Identifying proteins and post-translational modifications by mass spectrometry - PubMed (original) (raw)

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Identifying proteins and post-translational modifications by mass spectrometry

B Küster et al. Curr Opin Struct Biol. 1998 Jun.

Abstract

Major recent advances in hardware performance, sample-handling procedures and software algorithms now allow reliable and sensitive mass spectrometric identification of proteins. Mass spectrometry vastly outperforms traditional sequencing technologies and thereby greatly facilitates the elucidation of the functions of individual proteins as well as multiprotein complexes and larger protein assemblages.

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