Complexity and specificity of polysomal poly(A+) RNA in mouse tissues - PubMed (original) (raw)
Complexity and specificity of polysomal poly(A+) RNA in mouse tissues
B D Young et al. Biochemistry. 1976.
Abstract
Base sequence complexities of polysomal poly(A+)RNA from mouse embryo, brain, and liver have been estimated by hybridization to homologous cDNA to be approximately 7 x 109, 1.5 x 1010, and 7 x109 daltons, respectively. By annealing each cDNA with a large excess of total mouse embryo DNA, the genes coding for the polysomal poly(A+) sequences were shown to be unique. Heterologous hybridization experiments showed that the high abundance class of poly(A+) sequences in one tissue is not identical with the high abundance class in other tissues. However, at least 55%, and possibly more, of the poly(A+) RNA in one tissue is present in the poly(A+) RNA of another tissue.
Similar articles
- Complexity of poly(A+) and poly(A-) polysomal RNA in mouse liver and cultured mouse fibroblasts.
Grady LJ, North AB, Campbell WP. Grady LJ, et al. Nucleic Acids Res. 1978 Mar;5(3):697-712. doi: 10.1093/nar/5.3.697. Nucleic Acids Res. 1978. PMID: 643615 Free PMC article. - Analysis of rabbit brain polysomal poly (A+) mRNA by DNA excess hybridization.
Heikkila JJ, Brown IR. Heikkila JJ, et al. Biochim Biophys Acta. 1977 Jan 3;474(1):141-53. doi: 10.1016/0005-2787(77)90221-0. Biochim Biophys Acta. 1977. PMID: 831808 - Complexity of nuclear and polysomal polyadenylated RNA in a pluripotent embryonal carcinoma cell line.
Jacquet M, Affara NA, Robert B, Jakob H, Jacob F, Gros F. Jacquet M, et al. Biochemistry. 1978 Jan 10;17(1):69-79. doi: 10.1021/bi00594a010. Biochemistry. 1978. PMID: 618547 - [High molecular weight transcript of the homologous to the LINE sequence in polysome poly(A)--RNA in the rat brain].
Akulichev AV, Ryskov AP. Akulichev AV, et al. Mol Biol (Mosk). 1990 May-Jun;24(3):678-84. Mol Biol (Mosk). 1990. PMID: 1698254 Russian. - Complex population of nonpolyadenylated messenger RNA in mouse brain.
Van Ness J, Maxwell IH, Hahn WE. Van Ness J, et al. Cell. 1979 Dec;18(4):1341-9. doi: 10.1016/0092-8674(79)90244-7. Cell. 1979. PMID: 519772
Cited by
- Changes in nuclear and polysomal polyadenylated RNA sequences during rat-liver regeneration.
Wilkes PR, Birnie GD, Paul J. Wilkes PR, et al. Nucleic Acids Res. 1979;6(6):2193-208. doi: 10.1093/nar/6.6.2193. Nucleic Acids Res. 1979. PMID: 461186 Free PMC article. - Complexity of poly(A+) and poly(A-) polysomal RNA in mouse liver and cultured mouse fibroblasts.
Grady LJ, North AB, Campbell WP. Grady LJ, et al. Nucleic Acids Res. 1978 Mar;5(3):697-712. doi: 10.1093/nar/5.3.697. Nucleic Acids Res. 1978. PMID: 643615 Free PMC article. - Frequency distribution of mRNA and pre-mRNA in growing and differentiated Friend cells.
Mauron A, Spohr G. Mauron A, et al. Nucleic Acids Res. 1978 Aug;5(8):3013-32. doi: 10.1093/nar/5.8.3013. Nucleic Acids Res. 1978. PMID: 278967 Free PMC article. - Direct demonstration of immunoglobulin kappa chain RNA in thymus T cells by in situ hybridization.
Storb U. Storb U. Proc Natl Acad Sci U S A. 1978 Jun;75(6):2905-8. doi: 10.1073/pnas.75.6.2905. Proc Natl Acad Sci U S A. 1978. PMID: 96443 Free PMC article. - Studies on the intracellular segregation of polyribosome-associated messenger ribonucleic acid species in the lactating guinea-pig mammary gland.
Craig RK, Boulton AP, Harrison OS, Parker D, Campbell PN. Craig RK, et al. Biochem J. 1979 Sep 1;181(3):737-56. doi: 10.1042/bj1810737. Biochem J. 1979. PMID: 518553 Free PMC article.