Structure of locust adipokinetic hormone, a neurohormone that regulates lipid utilisation during flight - PubMed (original) (raw)
. 1976 Sep 16;263(5574):207-11.
doi: 10.1038/263207a0.
- PMID: 958472
- DOI: 10.1038/263207a0
Structure of locust adipokinetic hormone, a neurohormone that regulates lipid utilisation during flight
J V Stone et al. Nature. 1976.
Abstract
Adipokinetic hormone, isolated from locust corpora cardiaca, has been identified as a blocked peptide: PCA-Leu-Asn-Phe-Thr-Pro-Asn-Trp-Gly-Thr-NH2. The detailed structure is based on mass spectrometric data, substantiated in part by dansyl-Edman and carboxypeptidase data on thermolytic fragments. This is the first peptide hormone from an insect neuroendocrine organ to be fully characterised.
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