Dr.Shazia Murtaza | Formerly King Saaud Univeristy and King Khalid University Hospital, Riyadh, Saudi Arabia (original) (raw)
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Papers by Dr.Shazia Murtaza
The professional medical journal, Jul 10, 2018
over one year. Subjects & Methods: 30 pediatric cases urinary bladder urolithiasis were selected.... more over one year. Subjects & Methods: 30 pediatric cases urinary bladder urolithiasis were selected. Children of age few of ten years were selected. Any contamination form bladder stone was removed by washing them in distilled deionized water. Stones were dried for an overnight in an oven at temperature of 100 0 C. Dried stones were smashed into pieces. Biochemical analysis was performed by the FTIR spectroscopy (Nicolet Avatar 330 FTIR spectrophotometer). Results were analyzed on the software SPSS 22.0 (95% confidence interval). Results: Mean age was 4.83 years (SD 2.81 years). Of 30 children, 80% (n=24) were male and 20% (n=6) were female children. Male to female ratio of 4:1 was noted. 16.6% (n=5) were pure stone and 83.3% (n=25) were mixed stones. (P=0.0001). Biochemical analysis showed the calcium oxalate monohydrate (COM)-ammonium hydrogen urate (AHU) was the most common urinary bladder stone. Conclusions: The pediatric urolithiasis shows the most common type of urinary bladder stone was the calcium oxalate monohydrate-ammonium hydrogen urate.
Journal of Pharmaceutical Research International
Aim: To determine the correlation of HBA1c and serum cholesterol in diabetic patients. Methodolog... more Aim: To determine the correlation of HBA1c and serum cholesterol in diabetic patients. Methodology: This case control study was completed at the Biochemistry and Medicine Departments of Liaquat University Hospital Jamshoro from October 2015 to March 2016.Total number of study subject was 100 and they were divided into two groups. Group A (case group, n=50) comprises diagnosed T2DM subjects while group B (control group, n=50) consists of healthy normal subjects (HNS), healthy normal subjects with mean age 50±6.34 years. These subjects were assessed to find association of glycosylated hemoglobin with serum Cholesterol levels in Type-2 Diabetes mellitus patients. Those patients diagnosed asT2DM with age 30- 60years were included while those patients diagnosed as diabetic erectile dysfunction, diabetic nephropathy, diabetic renal failure, familial dyslipidemia, and hypercholesterolemia was excluded in this study. Blood specimens were collected from both groups aseptically then blood glu...
To analyze the biochemical composition and biochemical types of urinary bladder stones in childre... more To analyze the biochemical composition and biochemical types of urinary bladder stones in children. Study design and setting: Observational study,
Aim: To determine correlation of serum testosterone with low and high density lipoprotein in male... more Aim: To determine correlation of serum testosterone with low and high density lipoprotein in male type 2 Diabetics presenting at a tertiary care hospital of Sindh. Methodology: A cross sectional study, Department of Biochemistry and Department of Medicine, Liaquat University Hospital from January 2018 to February 2019. One hundred male type 2 diabetics (cases) and one hundred age matched male (control) were selected through non – probability purposive sampling. Male diagnosed cases of DM belonging to 4th to 6th decade of life was included. Blood samples were collected by venesection and sera were squeezed by centrifugation and stored at – 20 0C in refrigerators. Testosterone was estimated by the ELISA (competitive immuno- assay) assay method and blood lipids - cholesterol, triglycerides (TAGs), LDLc and HDLc by colorimetric method. Pearson`s correlation was generated on Statistical software SPSS 21.0 version (IBM, Incorp, USA) for correlation of serum testosterone with lipids fract...
Journal of Pharmaceutical Research International
Aim: To determine the serum testosterone levels in the type 2 diabetes mellitus and its correlati... more Aim: To determine the serum testosterone levels in the type 2 diabetes mellitus and its correlation with biochemical parameters of glycemic and lipid metabolism. Methodology: A cross sectional study was conducted at Department of Biochemistry and Department of Medicine, A cross sectional study was conducted at the Department of Biochemistry, Diabetic outpatient department and Department of Medicine, Liaquat University Hospital. Male type 2 diabetics (n=100) and age matched male (n=100) were included as cases and control for study purpose. Diagnosed cases of type 2 DM, male gender and 40 – 60 years of age were included in the study protocol. Physical examination of male type 2 diabetics was performed by a consultant physician. Sera were separated from blood and stored in refrigerators at – 200C. Blood glucose, A1C, and blood lipids (cholesterol, triglycerides, LDLc and HDLc) were detected by standard laboratory methods. Serum testosterone was measured by ELISA (competitive immuno- as...
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2017
Optimal doses of Ribavirin (RBV) for hepatitis C virus (HCV) treatment are not known. To assess t... more Optimal doses of Ribavirin (RBV) for hepatitis C virus (HCV) treatment are not known. To assess the safety and efficacy of PegIFNalfa-2a in combination with an adjusted (ADJ) RBV dose based on early pharmacokinetics versus a fixed standard (STD) dose of RBV in chronic HCV genotype (GT) 4-naive patients in a randomized trial. One hundred eighty-one patients were randomized. The baseline variables were similar in both arms and females were 50.3% of the patients, 76.5% had minimal-moderate fibrosis (F0-2). Sustained virologic response (SVR) was achieved in 99 (54.7%) subjects. SVR was seen in 50/90 (55.6%) of ADJ dose of RBV and 49/91 (53.9%) of STD dose subjects. Prematurely withdrawal or discontinuation of treatment prematurely in the ADJ RBV arm occurred in 11/90 patients (12.2%) compared with 6/91 subjects (6.6%) in the STD arm (P = 0.214). Similarly, virologic relapse was seen in 14/90 (15.6%) patients of the ADJ arm and 12/91 (13.2%) of the STD arm. Anemia grade 3-4 was seen in 3...
The Professional Medical Journal
Objective: To analyze the biochemical composition and biochemical types ofurinary bladder stones ... more Objective: To analyze the biochemical composition and biochemical types ofurinary bladder stones in children. Study design and setting: Observational study, Departmentof Pediatric Surgery, Liaquat University of Medical and Health Sciences, Jamshoro/Hyderabad.Place and Duration: One year duration from January to December 2006. Materials &Methods: A sample of 30 children was selected according to criteria of inclusion of age <10years of urinary bladder stones without any anomaly. Urinary bladder stones were washed indistilled H2O deionized to remove contaminations. Urinary bladder stones were dried at 1000C for overnight in an oven. The urinary bladder stones cut into pieces were used for the FTIRspectroscopy analysis, carried out on “Nicolet Avatar 330 FTIR spectrophotometer”. Data wasanalyzed on SPSS 22.0 at 95% confidence interval. Results: Of 30, 6 (20%) were female and24 (80%) were male. The male dominancy was noted with male to female ratio of 4:1. Mean±SD age was noted as 4....
The Professional Medical Journal
over one year. Subjects & Methods: 30 pediatric cases urinary bladder urolithiasis were selected.... more over one year. Subjects & Methods: 30 pediatric cases urinary bladder urolithiasis were selected. Children of age few of ten years were selected. Any contamination form bladder stone was removed by washing them in distilled deionized water. Stones were dried for an overnight in an oven at temperature of 100 0 C. Dried stones were smashed into pieces. Biochemical analysis was performed by the FTIR spectroscopy (Nicolet Avatar 330 FTIR spectrophotometer). Results were analyzed on the software SPSS 22.0 (95% confidence interval). Results: Mean age was 4.83 years (SD 2.81 years). Of 30 children, 80% (n=24) were male and 20% (n=6) were female children. Male to female ratio of 4:1 was noted. 16.6% (n=5) were pure stone and 83.3% (n=25) were mixed stones. (P=0.0001). Biochemical analysis showed the calcium oxalate monohydrate (COM)-ammonium hydrogen urate (AHU) was the most common urinary bladder stone. Conclusions: The pediatric urolithiasis shows the most common type of urinary bladder stone was the calcium oxalate monohydrate-ammonium hydrogen urate.
The professional medical journal, Jul 10, 2018
over one year. Subjects & Methods: 30 pediatric cases urinary bladder urolithiasis were selected.... more over one year. Subjects & Methods: 30 pediatric cases urinary bladder urolithiasis were selected. Children of age few of ten years were selected. Any contamination form bladder stone was removed by washing them in distilled deionized water. Stones were dried for an overnight in an oven at temperature of 100 0 C. Dried stones were smashed into pieces. Biochemical analysis was performed by the FTIR spectroscopy (Nicolet Avatar 330 FTIR spectrophotometer). Results were analyzed on the software SPSS 22.0 (95% confidence interval). Results: Mean age was 4.83 years (SD 2.81 years). Of 30 children, 80% (n=24) were male and 20% (n=6) were female children. Male to female ratio of 4:1 was noted. 16.6% (n=5) were pure stone and 83.3% (n=25) were mixed stones. (P=0.0001). Biochemical analysis showed the calcium oxalate monohydrate (COM)-ammonium hydrogen urate (AHU) was the most common urinary bladder stone. Conclusions: The pediatric urolithiasis shows the most common type of urinary bladder stone was the calcium oxalate monohydrate-ammonium hydrogen urate.
Journal of Pharmaceutical Research International
Aim: To determine the correlation of HBA1c and serum cholesterol in diabetic patients. Methodolog... more Aim: To determine the correlation of HBA1c and serum cholesterol in diabetic patients. Methodology: This case control study was completed at the Biochemistry and Medicine Departments of Liaquat University Hospital Jamshoro from October 2015 to March 2016.Total number of study subject was 100 and they were divided into two groups. Group A (case group, n=50) comprises diagnosed T2DM subjects while group B (control group, n=50) consists of healthy normal subjects (HNS), healthy normal subjects with mean age 50±6.34 years. These subjects were assessed to find association of glycosylated hemoglobin with serum Cholesterol levels in Type-2 Diabetes mellitus patients. Those patients diagnosed asT2DM with age 30- 60years were included while those patients diagnosed as diabetic erectile dysfunction, diabetic nephropathy, diabetic renal failure, familial dyslipidemia, and hypercholesterolemia was excluded in this study. Blood specimens were collected from both groups aseptically then blood glu...
To analyze the biochemical composition and biochemical types of urinary bladder stones in childre... more To analyze the biochemical composition and biochemical types of urinary bladder stones in children. Study design and setting: Observational study,
Aim: To determine correlation of serum testosterone with low and high density lipoprotein in male... more Aim: To determine correlation of serum testosterone with low and high density lipoprotein in male type 2 Diabetics presenting at a tertiary care hospital of Sindh. Methodology: A cross sectional study, Department of Biochemistry and Department of Medicine, Liaquat University Hospital from January 2018 to February 2019. One hundred male type 2 diabetics (cases) and one hundred age matched male (control) were selected through non – probability purposive sampling. Male diagnosed cases of DM belonging to 4th to 6th decade of life was included. Blood samples were collected by venesection and sera were squeezed by centrifugation and stored at – 20 0C in refrigerators. Testosterone was estimated by the ELISA (competitive immuno- assay) assay method and blood lipids - cholesterol, triglycerides (TAGs), LDLc and HDLc by colorimetric method. Pearson`s correlation was generated on Statistical software SPSS 21.0 version (IBM, Incorp, USA) for correlation of serum testosterone with lipids fract...
Journal of Pharmaceutical Research International
Aim: To determine the serum testosterone levels in the type 2 diabetes mellitus and its correlati... more Aim: To determine the serum testosterone levels in the type 2 diabetes mellitus and its correlation with biochemical parameters of glycemic and lipid metabolism. Methodology: A cross sectional study was conducted at Department of Biochemistry and Department of Medicine, A cross sectional study was conducted at the Department of Biochemistry, Diabetic outpatient department and Department of Medicine, Liaquat University Hospital. Male type 2 diabetics (n=100) and age matched male (n=100) were included as cases and control for study purpose. Diagnosed cases of type 2 DM, male gender and 40 – 60 years of age were included in the study protocol. Physical examination of male type 2 diabetics was performed by a consultant physician. Sera were separated from blood and stored in refrigerators at – 200C. Blood glucose, A1C, and blood lipids (cholesterol, triglycerides, LDLc and HDLc) were detected by standard laboratory methods. Serum testosterone was measured by ELISA (competitive immuno- as...
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2017
Optimal doses of Ribavirin (RBV) for hepatitis C virus (HCV) treatment are not known. To assess t... more Optimal doses of Ribavirin (RBV) for hepatitis C virus (HCV) treatment are not known. To assess the safety and efficacy of PegIFNalfa-2a in combination with an adjusted (ADJ) RBV dose based on early pharmacokinetics versus a fixed standard (STD) dose of RBV in chronic HCV genotype (GT) 4-naive patients in a randomized trial. One hundred eighty-one patients were randomized. The baseline variables were similar in both arms and females were 50.3% of the patients, 76.5% had minimal-moderate fibrosis (F0-2). Sustained virologic response (SVR) was achieved in 99 (54.7%) subjects. SVR was seen in 50/90 (55.6%) of ADJ dose of RBV and 49/91 (53.9%) of STD dose subjects. Prematurely withdrawal or discontinuation of treatment prematurely in the ADJ RBV arm occurred in 11/90 patients (12.2%) compared with 6/91 subjects (6.6%) in the STD arm (P = 0.214). Similarly, virologic relapse was seen in 14/90 (15.6%) patients of the ADJ arm and 12/91 (13.2%) of the STD arm. Anemia grade 3-4 was seen in 3...
The Professional Medical Journal
Objective: To analyze the biochemical composition and biochemical types ofurinary bladder stones ... more Objective: To analyze the biochemical composition and biochemical types ofurinary bladder stones in children. Study design and setting: Observational study, Departmentof Pediatric Surgery, Liaquat University of Medical and Health Sciences, Jamshoro/Hyderabad.Place and Duration: One year duration from January to December 2006. Materials &Methods: A sample of 30 children was selected according to criteria of inclusion of age <10years of urinary bladder stones without any anomaly. Urinary bladder stones were washed indistilled H2O deionized to remove contaminations. Urinary bladder stones were dried at 1000C for overnight in an oven. The urinary bladder stones cut into pieces were used for the FTIRspectroscopy analysis, carried out on “Nicolet Avatar 330 FTIR spectrophotometer”. Data wasanalyzed on SPSS 22.0 at 95% confidence interval. Results: Of 30, 6 (20%) were female and24 (80%) were male. The male dominancy was noted with male to female ratio of 4:1. Mean±SD age was noted as 4....
The Professional Medical Journal
over one year. Subjects & Methods: 30 pediatric cases urinary bladder urolithiasis were selected.... more over one year. Subjects & Methods: 30 pediatric cases urinary bladder urolithiasis were selected. Children of age few of ten years were selected. Any contamination form bladder stone was removed by washing them in distilled deionized water. Stones were dried for an overnight in an oven at temperature of 100 0 C. Dried stones were smashed into pieces. Biochemical analysis was performed by the FTIR spectroscopy (Nicolet Avatar 330 FTIR spectrophotometer). Results were analyzed on the software SPSS 22.0 (95% confidence interval). Results: Mean age was 4.83 years (SD 2.81 years). Of 30 children, 80% (n=24) were male and 20% (n=6) were female children. Male to female ratio of 4:1 was noted. 16.6% (n=5) were pure stone and 83.3% (n=25) were mixed stones. (P=0.0001). Biochemical analysis showed the calcium oxalate monohydrate (COM)-ammonium hydrogen urate (AHU) was the most common urinary bladder stone. Conclusions: The pediatric urolithiasis shows the most common type of urinary bladder stone was the calcium oxalate monohydrate-ammonium hydrogen urate.