B-cell receptor regulation of peripheral B cells - PubMed (original) (raw)
Review
B-cell receptor regulation of peripheral B cells
I C MacLennan. Curr Opin Immunol. 1998 Apr.
Abstract
Recent studies indicate that immature B cells compete with recirculating B cells for survival signals. The signals, delivered through the B-cell receptor for antigen, induce immature cells to differentiate into recirculating cells and maintain the survival of recirculating cells. They do not induce proliferation or differentiation to antibody-producing cells.