Toward a complete human genome sequence - PubMed (original) (raw)

. 1998 Nov;8(11):1097-108.

doi: 10.1101/gr.8.11.1097.

Affiliations

• PMID: 9847074
• DOI: 10.1101/gr.8.11.1097

Free article

Toward a complete human genome sequence

Sanger Center et al. Genome Res. 1998 Nov.

Free article

Abstract

We have begun a joint program as part of a coordinated international effort to determine a complete human genome sequence. Our strategy is to map large-insert bacterial clones and to sequence each clone by a random shotgun approach followed by directed finishing. As of September 1998, we have identified the map positions of bacterial clones covering approximately 860 Mb for sequencing and completed >98 Mb ( approximately 3.3%) of the human genome sequence. Our progress and sequencing data can be accessed via the World Wide Web (http://webace.sanger.ac.uk/HGP/ or http://genome.wustl.edu/gsc/).

PubMed Disclaimer

Similar articles

• Automated finishing with autofinish.
  Gordon D, Desmarais C, Green P. Gordon D, et al. Genome Res. 2001 Apr;11(4):614-25. doi: 10.1101/gr.171401. Genome Res. 2001. PMID: 11282977 Free PMC article.
• Parallel construction of orthologous sequence-ready clone contig maps in multiple species.
  Thomas JW, Prasad AB, Summers TJ, Lee-Lin SQ, Maduro VV, Idol JR, Ryan JF, Thomas PJ, McDowell JC, Green ED. Thomas JW, et al. Genome Res. 2002 Aug;12(8):1277-85. doi: 10.1101/gr.283202. Genome Res. 2002. PMID: 12176935 Free PMC article.
• WebWise: guide to the joint genome institute web site.
  Pruitt KD. Pruitt KD. Genome Res. 1998 Sep;8(9):864-9. doi: 10.1101/gr.8.9.864. Genome Res. 1998. PMID: 9750187 Review. No abstract available.
• [Finishing the euchromatic sequence of the human genome].
  Hattori M. Hattori M. Tanpakushitsu Kakusan Koso. 2005 Feb;50(2):162-8. Tanpakushitsu Kakusan Koso. 2005. PMID: 15704464 Review. Japanese. No abstract available.

Cited by

• Improving draft assemblies by iterative mapping and assembly of short reads to eliminate gaps.
  Tsai IJ, Otto TD, Berriman M. Tsai IJ, et al. Genome Biol. 2010;11(4):R41. doi: 10.1186/gb-2010-11-4-r41. Epub 2010 Apr 13. Genome Biol. 2010. PMID: 20388197 Free PMC article.
• Characterization of clustered MHC-linked olfactory receptor genes in human and mouse.
  Younger RM, Amadou C, Bethel G, Ehlers A, Lindahl KF, Forbes S, Horton R, Milne S, Mungall AJ, Trowsdale J, Volz A, Ziegler A, Beck S. Younger RM, et al. Genome Res. 2001 Apr;11(4):519-30. doi: 10.1101/gr.gr-1603r. Genome Res. 2001. PMID: 11282967 Free PMC article.
• Comparative genome mapping in the sequence-based era: early experience with human chromosome 7.
  Thomas JW, Summers TJ, Lee-Lin SQ, Maduro VV, Idol JR, Mastrian SD, Ryan JF, Jamison DC, Green ED. Thomas JW, et al. Genome Res. 2000 May;10(5):624-33. doi: 10.1101/gr.10.5.624. Genome Res. 2000. PMID: 10810084 Free PMC article. Review.
• Theories and applications for sequencing randomly selected clones.
  Wendl MC, Marra MA, Hillier LW, Chinwalla AT, Wilson RK, Waterston RH. Wendl MC, et al. Genome Res. 2001 Feb;11(2):274-80. doi: 10.1101/gr.gr-1339r. Genome Res. 2001. PMID: 11157790 Free PMC article.
• The pseudogenes of eukaryotic translation elongation factors (EEFs): Role in cancer and other human diseases.
  Cristiano L. Cristiano L. Genes Dis. 2021 Apr 16;9(4):941-958. doi: 10.1016/j.gendis.2021.03.009. eCollection 2022 Jul. Genes Dis. 2021. PMID: 35685457 Free PMC article. Review.

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • HighWire

• Other Literature Sources

  • The Lens - Patent Citations Database

• Molecular Biology Databases

  • BioCyc
  • GlyGen glycoinformatics resource
  • SILVA

• Research Materials

  • NCI CPTC Antibody Characterization Program

• Miscellaneous

  • NCI CPTAC Assay Portal