An atlas of serpin conformations - PubMed (original) (raw)

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An atlas of serpin conformations

J Whisstock et al. Trends Biochem Sci. 1998 Feb.

Abstract

The serpins are a family of proteins that inhibit chymotrypsin-like serine proteinases, with an unusual mechanism involving a large conformational change known as the stressed-->relaxed (S-->R) transition. This article is a guide to the known serpin conformations and their biological significance.

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