Correlation of cecal microflora of HLA-B27 transgenic rats with inflammatory bowel disease - PubMed (original) (raw)

Correlation of cecal microflora of HLA-B27 transgenic rats with inflammatory bowel disease

A B Onderdonk et al. Infect Immun. 1998 Dec.

Abstract

Transgenic rats with a high level of expression of the human major histocompatibility complex class I molecule HLA-B27 develop chronic inflammatory bowel disease (IBD) and arthritis. Assessment of the cecal microflora showed a rise in numbers of Escherichia coli and Enterococcus spp., corresponding to the presence and severity of IBD in these rats.

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