Esther Smits | University of Groningen (original) (raw)

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Research paper thumbnail of Standardized Handwriting to assess bradykinesia, micrographia and tremor in Parkinson's disease

Research paper thumbnail of Standardized handwriting to assess bradykinesia, micrographia and tremor in Parkinson's disease

PloS one, 2014

To assess whether standardized handwriting can provide quantitative measures to distinguish patie... more To assess whether standardized handwriting can provide quantitative measures to distinguish patients diagnosed with Parkinson's disease from age- and gender-matched healthy control participants. Exploratory study. Pen tip trajectories were recorded during circle, spiral and line drawing and repeated character 'elelelel' and sentence writing, performed by Parkinson patients and healthy control participants. Parkinson patients were tested after overnight withdrawal of anti-Parkinsonian medication. University Medical Center Groningen, tertiary care, the Netherlands. Patients with Parkinson's disease (n = 10; mean age 69.0 years; 6 male) and healthy controls (n = 10; mean age 68.1 years; 6 male). Not applicable. Movement time and velocity to detect bradykinesia and the size of writing to detect micrographia. A rest recording to investigate the presence of a rest-tremor, by frequency analysis. Mean disease duration in the Parkinson group was 4.4 years and the patients wer...

Research paper thumbnail of Standardized Handwriting to assess bradykinesia, micrographia and tremor in Parkinson's disease

Research paper thumbnail of Standardized handwriting to assess bradykinesia, micrographia and tremor in Parkinson's disease

PloS one, 2014

To assess whether standardized handwriting can provide quantitative measures to distinguish patie... more To assess whether standardized handwriting can provide quantitative measures to distinguish patients diagnosed with Parkinson's disease from age- and gender-matched healthy control participants. Exploratory study. Pen tip trajectories were recorded during circle, spiral and line drawing and repeated character 'elelelel' and sentence writing, performed by Parkinson patients and healthy control participants. Parkinson patients were tested after overnight withdrawal of anti-Parkinsonian medication. University Medical Center Groningen, tertiary care, the Netherlands. Patients with Parkinson's disease (n = 10; mean age 69.0 years; 6 male) and healthy controls (n = 10; mean age 68.1 years; 6 male). Not applicable. Movement time and velocity to detect bradykinesia and the size of writing to detect micrographia. A rest recording to investigate the presence of a rest-tremor, by frequency analysis. Mean disease duration in the Parkinson group was 4.4 years and the patients wer...

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