryptamine) receptor; NGF, nerve growth factor; NT3, neurotrophin 3; BDNF, brain-derived neurotrophic factor; CNTF, ciliary neurotrophic factor (CNTFR, receptor); trk, NGF receptor; MK2, midkine 2; PTN, pleiotrophin; GDNF, glial-derived neurotrophic factor; EGF and EGFR, epidermal growth factor and its receptor; bFGF, aFGF, basic and acidic fibroblast growth factor; PDGF and PDGFR, platelet-derived growth factor and its receptor; FGFR, fibroblast growth factor receptor; TGFR, transforming growth factor receptor; Ins, insulin; InsR, insulin receptor; IGF, insulin-like growth factor; IGFR, IGF receptor; CRAF, c-raf protooncogene; IP3R, inositol 1,4,5-trisphosphate receptor; H2AZ, H2A.Z histone protein; Brm, brahma; TCP, t-complex protein; SOD, superoxide dismutase; CCO1 and CCO2, cytochrome c oxidase, subunits 1 and 2.