Structure of locust adipokinetic hormone, a neurohormone that regulates lipid utilisation during flight - PubMed (original) (raw)

. 1976 Sep 16;263(5574):207-11.

doi: 10.1038/263207a0.

• PMID: 958472
• DOI: 10.1038/263207a0

Structure of locust adipokinetic hormone, a neurohormone that regulates lipid utilisation during flight

J V Stone et al. Nature. 1976.

Abstract

Adipokinetic hormone, isolated from locust corpora cardiaca, has been identified as a blocked peptide: PCA-Leu-Asn-Phe-Thr-Pro-Asn-Trp-Gly-Thr-NH2. The detailed structure is based on mass spectrometric data, substantiated in part by dansyl-Edman and carboxypeptidase data on thermolytic fragments. This is the first peptide hormone from an insect neuroendocrine organ to be fully characterised.

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