The central Siberian origin for native American Y chromosomes - PubMed (original) (raw)

The central Siberian origin for native American Y chromosomes

F R Santos et al. Am J Hum Genet. 1999 Feb.

Abstract

Y chromosomal DNA polymorphisms were used to investigate Pleistocene male migrations to the American continent. In a worldwide sample of 306 men, we obtained 32 haplotypes constructed with the variation found in 30 distinct polymorphic sites. The major Y haplotype present in most Native Americans was traced back to recent ancestors common with Siberians, namely, the Kets and Altaians from the Yenissey River Basin and Altai Mountains, respectively. Going further back, the next common ancestor gave rise also to Caucasoid Y chromosomes, probably from the central Eurasian region. This study, therefore, suggests a predominantly central Siberian origin for Native American paternal lineages for those who could have migrated to the Americas during the Upper Pleistocene.

PubMed Disclaimer

Similar articles

• The dual origin and Siberian affinities of Native American Y chromosomes.
  Lell JT, Sukernik RI, Starikovskaya YB, Su B, Jin L, Schurr TG, Underhill PA, Wallace DC. Lell JT, et al. Am J Hum Genet. 2002 Jan;70(1):192-206. doi: 10.1086/338457. Epub 2001 Nov 30. Am J Hum Genet. 2002. PMID: 11731934 Free PMC article.
• Y chromosome polymorphisms in native American and Siberian populations: identification of native American Y chromosome haplotypes.
  Lell JT, Brown MD, Schurr TG, Sukernik RI, Starikovskaya YB, Torroni A, Moore LG, Troup GM, Wallace DC. Lell JT, et al. Hum Genet. 1997 Oct;100(5-6):536-43. doi: 10.1007/s004390050548. Hum Genet. 1997. PMID: 9341867
• High-resolution SNPs and microsatellite haplotypes point to a single, recent entry of Native American Y chromosomes into the Americas.
  Zegura SL, Karafet TM, Zhivotovsky LA, Hammer MF. Zegura SL, et al. Mol Biol Evol. 2004 Jan;21(1):164-75. doi: 10.1093/molbev/msh009. Epub 2003 Oct 31. Mol Biol Evol. 2004. PMID: 14595095
• Population genetics, history, and health patterns in native americans.
  Mulligan CJ, Hunley K, Cole S, Long JC. Mulligan CJ, et al. Annu Rev Genomics Hum Genet. 2004;5:295-315. doi: 10.1146/annurev.genom.5.061903.175920. Annu Rev Genomics Hum Genet. 2004. PMID: 15485351 Review.
• The late Pleistocene dispersal of modern humans in the Americas.
  Goebel T, Waters MR, O'Rourke DH. Goebel T, et al. Science. 2008 Mar 14;319(5869):1497-502. doi: 10.1126/science.1153569. Science. 2008. PMID: 18339930 Review.

Cited by

• North Asian population relationships in a global context.
  Kidd KK, Evsanaa B, Togtokh A, Brissenden JE, Roscoe JM, Dogan M, Neophytou PI, Gurkan C, Bulbul O, Cherni L, Speed WC, Murtha M, Kidd JR, Pakstis AJ. Kidd KK, et al. Sci Rep. 2022 May 4;12(1):7214. doi: 10.1038/s41598-022-10706-x. Sci Rep. 2022. PMID: 35508562 Free PMC article.
• Novel alleles gained during the Beringian isolation period.
  Niedbalski SD, Long JC. Niedbalski SD, et al. Sci Rep. 2022 Mar 11;12(1):4289. doi: 10.1038/s41598-022-08212-1. Sci Rep. 2022. PMID: 35277570 Free PMC article.
• Potential research ethics violations against an indigenous tribe in Ecuador: a mixed methods approach.
  Ortiz-Prado E, Simbaña-Rivera K, Gómez-Barreno L, Tamariz L, Lister A, Baca JC, Norris A, Adana-Diaz L. Ortiz-Prado E, et al. BMC Med Ethics. 2020 Oct 17;21(1):100. doi: 10.1186/s12910-020-00542-x. BMC Med Ethics. 2020. PMID: 33069227 Free PMC article.
• New native South American Y chromosome lineages.
  Jota MS, Lacerda DR, Sandoval JR, Vieira PP, Ohasi D, Santos-Júnior JE, Acosta O, Cuellar C, Revollo S, Paz-Y-Miño C, Fujita R, Vallejo GA, Schurr TG, Tarazona-Santos EM, Pena SDj, Ayub Q, Tyler-Smith C, Santos FR; Genographic Consortium. Jota MS, et al. J Hum Genet. 2016 Jul;61(7):593-603. doi: 10.1038/jhg.2016.26. Epub 2016 Mar 31. J Hum Genet. 2016. PMID: 27030145
• Toward a new history and geography of human genes informed by ancient DNA.
  Pickrell JK, Reich D. Pickrell JK, et al. Trends Genet. 2014 Sep;30(9):377-89. doi: 10.1016/j.tig.2014.07.007. Epub 2014 Aug 26. Trends Genet. 2014. PMID: 25168683 Free PMC article. Review.

References

1. 1. Hum Biol. 1992 Jun;64(3):381-402 - PubMed
2. 1. Nature. 1995 Nov 23;378(6555):379-80 - PubMed
3. 1. Nat Genet. 1995 Sep;11(1):15-6 - PubMed
4. 1. Am J Hum Genet. 1993 Sep;53(3):563-90 - PubMed
5. 1. Am J Hum Genet. 1995 Apr;56(4):951-62 - PubMed

Publication types

MeSH terms

LinkOut - more resources

• Full Text Sources

  • Elsevier Science
  • Europe PubMed Central
  • PubMed Central

• Research Materials

  • Coriell Cell Repositories