Caspases: key mediators of apoptosis - PubMed (original) (raw)

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Caspases: key mediators of apoptosis

N A Thornberry. Chem Biol. 1998 May.

Abstract

Recent studies have established that members of the caspase protease family are essential components of a conserved cell death program. Insights into their biological roles, structure and mechanism are enabling investigators to begin to explore the therapeutic potential of caspase inhibition.

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