Prostate cancer in the African American: is this a different disease? - PubMed (original) (raw)
Affiliations
- PMID: 9858329
Review
Prostate cancer in the African American: is this a different disease?
I J Powell. Semin Urol Oncol. 1998 Nov.
Abstract
Age-adjusted mortality rates from prostate cancer between 1991 and 1995 are approximately two times worse among African-American men than Caucasian men. Age-specific mortality rates from prostate cancer are reported to be three times greater among African-American men compared with Caucasian men between the ages of 40 and 60 years. These statistics lead one to ask whether the difference in outcome is secondary to a more rapidly growing prostate cancer among African-American men compared with Caucasian men, or is it a result of delayed diagnosis among African-American men, which would account for there being more advanced prostate cancer at presentation? This report demonstrates many histological and biological differences that may account for clinical outcome differences.
Similar articles
- Prostate cancer and African-American men.
Powell IJ. Powell IJ. Oncology (Williston Park). 1997 May;11(5):599-605; discussion 606-15 passim. Oncology (Williston Park). 1997. PMID: 9159788 Review. - Pathology of premalignant lesions and carcinoma of the prostate in African-American men.
Sakr WA, Grignon DJ, Haas GP. Sakr WA, et al. Semin Urol Oncol. 1998 Nov;16(4):214-20. Semin Urol Oncol. 1998. PMID: 9858328 Review. - Association Between African American Race and Clinical Outcomes in Men Treated for Low-Risk Prostate Cancer With Active Surveillance.
Deka R, Courtney PT, Parsons JK, Nelson TJ, Nalawade V, Luterstein E, Cherry DR, Simpson DR, Mundt AJ, Murphy JD, D'Amico AV, Kane CJ, Martinez ME, Rose BS. Deka R, et al. JAMA. 2020 Nov 3;324(17):1747-1754. doi: 10.1001/jama.2020.17020. JAMA. 2020. PMID: 33141207 Free PMC article. - African-American Men with Gleason Score 3+3=6 Prostate Cancer Produce Less Prostate Specific Antigen than Caucasian Men: A Potential Impact on Active Surveillance.
Kryvenko ON, Balise R, Soodana Prakash N, Epstein JI. Kryvenko ON, et al. J Urol. 2016 Feb;195(2):301-6. doi: 10.1016/j.juro.2015.08.089. Epub 2015 Sep 2. J Urol. 2016. PMID: 26341575
Cited by
- A Rich Array of Prostate Cancer Molecular Biomarkers: Opportunities and Challenges.
Kohaar I, Petrovics G, Srivastava S. Kohaar I, et al. Int J Mol Sci. 2019 Apr 12;20(8):1813. doi: 10.3390/ijms20081813. Int J Mol Sci. 2019. PMID: 31013716 Free PMC article. Review. - Biomarkers for the detection and prognosis of prostate cancer.
Hernandez J, Canby-Hagino E, Thompson IM. Hernandez J, et al. Curr Urol Rep. 2005 May;6(3):171-6. doi: 10.1007/s11934-005-0004-7. Curr Urol Rep. 2005. PMID: 15869720 Review. - Black men have lower rates than white men of biochemical failure with primary androgen-deprivation therapy.
Sassani P, Blumberg JM, Cheetham TC, Niu F, Williams SG, Chien GW. Sassani P, et al. Perm J. 2011 Summer;15(3):4-8. doi: 10.7812/TPP/11-096. Perm J. 2011. PMID: 22058663 Free PMC article. - Expression differences between African American and Caucasian prostate cancer tissue reveals that stroma is the site of aggressive changes.
Kinseth MA, Jia Z, Rahmatpanah F, Sawyers A, Sutton M, Wang-Rodriguez J, Mercola D, McGuire KL. Kinseth MA, et al. Int J Cancer. 2014 Jan 1;134(1):81-91. doi: 10.1002/ijc.28326. Epub 2013 Jul 13. Int J Cancer. 2014. PMID: 23754304 Free PMC article. - Prostate cancer detection strategies.
Brand TC, Hernandez J, Canby-Hagino ED, Basler JW, Thompson IM. Brand TC, et al. Curr Urol Rep. 2006 May;7(3):181-5. doi: 10.1007/s11934-006-0019-8. Curr Urol Rep. 2006. PMID: 16630521 Review.
Publication types
MeSH terms
LinkOut - more resources
Medical