Localized requirements for windbeutel and pipe reveal a dorsoventral prepattern within the follicular epithelium of the Drosophila ovary - PubMed (original) (raw)
Localized requirements for windbeutel and pipe reveal a dorsoventral prepattern within the follicular epithelium of the Drosophila ovary
L A Nilson et al. Cell. 1998.
Free article
Abstract
Establishment of dorsoventral polarity within the Drosophila embryo requires extraembryonic positional information generated during oogenesis. The genes windbeutel, pipe, and nudel are required within the somatic follicle cells of the ovary for production of this spatial cue. Using a novel follicle cell marker system, we have directly evaluated the effect of mutant follicle cell clones on the embryonic dorsoventral pattern. We find no spatially localized requirement for nudel activity. In contrast, windbeutel and pipe are required only within a restricted ventral region of the follicular epithelium. This ventral region can determine lateral embryonic cell fates nonautonomously, indicating that spatial information originating ventrally is subsequently refined, perhaps via diffusion, to yield the gradient of positional information that determines the embryonic dorsoventral pattern.
Similar articles
- Spatially restricted expression of pipe in the Drosophila egg chamber defines embryonic dorsal-ventral polarity.
Sen J, Goltz JS, Stevens L, Stein D. Sen J, et al. Cell. 1998 Nov 13;95(4):471-81. doi: 10.1016/s0092-8674(00)81615-3. Cell. 1998. PMID: 9827800 - Windbeutel is required for function and correct subcellular localization of the Drosophila patterning protein Pipe.
Sen J, Goltz JS, Konsolaki M, Schüpbach T, Stein D. Sen J, et al. Development. 2000 Dec;127(24):5541-50. doi: 10.1242/dev.127.24.5541. Development. 2000. PMID: 11076773 - Multiple signaling pathways establish both the individuation and the polarity of the oocyte follicle in Drosophila.
Morgan MM, Mahowald AP. Morgan MM, et al. Arch Insect Biochem Physiol. 1996;33(3-4):211-30. doi: 10.1002/(SICI)1520-6327(1996)33:3/4<211::AID-ARCH4>3.0.CO;2-V. Arch Insect Biochem Physiol. 1996. PMID: 8913032 Review. - [Determination of the dorso-ventral polarity of the Drosophila embryo].
Mohier E. Mohier E. Ann Genet. 1993;36(1):5-15. Ann Genet. 1993. PMID: 8503650 Review. French.
Cited by
- Finishing the egg.
Berg C, Sieber M, Sun J. Berg C, et al. Genetics. 2024 Jan 3;226(1):iyad183. doi: 10.1093/genetics/iyad183. Genetics. 2024. PMID: 38000906 - Egg Morphology of Two Neotropical Dragonflies: Micrathyria hesperis and Miathyria simplex (Odonata: Libellulidae).
Giraldin MM, Bernardy JV, de Azevedo Brito PV, De Marco Júnior P. Giraldin MM, et al. Neotrop Entomol. 2023 Dec;52(6):1109-1118. doi: 10.1007/s13744-023-01081-x. Epub 2023 Sep 14. Neotrop Entomol. 2023. PMID: 37707765 - Stochastic phenotypes in RAS-dependent developmental diseases.
Marmion RA, Simpkins AG, Barrett LA, Denberg DW, Zusman S, Schottenfeld-Roames J, Schüpbach T, Shvartsman SY. Marmion RA, et al. Curr Biol. 2023 Mar 13;33(5):807-816.e4. doi: 10.1016/j.cub.2023.01.008. Epub 2023 Jan 26. Curr Biol. 2023. PMID: 36706752 Free PMC article. - Maternal control of the Drosophila dorsal-ventral body axis.
Stein DS, Stevens LM. Stein DS, et al. Wiley Interdiscip Rev Dev Biol. 2014 Sep-Oct;3(5):301-30. doi: 10.1002/wdev.138. Epub 2014 May 29. Wiley Interdiscip Rev Dev Biol. 2014. PMID: 25124754 Free PMC article. Review. - Molecular mechanisms of EGF signaling-dependent regulation of pipe, a gene crucial for dorsoventral axis formation in Drosophila.
Technau M, Knispel M, Roth S. Technau M, et al. Dev Genes Evol. 2012 Mar;222(1):1-17. doi: 10.1007/s00427-011-0384-2. Epub 2011 Dec 24. Dev Genes Evol. 2012. PMID: 22198544 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases