The invasion potentials of human biliary tract carcinoma cell lines: correlation between invasiveness and morphologic characteristics - PubMed (original) (raw)

. 1998 Dec;13(6):1269-74.

doi: 10.3892/ijo.13.6.1269.

Affiliations

The invasion potentials of human biliary tract carcinoma cell lines: correlation between invasiveness and morphologic characteristics

N Koike et al. Int J Oncol. 1998 Dec.

Abstract

The abilities of 9 kinds of human biliary tract carcinoma cell lines to invade through basement membrane or type I collagen were examined using an in vitro invasion assay system. The correlations between invasiveness and morphologic characteristics of the carcinoma cells in 3 dimensional collagen gel were also examined. most of the biliary tract carcinoma cell lines kept the abilities of glandular differentiation and basement membrane formation of the original tumor. Their invasiveness, however, correlated with the degree of in vitro morphologic differentiation regardless of their original morphology.

PubMed Disclaimer

Publication types

MeSH terms

Substances

LinkOut - more resources