RANSOM B A R I B E F I I JACOB | RIVERS STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY (original) (raw)

Papers by RANSOM B A R I B E F I I JACOB

Hematology & Transfusion International Journal

The routine blood screening test carried out for pregnant women attending antenatal clinic in Ter... more The routine blood screening test carried out for pregnant women attending antenatal clinic in Tertiary Hospital Port Harcourt, Nigeria especially with regards to blood group system is limited to ABO/Rh D antigen screening. This cross-sectional, hospital-based study was aimed at determining the prevalence of the Rh C, c, E and e blood group antigens in multiparous women attending antenatal clinic in Tertiary Hospital Port Harcourt, Nigeria. A total of one hundred and twenty (120) pregnant females within the age range of 18-40years were recruited randomly into the study between February-June, 2022. Blood samples were aseptically collected by venipuncture into EDTA sample bottle; Rh C, c, E and e blood group antigens were assay for using microwell agglutination technique. Data generated was statistically analyzed by simple percentage calculation and defining the percentage frequency of Rh antigens. Results obtained showed the percentage distribution of 17.5% for Rh C, 89.2% for Rh c, 3...

International Journal of Immunology

Sokoto Journal of Medical Laboratory Science

Soot is a mass of impure particles of carbon obtained from incomplete hydrocarbon combustion. Soo... more Soot is a mass of impure particles of carbon obtained from incomplete hydrocarbon combustion. Soot is an ultrafine air-borne pollutant and enters into the body through ingestion, skin contact and inhalation causing devastating effects on the blood cells. The aim of the study was to determine the effect of soot inhalation on methaemoglobin and oxyhaemoglobin levels of individuals resident in both Iwofe, Port Harcourt (exposed subjects) and Ihiala, Anambra state (control subjects). The study is a case control study involving residents of Iwofe, Rumuolumeni, who have been exposed to soot pollution in the environment for an average period of one year. Iwofe is in Port Harcourt, the capital of Rivers State, Nigeria. A total of fifty (50) test samples were obtained. Thirty control samples were obtained from subjects in Ihiala a city located in the South of Anambra state where illegal oil refineries and other major means of soot generation are not as comparable to what is present in Port ...

European Journal of Clinical Medicine, 2021

Background: Turnaround Time (TAT) is an important Quality Indicator in the medical laboratory. ... more Background: Turnaround Time (TAT) is an important Quality Indicator in the medical laboratory. The Rivers State University Teaching Hospital (RSUTH) Polymerase Chain Reaction (PCR) laboratory was enrolled in the process of World Health Organisation (WHO) - Regional Office for Africa (AFRO) accreditation by FHi360 in preparation for the ISO 15189 accreditation in 2016. One of the services rendered in the laboratory is Early Infant Diagnosis (EID)/Dried Blood Spots (DBS) in Human Immunodeficiency Virus (HIV) exposed infants. Clinicians depend on these results to determine the next step for the management of HIV exposed Infants. This study is aimed at assessing the rate of sample rejection (SR), determine the effect of specific intervention on this rate and the effect of SR on TAT. Method: It involves the assessment of samples delivered to the RSUTH PCR Laboratory from January 2019 to March 2020. A baseline rate of sample rejection was established from January to July 2019. Intervent...

Journal of Advances in Microbiology, 2021

COVID-19 vaccine like other vaccines is developed to produce acquired immunity against the virus ... more COVID-19 vaccine like other vaccines is developed to produce acquired immunity against the virus which causes coronavirus disease. The spread of the virus led to quick study by various science laboratories all over the world on the preventive role and the mortality rate reduction potential of covid vaccines. Celebration has been witnessed in different part of the world for the role the vaccines played against various cases arising from coronavirus infection. This review focused on the adverse event of coronavirus vaccines with perspective to the Nigerian populace. The type of vaccines approved for use by the WHO include; viral vector vaccines which has the Oxford-Astrazenca in its class, RNA vaccines, whole virus vaccines (having the Sinopharm, and Sinovac in it class), and protein subunit vaccines (with Novavax COVID-19 vaccines and (ESI, 2021), EpiVacCorona in it class). In Nigeria, about 8,439 mild adverse reactions have been reported by the National Health Care Development Agenc...

International Blood Research & Reviews

The global burden of co-infection with human immunodeficiency virus (HIV), hepatitis B and C viru... more The global burden of co-infection with human immunodeficiency virus (HIV), hepatitis B and C virus (HBV and HCV) has a negative impact in Sub-Saharan Africa.When HIV, HBV and HCV co-exist, they become life threatening and with high fatality rate particularly in gestation in which transmission occurs vertically, causing fetal and neonatal hepatitis. The study aimed at examining the occurrence rate of Human Immunodeficiency Virus (HIV), Hepatitis B virus (HBV) and Hepatitis C Virus (HCV) co - infection among expectant mothers attending antenatal clinic in Rivers State University Teaching Hospital (RSUTH). The study population comprised of one hundred and fifty (150) pregnant women. Venous blood was used in the study and screened for hepatitis B surface antigen (HBsAg), anti-HCV, and anti-HIV antibodies using commercially available immunoassay test kits. The prevalence of HCV, HIV and HBsAg among the pregnant subjects in relation to age group 21-30 and 31-40 in the study revealed a ser...

Asian Journal of Medicine and Health, 2021

Some plants used in the management of sickle cell disease (SCD) have been shown to increase gelli... more Some plants used in the management of sickle cell disease (SCD) have been shown to increase gelling time of sickle cell blood and inhibits sickling in vitro, reversal of sickling, inhibiting osmotically induced haemolysis of erythrocytes, membrane stabilization. Plants such as Sorghum bicolar, Phyllanthus amarus, U. afzelii, Securidaca longipedunculata, Momordica charantia, Dalium guineense have been found to exhibit anti-sickling properties. The polyherbal combination of these drugs was used in this study for the investigation of the effects of anti-sickling polyherbal mixture on haematological indices in rabbits. Sixty (60) New Zealand rabbits weighing 1200g ±200g, conducted in duplicate and designated experiment X (normal rabbits) and Y (anaemia induced using Cadmium 2mg/kg +10 mg/Kg body weight phenylhydrazine for 15 days). Both groups were further subdivided into four groups (A-D) with 5 animals each, administered saline substitute, different grades of polyherbal mixtures for 8...

International Blood Research & Reviews, 2021

COVID-19 is a virus of the species of the Family coronaviridae known as as SARS-COV-2. This virus... more COVID-19 is a virus of the species of the Family coronaviridae known as as SARS-COV-2. This virus is easily contracted and/transmitted from an infected person to another healthy individual and has continued to spread rapidly. The aim of this review is to identify laboratory methods used in the diagnosis of COVID-19 infection. COVID-19 test are aimed at detecting active infection, or past infection, or an immunization so as to treat and curb the further spread of the virus. The initial viral detection is typically carried out with the upper respiratory tract (URT) sample. Repeated testing is particularly helpful and essential if a patient has a clinical appearance of viral pneumonia, radiographic results consistent with pneumonia and/or a history of potential exposure. The Centre of Disease Control and Prevention, CDC recommends the collection of specimens from the lower respiratory tract, upper respiratory tract, and the blood. The lower respiratory tract sample includes; the sputum...

Nigeria has a very high prevalence of malaria, especially among children and adolescents. The aim... more Nigeria has a very high prevalence of malaria, especially among children and adolescents. The aim of this study was to evaluate the haematological profile of adolescents before and after treatment of Plasmodium falciparum infection. It was an observational longitudinal study of 91 adolescents which comprises of 61 (67.0%) subjects with mild to moderate infection and 30 (33.0%) apparently healthy controls. The study was carried out in Nigeria National Petroleum Corporation Medical services Akpajo, Port Harcourt, Rivers state. Three milliliters of whole blood stored in EDTA bottle was used for the assays. Abacus 380 Haematological Analyzer was used for the analysis of full blood count; while malaria parasite diagnosis was done using RDT, quantitative buffy coat for malaria parasite and thick blood film. Infected subject were treated with antimalaria drug. Graph Pad Prism was used for data analysis and T-test was used to test for association. P-value of < 0.05 was considered signifi...

Aims: Burden of infectious diseases in correctional institutions constitutes a public health conc... more Aims: Burden of infectious diseases in correctional institutions constitutes a public health concern due to the confined nature and congestion of the prisons. This study aimed at surveying Burden of HIV, Tuberculosis Infection and Risk factors amongst inmates of Correctional Institutions in Port Harcourt Nigeria Study Design: The study was descriptive, comprising both males and females. A total of 178 inmates constituted the study population Place and Duration of Study: Port Harcourt Maximum Prisons, Creek Road and the Juvenile Remand Home, Borokiri, Port Harcourt, Nigeria, between the months of May to December 2019. Methodology: Two millilitres of blood was collected from each participant after receiving their informed consent. The blood was dispensed into EDTA anti-coagulant bottles and used for serological investigations of HIV 1&2, and TB. Samples positive for TB was confirmed using the Original Research Article Jeremiah et al.; IJTDH, 42(10): 34-44, 2021; Article no.IJTDH.71795...

Asian Journal of Medicine and Health

Background: Exposure to cement dust without necessary precautions to prevent its inhalation is fo... more Background: Exposure to cement dust without necessary precautions to prevent its inhalation is found to cause respiratory, dermatological, ocular as well as hematological problems and this is a matter of great concern to the health of cement loaders. Aim of Study: This study was aimed at determining haematological alterations among cement loaders in Port Harcourt, Nigeria. Study Design: Cross sectional study design. Methodology: A total of 100 apparently healthy male subject consisting of 50 cement loaders and 50 non cement loaders aged between the ages of 20- 45years old were recruited for the study. Four millilitres (4 mls) of blood was collected aseptically from the antecubital vein of each participant using standard venepuncture technique into ethylene diamine tetra acetic acid (EDTA) anticoagulated vacutainer bottles with proper mixing to avoid blood clotting and then analysed using Sysmex haematology autoanalyser. Graphpad prism version 6.2 was used to analyse the data obtaine...

Journal of Advances in Medicine and Medical Research

Haemostatic parameters constitute measurable indices in the haemostatic system used to assess the... more Haemostatic parameters constitute measurable indices in the haemostatic system used to assess the functionality of the coagulation system of an individual to establish a state of health or disorder. This study evaluated haemostatic parameter such as platelets count, mean platelet volume (MPV), platelets distribution width (PDW), prothrombin time (PT) and activated partial thromboplastin time (APTT) in 22 Male Albino Rats grouped and orally treated daily for three weeks with Sildenafil (4 mg/200 g.bwt), Tramadol(6 mg/200 g.bwt) and Sildenafil/Tramadol combination (4+6 mg/220 g.bwt). Rats were sacrificed by cardiac puncture and 5 mls of blood collected for the analysis of the parameters using Sysmex haematology analyser and Agape Diagnostic reagents kits. Results obtained shows a statistically significant increase in platelet count, PT and APTT compared with control across the various groups (p<0.05). A statistically significant decrease was observed in MPV, PDW in Sildenafil+trama...

International Blood Research & Reviews

Aim: This study assessed the level of plasma haemoglobin concentration in CPDA-1 stored blood wit... more Aim: This study assessed the level of plasma haemoglobin concentration in CPDA-1 stored blood with a view to determine the extent of haemolysis during the 35 days storage period. Study Design: This is an observational and comparative case-control study. Place and Duration of Study: The study was conducted using healthy male donors residing in Port Harcourt. Analysis was carried out at the Blood Bank of Rivers State University Teaching Hospital, formerly Braithwaite Memorial Specialist Hospital (BMSH), Port Harcourt, Nigeria, from February 1st to March 8th, 2017. Methodology: Blood for transfusion was collected from prospective male blood donor found to be in good health, aged between 18 and 52 years, with haemoglobin level within the range of 13.5 g/dl – 16 g/dl, body weight within 55 kg – 75 kg, and body temperature within 37.0 to 37.50C / 99.50F, into plastic bags containing anticoagulant CPDA-1, and handled under strict sterile condition to prevent bacterial contamination. The b...

International Journal of Translational Medical Research and Public Health

BACKGROUND OR OBJECTIVES: Pregnant women experience a lot of changes, which often reflect in thei... more BACKGROUND OR OBJECTIVES: Pregnant women experience a lot of changes, which often reflect in their hematological indices. The study examines the differences in the hematological profile of pregnant and nonpregnant women in Port Harcourt, in the Niger Delta region of Nigeria. METHODS: The subjects were systematically sampled, comprising of 90 pregnant and 90 non-pregnant women, with ages ranging 16 to 45 years. Five milliliters of whole blood was collected from each subject at ambient temperature using standard venepuncture techniques and three milliliters was dispensed in EDTA bottle. T-test was used to compare the mean of the parameters among the pregnant and nonpregnant women. Analysis of variance was used to compare the means for the parameters within the three trimesters. Tukey’s Post Hoc test was used to identify the trimester pairs that had significant mean difference, Hematological parameters were analyzed using Abacus380 hematological analyzer. The data obtained were coded a...

Hematology & Transfusion International Journal

The routine blood screening test carried out for pregnant women attending antenatal clinic in Ter... more The routine blood screening test carried out for pregnant women attending antenatal clinic in Tertiary Hospital Port Harcourt, Nigeria especially with regards to blood group system is limited to ABO/Rh D antigen screening. This cross-sectional, hospital-based study was aimed at determining the prevalence of the Rh C, c, E and e blood group antigens in multiparous women attending antenatal clinic in Tertiary Hospital Port Harcourt, Nigeria. A total of one hundred and twenty (120) pregnant females within the age range of 18-40years were recruited randomly into the study between February-June, 2022. Blood samples were aseptically collected by venipuncture into EDTA sample bottle; Rh C, c, E and e blood group antigens were assay for using microwell agglutination technique. Data generated was statistically analyzed by simple percentage calculation and defining the percentage frequency of Rh antigens. Results obtained showed the percentage distribution of 17.5% for Rh C, 89.2% for Rh c, 3...

International Journal of Immunology

Sokoto Journal of Medical Laboratory Science

Soot is a mass of impure particles of carbon obtained from incomplete hydrocarbon combustion. Soo... more Soot is a mass of impure particles of carbon obtained from incomplete hydrocarbon combustion. Soot is an ultrafine air-borne pollutant and enters into the body through ingestion, skin contact and inhalation causing devastating effects on the blood cells. The aim of the study was to determine the effect of soot inhalation on methaemoglobin and oxyhaemoglobin levels of individuals resident in both Iwofe, Port Harcourt (exposed subjects) and Ihiala, Anambra state (control subjects). The study is a case control study involving residents of Iwofe, Rumuolumeni, who have been exposed to soot pollution in the environment for an average period of one year. Iwofe is in Port Harcourt, the capital of Rivers State, Nigeria. A total of fifty (50) test samples were obtained. Thirty control samples were obtained from subjects in Ihiala a city located in the South of Anambra state where illegal oil refineries and other major means of soot generation are not as comparable to what is present in Port ...

European Journal of Clinical Medicine, 2021

Background: Turnaround Time (TAT) is an important Quality Indicator in the medical laboratory. ... more Background: Turnaround Time (TAT) is an important Quality Indicator in the medical laboratory. The Rivers State University Teaching Hospital (RSUTH) Polymerase Chain Reaction (PCR) laboratory was enrolled in the process of World Health Organisation (WHO) - Regional Office for Africa (AFRO) accreditation by FHi360 in preparation for the ISO 15189 accreditation in 2016. One of the services rendered in the laboratory is Early Infant Diagnosis (EID)/Dried Blood Spots (DBS) in Human Immunodeficiency Virus (HIV) exposed infants. Clinicians depend on these results to determine the next step for the management of HIV exposed Infants. This study is aimed at assessing the rate of sample rejection (SR), determine the effect of specific intervention on this rate and the effect of SR on TAT. Method: It involves the assessment of samples delivered to the RSUTH PCR Laboratory from January 2019 to March 2020. A baseline rate of sample rejection was established from January to July 2019. Intervent...

Journal of Advances in Microbiology, 2021

COVID-19 vaccine like other vaccines is developed to produce acquired immunity against the virus ... more COVID-19 vaccine like other vaccines is developed to produce acquired immunity against the virus which causes coronavirus disease. The spread of the virus led to quick study by various science laboratories all over the world on the preventive role and the mortality rate reduction potential of covid vaccines. Celebration has been witnessed in different part of the world for the role the vaccines played against various cases arising from coronavirus infection. This review focused on the adverse event of coronavirus vaccines with perspective to the Nigerian populace. The type of vaccines approved for use by the WHO include; viral vector vaccines which has the Oxford-Astrazenca in its class, RNA vaccines, whole virus vaccines (having the Sinopharm, and Sinovac in it class), and protein subunit vaccines (with Novavax COVID-19 vaccines and (ESI, 2021), EpiVacCorona in it class). In Nigeria, about 8,439 mild adverse reactions have been reported by the National Health Care Development Agenc...

International Blood Research & Reviews

The global burden of co-infection with human immunodeficiency virus (HIV), hepatitis B and C viru... more The global burden of co-infection with human immunodeficiency virus (HIV), hepatitis B and C virus (HBV and HCV) has a negative impact in Sub-Saharan Africa.When HIV, HBV and HCV co-exist, they become life threatening and with high fatality rate particularly in gestation in which transmission occurs vertically, causing fetal and neonatal hepatitis. The study aimed at examining the occurrence rate of Human Immunodeficiency Virus (HIV), Hepatitis B virus (HBV) and Hepatitis C Virus (HCV) co - infection among expectant mothers attending antenatal clinic in Rivers State University Teaching Hospital (RSUTH). The study population comprised of one hundred and fifty (150) pregnant women. Venous blood was used in the study and screened for hepatitis B surface antigen (HBsAg), anti-HCV, and anti-HIV antibodies using commercially available immunoassay test kits. The prevalence of HCV, HIV and HBsAg among the pregnant subjects in relation to age group 21-30 and 31-40 in the study revealed a ser...

Asian Journal of Medicine and Health, 2021

Some plants used in the management of sickle cell disease (SCD) have been shown to increase gelli... more Some plants used in the management of sickle cell disease (SCD) have been shown to increase gelling time of sickle cell blood and inhibits sickling in vitro, reversal of sickling, inhibiting osmotically induced haemolysis of erythrocytes, membrane stabilization. Plants such as Sorghum bicolar, Phyllanthus amarus, U. afzelii, Securidaca longipedunculata, Momordica charantia, Dalium guineense have been found to exhibit anti-sickling properties. The polyherbal combination of these drugs was used in this study for the investigation of the effects of anti-sickling polyherbal mixture on haematological indices in rabbits. Sixty (60) New Zealand rabbits weighing 1200g ±200g, conducted in duplicate and designated experiment X (normal rabbits) and Y (anaemia induced using Cadmium 2mg/kg +10 mg/Kg body weight phenylhydrazine for 15 days). Both groups were further subdivided into four groups (A-D) with 5 animals each, administered saline substitute, different grades of polyherbal mixtures for 8...

International Blood Research & Reviews, 2021

COVID-19 is a virus of the species of the Family coronaviridae known as as SARS-COV-2. This virus... more COVID-19 is a virus of the species of the Family coronaviridae known as as SARS-COV-2. This virus is easily contracted and/transmitted from an infected person to another healthy individual and has continued to spread rapidly. The aim of this review is to identify laboratory methods used in the diagnosis of COVID-19 infection. COVID-19 test are aimed at detecting active infection, or past infection, or an immunization so as to treat and curb the further spread of the virus. The initial viral detection is typically carried out with the upper respiratory tract (URT) sample. Repeated testing is particularly helpful and essential if a patient has a clinical appearance of viral pneumonia, radiographic results consistent with pneumonia and/or a history of potential exposure. The Centre of Disease Control and Prevention, CDC recommends the collection of specimens from the lower respiratory tract, upper respiratory tract, and the blood. The lower respiratory tract sample includes; the sputum...

Nigeria has a very high prevalence of malaria, especially among children and adolescents. The aim... more Nigeria has a very high prevalence of malaria, especially among children and adolescents. The aim of this study was to evaluate the haematological profile of adolescents before and after treatment of Plasmodium falciparum infection. It was an observational longitudinal study of 91 adolescents which comprises of 61 (67.0%) subjects with mild to moderate infection and 30 (33.0%) apparently healthy controls. The study was carried out in Nigeria National Petroleum Corporation Medical services Akpajo, Port Harcourt, Rivers state. Three milliliters of whole blood stored in EDTA bottle was used for the assays. Abacus 380 Haematological Analyzer was used for the analysis of full blood count; while malaria parasite diagnosis was done using RDT, quantitative buffy coat for malaria parasite and thick blood film. Infected subject were treated with antimalaria drug. Graph Pad Prism was used for data analysis and T-test was used to test for association. P-value of < 0.05 was considered signifi...

Aims: Burden of infectious diseases in correctional institutions constitutes a public health conc... more Aims: Burden of infectious diseases in correctional institutions constitutes a public health concern due to the confined nature and congestion of the prisons. This study aimed at surveying Burden of HIV, Tuberculosis Infection and Risk factors amongst inmates of Correctional Institutions in Port Harcourt Nigeria Study Design: The study was descriptive, comprising both males and females. A total of 178 inmates constituted the study population Place and Duration of Study: Port Harcourt Maximum Prisons, Creek Road and the Juvenile Remand Home, Borokiri, Port Harcourt, Nigeria, between the months of May to December 2019. Methodology: Two millilitres of blood was collected from each participant after receiving their informed consent. The blood was dispensed into EDTA anti-coagulant bottles and used for serological investigations of HIV 1&2, and TB. Samples positive for TB was confirmed using the Original Research Article Jeremiah et al.; IJTDH, 42(10): 34-44, 2021; Article no.IJTDH.71795...

Asian Journal of Medicine and Health

Background: Exposure to cement dust without necessary precautions to prevent its inhalation is fo... more Background: Exposure to cement dust without necessary precautions to prevent its inhalation is found to cause respiratory, dermatological, ocular as well as hematological problems and this is a matter of great concern to the health of cement loaders. Aim of Study: This study was aimed at determining haematological alterations among cement loaders in Port Harcourt, Nigeria. Study Design: Cross sectional study design. Methodology: A total of 100 apparently healthy male subject consisting of 50 cement loaders and 50 non cement loaders aged between the ages of 20- 45years old were recruited for the study. Four millilitres (4 mls) of blood was collected aseptically from the antecubital vein of each participant using standard venepuncture technique into ethylene diamine tetra acetic acid (EDTA) anticoagulated vacutainer bottles with proper mixing to avoid blood clotting and then analysed using Sysmex haematology autoanalyser. Graphpad prism version 6.2 was used to analyse the data obtaine...

Journal of Advances in Medicine and Medical Research

Haemostatic parameters constitute measurable indices in the haemostatic system used to assess the... more Haemostatic parameters constitute measurable indices in the haemostatic system used to assess the functionality of the coagulation system of an individual to establish a state of health or disorder. This study evaluated haemostatic parameter such as platelets count, mean platelet volume (MPV), platelets distribution width (PDW), prothrombin time (PT) and activated partial thromboplastin time (APTT) in 22 Male Albino Rats grouped and orally treated daily for three weeks with Sildenafil (4 mg/200 g.bwt), Tramadol(6 mg/200 g.bwt) and Sildenafil/Tramadol combination (4+6 mg/220 g.bwt). Rats were sacrificed by cardiac puncture and 5 mls of blood collected for the analysis of the parameters using Sysmex haematology analyser and Agape Diagnostic reagents kits. Results obtained shows a statistically significant increase in platelet count, PT and APTT compared with control across the various groups (p<0.05). A statistically significant decrease was observed in MPV, PDW in Sildenafil+trama...

International Blood Research & Reviews

Aim: This study assessed the level of plasma haemoglobin concentration in CPDA-1 stored blood wit... more Aim: This study assessed the level of plasma haemoglobin concentration in CPDA-1 stored blood with a view to determine the extent of haemolysis during the 35 days storage period. Study Design: This is an observational and comparative case-control study. Place and Duration of Study: The study was conducted using healthy male donors residing in Port Harcourt. Analysis was carried out at the Blood Bank of Rivers State University Teaching Hospital, formerly Braithwaite Memorial Specialist Hospital (BMSH), Port Harcourt, Nigeria, from February 1st to March 8th, 2017. Methodology: Blood for transfusion was collected from prospective male blood donor found to be in good health, aged between 18 and 52 years, with haemoglobin level within the range of 13.5 g/dl – 16 g/dl, body weight within 55 kg – 75 kg, and body temperature within 37.0 to 37.50C / 99.50F, into plastic bags containing anticoagulant CPDA-1, and handled under strict sterile condition to prevent bacterial contamination. The b...

International Journal of Translational Medical Research and Public Health

BACKGROUND OR OBJECTIVES: Pregnant women experience a lot of changes, which often reflect in thei... more BACKGROUND OR OBJECTIVES: Pregnant women experience a lot of changes, which often reflect in their hematological indices. The study examines the differences in the hematological profile of pregnant and nonpregnant women in Port Harcourt, in the Niger Delta region of Nigeria. METHODS: The subjects were systematically sampled, comprising of 90 pregnant and 90 non-pregnant women, with ages ranging 16 to 45 years. Five milliliters of whole blood was collected from each subject at ambient temperature using standard venepuncture techniques and three milliliters was dispensed in EDTA bottle. T-test was used to compare the mean of the parameters among the pregnant and nonpregnant women. Analysis of variance was used to compare the means for the parameters within the three trimesters. Tukey’s Post Hoc test was used to identify the trimester pairs that had significant mean difference, Hematological parameters were analyzed using Abacus380 hematological analyzer. The data obtained were coded a...