Control of immune pathology by regulatory T cells - PubMed (original) (raw)
Review
Control of immune pathology by regulatory T cells
D Mason et al. Curr Opin Immunol. 1998 Dec.
Abstract
There is now compelling evidence that immune responses for both foreign and self antigens are downregulated by T cells that are specialised for this function; these are known as regulatory T (T reg) cells. This review describes progress in the characterisation of the T reg cells that mediate both mucosal tolerance and tolerance to self antigens. The recent work on the antigen specificity, generation and mode of action of T reg cells is also reviewed.
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