Saravana Mech | Sree Sastha Institute Of Engineering And Technology (original) (raw)

Papers by Saravana Mech

International Journal of Industrial Ergonomics, 1997

A three dimensional (3D) human modeling program has been developed to work in conjunction with co... more A three dimensional (3D) human modeling program has been developed to work in conjunction with computer aided design software, Autocad. The program allows the creation and manipulation of variable size, 3D human models and provides the flexibility of a professional CAD system. The special features of the program and its application in workstation design are described and illustrated with examples. This program operates on a personal computer and provides a low cost but effective alternative to main-frame based similar systems.

Proceedings of The Institution of Mechanical Engineers Part J-journal of Engineering Tribology, 2007

ABSTRACT

Engineering Fracture Mechanics, 1994

An iterative approach is proposed for the soil-structure interaction of tall buildings having clo... more An iterative approach is proposed for the soil-structure interaction of tall buildings having closely spaced independent footings. A software package has been developed and several plane frame problems have been analysed. Results are compared with those obtained with fixed base ...

Journal of Mechanical Design, 2002

Some engineering applications require structures to expand and contract in size, while retaining ... more Some engineering applications require structures to expand and contract in size, while retaining their exterior shape. The applications range from mundane daily life objects to more fancy art structures. In contrast to a multi degree-of-freedom structure, a single degree-of-freedom structure can be driven by a single actuator, reducing cost and simplifying the control. In this paper, we study single degree-of-freedom structures that can be formed by a lattice of single degree-of-freedom polyhedral expanding units. Due to built-in symmetries, the entire structure can expand and contract as one of the units in the structure is actuated.

Toxicology Mechanisms and Methods, 2007

ABSTRACT In this research work we developed in vitro tests utilizing mammalian cell cultures, whi... more ABSTRACT In this research work we developed in vitro tests utilizing mammalian cell cultures, which can rapidly assess effect of exposure of oily sludge-derived chemicals on human and ecological health. Many of these are hazardous to health and environment due to their toxicity and/or accumulation potential in sediments as well as in organisms. Petroleum refinery and petrochemical industry-derived oily sludges contain toxic polycyclic aromatic hydrocarbons (PAHs), some of which are lipophilic in nature. Risk assessment of environmental samples suffers from inadequate availability of toxicity data, lack of knowledge about behavior of genotoxic substances in complex matrices, paucity of information on synergistic and antagonistic interactions of mixture of components, etc.; the literature describing the behavior of genotoxic substances in complex mixtures is sparse and sometimes contradictory. The present study aims at assessing the genotoxic potential of oily sludges collected from an integrated petroleum refinery and petrochemical industry located in the southwestern part of India and a petrochemical industry located in the western part of India using a battery of genotoxicity assays such as DNA damage/strand break, chromosomal aberration, p(53) protein induction, and apoptosis in CHO-K1 cell culture system. Exposure with different dose levels of sludge extracts (25, 50, 100 muL) in CHO-K1 cells could cause statistically significant level of (P &amp;amp;amp;amp;amp;lt; 0.001) DNA damage, chromosomal aberration, p(53) protein induction, and apoptosis in comparison to negative control treatment groups, and the genotoxicity was attributed to PAHs present in the sludge as identified by GC-MS. This implies that the sludges are genotoxic in nature in mammalian cells tested, and the exposure to these may pose a potential genotoxic risk to human beings.

Proceedings of The Institution of Mechanical Engineers Part H-journal of Engineering in Medicine, 2010

Tissue engineering scaffolds with intricate and controlled internal structure can be realized usi... more Tissue engineering scaffolds with intricate and controlled internal structure can be realized using computer-aided design (CAD) and layer manufacturing (LM) techniques. Design and manufacturing of scaffolds for load-bearing bone sites should consider appropriate biocompatibile materials with interconnected porosity, surface properties, and sufficient mechanical properties that match the surrounding bone, in order to provide adequate support, and to mimic the physiological stress-strain state so as to stimulate new tissue growth. The authors have previously published methods for estimating subject- and site-specific bone modulus using computed tomography (CT) data, CAD, and process planning for LM of controlled porous scaffolds. This study evaluates the mechanical performance of the designed porous hydroxyapite scaffolds in load-bearing sites using a finite element (FE) approach. A subject-specific FE analysis using femoral, defect site geometry and anisotropic material assignment based on CT data is employed. Mechanical behaviour of the femur with scaffold in stance-phase gait loading, which has been shown experimentally to produce clinically relevant results, is analysed. The comparison of results with simulation of healthy femur shows an overall correspondence in stress and strain state which will provide optimized mechanical properties for avoiding stress shielding, and adequate strength to avoid failure risk and for active bone tissue regeneration.