Naser Karimi | Razi University of Kermanshah, Iran (original) (raw)
Papers by Naser Karimi
Food Science and Technology
Animals
Hypocalcaemia is an important disorder associated with an increased risk of metabolic diseases, a... more Hypocalcaemia is an important disorder associated with an increased risk of metabolic diseases, and many studies have been going on for decades. This study investigated the effects of anionic and zeolite with an oral Ca bolus in the prepartum phase on milk yields and compositions, and plasma Ca concentrations, blood metabolites and the prevalence of some reproductive disorders in dairy cows after parturition. Ninety pregnant non-lactating Holstein-Friesian cows were randomly assigned to three isoenergetic diets and their counterparts using an oral Ca bolus: (1) Control (CON): low Ca (0.44%); (2) Anionic (ANI): high Ca (1.00%); (3) Zeolite (ZEO): low Ca (0.44%). The feed and energy intakes of the CON and ZEO groups were higher than the ANI group. The raw milk yield, Pr%, and feed efficiency did not differ between the groups, while the corrected milk yield, fat% and total corrected milk yield at 305 days differed between groups. Total plasma and the ionized Ca concentration of the ANI...
Journal of Biochemical and Molecular Toxicology, 2012
The present study was planned to investigate the effect of arsenic in rats on several biochemical... more The present study was planned to investigate the effect of arsenic in rats on several biochemical indices of oxidative stress. Rats were exposed to arsenite in drinking water for upto 12 weeks. Chronic exposure to arsenic for a period of 12 weeks significantly (p < 0.05) increased arsenic burden in blood, liver, and kidney. Several intrinsic antioxidant defenses were activated after a 4‐week exposure to arsenic. Some remained elevated, but others became depressed over a longer exposure period. Alterations in most of the biochemical variables reached statistical significant (p < 0.05). Arsenic significantly (p < 0.01) reduced mRNA expression of the superoxide dismutase 2 (SOD2) gene with respect to the glyceraldehyde 3‐phosphate dehydrogenase (GAPDH) gene. These observations indicated that prolong exposure to arsenic causes induction of oxidative stress and biochemical alterations. © 2012 Wiley Periodicals, Inc. J Biochem Mol Toxicol 26:101–116, 2012; View this article onlin...
International Journal of Environmental Science and Technology, Mar 1, 2011
Indian journal of science and technology, Nov 20, 2012
PubMed, 2017
The biogenic synthesis of metal nanomaterial offers an environmentally benign alternative to the ... more The biogenic synthesis of metal nanomaterial offers an environmentally benign alternative to the traditional chemical synthesis routes. In the present study, the green synthesis of silver nanoparticles (AgNPs) from aqueous solution of silver nitrate (AgNO3) by using Nigella arvensis L. seed powder extract (NSPE) has been reported. AgNPs were characterized by UV-vis absorption spectroscopy with an intense surface plasmon resonance band at 435 nm which reveals the formation of nanoparticles. Fourier transmission infrared spectroscopy (FTIR) showed that nanoparticles were capped with plant compounds. Transmission electron microscopy (TEM) showed silver nanoparticles, with a size of 2-15 nm, were spherical. The X-ray diffraction spectrum (XRD) pattern clearly indicates that AgNPs formed in the present synthesis were crystalline in nature. Stabilized films of exudate synthesized AgNPs were effective anti-bacterial agents. In addition, these biologically synthesized nanoparticles were also proved to exhibit excellent cytotoxic effect on a human breast cancer cell line (MCF-7) and a human colorectal adenocarcinoma cell line (HT-29). The results confirmed that the NSPE is a very good ecofriendly and nontoxic source for the synthesis of AgNPs as compared to the conventional chemical/physical methods. Therefore, N. arvensis seed provides future opportunities in nanomedicine by tagging nanoparticles with secondary metabolites.
Applied sciences, Mar 2, 2016
This paper reports a novel green approach for the synthesis of silver nanoparticles (AgNPs) using... more This paper reports a novel green approach for the synthesis of silver nanoparticles (AgNPs) using aqueous seed extract of Dracocephalum moldavica (L.) under ambient conditions. Processes such as Ultraviolet-visible (UV-vis) spectrometer, field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), energy dispersive X-ray analysis (EDX), and transmission electron microscopy (TEM) were carry out to characterize AgNPs. The presence of AgNPs in the prepared solution was approved by a peak to occur at 443 nm. XRD pattern indicated the crystalline structure of the nanoparticles (NPs) while the FTIR spectra confirm the attendance of plant residues adsorbed by these NPs. TEM images revealed a near spherical shape of these NPs, and EDX provided the expected elemental composition. The synthesized AgNPs showed excellent antimicrobial activities against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Serratia marcescens, Staphylococcus epidermidis and Bacillus subtilis.
Journal of Biomedical Materials Research Part A, Dec 6, 2018
Artificial Cells Nanomedicine and Biotechnology, May 25, 2017
Korean Journal of Chemical Engineering, Jan 21, 2017
Microalgae are considered the biological drug factories of the future. To benefit from these micr... more Microalgae are considered the biological drug factories of the future. To benefit from these microfactories, the intracellular metabolite of algae should be extracted. One of the most economically competitive methods is the ultrasound technique. This study was concerned with ultrasound-assisted extractions of useful substances from microalgae by comparing direct and indirect irradiation methods with respect to the extraction rate and yields. It is most likely that the direct and indirect irradiations had different irradiation powers. The systems were exposed to ultrasound wave (1.7 MHz) for 240min. For each system, the changes of optical density, concentration and biovolume of Chlorella were estimated. In addition, the concentration of extracted chlorophylls (a, b and a+b), carotenoid and lipid were measured. The factors were studied after 30, 60, 120, 180 and 240 min of exposure to ultrasound irradiation. Both direct and indirect irradiation systems produced cavitation in the cell membrane, and they reduced the concentration and biovolume of the Chlorella cells. The amount of lipids and chlorophylls was greater in the direct irradiation as compared to the indirect one, and it caused more cell disruption. However, the extraction of the carotenoid was less effective because direct irradiation produced more transmitted power of ultrasound, resulting in degradation of carotenoid. The results and analysis presented in this research showed that selection of the best method of irradiation is an important step, and it depends on the biomaterials to be extracted.
Scientific Reports, Mar 2, 2020
The effects of different concentrations (0, 50,100, 1000 and 2500 mg/L) of engineered aluminum an... more The effects of different concentrations (0, 50,100, 1000 and 2500 mg/L) of engineered aluminum and nickel oxide nanoparticles (Al 2 o 3 and NiO NPs) on plant growth, oxidative stress and antioxidant activities in the hydroponically grown tissues of Nigella arvensis L. were investigated. The plant biomass was significantly increased under 50 and 100 mg/L of Al 2 o 3 NPs or 50 mg/L of NiO NPs treatment, but was significantly decreased at higher concentrations of these nanoparticles. Assays of several enzymatic antioxidants such as ascorbate peroxidase (APX), catalase (CAT), superoxide dismutase (SOD) and peroxidase (POD) in roots and shoots indicate a general increase of activities after exposure to 50-2,500 mg/L of Al 2 o 3 NPs and NiO NPs. The results are corroborated by an increased 2,2-diphenyl-1-picryl hydrazyl (DPPH) scavenging activity, total antioxidant capacity, total reducing power, total iridoids content, total saponin content, and total phenolic content in treated plants by Al 2 o 3 NPs compared to the control plants. By contrast, the antioxidant activities, formation of secondary metabolites, and other related physiological parameters such as the total antioxidant capacity, DPPH scavenging activity and total saponin content were inhibited after the concentration of NiO NPs was increased to 100 mg/L. Total phenols, saponins, iridoids and total antioxidant content and DPPH scavenging activity were increased in plants treated with 100-2,500 mg/L Al 2 o 3 NPs. Overall, these two nanoparticles displayed different effects in the shoots and roots of plants at different concentrations, which may be due to their physico-chemical properties. Rapid development of nanotechnology has greatly expanded the applications of engineered nanoparticles (ENPs) in commercial and industrial products 1. Increased application and potential accumulation of ENPs in the environment and their unknown interactions with different organisms, aggravated by some reports of greater toxicity at nanoscale than the bulk scale, caused broad concerns about the environmental health and safety of ENPs 2,3. Previous studies have demonstrated some disruptive effects of some ENPs on the natural environment including water, air, and soil quality 4. Plants are one of the most essential components of the ecosystem and interact with ENPs closely 5. These ENPs could be taken up by plants, and enter into the food chain through dietary consumption, ultimately affecting human health 6. Many previous investigations explored the potential applications of ENPs in agriculture 7-10. However, the majority of previous studies in ENPs-plant interactions focused on the potential toxicity of nanoparticles to higher plants. Both positive and negative or insignificant effects of ENPs on plants have been reported 11. In general, the phytotoxicity of ENPs is mediated through the production of reactive oxygen species (ROS) in plant cells 12. Even though ROS are normally produced within plants as a byproduct of metabolic processes in chloroplasts and other organelles 13,14 , excessive production of ROS can disrupt plant photosynthesis and other physiological and biochemical processes, eventually triggering the defense mechanisms in plants such as greater activities of certain antioxidants 15. In addition, accumulation of ENPs can stimulate defense mechanisms through antioxidant enzymes to scavenge the deleterious ROS 16 .
Materials Technology, Jul 20, 2020
In this research, an aqueous extract of Daphne mucronata leaves with different salt sources inclu... more In this research, an aqueous extract of Daphne mucronata leaves with different salt sources including Zn(NO 3) 2 and ZnSO 4 solutions were used to synthesize ZnO-N and ZnO-S NPs, respectively. The physicochemical, antibacterial, antioxidant, and cytotoxic properties of these NPs were also surveyed. SEM and TEM images confirmed that the ZnO-N and ZnO-S NPs were polydispersed with spherical and plate shape and average diameters of 129 ± 45.49 nm and 87 ± 31.61 nm, respectively. The minimum bactericidal concentration (MBC) values for both NPs against bacterial strains were 2 mg/ml. The biofilm growth in biofilm producer strains was completely inhibited at minimum inhibitory concentration (MIC). The IC50 values for ZnO-N and ZnO-S NPs were calculated as 1.946 mg/ml and 0.369 mg/ml, respectively. Finally, due to the antioxidant, antimicrobial, and cytotoxic properties of zinc oxide NPs, green synthesis of ZnONPs using D. mucronata can improve their applications in a wide range of clinical areas.
Advanced Powder Technology, 2018
Indian journal of science and technology, May 20, 2012
Effect of NaCl salinity on germination, physiological and biochemical parameters of Plantago ovat... more Effect of NaCl salinity on germination, physiological and biochemical parameters of Plantago ovata Forsk.
Journal of Industrial and Engineering Chemistry, Apr 1, 2019
It was used green biosynthesized zinc oxide (ZnO) NPs (average diameter of 50-60 nm) with abiliti... more It was used green biosynthesized zinc oxide (ZnO) NPs (average diameter of 50-60 nm) with abilities of antibacterial against MDR bacteria including Escherichia coli ATCC 25922, Serratia marcescens ATCC13880, Pseudomonas aeruginosa ATCC 27853 (gram negative), and Staphylococcus aureus ATCC 43300 and Staphylococcus epidermidis ATCC 12258 (gram positive). High reduction in biofilm formation was 63.43% (0.562±0.015) and 62.88% (0.582±0.025) at 100 μg/mL concentration against control for S. epedermidis and P. aeruginosa respectively. In conclusion, this investigation illustrated simple green synthesis of ZnO NPs with suitable advantages of antioxidant, antibacterial, anti-biofilm, anti-QS activities, and also antiswarming motility against MDR bacteria.
Artificial Cells Nanomedicine and Biotechnology, Dec 12, 2017
Food Science and Technology
Animals
Hypocalcaemia is an important disorder associated with an increased risk of metabolic diseases, a... more Hypocalcaemia is an important disorder associated with an increased risk of metabolic diseases, and many studies have been going on for decades. This study investigated the effects of anionic and zeolite with an oral Ca bolus in the prepartum phase on milk yields and compositions, and plasma Ca concentrations, blood metabolites and the prevalence of some reproductive disorders in dairy cows after parturition. Ninety pregnant non-lactating Holstein-Friesian cows were randomly assigned to three isoenergetic diets and their counterparts using an oral Ca bolus: (1) Control (CON): low Ca (0.44%); (2) Anionic (ANI): high Ca (1.00%); (3) Zeolite (ZEO): low Ca (0.44%). The feed and energy intakes of the CON and ZEO groups were higher than the ANI group. The raw milk yield, Pr%, and feed efficiency did not differ between the groups, while the corrected milk yield, fat% and total corrected milk yield at 305 days differed between groups. Total plasma and the ionized Ca concentration of the ANI...
Journal of Biochemical and Molecular Toxicology, 2012
The present study was planned to investigate the effect of arsenic in rats on several biochemical... more The present study was planned to investigate the effect of arsenic in rats on several biochemical indices of oxidative stress. Rats were exposed to arsenite in drinking water for upto 12 weeks. Chronic exposure to arsenic for a period of 12 weeks significantly (p < 0.05) increased arsenic burden in blood, liver, and kidney. Several intrinsic antioxidant defenses were activated after a 4‐week exposure to arsenic. Some remained elevated, but others became depressed over a longer exposure period. Alterations in most of the biochemical variables reached statistical significant (p < 0.05). Arsenic significantly (p < 0.01) reduced mRNA expression of the superoxide dismutase 2 (SOD2) gene with respect to the glyceraldehyde 3‐phosphate dehydrogenase (GAPDH) gene. These observations indicated that prolong exposure to arsenic causes induction of oxidative stress and biochemical alterations. © 2012 Wiley Periodicals, Inc. J Biochem Mol Toxicol 26:101–116, 2012; View this article onlin...
International Journal of Environmental Science and Technology, Mar 1, 2011
Indian journal of science and technology, Nov 20, 2012
PubMed, 2017
The biogenic synthesis of metal nanomaterial offers an environmentally benign alternative to the ... more The biogenic synthesis of metal nanomaterial offers an environmentally benign alternative to the traditional chemical synthesis routes. In the present study, the green synthesis of silver nanoparticles (AgNPs) from aqueous solution of silver nitrate (AgNO3) by using Nigella arvensis L. seed powder extract (NSPE) has been reported. AgNPs were characterized by UV-vis absorption spectroscopy with an intense surface plasmon resonance band at 435 nm which reveals the formation of nanoparticles. Fourier transmission infrared spectroscopy (FTIR) showed that nanoparticles were capped with plant compounds. Transmission electron microscopy (TEM) showed silver nanoparticles, with a size of 2-15 nm, were spherical. The X-ray diffraction spectrum (XRD) pattern clearly indicates that AgNPs formed in the present synthesis were crystalline in nature. Stabilized films of exudate synthesized AgNPs were effective anti-bacterial agents. In addition, these biologically synthesized nanoparticles were also proved to exhibit excellent cytotoxic effect on a human breast cancer cell line (MCF-7) and a human colorectal adenocarcinoma cell line (HT-29). The results confirmed that the NSPE is a very good ecofriendly and nontoxic source for the synthesis of AgNPs as compared to the conventional chemical/physical methods. Therefore, N. arvensis seed provides future opportunities in nanomedicine by tagging nanoparticles with secondary metabolites.
Applied sciences, Mar 2, 2016
This paper reports a novel green approach for the synthesis of silver nanoparticles (AgNPs) using... more This paper reports a novel green approach for the synthesis of silver nanoparticles (AgNPs) using aqueous seed extract of Dracocephalum moldavica (L.) under ambient conditions. Processes such as Ultraviolet-visible (UV-vis) spectrometer, field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), energy dispersive X-ray analysis (EDX), and transmission electron microscopy (TEM) were carry out to characterize AgNPs. The presence of AgNPs in the prepared solution was approved by a peak to occur at 443 nm. XRD pattern indicated the crystalline structure of the nanoparticles (NPs) while the FTIR spectra confirm the attendance of plant residues adsorbed by these NPs. TEM images revealed a near spherical shape of these NPs, and EDX provided the expected elemental composition. The synthesized AgNPs showed excellent antimicrobial activities against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Serratia marcescens, Staphylococcus epidermidis and Bacillus subtilis.
Journal of Biomedical Materials Research Part A, Dec 6, 2018
Artificial Cells Nanomedicine and Biotechnology, May 25, 2017
Korean Journal of Chemical Engineering, Jan 21, 2017
Microalgae are considered the biological drug factories of the future. To benefit from these micr... more Microalgae are considered the biological drug factories of the future. To benefit from these microfactories, the intracellular metabolite of algae should be extracted. One of the most economically competitive methods is the ultrasound technique. This study was concerned with ultrasound-assisted extractions of useful substances from microalgae by comparing direct and indirect irradiation methods with respect to the extraction rate and yields. It is most likely that the direct and indirect irradiations had different irradiation powers. The systems were exposed to ultrasound wave (1.7 MHz) for 240min. For each system, the changes of optical density, concentration and biovolume of Chlorella were estimated. In addition, the concentration of extracted chlorophylls (a, b and a+b), carotenoid and lipid were measured. The factors were studied after 30, 60, 120, 180 and 240 min of exposure to ultrasound irradiation. Both direct and indirect irradiation systems produced cavitation in the cell membrane, and they reduced the concentration and biovolume of the Chlorella cells. The amount of lipids and chlorophylls was greater in the direct irradiation as compared to the indirect one, and it caused more cell disruption. However, the extraction of the carotenoid was less effective because direct irradiation produced more transmitted power of ultrasound, resulting in degradation of carotenoid. The results and analysis presented in this research showed that selection of the best method of irradiation is an important step, and it depends on the biomaterials to be extracted.
Scientific Reports, Mar 2, 2020
The effects of different concentrations (0, 50,100, 1000 and 2500 mg/L) of engineered aluminum an... more The effects of different concentrations (0, 50,100, 1000 and 2500 mg/L) of engineered aluminum and nickel oxide nanoparticles (Al 2 o 3 and NiO NPs) on plant growth, oxidative stress and antioxidant activities in the hydroponically grown tissues of Nigella arvensis L. were investigated. The plant biomass was significantly increased under 50 and 100 mg/L of Al 2 o 3 NPs or 50 mg/L of NiO NPs treatment, but was significantly decreased at higher concentrations of these nanoparticles. Assays of several enzymatic antioxidants such as ascorbate peroxidase (APX), catalase (CAT), superoxide dismutase (SOD) and peroxidase (POD) in roots and shoots indicate a general increase of activities after exposure to 50-2,500 mg/L of Al 2 o 3 NPs and NiO NPs. The results are corroborated by an increased 2,2-diphenyl-1-picryl hydrazyl (DPPH) scavenging activity, total antioxidant capacity, total reducing power, total iridoids content, total saponin content, and total phenolic content in treated plants by Al 2 o 3 NPs compared to the control plants. By contrast, the antioxidant activities, formation of secondary metabolites, and other related physiological parameters such as the total antioxidant capacity, DPPH scavenging activity and total saponin content were inhibited after the concentration of NiO NPs was increased to 100 mg/L. Total phenols, saponins, iridoids and total antioxidant content and DPPH scavenging activity were increased in plants treated with 100-2,500 mg/L Al 2 o 3 NPs. Overall, these two nanoparticles displayed different effects in the shoots and roots of plants at different concentrations, which may be due to their physico-chemical properties. Rapid development of nanotechnology has greatly expanded the applications of engineered nanoparticles (ENPs) in commercial and industrial products 1. Increased application and potential accumulation of ENPs in the environment and their unknown interactions with different organisms, aggravated by some reports of greater toxicity at nanoscale than the bulk scale, caused broad concerns about the environmental health and safety of ENPs 2,3. Previous studies have demonstrated some disruptive effects of some ENPs on the natural environment including water, air, and soil quality 4. Plants are one of the most essential components of the ecosystem and interact with ENPs closely 5. These ENPs could be taken up by plants, and enter into the food chain through dietary consumption, ultimately affecting human health 6. Many previous investigations explored the potential applications of ENPs in agriculture 7-10. However, the majority of previous studies in ENPs-plant interactions focused on the potential toxicity of nanoparticles to higher plants. Both positive and negative or insignificant effects of ENPs on plants have been reported 11. In general, the phytotoxicity of ENPs is mediated through the production of reactive oxygen species (ROS) in plant cells 12. Even though ROS are normally produced within plants as a byproduct of metabolic processes in chloroplasts and other organelles 13,14 , excessive production of ROS can disrupt plant photosynthesis and other physiological and biochemical processes, eventually triggering the defense mechanisms in plants such as greater activities of certain antioxidants 15. In addition, accumulation of ENPs can stimulate defense mechanisms through antioxidant enzymes to scavenge the deleterious ROS 16 .
Materials Technology, Jul 20, 2020
In this research, an aqueous extract of Daphne mucronata leaves with different salt sources inclu... more In this research, an aqueous extract of Daphne mucronata leaves with different salt sources including Zn(NO 3) 2 and ZnSO 4 solutions were used to synthesize ZnO-N and ZnO-S NPs, respectively. The physicochemical, antibacterial, antioxidant, and cytotoxic properties of these NPs were also surveyed. SEM and TEM images confirmed that the ZnO-N and ZnO-S NPs were polydispersed with spherical and plate shape and average diameters of 129 ± 45.49 nm and 87 ± 31.61 nm, respectively. The minimum bactericidal concentration (MBC) values for both NPs against bacterial strains were 2 mg/ml. The biofilm growth in biofilm producer strains was completely inhibited at minimum inhibitory concentration (MIC). The IC50 values for ZnO-N and ZnO-S NPs were calculated as 1.946 mg/ml and 0.369 mg/ml, respectively. Finally, due to the antioxidant, antimicrobial, and cytotoxic properties of zinc oxide NPs, green synthesis of ZnONPs using D. mucronata can improve their applications in a wide range of clinical areas.
Advanced Powder Technology, 2018
Indian journal of science and technology, May 20, 2012
Effect of NaCl salinity on germination, physiological and biochemical parameters of Plantago ovat... more Effect of NaCl salinity on germination, physiological and biochemical parameters of Plantago ovata Forsk.
Journal of Industrial and Engineering Chemistry, Apr 1, 2019
It was used green biosynthesized zinc oxide (ZnO) NPs (average diameter of 50-60 nm) with abiliti... more It was used green biosynthesized zinc oxide (ZnO) NPs (average diameter of 50-60 nm) with abilities of antibacterial against MDR bacteria including Escherichia coli ATCC 25922, Serratia marcescens ATCC13880, Pseudomonas aeruginosa ATCC 27853 (gram negative), and Staphylococcus aureus ATCC 43300 and Staphylococcus epidermidis ATCC 12258 (gram positive). High reduction in biofilm formation was 63.43% (0.562±0.015) and 62.88% (0.582±0.025) at 100 μg/mL concentration against control for S. epedermidis and P. aeruginosa respectively. In conclusion, this investigation illustrated simple green synthesis of ZnO NPs with suitable advantages of antioxidant, antibacterial, anti-biofilm, anti-QS activities, and also antiswarming motility against MDR bacteria.
Artificial Cells Nanomedicine and Biotechnology, Dec 12, 2017