Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase - PubMed (original) (raw)

Review

Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase

C Birchmeier et al. Trends Cell Biol. 1998 Oct.

Abstract

A number of developmental processes that involve cell migration, growth or morphogenesis depend on extracellular signals. A molecule that provides such signals, known as hepatocyte growth factor/scatter factor (HGF/SF), has attracted considerable interest in recent years because of its distinct structure, mechanism of activation and important roles throughout embryogenesis. This review discusses the main features of HGF/SF and its receptor, the product of the c-met protooncogene, and their role in embryogenesis.

PubMed Disclaimer

Similar articles

• Hepatocyte growth factor as mitogen, motogen and morphogen, and its roles in organ regeneration.
  Nakamura T. Nakamura T. Princess Takamatsu Symp. 1994;24:195-213. Princess Takamatsu Symp. 1994. PMID: 8983076 Review.
• Expression of the met-receptor and its ligand, HGF-SF during mouse embryogenesis.
  Sonnenberg E, Weidner KM, Birchmeier C. Sonnenberg E, et al. EXS. 1993;65:381-94. EXS. 1993. PMID: 8380744 Review.
• The hepatocyte growth factor/Met pathway in development, tumorigenesis, and B-cell differentiation.
  van der Voort R, Taher TE, Derksen PW, Spaargaren M, van der Neut R, Pals ST. van der Voort R, et al. Adv Cancer Res. 2000;79:39-90. doi: 10.1016/s0065-230x(00)79002-6. Adv Cancer Res. 2000. PMID: 10818677 Review.
• HGF/SF and its receptor c-MET play a minor role in the dissemination of human B-lymphoma cells in SCID mice.
  Weimar IS, Weijer K, van den Berk PC, Muller EJ, Miranda N, Bakker AQ, Heemskerk MH, Hekman A, de Gast GC, Gerritsen WR. Weimar IS, et al. Br J Cancer. 1999 Sep;81(1):43-53. doi: 10.1038/sj.bjc.6690649. Br J Cancer. 1999. PMID: 10487611 Free PMC article.
• Expression of the met receptor tyrosine kinase in muscle progenitor cells in somites and limbs is absent in Splotch mice.
  Yang XM, Vogan K, Gros P, Park M. Yang XM, et al. Development. 1996 Jul;122(7):2163-71. doi: 10.1242/dev.122.7.2163. Development. 1996. PMID: 8681797

Cited by

• Prognostic value of c-Met expression in oral squamous cell carcinoma.
  Freudlsperger C, Alexander D, Reinert S, Hoffmann J. Freudlsperger C, et al. Exp Ther Med. 2010 Jan;1(1):69-72. doi: 10.3892/etm_00000012. Epub 2010 Jan 1. Exp Ther Med. 2010. PMID: 23136595 Free PMC article.
• MET inhibition in lung cancer.
  Menis J, Giaj Levra M, Novello S. Menis J, et al. Transl Lung Cancer Res. 2013 Feb;2(1):23-39. doi: 10.3978/j.issn.2218-6751.2012.12.04. Transl Lung Cancer Res. 2013. PMID: 25806202 Free PMC article. Review.
• High concentrations of HGF inhibit skeletal muscle satellite cell proliferation in vitro by inducing expression of myostatin: a possible mechanism for reestablishing satellite cell quiescence in vivo.
  Yamada M, Tatsumi R, Yamanouchi K, Hosoyama T, Shiratsuchi S, Sato A, Mizunoya W, Ikeuchi Y, Furuse M, Allen RE. Yamada M, et al. Am J Physiol Cell Physiol. 2010 Mar;298(3):C465-76. doi: 10.1152/ajpcell.00449.2009. Epub 2009 Dec 9. Am J Physiol Cell Physiol. 2010. PMID: 20007454 Free PMC article.
• Hepatocyte growth factor suppresses acute renal inflammation by inhibition of endothelial E-selectin.
  Gong R, Rifai A, Dworkin LD. Gong R, et al. Kidney Int. 2006 Apr;69(7):1166-74. doi: 10.1038/sj.ki.5000246. Kidney Int. 2006. PMID: 16501492 Free PMC article.
• Plasminogen-mediated activation and release of hepatocyte growth factor from extracellular matrix.
  Matsuoka H, Sisson TH, Nishiuma T, Simon RH. Matsuoka H, et al. Am J Respir Cell Mol Biol. 2006 Dec;35(6):705-13. doi: 10.1165/rcmb.2006-0006OC. Epub 2006 Jul 13. Am J Respir Cell Mol Biol. 2006. PMID: 16840775 Free PMC article.

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Elsevier Science

• Other Literature Sources

  • The Lens - Patent Citations Database

• Miscellaneous

  • NCI CPTAC Assay Portal