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pathway_id pathway_name go_term go_term_name R-HSA-73843 5-Phosphoribose 1-diphosphate biosynthesis 6015 5-phosphoribose 1-diphosphate biosynthetic process R-HSA-1369062 ABC transporters in lipid homeostasis 6869 lipid transport R-HSA-382556 ABC-family proteins mediated transport 55085 transmembrane transport R-HSA-9660821 ADORA2B mediated anti-inflammatory cytokines production 2862 negative regulation of inflammatory response to antigenic stimulus R-HSA-418592 ADP signalling through P2Y purinoceptor 1 30168 platelet activation R-HSA-392170 ADP signalling through P2Y purinoceptor 12 30168 platelet activation R-HSA-198323 AKT phosphorylates targets in the cytosol 43491 phosphatidylinositol 3-kinase/protein kinase B signal transduction R-HSA-198693 AKT phosphorylates targets in the nucleus 43491 phosphatidylinositol 3-kinase/protein kinase B signal transduction R-HSA-211163 AKT-mediated inactivation of FOXO1A 2000074 regulation of type B pancreatic cell development R-HSA-163680 AMPK inhibits chREBP transcriptional activation activity 42304 regulation of fatty acid biosynthetic process R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 31145 anaphase-promoting complex-dependent catabolic process R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 31145 anaphase-promoting complex-dependent catabolic process R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 31145 anaphase-promoting complex-dependent catabolic process R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 7096 regulation of exit from mitosis R-HSA-381033 ATF6 (ATF6-alpha) activates chaperones 36500 ATF6-mediated unfolded protein response R-HSA-8854518 AURKA Activation by TPX2 10389 regulation of G2/M transition of mitotic cell cycle R-HSA-2161541 Abacavir metabolism 6805 xenobiotic metabolic process R-HSA-2161517 Abacavir transmembrane transport 72530 purine-containing compound transmembrane transport R-HSA-73930 Abasic sugar-phosphate removal via the single-nucleotide replacement pathway 6284 base-excision repair R-HSA-2978092 Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate 6103 2-oxoglutarate metabolic process R-HSA-264642 Acetylcholine Neurotransmitter Release Cycle 6836 neurotransmitter transport R-HSA-399997 Acetylcholine regulates insulin secretion 32024 positive regulation of insulin secretion R-HSA-1300645 Acrosome Reaction and Sperm:Oocyte Membrane Binding 7340 acrosome reaction R-HSA-9032845 Activated NTRK2 signals through CDK5 1902949 positive regulation of tau-protein kinase activity R-HSA-9028335 Activated NTRK2 signals through PI3K 51897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction R-HSA-9026527 Activated NTRK2 signals through PLCG1 7202 activation of phospholipase C activity R-HSA-9026519 Activated NTRK2 signals through RAS 46579 positive regulation of Ras protein signal transduction R-HSA-9603381 Activated NTRK3 signals through PI3K 51897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction R-HSA-9034793 Activated NTRK3 signals through PLCG1 51388 positive regulation of neurotrophin TRK receptor signaling pathway R-HSA-9034864 Activated NTRK3 signals through RAS 46579 positive regulation of Ras protein signal transduction R-HSA-5625886 Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 60765 regulation of androgen receptor signaling pathway R-HSA-111452 Activation and oligomerization of BAK protein 1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway R-HSA-165158 Activation of AKT2 51897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction R-HSA-9619483 Activation of AMPK downstream of NMDARs 7268 chemical synaptic transmission R-HSA-176187 Activation of ATR in response to replication stress 6260 DNA replication R-HSA-114452 Activation of BH3-only proteins 1903749 positive regulation of establishment of protein localization to mitochondrion R-HSA-451308 Activation of Ca-permeable Kainate Receptor 7268 chemical synaptic transmission R-HSA-1296041 Activation of G protein gated Potassium channels 1901381 positive regulation of potassium ion transmembrane transport R-HSA-5619507 Activation of HOX genes during differentiation 9790 embryo development R-HSA-451307 Activation of Na-permeable kainate receptors 7268 chemical synaptic transmission R-HSA-428540 Activation of RAC1 16601 Rac protein signal transduction R-HSA-9619229 Activation of RAC1 downstream of NMDARs 7268 chemical synaptic transmission R-HSA-1169092 Activation of RAS in B cells 7265 Ras protein signal transduction R-HSA-187015 Activation of TRKA receptors 7169 cell surface receptor protein tyrosine kinase signaling pathway R-HSA-111459 Activation of caspases through apoptosome-mediated cleavage 8635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c R-HSA-2426168 Activation of gene expression by SREBF (SREBP) 19216 regulation of lipid metabolic process R-HSA-8866907 Activation of the TFAP2 (AP-2) family of transcription factors 45944 positive regulation of transcription by RNA polymerase II R-HSA-68962 Activation of the pre-replicative complex 6270 DNA replication initiation R-HSA-75108 Activation, myristolyation of BID and translocation to mitochondria 1903749 positive regulation of establishment of protein localization to mitochondrion R-HSA-114294 Activation, translocation and oligomerization of BAX 1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway R-HSA-1482798 Acyl chain remodeling of CL 35965 cardiolipin acyl-chain remodeling R-HSA-1482883 Acyl chain remodeling of DAG and TAG 36155 acylglycerol acyl-chain remodeling R-HSA-1482788 Acyl chain remodelling of PC 36151 phosphatidylcholine acyl-chain remodeling R-HSA-1482839 Acyl chain remodelling of PE 36152 phosphatidylethanolamine acyl-chain remodeling R-HSA-1482925 Acyl chain remodelling of PG 36148 phosphatidylglycerol acyl-chain remodeling R-HSA-1482922 Acyl chain remodelling of PI 36149 phosphatidylinositol acyl-chain remodeling R-HSA-1482801 Acyl chain remodelling of PS 36150 phosphatidylserine acyl-chain remodeling R-HSA-1280218 Adaptive Immune System 2250 adaptive immune response R-HSA-170660 Adenylate cyclase activating pathway 7189 adenylate cyclase-activating G protein-coupled receptor signaling pathway R-HSA-170670 Adenylate cyclase inhibitory pathway 7193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway R-HSA-418990 Adherens junctions interactions 34332 adherens junction organization R-HSA-9843745 Adipogenesis 1904177 regulation of adipose tissue development R-HSA-392023 Adrenaline signalling through Alpha-2 adrenergic receptor 30168 platelet activation R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 46676 negative regulation of insulin secretion R-HSA-1428517 Aerobic respiration and respiratory electron transport 44237 cellular metabolic process R-HSA-5423646 Aflatoxin activation and detoxification 46222 aflatoxin metabolic process R-HSA-9646399 Aggrephagy 35973 aggrephagy R-HSA-351143 Agmatine biosynthesis 97055 agmatine biosynthetic process R-HSA-8964540 Alanine metabolism 9078 pyruvate family amino acid metabolic process R-HSA-389599 Alpha-oxidation of phytanate 1561 fatty acid alpha-oxidation R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 2753 cytoplasmic pattern recognition receptor signaling pathway R-HSA-173736 Alternative complement activation 6957 complement activation, alternative pathway R-HSA-352230 Amino acid transport across the plasma membrane 6865 amino acid transport R-HSA-9639288 Amino acids regulate mTORC1 34198 cellular response to amino acid starvation R-HSA-977225 Amyloid fiber formation 1990000 amyloid fibril formation R-HSA-2214320 Anchoring fibril formation 30199 collagen fibril organization R-HSA-5620912 Anchoring of the basal body to the plasma membrane 97711 ciliary basal body-plasma membrane docking R-HSA-193048 Androgen biosynthesis 6702 androgen biosynthetic process R-HSA-9662851 Anti-inflammatory response favouring Leishmania parasite infection 51711 negative regulation of killing of cells of another organism R-HSA-1236975 Antigen processing-Cross presentation 42590 antigen processing and presentation of exogenous peptide antigen via MHC class I R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 209 protein polyubiquitination R-HSA-9639775 Antimicrobial action and antimicrobial resistance in Mtb 46677 response to antibiotic R-HSA-6803157 Antimicrobial peptides 19730 antimicrobial humoral response R-HSA-109581 Apoptosis 6915 apoptotic process R-HSA-140342 Apoptosis induced DNA fragmentation 6309 apoptotic DNA fragmentation R-HSA-75153 Apoptotic execution phase 97194 execution phase of apoptosis R-HSA-445717 Aquaporin-mediated transport 6833 water transport R-HSA-426048 Arachidonate production from DAG 19369 arachidonic acid metabolic process R-HSA-2142753 Arachidonic acid metabolism 19369 arachidonic acid metabolic process R-HSA-446203 Asparagine N-linked glycosylation 18279 protein N-linked glycosylation via asparagine R-HSA-8963693 Aspartate and asparagine metabolism 9066 aspartate family amino acid metabolic process R-HSA-175474 Assembly Of The HIV Virion 19068 virion assembly R-HSA-168316 Assembly of Viral Components at the Budding Site 19068 virion assembly R-HSA-68867 Assembly of the pre-replicative complex 36388 pre-replicative complex assembly R-HSA-162791 Attachment of GPI anchor to uPAR 16255 attachment of GPI anchor to protein R-HSA-9612973 Autophagy 6914 autophagy R-HSA-422475 Axon guidance 7411 axon guidance R-HSA-193634 Axonal growth inhibition (RHOA activation) 50771 negative regulation of axonogenesis R-HSA-209563 Axonal growth stimulation 50772 positive regulation of axonogenesis R-HSA-9024909 BDNF activates NTRK2 (TRKB) signaling 51388 positive regulation of neurotrophin TRK receptor signaling pathway R-HSA-111453 BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members 2001244 positive regulation of intrinsic apoptotic signaling pathway R-HSA-9824439 Bacterial Infection Pathways 9617 response to bacterium R-HSA-73884 Base Excision Repair 6284 base-excision repair R-HSA-73929 Base-Excision Repair, AP Site Formation 6285 base-excision repair, AP site formation R-HSA-3858494 Beta-catenin independent WNT signaling 35567 non-canonical Wnt signaling pathway R-HSA-389887 Beta-oxidation of pristanoyl-CoA 33540 fatty acid beta-oxidation using acyl-CoA oxidase R-HSA-390247 Beta-oxidation of very long chain fatty acids 33540 fatty acid beta-oxidation using acyl-CoA oxidase R-HSA-425381 Bicarbonate transporters 15701 bicarbonate transport R-HSA-194068 Bile acid and bile salt metabolism 8206 bile acid metabolic process R-HSA-2173782 Binding and Uptake of Ligands by Scavenger Receptors 6898 receptor-mediated endocytosis R-HSA-173107 Binding and entry of HIV virion 44409 symbiont entry into host R-HSA-211859 Biological oxidations 6805 xenobiotic metabolic process R-HSA-9018677 Biosynthesis of DHA-derived SPMs 42759 long-chain fatty acid biosynthetic process R-HSA-9018683 Biosynthesis of DPA-derived SPMs 42759 long-chain fatty acid biosynthetic process R-HSA-9025094 Biosynthesis of DPAn-3 SPMs 19372 lipoxygenase pathway R-HSA-9026403 Biosynthesis of DPAn-3-derived 13-series resolvins 42759 long-chain fatty acid biosynthetic process R-HSA-9018679 Biosynthesis of EPA-derived SPMs 42759 long-chain fatty acid biosynthetic process R-HSA-9027604 Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives 42759 long-chain fatty acid biosynthetic process R-HSA-9018678 Biosynthesis of specialized proresolving mediators (SPMs) 50728 negative regulation of inflammatory response R-HSA-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein 6488 dolichol-linked oligosaccharide biosynthetic process R-HSA-196780 Biotin transport and metabolism 6768 biotin metabolic process R-HSA-9033658 Blood group systems biosynthesis 9312 oligosaccharide biosynthetic process R-HSA-70895 Branched-chain amino acid catabolism 9083 branched-chain amino acid catabolic process R-HSA-168302 Budding 19068 virion assembly R-HSA-162588 Budding and maturation of HIV virion 19058 viral life cycle R-HSA-5621481 C-type lectin receptors (CLRs) 2223 stimulatory C-type lectin receptor signaling pathway R-HSA-5218900 CASP8 activity is inhibited 43154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process R-HSA-9662834 CD163 mediating an anti-inflammatory response 2862 negative regulation of inflammatory response to antigenic stimulus R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic 6890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum R-HSA-204005 COPII-mediated vesicle transport 48208 COPII vesicle coating R-HSA-140180 COX reactions 6692 prostanoid metabolic process R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 7268 chemical synaptic transmission R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 7268 chemical synaptic transmission R-HSA-442729 CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde 7268 chemical synaptic transmission R-HSA-2024101 CS/DS degradation 6027 glycosaminoglycan catabolic process R-HSA-1296052 Ca2+ activated K+ channels 1901381 positive regulation of potassium ion transmembrane transport R-HSA-4086398 Ca2+ pathway 7223 Wnt signaling pathway, calcium modulating pathway R-HSA-5576891 Cardiac conduction 61337 cardiac conduction R-HSA-9733709 Cardiogenesis 60914 heart formation R-HSA-200425 Carnitine metabolism 6853 carnitine shuttle R-HSA-71262 Carnitine synthesis 45329 carnitine biosynthetic process R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 97296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway R-HSA-418889 Caspase activation via Dependence Receptors in the absence of ligand 97192 extrinsic apoptotic signaling pathway in absence of ligand R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 97191 extrinsic apoptotic signaling pathway R-HSA-209905 Catecholamine biosynthesis 42423 catecholamine biosynthetic process R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 31145 anaphase-promoting complex-dependent catabolic process R-HSA-1640170 Cell Cycle 7049 cell cycle R-HSA-69620 Cell Cycle Checkpoints 75 cell cycle checkpoint signaling R-HSA-69278 Cell Cycle, Mitotic 278 mitotic cell cycle R-HSA-204998 Cell death signalling via NRAGE, NRIF and NADE 97190 apoptotic signaling pathway R-HSA-446728 Cell junction organization 34329 cell junction assembly R-HSA-9664424 Cell recruitment (pro-inflammatory response) 60326 cell chemotaxis R-HSA-1222541 Cell redox homeostasis 45454 cell redox homeostasis R-HSA-202733 Cell surface interactions at the vascular wall 50900 leukocyte migration R-HSA-421270 Cell-cell junction organization 45216 cell-cell junction organization R-HSA-2559583 Cellular Senescence 90398 cellular senescence R-HSA-189200 Cellular hexose transport 8645 hexose transmembrane transport R-HSA-9711123 Cellular response to chemical stress 62197 cellular response to chemical stress R-HSA-3371556 Cellular response to heat stress 34605 cellular response to heat R-HSA-1234174 Cellular response to hypoxia 71456 cellular response to hypoxia R-HSA-9840373 Cellular response to mitochondrial stress 98780 response to mitochondrial depolarisation R-HSA-9711097 Cellular response to starvation 9267 cellular response to starvation R-HSA-8953897 Cellular responses to stimuli 51716 cellular response to stimulus R-HSA-2262752 Cellular responses to stress 33554 cellular response to stress R-HSA-193681 Ceramide signalling 97190 apoptotic signaling pathway R-HSA-163765 ChREBP activates metabolic gene expression 31325 positive regulation of cellular metabolic process R-HSA-9613829 Chaperone Mediated Autophagy 61684 chaperone-mediated autophagy R-HSA-390466 Chaperonin-mediated protein folding 6457 protein folding R-HSA-191273 Cholesterol biosynthesis 6695 cholesterol biosynthetic process R-HSA-6807047 Cholesterol biosynthesis via desmosterol 33489 cholesterol biosynthetic process via desmosterol R-HSA-6807062 Cholesterol biosynthesis via lathosterol 33490 cholesterol biosynthetic process via lathosterol R-HSA-6798163 Choline catabolism 42426 choline catabolic process R-HSA-2022870 Chondroitin sulfate biosynthesis 30206 chondroitin sulfate biosynthetic process R-HSA-1793185 Chondroitin sulfate/dermatan sulfate metabolism 30204 chondroitin sulfate metabolic process R-HSA-9821002 Chromatin modifications during the maternal to zygotic transition (MZT) 44725 epigenetic programming in the zygotic pronuclei R-HSA-4839726 Chromatin organization 6325 chromatin organization R-HSA-8963888 Chylomicron assembly 34378 chylomicron assembly R-HSA-8964026 Chylomicron clearance 34382 chylomicron remnant clearance R-HSA-8963901 Chylomicron remodeling 34371 chylomicron remodeling R-HSA-5617833 Cilium Assembly 60271 cilium assembly R-HSA-400253 Circadian Clock 7623 circadian rhythm R-HSA-71403 Citric acid cycle (TCA cycle) 6099 tricarboxylic acid cycle R-HSA-373076 Class A/1 (Rhodopsin-like receptors) 7186 G protein-coupled receptor signaling pathway R-HSA-983169 Class I MHC mediated antigen processing & presentation 2474 antigen processing and presentation of peptide antigen via MHC class I R-HSA-9603798 Class I peroxisomal membrane protein import 45046 protein import into peroxisome membrane R-HSA-173623 Classical antibody-mediated complement activation 6958 complement activation, classical pathway R-HSA-9759218 Cobalamin (Cbl) metabolism 9235 cobalamin metabolic process R-HSA-196783 Coenzyme A biosynthesis 15937 coenzyme A biosynthetic process R-HSA-1442490 Collagen degradation 30574 collagen catabolic process R-HSA-1474290 Collagen formation 30199 collagen fibril organization R-HSA-166658 Complement cascade 6956 complement activation R-HSA-6799198 Complex I biogenesis 32981 mitochondrial respiratory chain complex I assembly R-HSA-9865881 Complex III assembly 34551 mitochondrial respiratory chain complex III assembly R-HSA-9864848 Complex IV assembly 33617 mitochondrial cytochrome c oxidase assembly R-HSA-2514853 Condensation of Prometaphase Chromosomes 7076 mitotic chromosome condensation R-HSA-2299718 Condensation of Prophase Chromosomes 7076 mitotic chromosome condensation R-HSA-388841 Costimulation by the CD28 family 31295 T cell costimulation R-HSA-71288 Creatine metabolism 6600 creatine metabolic process R-HSA-8949613 Cristae formation 42407 cristae formation R-HSA-1236973 Cross-presentation of particulate exogenous antigens (phagosomes) 2479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 2479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent R-HSA-2243919 Crosslinking of collagen fibrils 30199 collagen fibril organization R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 45740 positive regulation of DNA replication R-HSA-1614603 Cysteine formation from homocysteine 19346 transsulfuration R-HSA-9707564 Cytoprotection by HMOX1 34599 cellular response to oxidative stress R-HSA-2564830 Cytosolic iron-sulfur cluster assembly 16226 iron-sulfur cluster assembly R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 32481 positive regulation of type I interferon production R-HSA-156584 Cytosolic sulfonation of small molecules 50427 3'-phosphoadenosine 5'-phosphosulfate metabolic process R-HSA-73893 DNA Damage Bypass 19985 translesion synthesis R-HSA-5696394 DNA Damage Recognition in GG-NER 715 nucleotide-excision repair, DNA damage recognition R-HSA-5693532 DNA Double-Strand Break Repair 6302 double-strand break repair R-HSA-73894 DNA Repair 6281 DNA repair R-HSA-69306 DNA Replication 6261 DNA-templated DNA replication R-HSA-5334118 DNA methylation 31507 heterochromatin formation R-HSA-68952 DNA replication initiation 6270 DNA replication initiation R-HSA-69190 DNA strand elongation 6271 DNA strand elongation involved in DNA replication R-HSA-429947 Deadenylation of mRNA 289 nuclear-transcribed mRNA poly(A) tail shortening R-HSA-429914 Deadenylation-dependent mRNA decay 288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay R-HSA-73887 Death Receptor Signaling 7166 cell surface receptor signaling pathway R-HSA-4641257 Degradation of AXIN 90263 positive regulation of canonical Wnt signaling pathway R-HSA-4641258 Degradation of DVL 90090 negative regulation of canonical Wnt signaling pathway R-HSA-916853 Degradation of GABA 9450 gamma-aminobutyric acid catabolic process R-HSA-1614558 Degradation of cysteine and homocysteine 98 sulfur amino acid catabolic process R-HSA-1474228 Degradation of the extracellular matrix 22617 extracellular matrix disassembly R-HSA-606279 Deposition of new CENPA-containing nucleosomes at the centromere 34080 CENP-A containing chromatin assembly R-HSA-73927 Depurination 45007 depurination R-HSA-73928 Depyrimidination 45008 depyrimidination R-HSA-2022923 Dermatan sulfate biosynthesis 30208 dermatan sulfate biosynthetic process R-HSA-3299685 Detoxification of Reactive Oxygen Species 34599 cellular response to oxidative stress R-HSA-5688426 Deubiquitination 16579 protein deubiquitination R-HSA-9725554 Differentiation of keratinocytes in interfollicular epidermis in mammalian skin 3334 keratinocyte development R-HSA-8935690 Digestion 7586 digestion R-HSA-189085 Digestion of dietary carbohydrate 44245 polysaccharide digestion R-HSA-192456 Digestion of dietary lipid 44241 lipid digestion R-HSA-69416 Dimerization of procaspase-8 6919 activation of cysteine-type endopeptidase activity involved in apoptotic process R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 1904886 beta-catenin destruction complex disassembly R-HSA-75205 Dissolution of Fibrin Clot 42730 fibrinolysis R-HSA-212676 Dopamine Neurotransmitter Release Cycle 6836 neurotransmitter transport R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 122 negative regulation of transcription by RNA polymerase II R-HSA-2173788 Downregulation of TGF-beta receptor signaling 30512 negative regulation of transforming growth factor beta receptor signaling pathway R-HSA-9748784 Drug ADME 6805 xenobiotic metabolic process R-HSA-5696400 Dual Incision in GG-NER 6289 nucleotide-excision repair R-HSA-182971 EGFR downregulation 42059 negative regulation of epidermal growth factor receptor signaling pathway R-HSA-212718 EGFR interacts with phospholipase C-gamma 7165 signal transduction R-HSA-9648025 EML4 and NUDC in mitotic spindle formation 7052 mitotic spindle organization R-HSA-2682334 EPH-Ephrin signaling 48013 ephrin receptor signaling pathway R-HSA-901032 ER Quality Control Compartment (ERQC) 1904380 endoplasmic reticulum mannose trimming R-HSA-199977 ER to Golgi Anterograde Transport 6888 endoplasmic reticulum to Golgi vesicle-mediated transport R-HSA-1236974 ER-Phagosome pathway 2479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent R-HSA-6785631 ERBB2 Regulates Cell Motility 2000145 regulation of cell motility R-HSA-211979 Eicosanoids 6690 icosanoid metabolic process R-HSA-2395516 Electron transport from NADPH to Ferredoxin 6124 ferredoxin metabolic process R-HSA-211976 Endogenous sterols 16125 sterol metabolic process R-HSA-917729 Endosomal Sorting Complex Required For Transport (ESCRT) 16197 endosomal transport R-HSA-1236977 Endosomal/Vacuolar pathway 2480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 51726 regulation of cell cycle R-HSA-168275 Entry of Influenza Virion into Host Cell via Endocytosis 19065 receptor-mediated endocytosis of virus by host cell R-HSA-379398 Enzymatic degradation of Dopamine by monoamine oxidase 42420 dopamine catabolic process R-HSA-379397 Enzymatic degradation of dopamine by COMT 42420 dopamine catabolic process R-HSA-212165 Epigenetic regulation of gene expression 40029 epigenetic regulation of gene expression R-HSA-9758919 Epithelial-Mesenchymal Transition (EMT) during gastrulation 1837 epithelial to mesenchymal transition R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 51897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction R-HSA-9027277 Erythropoietin activates Phospholipase C gamma (PLCG) 7202 activation of phospholipase C activity R-HSA-9027284 Erythropoietin activates RAS 46579 positive regulation of Ras protein signal transduction R-HSA-9027283 Erythropoietin activates STAT5 1904894 positive regulation of receptor signaling pathway via STAT R-HSA-2468052 Establishment of Sister Chromatid Cohesion 7062 sister chromatid cohesion R-HSA-193144 Estrogen biosynthesis 6703 estrogen biosynthetic process R-HSA-71384 Ethanol oxidation 6068 ethanol catabolic process R-HSA-156842 Eukaryotic Translation Elongation 6414 translational elongation R-HSA-72613 Eukaryotic Translation Initiation 6413 translational initiation R-HSA-72764 Eukaryotic Translation Termination 6415 translational termination R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 75733 intracellular transport of virus R-HSA-9752946 Expression and translocation of olfactory receptors 10468 regulation of gene expression R-HSA-1474244 Extracellular matrix organization 30198 extracellular matrix organization R-HSA-140834 Extrinsic Pathway of Fibrin Clot Formation 7598 blood coagulation, extrinsic pathway R-HSA-9837092 FASTK family proteins regulate processing and stability of mitochondrial RNAs 44528 regulation of mitochondrial mRNA stability R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 45930 negative regulation of mitotic cell cycle R-HSA-9664323 FCGR3A-mediated IL10 synthesis 2862 negative regulation of inflammatory response to antigenic stimulus R-HSA-9664422 FCGR3A-mediated phagocytosis 38096 Fc-gamma receptor signaling pathway involved in phagocytosis R-HSA-9607240 FLT3 Signaling 19221 cytokine-mediated signaling pathway R-HSA-6783310 Fanconi Anemia Pathway 36297 interstrand cross-link repair R-HSA-75157 FasL/ CD95L signaling 97190 apoptotic signaling pathway R-HSA-8978868 Fatty acid metabolism 6631 fatty acid metabolic process R-HSA-211935 Fatty acids 6631 fatty acid metabolic process R-HSA-75105 Fatty acyl-CoA biosynthesis 46949 fatty-acyl-CoA biosynthetic process R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 38095 Fc-epsilon receptor signaling pathway R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 38096 Fc-gamma receptor signaling pathway involved in phagocytosis R-HSA-1187000 Fertilization 7338 single fertilization R-HSA-390450 Folding of actin by CCT/TriC 51086 chaperone mediated protein folding independent of cofactor R-HSA-163210 Formation of ATP by chemiosmotic coupling 42776 proton motive force-driven mitochondrial ATP synthesis R-HSA-9796292 Formation of axial mesoderm 48320 axial mesoderm formation R-HSA-9823730 Formation of definitive endoderm 1706 endoderm formation R-HSA-9761174 Formation of intermediate mesoderm 48391 intermediate mesoderm formation R-HSA-9758920 Formation of lateral plate mesoderm 48370 lateral mesoderm formation R-HSA-9793380 Formation of paraxial mesoderm 48341 paraxial mesoderm formation R-HSA-2408499 Formation of selenosugars for excretion 1887 selenium compound metabolic process R-HSA-173599 Formation of the active cofactor, UDP-glucuronate 6065 UDP-glucuronate biosynthetic process R-HSA-9823739 Formation of the anterior neural plate 90017 anterior neural plate formation R-HSA-201722 Formation of the beta-catenin:TCF transactivating complex 1904837 beta-catenin-TCF complex assembly R-HSA-6809371 Formation of the cornified envelope 70268 cornification R-HSA-9830364 Formation of the nephric duct 72179 nephric duct formation R-HSA-9832991 Formation of the posterior neural plate 90018 posterior neural plate formation R-HSA-9830674 Formation of the ureteric bud 60676 ureteric bud formation R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 6457 protein folding R-HSA-5661270 Formation of xylulose-5-phosphate 19640 glucuronate catabolic process to xylulose 5-phosphate R-HSA-5652227 Fructose biosynthesis 46370 fructose biosynthetic process R-HSA-70350 Fructose catabolism 61624 fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate R-HSA-5652084 Fructose metabolism 6000 fructose metabolic process R-HSA-168270 Fusion and Uncoating of the Influenza Virion 46718 symbiont entry into host cell R-HSA-168288 Fusion of the Influenza Virion to the Host Cell Endosome 19064 fusion of virus membrane with host plasma membrane R-HSA-69236 G1 Phase 80 mitotic G1 phase R-HSA-69206 G1/S Transition 82 G1/S transition of mitotic cell cycle R-HSA-68911 G2 Phase 7346 regulation of mitotic cell cycle R-HSA-69275 G2/M Transition 86 G2/M transition of mitotic cell cycle R-HSA-888568 GABA synthesis 9449 gamma-aminobutyric acid biosynthetic process R-HSA-6787639 GDP-fucose biosynthesis 42350 GDP-L-fucose biosynthetic process R-HSA-388396 GPCR downstream signalling 7186 G protein-coupled receptor signaling pathway R-HSA-70370 Galactose catabolism 33499 galactose catabolic process via UDP-galactose R-HSA-159854 Gamma-carboxylation, transport, and amino-terminal cleavage of proteins 17187 peptidyl-glutamic acid carboxylation R-HSA-190861 Gap junction assembly 16264 gap junction assembly R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 6297 nucleotide-excision repair, DNA gap filling R-HSA-9758941 Gastrulation 7369 gastrulation R-HSA-211000 Gene Silencing by RNA 31047 regulatory ncRNA-mediated gene silencing R-HSA-74160 Gene expression (Transcription) 6351 DNA-templated transcription R-HSA-212436 Generic Transcription Pathway 60260 regulation of transcription initiation by RNA polymerase II R-HSA-9754189 Germ layer formation at gastrulation 90009 primitive streak formation R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 70911 global genome nucleotide-excision repair R-HSA-163359 Glucagon signaling in metabolic regulation 71377 cellular response to glucagon stimulus R-HSA-194002 Glucocorticoid biosynthesis 6704 glucocorticoid biosynthetic process R-HSA-70263 Gluconeogenesis 6094 gluconeogenesis R-HSA-70326 Glucose metabolism 6006 glucose metabolic process R-HSA-156588 Glucuronidation 52695 cellular glucuronidation R-HSA-210500 Glutamate Neurotransmitter Release Cycle 6836 neurotransmitter transport R-HSA-8964539 Glutamate and glutamine metabolism 9064 glutamine family amino acid metabolic process R-HSA-156590 Glutathione conjugation 1901687 glutathione derivative biosynthetic process R-HSA-174403 Glutathione synthesis and recycling 6750 glutathione biosynthetic process R-HSA-1483206 Glycerophospholipid biosynthesis 46474 glycerophospholipid biosynthetic process R-HSA-6814848 Glycerophospholipid catabolism 46475 glycerophospholipid catabolic process R-HSA-6783984 Glycine degradation 6546 glycine catabolic process R-HSA-70221 Glycogen breakdown (glycogenolysis) 5980 glycogen catabolic process R-HSA-8982491 Glycogen metabolism 5977 glycogen metabolic process R-HSA-3322077 Glycogen synthesis 5978 glycogen biosynthetic process R-HSA-70171 Glycolysis 61621 canonical glycolysis R-HSA-1630316 Glycosaminoglycan metabolism 30203 glycosaminoglycan metabolic process R-HSA-9840309 Glycosphingolipid biosynthesis 6688 glycosphingolipid biosynthetic process R-HSA-9840310 Glycosphingolipid catabolism 46479 glycosphingolipid catabolic process R-HSA-1660662 Glycosphingolipid metabolism 6687 glycosphingolipid metabolic process R-HSA-9845576 Glycosphingolipid transport 35627 ceramide transport R-HSA-389661 Glyoxylate metabolism and glycine degradation 19752 carboxylic acid metabolic process R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 48313 Golgi inheritance R-HSA-982772 Growth hormone receptor signaling 60397 growth hormone receptor signaling pathway via JAK-STAT R-HSA-9609646 HCMV Infection 19058 viral life cycle R-HSA-8963896 HDL assembly 34380 high-density lipoprotein particle assembly R-HSA-8964011 HDL clearance 34384 high-density lipoprotein particle clearance R-HSA-8964058 HDL remodeling 34375 high-density lipoprotein particle remodeling R-HSA-162906 HIV Infection 16032 viral process R-HSA-167169 HIV Transcription Elongation 6368 transcription elongation by RNA polymerase II R-HSA-167161 HIV Transcription Initiation 6367 transcription initiation at RNA polymerase II promoter R-HSA-2022928 HS-GAG biosynthesis 15012 heparan sulfate proteoglycan biosynthetic process R-HSA-2024096 HS-GAG degradation 30200 heparan sulfate proteoglycan catabolic process R-HSA-3371571 HSF1-dependent transactivation 1900034 regulation of cellular response to heat R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand 71383 cellular response to steroid hormone stimulus R-HSA-189451 Heme biosynthesis 6783 heme biosynthetic process R-HSA-189483 Heme degradation 42167 heme catabolic process R-HSA-9707616 Heme signaling 42168 heme metabolic process R-HSA-109582 Hemostasis 7596 blood coagulation R-HSA-70921 Histidine catabolism 6548 histidine catabolic process R-HSA-5693538 Homology Directed Repair 724 double-strand break repair via homologous recombination R-HSA-2142850 Hyaluronan biosynthesis and export 30213 hyaluronan biosynthetic process R-HSA-2142845 Hyaluronan metabolism 30212 hyaluronan metabolic process R-HSA-2160916 Hyaluronan uptake and degradation 30214 hyaluronan catabolic process R-HSA-1483115 Hydrolysis of LPC 6644 phospholipid metabolic process R-HSA-1483152 Hydrolysis of LPE 6644 phospholipid metabolic process R-HSA-204626 Hypusine synthesis from eIF5A-lysine 8612 peptidyl-lysine modification to peptidyl-hypusine R-HSA-1855196 IP3 and IP4 transport between cytosol and nucleus 33271 myo-inositol phosphate transport R-HSA-1855229 IP6 and IP7 transport between cytosol and nucleus 33271 myo-inositol phosphate transport R-HSA-1855215 IPs transport between ER lumen and cytosol 33271 myo-inositol phosphate transport R-HSA-1855156 IPs transport between ER lumen and nucleus 33271 myo-inositol phosphate transport R-HSA-1855184 IPs transport between cytosol and ER lumen 33271 myo-inositol phosphate transport R-HSA-1855192 IPs transport between nucleus and ER lumen 33271 myo-inositol phosphate transport R-HSA-1855170 IPs transport between nucleus and cytosol 33271 myo-inositol phosphate transport R-HSA-937039 IRAK1 recruits IKK complex 43123 positive regulation of canonical NF-kappaB signal transduction R-HSA-381070 IRE1alpha activates chaperones 36498 IRE1-mediated unfolded protein response R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 50776 regulation of immune response R-HSA-2514859 Inactivation, recovery and regulation of the phototransduction cascade 22400 regulation of opsin-mediated signaling pathway R-HSA-400508 Incretin synthesis, secretion, and inactivation 16486 peptide hormone processing R-HSA-9733458 Induction of Cell-Cell Fusion 6948 induction by virus of host cell-cell fusion R-HSA-9635486 Infection with Mycobacterium tuberculosis 51701 biological process involved in interaction with host R-HSA-168255 Influenza Infection 19058 viral life cycle R-HSA-168273 Influenza Viral RNA Transcription and Replication 19083 viral transcription R-HSA-168277 Influenza Virus Induced Apoptosis 6925 inflammatory cell apoptotic process R-HSA-9670095 Inhibition of DNA recombination at telomere 48239 negative regulation of DNA recombination at telomere R-HSA-168315 Inhibition of Host mRNA Processing and RNA Silencing 39524 symbiont-mediated suppression of host mRNA processing R-HSA-168305 Inhibition of Interferon Synthesis 19049 virus-mediated perturbation of host defense response R-HSA-169131 Inhibition of PKR 19049 virus-mediated perturbation of host defense response R-HSA-9635644 Inhibition of membrane repair 44003 modulation by symbiont of host process R-HSA-168249 Innate Immune System 45087 innate immune response R-HSA-1483249 Inositol phosphate metabolism 43647 inositol phosphate metabolic process R-HSA-429593 Inositol transporters 15798 myo-inositol transport R-HSA-9609523 Insertion of tail-anchored proteins into the endoplasmic reticulum membrane 45048 protein insertion into ER membrane R-HSA-163754 Insulin effects increased synthesis of Xylulose-5-Phosphate 5999 xylulose biosynthetic process R-HSA-264876 Insulin processing 30070 insulin processing R-HSA-77387 Insulin receptor recycling 38020 insulin receptor recycling R-HSA-428359 Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA 43488 regulation of mRNA stability R-HSA-163685 Integration of energy metabolism 43467 regulation of generation of precursor metabolites and energy R-HSA-162592 Integration of provirus 75713 establishment of integrated proviral latency R-HSA-2534343 Interaction With Cumulus Cells And The Zona Pellucida 35036 sperm-egg recognition R-HSA-880009 Interconversion of 2-oxoglutarate and 2-hydroxyglutarate 6103 2-oxoglutarate metabolic process R-HSA-499943 Interconversion of nucleotide di- and triphosphates 15949 nucleobase-containing small molecule interconversion R-HSA-351200 Interconversion of polyamines 6596 polyamine biosynthetic process R-HSA-913531 Interferon Signaling 19221 cytokine-mediated signaling pathway R-HSA-909733 Interferon alpha/beta signaling 60337 type I interferon-mediated signaling pathway R-HSA-877300 Interferon gamma signaling 60333 type II interferon-mediated signaling pathway R-HSA-9020702 Interleukin-1 signaling 70498 interleukin-1-mediated signaling pathway R-HSA-447115 Interleukin-12 family signaling 35722 interleukin-12-mediated signaling pathway R-HSA-8983432 Interleukin-15 signaling 35723 interleukin-15-mediated signaling pathway R-HSA-448424 Interleukin-17 signaling 97400 interleukin-17-mediated signaling pathway R-HSA-9012546 Interleukin-18 signaling 35655 interleukin-18-mediated signaling pathway R-HSA-9020558 Interleukin-2 signaling 38110 interleukin-2-mediated signaling pathway R-HSA-9020958 Interleukin-21 signaling 38114 interleukin-21-mediated signaling pathway R-HSA-9020933 Interleukin-23 signaling 38155 interleukin-23-mediated signaling pathway R-HSA-9020956 Interleukin-27 signaling 70106 interleukin-27-mediated signaling pathway R-HSA-9014843 Interleukin-33 signaling 38172 interleukin-33-mediated signaling pathway R-HSA-8984722 Interleukin-35 Signalling 70757 interleukin-35-mediated signaling pathway R-HSA-9008059 Interleukin-37 signaling 71345 cellular response to cytokine stimulus R-HSA-9007892 Interleukin-38 signaling 71345 cellular response to cytokine stimulus R-HSA-1059683 Interleukin-6 signaling 70102 interleukin-6-mediated signaling pathway R-HSA-1266695 Interleukin-7 signaling 38111 interleukin-7-mediated signaling pathway R-HSA-8985947 Interleukin-9 signaling 38113 interleukin-9-mediated signaling pathway R-HSA-8963676 Intestinal absorption 50892 intestinal absorption R-HSA-8981373 Intestinal hexose absorption 106001 intestinal hexose absorption R-HSA-8963678 Intestinal lipid absorption 98856 intestinal lipid absorption R-HSA-434313 Intracellular metabolism of fatty acids regulates insulin secretion 6631 fatty acid metabolic process R-HSA-8981607 Intracellular oxygen transport 15671 oxygen transport R-HSA-5620924 Intraflagellar transport 35735 intraciliary transport involved in cilium assembly R-HSA-109606 Intrinsic Pathway for Apoptosis 97193 intrinsic apoptotic signaling pathway R-HSA-140837 Intrinsic Pathway of Fibrin Clot Formation 7597 blood coagulation, intrinsic pathway R-HSA-983712 Ion channel transport 34220 monoatomic ion transmembrane transport R-HSA-5578775 Ion homeostasis 1903779 regulation of cardiac conduction R-HSA-917937 Iron uptake and transport 6879 intracellular iron ion homeostasis R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 7254 JNK cascade R-HSA-2022854 Keratan sulfate biosynthesis 18146 keratan sulfate biosynthetic process R-HSA-2022857 Keratan sulfate degradation 42340 keratan sulfate catabolic process R-HSA-1638074 Keratan sulfate/keratin metabolism 42339 keratan sulfate metabolic process R-HSA-6805567 Keratinization 31424 keratinization R-HSA-74182 Ketone body metabolism 46950 cellular ketone body metabolic process R-HSA-9830369 Kidney development 1822 kidney development R-HSA-9664420 Killing mechanisms 31343 positive regulation of cell killing R-HSA-983189 Kinesins 7018 microtubule-based movement R-HSA-8964038 LDL clearance 34383 low-density lipoprotein particle clearance R-HSA-8964041 LDL remodeling 34374 low-density lipoprotein particle remodeling R-HSA-9664535 LTC4-CYSLTR mediated IL4 production 2862 negative regulation of inflammatory response to antigenic stimulus R-HSA-5653890 Lactose synthesis 5989 lactose biosynthetic process R-HSA-9615710 Late endosomal microautophagy 61738 late endosomal microautophagy R-HSA-1222499 Latent infection - Other responses of Mtb to phagocytosis 52572 response to host immune response R-HSA-166662 Lectin pathway of complement activation 1867 complement activation, lectin pathway R-HSA-9658195 Leishmania infection 51701 biological process involved in interaction with host R-HSA-9664433 Leishmania parasite growth and survival 31342 negative regulation of cell killing R-HSA-9664417 Leishmania phagocytosis 6909 phagocytosis R-HSA-2046105 Linoleic acid (LA) metabolism 43651 linoleic acid metabolic process R-HSA-8964572 Lipid particle organization 34389 lipid droplet organization R-HSA-9613354 Lipophagy 61724 lipophagy R-HSA-8876384 Listeria monocytogenes entry into host cells 46718 symbiont entry into host cell R-HSA-9620244 Long-term potentiation 7268 chemical synaptic transmission R-HSA-71064 Lysine catabolism 6554 lysine catabolic process R-HSA-8853383 Lysosomal oligosaccharide catabolism 9313 oligosaccharide catabolic process R-HSA-68886 M Phase 87 mitotic M phase R-HSA-450294 MAP kinase activation 51403 stress-activated MAPK cascade R-HSA-2465910 MASTL Facilitates Mitotic Progression 7346 regulation of mitotic cell cycle R-HSA-5657655 MGMT-mediated DNA damage reversal 6307 DNA alkylation repair R-HSA-2132295 MHC class II antigen presentation 19886 antigen processing and presentation of exogenous peptide antigen via MHC class II R-HSA-1632852 Macroautophagy 16236 macroautophagy R-HSA-9856872 Malate-aspartate shuttle 43490 malate-aspartate shuttle R-HSA-9636667 Manipulation of host energy metabolism 44003 modulation by symbiont of host process R-HSA-9816359 Maternal to zygotic transition (MZT) 160021 maternal-to-zygotic transition of gene expression R-HSA-9694631 Maturation of nucleoprotein 19082 viral protein processing R-HSA-9683610 Maturation of nucleoprotein 19082 viral protein processing R-HSA-9694719 Maturation of protein 3a 19082 viral protein processing R-HSA-9683673 Maturation of protein 3a 19082 viral protein processing R-HSA-9694594 Maturation of protein M 19082 viral protein processing R-HSA-9683612 Maturation of protein M 19082 viral protein processing R-HSA-9694548 Maturation of spike protein 19082 viral protein processing R-HSA-9683686 Maturation of spike protein 19082 viral protein processing R-HSA-5662702 Melanin biosynthesis 42438 melanin biosynthetic process R-HSA-199991 Membrane Trafficking 61024 membrane organization R-HSA-174490 Membrane binding and targetting of GAG proteins 75733 intracellular transport of virus R-HSA-1430728 Metabolism 8152 metabolic process R-HSA-2022377 Metabolism of Angiotensinogen to Angiotensins 2003 angiotensin maturation R-HSA-8953854 Metabolism of RNA 16070 RNA metabolic process R-HSA-71291 Metabolism of amino acids and derivatives 1901564 organonitrogen compound metabolic process R-HSA-71387 Metabolism of carbohydrates 5975 carbohydrate metabolic process R-HSA-6806667 Metabolism of fat-soluble vitamins 6775 fat-soluble vitamin metabolic process R-HSA-196757 Metabolism of folate and pterines 46655 folic acid metabolic process R-HSA-2408550 Metabolism of ingested H2SeO4 and H2SeO3 into H2Se 1887 selenium compound metabolic process R-HSA-5263617 Metabolism of ingested MeSeO2H into MeSeH 1887 selenium compound metabolic process R-HSA-2408508 Metabolism of ingested SeMet, Sec, MeSec into H2Se 1887 selenium compound metabolic process R-HSA-556833 Metabolism of lipids 6629 lipid metabolic process R-HSA-202131 Metabolism of nitric oxide: NOS3 activation and regulation 46209 nitric oxide metabolic process R-HSA-15869 Metabolism of nucleotides 55086 nucleobase-containing small molecule metabolic process R-HSA-351202 Metabolism of polyamines 6595 polyamine metabolic process R-HSA-189445 Metabolism of porphyrins 6778 porphyrin-containing compound metabolic process R-HSA-392499 Metabolism of proteins 19538 protein metabolic process R-HSA-380612 Metabolism of serotonin 42429 serotonin catabolic process R-HSA-8957322 Metabolism of steroids 8202 steroid metabolic process R-HSA-6806664 Metabolism of vitamin K 42373 vitamin K metabolic process R-HSA-196849 Metabolism of water-soluble vitamins and cofactors 6767 water-soluble vitamin metabolic process R-HSA-1237112 Methionine salvage pathway 19509 L-methionine salvage from methylthioadenosine R-HSA-156581 Methylation 32259 methylation R-HSA-2408552 Methylation of MeSeH for excretion 1887 selenium compound metabolic process R-HSA-203927 MicroRNA (miRNA) biogenesis 10586 miRNA metabolic process R-HSA-193993 Mineralocorticoid biosynthesis 6705 mineralocorticoid biosynthetic process R-HSA-211958 Miscellaneous substrates 1903604 cytochrome metabolic process R-HSA-5223345 Miscellaneous transport and binding events 55085 transmembrane transport R-HSA-5358508 Mismatch Repair 6298 mismatch repair R-HSA-77289 Mitochondrial Fatty Acid Beta-Oxidation 6635 fatty acid beta-oxidation R-HSA-9836573 Mitochondrial RNA degradation 957 mitochondrial RNA catabolic process R-HSA-166187 Mitochondrial Uncoupling 1990845 adaptive thermogenesis R-HSA-1592230 Mitochondrial biogenesis 7005 mitochondrion organization R-HSA-8949215 Mitochondrial calcium ion transport 6851 mitochondrial calcium ion transmembrane transport R-HSA-1362409 Mitochondrial iron-sulfur cluster biogenesis 16226 iron-sulfur cluster assembly R-HSA-9837999 Mitochondrial protein degradation 35694 mitochondrial protein catabolic process R-HSA-1268020 Mitochondrial protein import 6626 protein targeting to mitochondrion R-HSA-163282 Mitochondrial transcription initiation 6391 transcription initiation at mitochondrial promoter R-HSA-163316 Mitochondrial transcription termination 6393 termination of mitochondrial transcription R-HSA-5368287 Mitochondrial translation 32543 mitochondrial translation R-HSA-5389840 Mitochondrial translation elongation 70125 mitochondrial translational elongation R-HSA-5368286 Mitochondrial translation initiation 70124 mitochondrial translational initiation R-HSA-5419276 Mitochondrial translation termination 70126 mitochondrial translational termination R-HSA-5205647 Mitophagy 423 mitophagy R-HSA-68881 Mitotic Metaphase/Anaphase Transition 7091 metaphase/anaphase transition of mitotic cell cycle R-HSA-68877 Mitotic Prometaphase 236 mitotic prometaphase R-HSA-69618 Mitotic Spindle Checkpoint 7094 mitotic spindle assembly checkpoint signaling R-HSA-68884 Mitotic Telophase/Cytokinesis 281 mitotic cytokinesis R-HSA-9637628 Modulation by Mtb of host immune system 52031 symbiont-mediated perturbation of host defense response R-HSA-947581 Molybdenum cofactor biosynthesis 32324 molybdopterin cofactor biosynthetic process R-HSA-1222449 Mtb iron assimilation by chelation 33214 siderophore-dependent iron import into cell R-HSA-975871 MyD88 cascade initiated on plasma membrane 2755 MyD88-dependent toll-like receptor signaling pathway R-HSA-166166 MyD88-independent TLR4 cascade 2756 MyD88-independent toll-like receptor signaling pathway R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 2755 MyD88-dependent toll-like receptor signaling pathway R-HSA-525793 Myogenesis 51149 positive regulation of muscle cell differentiation R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 6457 protein folding R-HSA-205025 NADE modulates death signalling 43281 regulation of cysteine-type endopeptidase activity involved in apoptotic process R-HSA-389542 NADPH regeneration 6740 NADPH regeneration R-HSA-167060 NGF processing 32455 nerve growth factor processing R-HSA-187024 NGF-independant TRKA activation 7190 activation of adenylate cyclase activity R-HSA-5676590 NIK-->noncanonical NF-kB signaling 38061 non-canonical NF-kappaB signal transduction R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 7221 positive regulation of transcription of Notch receptor target R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 6355 regulation of DNA-templated transcription R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 30522 intracellular receptor signaling pathway R-HSA-193648 NRAGE signals death through JNK 43065 positive regulation of apoptotic process R-HSA-205043 NRIF signals cell death from the nucleus 43065 positive regulation of apoptotic process R-HSA-168276 NS1 Mediated Effects on Host Pathways 19054 modulation by virus of host cellular process R-HSA-9025046 NTF3 activates NTRK2 (TRKB) signaling 51388 positive regulation of neurotrophin TRK receptor signaling pathway R-HSA-9034013 NTF3 activates NTRK3 signaling 51388 positive regulation of neurotrophin TRK receptor signaling pathway R-HSA-9026357 NTF4 activates NTRK2 (TRKB) signaling 51388 positive regulation of neurotrophin TRK receptor signaling pathway R-HSA-9603505 NTRK3 as a dependence receptor 2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand R-HSA-164944 Nef and signal transduction 19049 virus-mediated perturbation of host defense response R-HSA-164938 Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 19049 virus-mediated perturbation of host defense response R-HSA-5250941 Negative epigenetic regulation of rRNA expression 45814 negative regulation of gene expression, epigenetic R-HSA-9604323 Negative regulation of NOTCH4 signaling 45746 negative regulation of Notch signaling pathway R-HSA-3772470 Negative regulation of TCF-dependent signaling by WNT ligand antagonists 90090 negative regulation of canonical Wnt signaling pathway R-HSA-8866904 Negative regulation of activity of TFAP2 (AP-2) family transcription factors 122 negative regulation of transcription by RNA polymerase II R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 32480 negative regulation of type I interferon production R-HSA-9831926 Nephron development 72210 metanephric nephron development R-HSA-9675108 Nervous system development 7399 nervous system development R-HSA-112316 Neuronal System 7268 chemical synaptic transmission R-HSA-112310 Neurotransmitter release cycle 7269 neurotransmitter secretion R-HSA-112313 Neurotransmitter uptake and metabolism In glial cells 1504 neurotransmitter uptake R-HSA-6798695 Neutrophil degranulation 43312 neutrophil degranulation R-HSA-197264 Nicotinamide salvaging 34356 NAD biosynthesis via nicotinamide riboside salvage pathway R-HSA-196807 Nicotinate metabolism 19674 NAD metabolic process R-HSA-427413 NoRC negatively regulates rRNA expression 183 rDNA heterochromatin formation R-HSA-5693571 Nonhomologous End-Joining (NHEJ) 6303 double-strand break repair via nonhomologous end joining R-HSA-927802 Nonsense-Mediated Decay (NMD) 184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay R-HSA-181430 Norepinephrine Neurotransmitter Release Cycle 6836 neurotransmitter transport R-HSA-350054 Notch-HLH transcription pathway 6367 transcription initiation at RNA polymerase II promoter R-HSA-2995410 Nuclear Envelope (NE) Reassembly 7084 mitotic nuclear membrane reassembly R-HSA-2980766 Nuclear Envelope Breakdown 7077 mitotic nuclear membrane disassembly R-HSA-383280 Nuclear Receptor transcription pathway 6367 transcription initiation at RNA polymerase II promoter R-HSA-774815 Nucleosome assembly 6334 nucleosome assembly R-HSA-5696398 Nucleotide Excision Repair 6289 nucleotide-excision repair R-HSA-8956320 Nucleotide biosynthesis 34404 nucleobase-containing small molecule biosynthetic process R-HSA-8956319 Nucleotide catabolism 34656 nucleobase-containing small molecule catabolic process R-HSA-8956321 Nucleotide salvage 43173 nucleotide salvage R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 35872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway R-HSA-5173214 O-glycosylation of TSR domain-containing proteins 36066 protein O-linked fucosylation R-HSA-5173105 O-linked glycosylation 6493 protein O-linked glycosylation R-HSA-913709 O-linked glycosylation of mucins 16266 O-glycan processing R-HSA-1480926 O2/CO2 exchange in erythrocytes 15701 bicarbonate transport R-HSA-8983711 OAS antiviral response 51607 defense response to virus R-HSA-9853506 OGDH complex synthesizes succinyl-CoA from 2-OG 1901290 succinyl-CoA biosynthetic process R-HSA-1852241 Organelle biogenesis and maintenance 6996 organelle organization R-HSA-4086400 PCP/CE pathway 60071 Wnt signaling pathway, planar cell polarity pathway R-HSA-9861559 PDH complex synthesizes acetyl-CoA from PYR 6086 acetyl-CoA biosynthetic process from pyruvate R-HSA-381042 PERK regulates gene expression 36499 PERK-mediated unfolded protein response R-HSA-1483196 PI and PC transport between ER and Golgi membranes 15914 phospholipid transport R-HSA-198203 PI3K/AKT activation 43491 phosphatidylinositol 3-kinase/protein kinase B signal transduction R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 51896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction R-HSA-5205685 PINK1-PRKN Mediated Mitophagy 16236 macroautophagy R-HSA-1257604 PIP3 activates AKT signaling 51897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction R-HSA-1660510 PIPs transport between Golgi and plasma membranes 45332 phospholipid translocation R-HSA-1660502 PIPs transport between early and late endosome membranes 45332 phospholipid translocation R-HSA-1660537 PIPs transport between early endosome and Golgi membranes 45332 phospholipid translocation R-HSA-1660508 PIPs transport between late endosome and Golgi membranes 45332 phospholipid translocation R-HSA-1660524 PIPs transport between plasma and early endosome membranes 45332 phospholipid translocation R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 34587 piRNA processing R-HSA-163615 PKA activation 34199 activation of protein kinase A activity R-HSA-163358 PKA-mediated phosphorylation of key metabolic factors 10737 protein kinase A signaling R-HSA-9833482 PKR-mediated signaling 39585 PKR/eIFalpha signaling R-HSA-167021 PLC-gamma1 signalling 7202 activation of phospholipase C activity R-HSA-163767 PP2A-mediated dephosphorylation of key metabolic factors 10468 regulation of gene expression R-HSA-1989781 PPARA activates gene expression 19222 regulation of metabolic process R-HSA-212300 PRC2 methylates histones and DNA 45814 negative regulation of gene expression, epigenetic R-HSA-8849474 PTK6 Activates STAT3 46427 positive regulation of receptor signaling pathway via JAK-STAT R-HSA-8849472 PTK6 Down-Regulation 9968 negative regulation of signal transduction R-HSA-8849470 PTK6 Regulates Cell Cycle 45787 positive regulation of cell cycle R-HSA-8849469 PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 45742 positive regulation of epidermal growth factor receptor signaling pathway R-HSA-168303 Packaging of Eight RNA Segments 19072 viral genome packaging R-HSA-9664407 Parasite infection 75001 adhesion of symbiont infection structure to host R-HSA-9824443 Parasitic Infection Pathways 44419 biological process involved in interspecies interaction between organisms R-HSA-71336 Pentose phosphate pathway 6098 pentose-phosphate shunt R-HSA-209952 Peptide hormone biosynthesis 16486 peptide hormone processing R-HSA-2980736 Peptide hormone metabolism 6518 peptide metabolic process R-HSA-390918 Peroxisomal lipid metabolism 9062 fatty acid catabolic process R-HSA-9664873 Pexophagy 425 pexophagy R-HSA-9637698 Phagocyte cell death caused by cytosolic Mtb 1907 symbiont-mediated killing of host cell R-HSA-8963691 Phenylalanine and tyrosine metabolism 9072 aromatic amino acid metabolic process R-HSA-8964208 Phenylalanine metabolism 6558 L-phenylalanine metabolic process R-HSA-2393930 Phosphate bond hydrolysis by NUDT proteins 55086 nucleobase-containing small molecule metabolic process R-HSA-1483257 Phospholipid metabolism 6644 phospholipid metabolic process R-HSA-176412 Phosphorylation of the APC/C 1901990 regulation of mitotic cell cycle phase transition R-HSA-5578768 Physiological factors 1903779 regulation of cardiac conduction R-HSA-8963898 Plasma lipoprotein assembly 34377 plasma lipoprotein particle assembly R-HSA-174824 Plasma lipoprotein assembly, remodeling, and clearance 71827 plasma lipoprotein particle organization R-HSA-8964043 Plasma lipoprotein clearance 34381 plasma lipoprotein particle clearance R-HSA-8963899 Plasma lipoprotein remodeling 34369 plasma lipoprotein particle remodeling R-HSA-75896 Plasmalogen biosynthesis 8611 ether lipid biosynthetic process R-HSA-76002 Platelet activation, signaling and aggregation 30168 platelet activation R-HSA-114608 Platelet degranulation 2576 platelet degranulation R-HSA-156711 Polo-like kinase mediated events 51726 regulation of cell cycle R-HSA-5250913 Positive epigenetic regulation of rRNA expression 45815 transcription initiation-coupled chromatin remodeling R-HSA-389977 Post-chaperonin tubulin folding pathway 7023 post-chaperonin tubulin folding pathway R-HSA-426496 Post-transcriptional silencing by small RNAs 35194 regulatory ncRNA-mediated post-transcriptional gene silencing R-HSA-163125 Post-translational modification: synthesis of GPI-anchored proteins 6501 C-terminal protein lipidation R-HSA-597592 Post-translational protein modification 43687 post-translational protein modification R-HSA-1296071 Potassium Channels 71805 potassium ion transmembrane transport R-HSA-196108 Pregnenolone biosynthesis 6700 C21-steroid hormone biosynthetic process R-HSA-112308 Presynaptic depolarization and calcium channel opening 51899 membrane depolarization R-HSA-75067 Processing of Capped Intronless Pre-mRNA 31124 mRNA 3'-end processing R-HSA-5357801 Programmed Cell Death 12501 programmed cell death R-HSA-964827 Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 1904381 Golgi apparatus mannose trimming R-HSA-70688 Proline catabolism 6562 proline catabolic process R-HSA-169893 Prolonged ERK activation events 165 MAPK cascade R-HSA-71032 Propionyl-CoA catabolism 19626 short-chain fatty acid catabolic process R-HSA-391251 Protein folding 51084 'de novo' post-translational protein folding R-HSA-9629569 Protein hydroxylation 18126 protein hydroxylation R-HSA-9857492 Protein lipoylation 9249 protein lipoylation R-HSA-9609507 Protein localization 8104 protein localization R-HSA-8876725 Protein methylation 6479 protein methylation R-HSA-5676934 Protein repair 30091 protein repair R-HSA-8852135 Protein ubiquitination 16567 protein ubiquitination R-HSA-74259 Purine catabolism 6195 purine nucleotide catabolic process R-HSA-73817 Purine ribonucleoside monophosphate biosynthesis 9168 purine ribonucleoside monophosphate biosynthetic process R-HSA-74217 Purine salvage 43101 purine-containing compound salvage R-HSA-9660826 Purinergic signaling in leishmaniasis infection 35590 purinergic nucleotide receptor signaling pathway R-HSA-500753 Pyrimidine biosynthesis 46134 pyrimidine nucleoside biosynthetic process R-HSA-73621 Pyrimidine catabolism 46135 pyrimidine nucleoside catabolic process R-HSA-73614 Pyrimidine salvage 43097 pyrimidine nucleoside salvage R-HSA-71737 Pyrophosphate hydrolysis 71344 diphosphate metabolic process R-HSA-5620971 Pyroptosis 70269 pyroptosis R-HSA-70268 Pyruvate metabolism 6090 pyruvate metabolic process R-HSA-112409 RAF-independent MAPK1/3 activation 70371 ERK1 and ERK2 cascade R-HSA-5673001 RAF/MAP kinase cascade 165 MAPK cascade R-HSA-9012999 RHO GTPase cycle 51056 regulation of small GTPase mediated signal transduction R-HSA-5213460 RIPK1-mediated regulated necrosis 70266 necroptotic process R-HSA-73854 RNA Polymerase I Promoter Clearance 6361 transcription initiation at RNA polymerase I promoter R-HSA-73864 RNA Polymerase I Transcription 6360 transcription by RNA polymerase I R-HSA-73863 RNA Polymerase I Transcription Termination 6363 termination of RNA polymerase I transcription R-HSA-73776 RNA Polymerase II Promoter Escape 6368 transcription elongation by RNA polymerase II R-HSA-73857 RNA Polymerase II Transcription 6366 transcription by RNA polymerase II R-HSA-75955 RNA Polymerase II Transcription Elongation 6368 transcription elongation by RNA polymerase II R-HSA-75953 RNA Polymerase II Transcription Initiation 6367 transcription initiation at RNA polymerase II promoter R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 6367 transcription initiation at RNA polymerase II promoter R-HSA-73856 RNA Polymerase II Transcription Termination 6369 termination of RNA polymerase II transcription R-HSA-73780 RNA Polymerase III Chain Elongation 6385 transcription elongation by RNA polymerase III R-HSA-74158 RNA Polymerase III Transcription 6383 transcription by RNA polymerase III R-HSA-73980 RNA Polymerase III Transcription Termination 6386 termination of RNA polymerase III transcription R-HSA-6807505 RNA polymerase II transcribes snRNA genes 42795 snRNA transcription by RNA polymerase II R-HSA-1222556 ROS and RNS production in phagocytes 45454 cell redox homeostasis R-HSA-9833110 RSV-host interactions 19054 modulation by virus of host cellular process R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 45589 regulation of regulatory T cell differentiation R-HSA-8931987 RUNX1 regulates estrogen receptor mediated transcription 33146 regulation of intracellular estrogen receptor signaling pathway R-HSA-8935964 RUNX1 regulates expression of components of tight junctions 2000810 regulation of bicellular tight junction assembly R-HSA-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function 45652 regulation of megakaryocyte differentiation R-HSA-8939245 RUNX1 regulates transcription of genes involved in BCR signaling 50855 regulation of B cell receptor signaling pathway R-HSA-8939256 RUNX1 regulates transcription of genes involved in WNT signaling 30111 regulation of Wnt signaling pathway R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 1902036 regulation of hematopoietic stem cell differentiation R-HSA-8939242 RUNX1 regulates transcription of genes involved in differentiation of keratinocytes 45616 regulation of keratinocyte differentiation R-HSA-8939246 RUNX1 regulates transcription of genes involved in differentiation of myeloid cells 45637 regulation of myeloid cell differentiation R-HSA-8939247 RUNX1 regulates transcription of genes involved in interleukin signaling 1959 regulation of cytokine-mediated signaling pathway R-HSA-8934903 Receptor Mediated Mitophagy 16236 macroautophagy R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 1904333 positive regulation of error-prone translesion synthesis R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 60236 regulation of mitotic spindle organization R-HSA-159418 Recycling of bile acids and salts 15721 bile acid and bile salt transport R-HSA-5218859 Regulated Necrosis 97300 programmed necrotic cell death R-HSA-193692 Regulated proteolysis of p75NTR 31293 membrane protein intracellular domain proteolysis R-HSA-3371378 Regulation by c-FLIP 1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 1905784 regulation of anaphase-promoting complex-dependent catabolic process R-HSA-169911 Regulation of Apoptosis 42981 regulation of apoptotic process R-HSA-9708530 Regulation of BACH1 activity 51090 regulation of DNA-binding transcription factor activity R-HSA-9762293 Regulation of CDH11 gene transcription 6355 regulation of DNA-templated transcription R-HSA-9759811 Regulation of CDH11 mRNA translation by microRNAs 35195 miRNA-mediated post-transcriptional gene silencing R-HSA-977606 Regulation of Complement cascade 30449 regulation of complement activation R-HSA-9764260 Regulation of Expression and Function of Type II Classical Cadherins 2000047 regulation of cell-cell adhesion mediated by cadherin R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 6110 regulation of glycolytic process R-HSA-3371453 Regulation of HSF1-mediated heat shock response 1900034 regulation of cellular response to heat R-HSA-9759476 Regulation of Homotypic Cell-Cell Adhesion 34110 regulation of homotypic cell-cell adhesion R-HSA-912694 Regulation of IFNA/IFNB signaling 60338 regulation of type I interferon-mediated signaling pathway R-HSA-877312 Regulation of IFNG signaling 60334 regulation of type II interferon-mediated signaling pathway R-HSA-211728 Regulation of PAK-2p34 activity by PS-GAP/RHG10 43066 negative regulation of apoptotic process R-HSA-5357905 Regulation of TNFR1 signaling 10803 regulation of tumor necrosis factor-mediated signaling pathway R-HSA-5633007 Regulation of TP53 Activity 1901796 regulation of signal transduction by p53 class mediator R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 43066 negative regulation of apoptotic process R-HSA-186712 Regulation of beta-cell development 31018 endocrine pancreas development R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 45540 regulation of cholesterol biosynthetic process R-HSA-9842860 Regulation of endogenous retroelements 141005 retrotransposon silencing by heterochromatin formation R-HSA-9845323 Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) 141006 piRNA-mediated retrotransposon silencing by heterochromatin formation R-HSA-9634600 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 1904538 regulation of glycolytic process through fructose-6-phosphate R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 32479 regulation of type I interferon production R-HSA-422356 Regulation of insulin secretion 50796 regulation of insulin secretion R-HSA-400206 Regulation of lipid metabolism by PPARalpha 19216 regulation of lipid metabolic process R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 43488 regulation of mRNA stability R-HSA-5675482 Regulation of necroptotic cell death 60544 regulation of necroptotic process R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 6521 regulation of cellular amino acid metabolic process R-HSA-204174 Regulation of pyruvate dehydrogenase (PDH) complex 10510 regulation of acetyl-CoA biosynthetic process from pyruvate R-HSA-9861718 Regulation of pyruvate metabolism 62012 regulation of small molecule metabolic process R-HSA-350864 Regulation of thyroid hormone activity 42403 thyroid hormone metabolic process R-HSA-168298 Release 19076 viral release from host cell R-HSA-159782 Removal of aminoterminal propeptides from gamma-carboxylated proteins 6465 signal peptide processing R-HSA-9821993 Replacement of protamines by nucleosomes in the male pronucleus 44725 epigenetic programming in the zygotic pronuclei R-HSA-1474165 Reproduction 48609 multicellular organismal reproductive process R-HSA-73933 Resolution of Abasic Sites (AP sites) 6287 base-excision repair, gap-filling R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 45003 double-strand break repair via synthesis-dependent strand annealing R-HSA-2500257 Resolution of Sister Chromatid Cohesion 70 mitotic sister chromatid segregation R-HSA-611105 Respiratory electron transport 22904 respiratory electron transport chain R-HSA-9648895 Response of EIF2AK1 (HRI) to heme deficiency 10999 regulation of eIF2 alpha phosphorylation by heme R-HSA-9633012 Response of EIF2AK4 (GCN2) to amino acid deficiency 34198 cellular response to amino acid starvation R-HSA-9637690 Response of Mtb to phagocytosis 52031 symbiont-mediated perturbation of host defense response R-HSA-5660526 Response to metal ions 10038 response to metal ion R-HSA-975634 Retinoid metabolism and transport 1523 retinoid metabolic process R-HSA-888593 Reuptake of GABA 51936 gamma-aminobutyric acid reuptake R-HSA-73943 Reversal of alkylation damage by DNA dioxygenases 6307 DNA alkylation repair R-HSA-162589 Reverse Transcription of HIV RNA 6278 RNA-templated DNA biosynthetic process R-HSA-1475029 Reversible hydration of carbon dioxide 15701 bicarbonate transport R-HSA-9037628 Rhesus blood group biosynthesis 43043 peptide biosynthetic process R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 1901990 regulation of mitotic cell cycle phase transition R-HSA-427359 SIRT1 negatively regulates rRNA expression 183 rDNA heterochromatin formation R-HSA-77588 SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 6398 mRNA 3'-end processing by stem-loop binding and cleavage R-HSA-111367 SLBP independent Processing of Histone Pre-mRNAs 16071 mRNA metabolic process R-HSA-425407 SLC-mediated transmembrane transport 55085 transmembrane transport R-HSA-9860276 SLC15A4:TASL-dependent IRF5 activation 34121 regulation of toll-like receptor signaling pathway R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 45944 positive regulation of transcription by RNA polymerase II R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 6614 SRP-dependent cotranslational protein targeting to membrane R-HSA-9645135 STAT5 Activation 34097 response to cytokine R-HSA-2990846 SUMOylation 16925 protein sumoylation R-HSA-2408522 Selenoamino acid metabolism 16259 selenocysteine metabolic process R-HSA-9709957 Sensory Perception 7600 sensory perception R-HSA-9717189 Sensory perception of taste 50909 sensory perception of taste R-HSA-9659379 Sensory processing of sound 7605 sensory perception of sound R-HSA-2467813 Separation of Sister Chromatids 51306 mitotic sister chromatid separation R-HSA-977347 Serine biosynthesis 6564 L-serine biosynthetic process R-HSA-181429 Serotonin Neurotransmitter Release Cycle 6836 neurotransmitter transport R-HSA-209931 Serotonin and melatonin biosynthesis 46219 indolalkylamine biosynthetic process R-HSA-201451 Signaling by BMP 30509 BMP signaling pathway R-HSA-9680350 Signaling by CSF1 (M-CSF) in myeloid cells 19221 cytokine-mediated signaling pathway R-HSA-9674555 Signaling by CSF3 (G-CSF) 19221 cytokine-mediated signaling pathway R-HSA-177929 Signaling by EGFR 7173 epidermal growth factor receptor signaling pathway R-HSA-1227986 Signaling by ERBB2 38128 ERBB2 signaling pathway R-HSA-9006335 Signaling by Erythropoietin 38162 erythropoietin-mediated signaling pathway R-HSA-190236 Signaling by FGFR 8543 fibroblast growth factor receptor signaling pathway R-HSA-2028269 Signaling by Hippo 35329 hippo signaling R-HSA-74752 Signaling by Insulin receptor 8286 insulin receptor signaling pathway R-HSA-449147 Signaling by Interleukins 19221 cytokine-mediated signaling pathway R-HSA-8852405 Signaling by MST1 48012 hepatocyte growth factor receptor signaling pathway R-HSA-157118 Signaling by NOTCH 7219 Notch signaling pathway R-HSA-166520 Signaling by NTRKs 48011 neurotrophin TRK receptor signaling pathway R-HSA-194315 Signaling by Rho GTPases 7264 small GTPase-mediated signal transduction R-HSA-170834 Signaling by TGF-beta Receptor Complex 7179 transforming growth factor beta receptor signaling pathway R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 48009 insulin-like growth factor receptor signaling pathway R-HSA-194138 Signaling by VEGF 48010 vascular endothelial growth factor receptor signaling pathway R-HSA-195721 Signaling by WNT 16055 Wnt signaling pathway R-HSA-167044 Signalling to RAS 7265 Ras protein signal transduction R-HSA-187706 Signalling to p38 via RIT and RIN 7264 small GTPase-mediated signal transduction R-HSA-426486 Small interfering RNA (siRNA) biogenesis 30422 siRNA processing R-HSA-445355 Smooth Muscle Contraction 6936 muscle contraction R-HSA-9824272 Somitogenesis 1756 somitogenesis R-HSA-9827857 Specification of primordial germ cells 7281 germ cell development R-HSA-9834899 Specification of the neural plate border 60896 neural plate pattern specification R-HSA-1300642 Sperm Motility And Taxes 35036 sperm-egg recognition R-HSA-9845614 Sphingolipid catabolism 30149 sphingolipid catabolic process R-HSA-1660661 Sphingolipid de novo biosynthesis 30148 sphingolipid biosynthetic process R-HSA-428157 Sphingolipid metabolism 6665 sphingolipid metabolic process R-HSA-390522 Striated Muscle Contraction 30049 muscle filament sliding R-HSA-1614517 Sulfide oxidation to sulfate 70221 sulfide oxidation, using sulfide:quinone oxidoreductase R-HSA-1614635 Sulfur amino acid metabolism 96 sulfur amino acid metabolic process R-HSA-9635465 Suppression of apoptosis 33668 symbiont-mediated suppression of host apoptosis R-HSA-9636569 Suppression of autophagy 34054 symbiont-mediated suppression of host defense-related programmed cell death R-HSA-9637687 Suppression of phagosomal maturation 52170 symbiont-mediated suppression of host innate immune response R-HSA-174495 Synthesis And Processing Of GAG, GAGPOL Polyproteins 19082 viral protein processing R-HSA-171286 Synthesis and processing of ENV and VPU 19082 viral protein processing R-HSA-2142816 Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) 97267 omega-hydroxylase P450 pathway R-HSA-2142712 Synthesis of 12-eicosatetraenoic acid derivatives 19372 lipoxygenase pathway R-HSA-2142770 Synthesis of 15-eicosatetraenoic acid derivatives 19372 lipoxygenase pathway R-HSA-2142688 Synthesis of 5-eicosatetraenoic acids 19372 lipoxygenase pathway R-HSA-1483171 Synthesis of BMP 2001312 lysobisphosphatidic acid biosynthetic process R-HSA-1483076 Synthesis of CL 32049 cardiolipin biosynthetic process R-HSA-69239 Synthesis of DNA 6260 DNA replication R-HSA-446199 Synthesis of Dolichyl-phosphate 6489 dolichyl diphosphate biosynthetic process R-HSA-446205 Synthesis of GDP-mannose 9298 GDP-mannose biosynthetic process R-HSA-2142696 Synthesis of Hepoxilins (HX) and Trioxilins (TrX) 51121 hepoxilin metabolic process R-HSA-77111 Synthesis of Ketone Bodies 46951 ketone body biosynthetic process R-HSA-2142691 Synthesis of Leukotrienes (LT) and Eoxins (EX) 6691 leukotriene metabolic process R-HSA-2142700 Synthesis of Lipoxins (LX) 2001301 lipoxin biosynthetic process R-HSA-1483166 Synthesis of PA 6654 phosphatidic acid biosynthetic process R-HSA-1483191 Synthesis of PC 6656 phosphatidylcholine biosynthetic process R-HSA-1483213 Synthesis of PE 6646 phosphatidylethanolamine biosynthetic process R-HSA-1483148 Synthesis of PG 6655 phosphatidylglycerol biosynthetic process R-HSA-1483226 Synthesis of PI 6661 phosphatidylinositol biosynthetic process R-HSA-1483248 Synthesis of PIPs at the ER membrane 6661 phosphatidylinositol biosynthetic process R-HSA-1660514 Synthesis of PIPs at the Golgi membrane 6661 phosphatidylinositol biosynthetic process R-HSA-1660516 Synthesis of PIPs at the early endosome membrane 6661 phosphatidylinositol biosynthetic process R-HSA-1660517 Synthesis of PIPs at the late endosome membrane 6661 phosphatidylinositol biosynthetic process R-HSA-1660499 Synthesis of PIPs at the plasma membrane 6661 phosphatidylinositol biosynthetic process R-HSA-1483101 Synthesis of PS 6659 phosphatidylserine biosynthetic process R-HSA-2162123 Synthesis of Prostaglandins (PG) and Thromboxanes (TX) 19371 cyclooxygenase pathway R-HSA-446210 Synthesis of UDP-N-acetyl-glucosamine 6048 UDP-N-acetylglucosamine biosynthetic process R-HSA-192105 Synthesis of bile acids and bile salts 6699 bile acid biosynthetic process R-HSA-5358493 Synthesis of diphthamide-EEF2 17183 protein histidyl modification to diphthamide R-HSA-162699 Synthesis of dolichyl-phosphate mannose 18279 protein N-linked glycosylation via asparagine R-HSA-480985 Synthesis of dolichyl-phosphate-glucose 18279 protein N-linked glycosylation via asparagine R-HSA-2142670 Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) 19373 epoxygenase P450 pathway R-HSA-162710 Synthesis of glycosylphosphatidylinositol (GPI) 16254 preassembly of GPI anchor in ER membrane R-HSA-75876 Synthesis of very long-chain fatty acyl-CoAs 35338 long-chain fatty-acyl-CoA biosynthetic process R-HSA-422085 Synthesis, secretion, and deacylation of Ghrelin 16486 peptide hormone processing R-HSA-381771 Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) 120116 glucagon processing R-HSA-202403 TCR signaling 50852 T cell receptor signaling pathway R-HSA-5221030 TET1,2,3 and TDG demethylate DNA 141167 chromosomal 5-methylcytosine DNA demethylation, oxidation pathway R-HSA-8866906 TFAP2 (AP-2) family regulates transcription of other transcription factors 45944 positive regulation of transcription by RNA polymerase II R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 2756 MyD88-independent toll-like receptor signaling pathway R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 7249 canonical NF-kappaB signal transduction R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 35666 TRIF-dependent toll-like receptor signaling pathway R-HSA-75893 TNF signaling 33209 tumor necrosis factor-mediated signaling pathway R-HSA-5357956 TNFR1-induced NF-kappa-B signaling pathway 7249 canonical NF-kappaB signal transduction R-HSA-5357786 TNFR1-induced proapoptotic signaling 71550 death-inducing signaling complex assembly R-HSA-5626978 TNFR1-mediated ceramide production 2000304 positive regulation of ceramide biosynthetic process R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 33209 tumor necrosis factor-mediated signaling pathway R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 6977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 42981 regulation of apoptotic process R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 7249 canonical NF-kappaB signal transduction R-HSA-937061 TRIF (TICAM1)-mediated TLR4 signaling 35666 TRIF-dependent toll-like receptor signaling pathway R-HSA-187042 TRKA activation by NGF 48011 neurotrophin TRK receptor signaling pathway R-HSA-3295583 TRP channels 70588 calcium ion transmembrane transport R-HSA-9033500 TYSND1 cleaves peroxisomal proteins 16485 protein processing R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 50434 positive regulation of viral transcription R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 32201 telomere maintenance via semi-conservative replication R-HSA-171319 Telomere Extension By Telomerase 7004 telomere maintenance via telomerase R-HSA-157579 Telomere Maintenance 723 telomere maintenance R-HSA-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation 46146 tetrahydrobiopterin metabolic process R-HSA-2453902 The canonical retinoid cycle in rods (twilight vision) 1523 retinoid metabolic process R-HSA-167826 The fatty acid cycling model 1902600 proton transmembrane transport R-HSA-2514856 The phototransduction cascade 16056 rhodopsin mediated signaling pathway R-HSA-2187335 The retinoid cycle in cones (daylight vision) 1523 retinoid metabolic process R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 1902749 regulation of cell cycle G2/M phase transition R-HSA-8849175 Threonine catabolism 19518 L-threonine catabolic process to glycine R-HSA-209968 Thyroxine biosynthesis 6590 thyroid hormone generation R-HSA-420029 Tight junction interactions 70830 bicellular tight junction assembly R-HSA-1222538 Tolerance by Mtb to nitric oxide produced by macrophages 141082 symbiont-mediated detoxification of host-generated reactive oxygen species R-HSA-1222387 Tolerance of reactive oxygen produced by macrophages 52164 symbiont defense to host-produced reactive oxygen species R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 34166 toll-like receptor 10 signaling pathway R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 34134 toll-like receptor 2 signaling pathway R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 34138 toll-like receptor 3 signaling pathway R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 34142 toll-like receptor 4 signaling pathway R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 34146 toll-like receptor 5 signaling pathway R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 34162 toll-like receptor 9 signaling pathway R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 38123 toll-like receptor TLR1:TLR2 signaling pathway R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 38124 toll-like receptor TLR6:TLR2 signaling pathway R-HSA-168898 Toll-like Receptor Cascades 2224 toll-like receptor signaling pathway R-HSA-75944 Transcription from mitochondrial promoters 6390 mitochondrial transcription R-HSA-167172 Transcription of the HIV genome 19083 viral transcription R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 6283 transcription-coupled nucleotide-excision repair R-HSA-8953750 Transcriptional Regulation by E2F6 70317 negative regulation of G0 to G1 transition R-HSA-8986944 Transcriptional Regulation by MECP2 40029 epigenetic regulation of gene expression R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 6351 DNA-templated transcription R-HSA-5578749 Transcriptional regulation by small RNAs 60964 regulation of miRNA-mediated gene silencing R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 6357 regulation of transcription by RNA polymerase II R-HSA-9843743 Transcriptional regulation of brown and beige adipocyte differentiation 90335 regulation of brown fat cell differentiation R-HSA-9616222 Transcriptional regulation of granulopoiesis 30851 granulocyte differentiation R-HSA-452723 Transcriptional regulation of pluripotent stem cells 35019 somatic stem cell population maintenance R-HSA-9690406 Transcriptional regulation of testis differentiation 8584 male gonad development R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 50872 white fat cell differentiation R-HSA-917977 Transferrin endocytosis and recycling 33572 transferrin transport R-HSA-72766 Translation 6412 translation R-HSA-9727281 Translation of Accessory Proteins 19081 viral translation R-HSA-9694635 Translation of Structural Proteins 19081 viral translation R-HSA-9683701 Translation of Structural Proteins 19081 viral translation R-HSA-110320 Translesion Synthesis by POLH 70987 error-free translesion synthesis R-HSA-5656121 Translesion synthesis by POLI 42276 error-prone translesion synthesis R-HSA-5655862 Translesion synthesis by POLK 42276 error-prone translesion synthesis R-HSA-110312 Translesion synthesis by REV1 42276 error-prone translesion synthesis R-HSA-168874 Transport of HA trimer, NA tetramer and M2 tetramer from the endoplasmic reticulum to the Golgi Apparatus 19060 intracellular transport of viral protein in host cell R-HSA-72202 Transport of Mature Transcript to Cytoplasm 6406 mRNA export from nucleus R-HSA-9758890 Transport of RCbl within the body 15889 cobalamin transport R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 75733 intracellular transport of virus R-HSA-804914 Transport of fatty acids 15909 long-chain fatty acid transport R-HSA-159763 Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus 6888 endoplasmic reticulum to Golgi vesicle-mediated transport R-HSA-432030 Transport of glycerol from adipocytes to the liver by Aquaporins 15793 glycerol transmembrane transport R-HSA-425393 Transport of inorganic cations/anions and amino acids/oligopeptides 6811 monoatomic ion transport R-HSA-879518 Transport of organic anions 43252 sodium-independent organic anion transport R-HSA-382551 Transport of small molecules 6810 transport R-HSA-75109 Triglyceride biosynthesis 19432 triglyceride biosynthetic process R-HSA-163560 Triglyceride catabolism 19433 triglyceride catabolic process R-HSA-8979227 Triglyceride metabolism 6641 triglyceride metabolic process R-HSA-71240 Tryptophan catabolism 6569 tryptophan catabolic process R-HSA-446107 Type I hemidesmosome assembly 31581 hemidesmosome assembly R-HSA-8963684 Tyrosine catabolism 6572 tyrosine catabolic process R-HSA-2142789 Ubiquinol biosynthesis 6744 ubiquinone biosynthetic process R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 43161 proteasome-mediated ubiquitin-dependent protein catabolic process R-HSA-438066 Unblocking of NMDA receptors, glutamate binding and activation 2000310 regulation of NMDA receptor activity R-HSA-162585 Uncoating of the HIV Virion 19061 uncoating of virus R-HSA-168336 Uncoating of the Influenza Virion 19061 uncoating of virus R-HSA-381119 Unfolded Protein Response (UPR) 30968 endoplasmic reticulum unfolded protein response R-HSA-9758881 Uptake of dietary cobalamins into enterocytes 15889 cobalamin transport R-HSA-70635 Urea cycle 50 urea cycle R-HSA-77108 Utilization of Ketone Bodies 46952 ketone body catabolic process R-HSA-8866423 VLDL assembly 34379 very-low-density lipoprotein particle assembly R-HSA-8964046 VLDL clearance 34447 very-low-density lipoprotein particle clearance R-HSA-8866427 VLDLR internalisation and degradation 32802 low-density lipoprotein particle receptor catabolic process R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 3091 renal water homeostasis R-HSA-9824446 Viral Infection Pathways 9615 response to virus R-HSA-168330 Viral RNP Complexes in the Host Cell Nucleus 19070 viral genome maturation R-HSA-2187338 Visual phototransduction 7603 phototransduction, visible light R-HSA-196819 Vitamin B1 (thiamin) metabolism 42723 thiamine-containing compound metabolic process R-HSA-196843 Vitamin B2 (riboflavin) metabolism 6771 riboflavin metabolic process R-HSA-199220 Vitamin B5 (pantothenate) metabolism 15939 pantothenate metabolic process R-HSA-964975 Vitamin B6 activation to pyridoxal phosphate 42816 vitamin B6 metabolic process R-HSA-196836 Vitamin C (ascorbate) metabolism 19852 L-ascorbic acid metabolic process R-HSA-196791 Vitamin D (calciferol) metabolism 42359 vitamin D metabolic process R-HSA-8877627 Vitamin E 42360 vitamin E metabolic process R-HSA-211916 Vitamins 6766 vitamin metabolic process R-HSA-9640463 Wax biosynthesis 10025 wax biosynthetic process R-HSA-211981 Xenobiotics 6805 xenobiotic metabolic process R-HSA-2032785 YAP1- and WWTR1 (TAZ)-stimulated gene expression 6367 transcription initiation at RNA polymerase II promoter R-HSA-435354 Zinc transporters 71577 zinc ion transmembrane transport R-HSA-450302 activated TAK1 mediates p38 MAPK activation 38066 p38MAPK cascade R-HSA-2046104 alpha-linolenic (omega3) and linoleic (omega6) acid metabolism 33559 unsaturated fatty acid metabolic process R-HSA-2046106 alpha-linolenic acid (ALA) metabolism 36109 alpha-linolenic acid metabolic process R-HSA-72187 mRNA 3'-end processing 31124 mRNA 3'-end processing R-HSA-72086 mRNA Capping 6370 7-methylguanosine mRNA capping R-HSA-75072 mRNA Editing 16556 mRNA modification R-HSA-75064 mRNA Editing: A to I Conversion 6382 adenosine to inosine editing R-HSA-72200 mRNA Editing: C to U Conversion 16554 cytidine to uridine editing R-HSA-72172 mRNA Splicing 8380 RNA splicing R-HSA-72163 mRNA Splicing - Major Pathway 398 mRNA splicing, via spliceosome R-HSA-72165 mRNA Splicing - Minor Pathway 398 mRNA splicing, via spliceosome R-HSA-69563 p53-Dependent G1 DNA Damage Response 6977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest R-HSA-193704 p75 NTR receptor-mediated signalling 48011 neurotrophin TRK receptor signaling pathway R-HSA-193670 p75NTR negatively regulates cell cycle via SC1 45786 negative regulation of cell cycle R-HSA-193697 p75NTR regulates axonogenesis 50770 regulation of axonogenesis R-HSA-193639 p75NTR signals via NF-kB 43066 negative regulation of apoptotic process R-HSA-6793080 rRNA modification in the mitochondrion 154 rRNA modification R-HSA-6790901 rRNA modification in the nucleus and cytosol 154 rRNA modification R-HSA-72312 rRNA processing 6364 rRNA processing R-HSA-191859 snRNP Assembly 387 spliceosomal snRNP assembly R-HSA-379724 tRNA Aminoacylation 6418 tRNA aminoacylation for protein translation R-HSA-6787450 tRNA modification in the mitochondrion 70900 mitochondrial tRNA modification R-HSA-6782315 tRNA modification in the nucleus and cytosol 6400 tRNA modification R-HSA-72306 tRNA processing 8033 tRNA processing R-HSA-6785470 tRNA processing in the mitochondrion 90646 mitochondrial tRNA processing R-HSA-9708296 tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis 16078 tRNA decay R-HSA-199992 trans-Golgi Network Vesicle Budding 6892 post-Golgi vesicle-mediated transport