Fatal enterovirus 71 encephalomyelitis - PubMed (original) (raw)
Case Reports
Fatal enterovirus 71 encephalomyelitis
L C Lum et al. J Pediatr. 1998 Dec.
Abstract
During an outbreak of hand-foot-mouth disease caused by enterovirus 71 (EV-71) in 1997, 4 children presented with sudden cardiopulmonary collapse and minimal neurologic features. All children received cardiopulmonary resuscitation but died within a few hours of admission. Postmortem studies showed infection by EV-71 with extensive damage to the medulla and pons. We postulate an etiologic link between EV-71 and brainstem encephalomyelitis as the cause of pulmonary edema and death.
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