Sunjit Parmar | SUNY: Stony Brook University (original) (raw)
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Papers by Sunjit Parmar
Journal of orthopaedic surgery and research, Jan 22, 2017
One of the major challenges in orthopedics is to develop implants that overcome current postopera... more One of the major challenges in orthopedics is to develop implants that overcome current postoperative problems such as osteointegration, proper load bearing, and stress shielding. Current implant techniques such as allografts or endoprostheses never reach full bone integration, and the risk of fracture due to stress shielding is a major concern. To overcome this, a novel technique of reverse engineering to create artificial scaffolds was designed and tested. The purpose of the study is to create a new generation of implants that are both biocompatible and biomimetic. 3D-printed scaffolds based on physiological trabecular bone patterning were printed. MC3T3 cells were cultured on these scaffolds in osteogenic media, with and without the addition of Calcitonin Receptor Fragment Peptide (CRFP) in order to assess bone formation on the surfaces of the scaffolds. Integrity of these cell-seeded bone-coated scaffolds was tested for their mechanical strength. The results show that cellular p...
Journal of orthopaedic surgery and research, Jan 19, 2018
J ORTHOP SURG RES (2017) 12: 195. HTTPS://DOI.ORG/10.1186/S13018-017-0700-2: In the original publ... more J ORTHOP SURG RES (2017) 12: 195. HTTPS://DOI.ORG/10.1186/S13018-017-0700-2: In the original publication of this article [1] there was an error in one of the author names. In this publication the correct and incorrect name are indicated.
Biomedical Reports, 2016
As the most common noncutaneous malignancy in American men, prostate cancer currently accounts fo... more As the most common noncutaneous malignancy in American men, prostate cancer currently accounts for 29% of all diagnosed cancers, and ranks second as the cause of cancer fatality in American men. Prostatic cancer is rarely symptomatic early in its course and therefore disease presentation often implies local extension or even metastatic disease. Thus, it is extremely critical to detect and diagnose prostate cancer in its earliest stages, often prior to the presentation of symptoms. Three of the most common techniques used to detect prostate cancer are the digital rectal exam, the transrectal ultrasound, and the use of biomarkers. This review presents an update regarding the field of prostate cancer biomarkers and comments on future biomarkers. Although there is not a lack of research in the field of prostate cancer biomarkers, the discovery of a novel biomarker that may have the advantage of being more specific and effective warrants future scientific inquiry.
Journal of orthopaedic surgery and research, Jan 22, 2017
One of the major challenges in orthopedics is to develop implants that overcome current postopera... more One of the major challenges in orthopedics is to develop implants that overcome current postoperative problems such as osteointegration, proper load bearing, and stress shielding. Current implant techniques such as allografts or endoprostheses never reach full bone integration, and the risk of fracture due to stress shielding is a major concern. To overcome this, a novel technique of reverse engineering to create artificial scaffolds was designed and tested. The purpose of the study is to create a new generation of implants that are both biocompatible and biomimetic. 3D-printed scaffolds based on physiological trabecular bone patterning were printed. MC3T3 cells were cultured on these scaffolds in osteogenic media, with and without the addition of Calcitonin Receptor Fragment Peptide (CRFP) in order to assess bone formation on the surfaces of the scaffolds. Integrity of these cell-seeded bone-coated scaffolds was tested for their mechanical strength. The results show that cellular p...
Journal of orthopaedic surgery and research, Jan 19, 2018
J ORTHOP SURG RES (2017) 12: 195. HTTPS://DOI.ORG/10.1186/S13018-017-0700-2: In the original publ... more J ORTHOP SURG RES (2017) 12: 195. HTTPS://DOI.ORG/10.1186/S13018-017-0700-2: In the original publication of this article [1] there was an error in one of the author names. In this publication the correct and incorrect name are indicated.
Biomedical Reports, 2016
As the most common noncutaneous malignancy in American men, prostate cancer currently accounts fo... more As the most common noncutaneous malignancy in American men, prostate cancer currently accounts for 29% of all diagnosed cancers, and ranks second as the cause of cancer fatality in American men. Prostatic cancer is rarely symptomatic early in its course and therefore disease presentation often implies local extension or even metastatic disease. Thus, it is extremely critical to detect and diagnose prostate cancer in its earliest stages, often prior to the presentation of symptoms. Three of the most common techniques used to detect prostate cancer are the digital rectal exam, the transrectal ultrasound, and the use of biomarkers. This review presents an update regarding the field of prostate cancer biomarkers and comments on future biomarkers. Although there is not a lack of research in the field of prostate cancer biomarkers, the discovery of a novel biomarker that may have the advantage of being more specific and effective warrants future scientific inquiry.