Gert J ter Horst | University of Groningen (original) (raw)

Uploads

Papers by Gert J ter Horst

Research paper thumbnail of Valence processing differs across stimulus modalities

Research paper thumbnail of The hypothalamus, intrinsic connections and outflow pathways to the endocrine system in relation to the control of feeding and metabolism

Progress in Neurobiology, 1987

Research paper thumbnail of The role of emotions in food choice and liking

Food Research International, 2015

Research paper thumbnail of Stressverwerking door het mannelijke en vrouwelijke brein: relevantie voor de psychiatrie

Research paper thumbnail of Reduced spatiotemporal brain dynamics are associated with increased depressive symptoms after a relationship breakup

Research paper thumbnail of Anatomical demonstration of the suprachiasmatic nucleus-pineal pathway

The Journal of Comparative Neurology, 1999

A polysynaptic pathway is proposed to transmit light information from the retina through the supr... more A polysynaptic pathway is proposed to transmit light information from the retina through the suprachiasmatic nucleus of the hypothalamus (SCN) to the pineal. In the present study, the powerful transneuronal tracer, pseudorabies virus (PRV), was used to provide a detailed description of this pathway. PRV injected into the pineal subsequently labeled the superior cervical ganglion, the intermediolateral column of the upper thoracic cord, the autonomic division of the paraventricular nucleus of the hypothalamus (PVN), and the SCN. Neurons in the autonomic division of the PVN were the only PRV-labeled neurons in the hypothalamus shown to receive input from the SCN as demonstrated by the presence of vasoactive intestinal polypeptide axonal contacts. This observation concurred with the presence of ventrally placed neurons in the SCN that could only be observed a day after the appearance of PVN-labeled neurons. Nevertheless the majority of the neurons were found in the dorsomedial position of the SCN, associated with the vasopressin-containing population of SCN neurons. Confocal laser scanning microscopy showed double-labeled neurons containing PRV and vasopressin or PRV and vasoactive intestinal polypeptide. Specificity of tracing was also established by prior removal of the superior cervical ganglion, resulting in a complete absence of the tracer but in the pineal. Thus, the present study provides the anatomical basis for circadian control of melatonin secretion.

Research paper thumbnail of Origin, distribution and morphology of serotonergic afferents to the mesencephalic trigeminal nucleus of the rat

Neuroscience letters, 1991

We have studied the localization, the morphology and sources of serotonergic input on the primary... more We have studied the localization, the morphology and sources of serotonergic input on the primary afferent neurons in the mesencephalic trigeminal nucleus (Me5) of the rat with light and electronmicroscopy immunocytochemistry and with anterograde and retrograde neuroanatomical tract tracing methods. Me5 neurons were found to receive a serotonergic input that is part of a serotonergic fibre plexus extending over the neighbouring parabrachial nucleus and locus coeruleus. These serotonergic afferents originate predominantly from serotonergic cells in the dorsal raphe nucleus.

Research paper thumbnail of A device for enhancing the visibility of the tip of a glass micropipette: Application in neuroanatomy

Brain Research Bulletin, 1988

Research paper thumbnail of Phaseolus vulgaris leuco-agglutinin immunohistochemistry. A comparison between autoradiographic and lectin tracing of neuronal efferents

Research paper thumbnail of Migraine and function of the immune system: a meta‐analysis of clinical literature published between 1966 and 1999

Research paper thumbnail of The course of paraventricular hypothalamic efferents to autonomic structures in medulla and spinal cord

Brain Research, 1985

374 Brain Research. 329 ( 19851374 -37~;[Slscxic~BRE 20675The course of paraventricular hypothala... more 374 Brain Research. 329 ( 19851374 -37~;[Slscxic~BRE 20675The course of paraventricular hypothalamic efferents to autonomic structures inmedulla and spinal cordP. GM LUITEN, GJ ter HORST, H. KARST and AB STEFFENSDepartment of Animal Physiology, State ...

Research paper thumbnail of Contralateral projections of cells in the motor trigeminal nucleus of the rat

Neuroscience Letters, 1990

Research paper thumbnail of The Dynamics of Functional Brain Networks Associated With Depressive Symptoms in a Nonclinical Sample

Frontiers in Neural Circuits

Research paper thumbnail of Friends with benefits: Behavioral and fMRI studies on the effect of friendship reminders on self-control for compulsive and non-compulsive buyers

International Journal of Research in Marketing

Research paper thumbnail of T1 vs. T2 weighted magnetic resonance imaging to assess total kidney volume in patients with autosomal dominant polycystic kidney disease

Research paper thumbnail of Flavor pleasantness processing in the ventral emotion network

PloS one, 2017

The ventral emotion network-encompassing the amygdala, insula, ventral striatum, and ventral regi... more The ventral emotion network-encompassing the amygdala, insula, ventral striatum, and ventral regions of the prefrontal cortex-has been associated with the identification of emotional significance of perceived external stimuli and the production of affective states. Functional magnetic resonance imaging (fMRI) studies investigating chemosensory stimuli have associated parts of this network with pleasantness coding. In the current study, we independently analyzed two datasets in which we measured brain responses to flavor stimuli in young adult men. In the first dataset, participants evaluated eight regular off the shelf drinking products while participants evaluated six less familiar oral nutritional supplements (ONS) in the second dataset. Participants provided pleasantness ratings 20 seconds after tasting. Using independent component analysis (ICA) and mixed effect models, we identified one brain network in the regular products dataset that was associated with flavor pleasantness. ...

Research paper thumbnail of Metallic Taste in Cancer Patients Treated with Systemic Therapy: A Questionnaire-based Study

Nutrition and Cancer, 2016

Research paper thumbnail of Changes in taste and smell function, dietary intake, food preference, and body composition in testicular cancer patients treated with cisplatin-based chemotherapy

Clinical Nutrition, 2016

Taste and smell changes due to chemotherapy may contribute to the high prevalence of overweight i... more Taste and smell changes due to chemotherapy may contribute to the high prevalence of overweight in testicular cancer patients (TCPs). This study investigates the taste and smell function, dietary intake, food preference, and body composition in TCPs before, during, and up to 1 year after cisplatin-based chemotherapy. Twenty-one consecutive TCPs participated. At baseline TCPs were compared to healthy controls (N = 48). Taste strips and 'Sniffin' Sticks' were used to determine psychophysical taste and smell function. Subjective taste, smell, appetite, and hunger were assessed using a questionnaire. Dietary intake was analyzed using a food frequency questionnaire. Food preference was assessed using food pictures varying in taste (sweet/savoury) and fat or protein content. A Dual-Energy X-ray Absorptiometry (DEXA) scan was performed to measure whole body composition. Compared to controls, TCPs had a lower smell threshold (P = 0.045) and lower preference for high fat sweet foods at baseline (P = 0.024). Over time, intra-individual psychophysical taste and smell function was highly variable. The salty taste threshold increased at completion of chemotherapy compared to baseline (P = 0.006). A transient decrease of subjective taste, appetite, and hunger feelings was observed per chemotherapy cycle. The percentage of fat mass increased during chemotherapy compared to baseline, while the lean mass and bone density decreased (P < 0.05). Coping strategies regarding subjective taste impairment should especially be provided during the first week of each chemotherapy cycle. Since the body composition of TCPs already had changed at completion of chemotherapy, intervention strategies to limit the impact of cardiovascular risk factors should probably start during treatment.

Research paper thumbnail of The palatability of oral nutritional supplements: before, during, and after chemotherapy

Supportive Care in Cancer, 2016

Research paper thumbnail of Activation of a Non-Specific Immune Response in Cadaveric Donor Livers

Research paper thumbnail of Valence processing differs across stimulus modalities

Research paper thumbnail of The hypothalamus, intrinsic connections and outflow pathways to the endocrine system in relation to the control of feeding and metabolism

Progress in Neurobiology, 1987

Research paper thumbnail of The role of emotions in food choice and liking

Food Research International, 2015

Research paper thumbnail of Stressverwerking door het mannelijke en vrouwelijke brein: relevantie voor de psychiatrie

Research paper thumbnail of Reduced spatiotemporal brain dynamics are associated with increased depressive symptoms after a relationship breakup

Research paper thumbnail of Anatomical demonstration of the suprachiasmatic nucleus-pineal pathway

The Journal of Comparative Neurology, 1999

A polysynaptic pathway is proposed to transmit light information from the retina through the supr... more A polysynaptic pathway is proposed to transmit light information from the retina through the suprachiasmatic nucleus of the hypothalamus (SCN) to the pineal. In the present study, the powerful transneuronal tracer, pseudorabies virus (PRV), was used to provide a detailed description of this pathway. PRV injected into the pineal subsequently labeled the superior cervical ganglion, the intermediolateral column of the upper thoracic cord, the autonomic division of the paraventricular nucleus of the hypothalamus (PVN), and the SCN. Neurons in the autonomic division of the PVN were the only PRV-labeled neurons in the hypothalamus shown to receive input from the SCN as demonstrated by the presence of vasoactive intestinal polypeptide axonal contacts. This observation concurred with the presence of ventrally placed neurons in the SCN that could only be observed a day after the appearance of PVN-labeled neurons. Nevertheless the majority of the neurons were found in the dorsomedial position of the SCN, associated with the vasopressin-containing population of SCN neurons. Confocal laser scanning microscopy showed double-labeled neurons containing PRV and vasopressin or PRV and vasoactive intestinal polypeptide. Specificity of tracing was also established by prior removal of the superior cervical ganglion, resulting in a complete absence of the tracer but in the pineal. Thus, the present study provides the anatomical basis for circadian control of melatonin secretion.

Research paper thumbnail of Origin, distribution and morphology of serotonergic afferents to the mesencephalic trigeminal nucleus of the rat

Neuroscience letters, 1991

We have studied the localization, the morphology and sources of serotonergic input on the primary... more We have studied the localization, the morphology and sources of serotonergic input on the primary afferent neurons in the mesencephalic trigeminal nucleus (Me5) of the rat with light and electronmicroscopy immunocytochemistry and with anterograde and retrograde neuroanatomical tract tracing methods. Me5 neurons were found to receive a serotonergic input that is part of a serotonergic fibre plexus extending over the neighbouring parabrachial nucleus and locus coeruleus. These serotonergic afferents originate predominantly from serotonergic cells in the dorsal raphe nucleus.

Research paper thumbnail of A device for enhancing the visibility of the tip of a glass micropipette: Application in neuroanatomy

Brain Research Bulletin, 1988

Research paper thumbnail of Phaseolus vulgaris leuco-agglutinin immunohistochemistry. A comparison between autoradiographic and lectin tracing of neuronal efferents

Research paper thumbnail of Migraine and function of the immune system: a meta‐analysis of clinical literature published between 1966 and 1999

Research paper thumbnail of The course of paraventricular hypothalamic efferents to autonomic structures in medulla and spinal cord

Brain Research, 1985

374 Brain Research. 329 ( 19851374 -37~;[Slscxic~BRE 20675The course of paraventricular hypothala... more 374 Brain Research. 329 ( 19851374 -37~;[Slscxic~BRE 20675The course of paraventricular hypothalamic efferents to autonomic structures inmedulla and spinal cordP. GM LUITEN, GJ ter HORST, H. KARST and AB STEFFENSDepartment of Animal Physiology, State ...

Research paper thumbnail of Contralateral projections of cells in the motor trigeminal nucleus of the rat

Neuroscience Letters, 1990

Research paper thumbnail of The Dynamics of Functional Brain Networks Associated With Depressive Symptoms in a Nonclinical Sample

Frontiers in Neural Circuits

Research paper thumbnail of Friends with benefits: Behavioral and fMRI studies on the effect of friendship reminders on self-control for compulsive and non-compulsive buyers

International Journal of Research in Marketing

Research paper thumbnail of T1 vs. T2 weighted magnetic resonance imaging to assess total kidney volume in patients with autosomal dominant polycystic kidney disease

Research paper thumbnail of Flavor pleasantness processing in the ventral emotion network

PloS one, 2017

The ventral emotion network-encompassing the amygdala, insula, ventral striatum, and ventral regi... more The ventral emotion network-encompassing the amygdala, insula, ventral striatum, and ventral regions of the prefrontal cortex-has been associated with the identification of emotional significance of perceived external stimuli and the production of affective states. Functional magnetic resonance imaging (fMRI) studies investigating chemosensory stimuli have associated parts of this network with pleasantness coding. In the current study, we independently analyzed two datasets in which we measured brain responses to flavor stimuli in young adult men. In the first dataset, participants evaluated eight regular off the shelf drinking products while participants evaluated six less familiar oral nutritional supplements (ONS) in the second dataset. Participants provided pleasantness ratings 20 seconds after tasting. Using independent component analysis (ICA) and mixed effect models, we identified one brain network in the regular products dataset that was associated with flavor pleasantness. ...

Research paper thumbnail of Metallic Taste in Cancer Patients Treated with Systemic Therapy: A Questionnaire-based Study

Nutrition and Cancer, 2016

Research paper thumbnail of Changes in taste and smell function, dietary intake, food preference, and body composition in testicular cancer patients treated with cisplatin-based chemotherapy

Clinical Nutrition, 2016

Taste and smell changes due to chemotherapy may contribute to the high prevalence of overweight i... more Taste and smell changes due to chemotherapy may contribute to the high prevalence of overweight in testicular cancer patients (TCPs). This study investigates the taste and smell function, dietary intake, food preference, and body composition in TCPs before, during, and up to 1 year after cisplatin-based chemotherapy. Twenty-one consecutive TCPs participated. At baseline TCPs were compared to healthy controls (N = 48). Taste strips and 'Sniffin' Sticks' were used to determine psychophysical taste and smell function. Subjective taste, smell, appetite, and hunger were assessed using a questionnaire. Dietary intake was analyzed using a food frequency questionnaire. Food preference was assessed using food pictures varying in taste (sweet/savoury) and fat or protein content. A Dual-Energy X-ray Absorptiometry (DEXA) scan was performed to measure whole body composition. Compared to controls, TCPs had a lower smell threshold (P = 0.045) and lower preference for high fat sweet foods at baseline (P = 0.024). Over time, intra-individual psychophysical taste and smell function was highly variable. The salty taste threshold increased at completion of chemotherapy compared to baseline (P = 0.006). A transient decrease of subjective taste, appetite, and hunger feelings was observed per chemotherapy cycle. The percentage of fat mass increased during chemotherapy compared to baseline, while the lean mass and bone density decreased (P < 0.05). Coping strategies regarding subjective taste impairment should especially be provided during the first week of each chemotherapy cycle. Since the body composition of TCPs already had changed at completion of chemotherapy, intervention strategies to limit the impact of cardiovascular risk factors should probably start during treatment.

Research paper thumbnail of The palatability of oral nutritional supplements: before, during, and after chemotherapy

Supportive Care in Cancer, 2016

Research paper thumbnail of Activation of a Non-Specific Immune Response in Cadaveric Donor Livers