Human anterior intraparietal area subserves prehension: a combined lesion and functional MRI activation study - PubMed (original) (raw)
Human anterior intraparietal area subserves prehension: a combined lesion and functional MRI activation study
F Binkofski et al. Neurology. 1998 May.
Abstract
It has been shown in nonhuman primates that the posterior parietal cortex is involved in coordination of arm and eye movements in space, whereas the anterior intraparietal area in the anterior lateral bank of the intraparietal sulcus plays a crucial role in fine finger movements, such as grasping. In this study we show by optoelectronic movement recordings that patients with cortical lesions involving the anterior lateral bank of the intraparietal sulcus have selective deficits in the coordination of finger movements required for object grasping, whereas reaching is much less disturbed. Patients with parietal lesions sparing the cortex lining the anterior intraparietal sulcus showed intact grasping behavior. Complementary evidence was obtained from functional MRI in normal control subjects showing a specific activation of the anterior lateral bank of the intraparietal sulcus during grasping. In conclusion, this combined lesion and activation study suggests that the anterior lateral bank of the intraparietal sulcus, possibly including the human homologue of the anterior intraparietal area, mediates the processing of sensorimotor integration of precisely tuned finger movements in humans.
Similar articles
- Cortical topography of human anterior intraparietal cortex active during visually guided grasping.
Frey SH, Vinton D, Norlund R, Grafton ST. Frey SH, et al. Brain Res Cogn Brain Res. 2005 May;23(2-3):397-405. doi: 10.1016/j.cogbrainres.2004.11.010. Epub 2005 Jan 22. Brain Res Cogn Brain Res. 2005. PMID: 15820646 - Functional organization of human posterior parietal cortex: grasping- and reaching-related activations relative to topographically organized cortex.
Konen CS, Mruczek RE, Montoya JL, Kastner S. Konen CS, et al. J Neurophysiol. 2013 Jun;109(12):2897-908. doi: 10.1152/jn.00657.2012. Epub 2013 Mar 20. J Neurophysiol. 2013. PMID: 23515795 Free PMC article. - The functional organization of the intraparietal sulcus in humans and monkeys.
Grefkes C, Fink GR. Grefkes C, et al. J Anat. 2005 Jul;207(1):3-17. doi: 10.1111/j.1469-7580.2005.00426.x. J Anat. 2005. PMID: 16011542 Free PMC article. Review. - Vision for Prehension in the Medial Parietal Cortex.
Fattori P, Breveglieri R, Bosco A, Gamberini M, Galletti C. Fattori P, et al. Cereb Cortex. 2017 Feb 1;27(2):1149-1163. doi: 10.1093/cercor/bhv302. Cereb Cortex. 2017. PMID: 26656999 Review.
Cited by
- Orientation representation in human visual cortices: contributions of non-visual information and action-related process.
Threethipthikoon T, Li Z, Shigemasu H. Threethipthikoon T, et al. Front Psychol. 2023 Dec 1;14:1231109. doi: 10.3389/fpsyg.2023.1231109. eCollection 2023. Front Psychol. 2023. PMID: 38106392 Free PMC article. - A review of brain regions and associated post-concussion symptoms.
Danielli E, Simard N, DeMatteo CA, Kumbhare D, Ulmer S, Noseworthy MD. Danielli E, et al. Front Neurol. 2023 Aug 3;14:1136367. doi: 10.3389/fneur.2023.1136367. eCollection 2023. Front Neurol. 2023. PMID: 37602240 Free PMC article. Review. - Decoding and geometry of ten finger movements in human posterior parietal cortex and motor cortex.
Guan C, Aflalo T, Kadlec K, Gámez de Leon J, Rosario ER, Bari A, Pouratian N, Andersen RA. Guan C, et al. J Neural Eng. 2023 May 25;20(3):036020. doi: 10.1088/1741-2552/acd3b1. J Neural Eng. 2023. PMID: 37160127 Free PMC article. - Altered cortical thickness and structural covariance networks in upper limb amputees: A graph theoretical analysis.
Bao B, Sun Y, Lin J, Gao T, Shen J, Hu W, Zhu H, Zhu T, Li J, Wang Z, Wei H, Zheng X. Bao B, et al. CNS Neurosci Ther. 2023 Oct;29(10):2901-2911. doi: 10.1111/cns.14226. Epub 2023 Apr 30. CNS Neurosci Ther. 2023. PMID: 37122148 Free PMC article. - Structure of the Motor Descending Pathways Correlates with the Temporal Kinematics of Hand Movements.
Begliomini C, Ceccarini F, Dell'Acqua VP, Budisavljevic S, Castiello U. Begliomini C, et al. Biology (Basel). 2022 Oct 10;11(10):1482. doi: 10.3390/biology11101482. Biology (Basel). 2022. PMID: 36290386 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical