Humsheer Sethi | Kalinga Institute of Industrial Technology (KIIT) (original) (raw)

Papers by Humsheer Sethi

Indian journal of respiratory care, 2022

After almost 2 years of the coronavirus disease epidemic, the mortality is staggeringly higher, a... more After almost 2 years of the coronavirus disease epidemic, the mortality is staggeringly higher, at over 10 million. [1] Fortunately, there are a number of effective vaccinations available now that might aid in the containment of the coronavirus disease-2019 (COVID-19) epidemic. However, our vaccination efforts must battle the rapidly increasing severe acute respiratory syndrome coronavirus (SARS-CoV-2) strains, which are a huge problem. SARS-CoV-2 has developed into new fatal strains than their predecessors, the most dangerous of which is the delta type. These mutations are worrisome due to their higher chances of transmission, symptom severity, and immune evasion, creating a risk of reinfection in convalescents or breakthrough infections in vaccinated people. [2] To limit the epidemic, which has had severe medical, economic, and societal implications, safe and efficient preventive vaccinations are required even though some are still getting infected during postvaccination status. This research aims to investigate the limits and extents of pulmonary involvement in vaccinated patients of COVID-19 and the relationship between vaccination status and lung severity. Two vaccines were developed in India at the time of this research, both of which required two doses and a booster for full immunization. [3] Methods We retrospectively analyzed our COVID-19-related high-resolution computed tomography (HRCT) of thorax data from April to August 2021. This was done to identify positive patients on reverse transcription-polymerase chain reaction (RT-PCR) who have undergone a HRCT of the thorax to analyze the extent of pulmonary involvement by applying the computed tomography severity score (CTSS).

The Neuroradiology Journal

Pituitary gland duplication is a rare abnormality and isolated duplication of the pituitary stalk... more Pituitary gland duplication is a rare abnormality and isolated duplication of the pituitary stalk without any pituitary anomaly is an even rarer entity with this case being the first documented case till date. Although incidentally discovered cases of duplication of pituitary gland (DPG) have been reported, sometimes with a duplicated pituitary stalk, patients with this disorder usually present with other craniofacial abnormalities. Consequently, DPG plus syndrome is used as it is often accompanied by endocrine disturbances and pathologies such as median cleft face syndrome, ocular disorders, craniocervical bony abnormalities, vascular anomalies and tuberomammillary masses. Since this is the first reported case without any additional pituitary gland anomaly, we propose the acronym DPS (duplication of pituitary stalk) to be used to unify this entity as we are certain that much like the previously described pituitary duplication disorders, more cases will be documented independently r...

Indian Journal of Respiratory Care

After almost 2 years of the coronavirus disease epidemic, the mortality is staggeringly higher, a... more After almost 2 years of the coronavirus disease epidemic, the mortality is staggeringly higher, at over 10 million. [1] Fortunately, there are a number of effective vaccinations available now that might aid in the containment of the coronavirus disease-2019 (COVID-19) epidemic. However, our vaccination efforts must battle the rapidly increasing severe acute respiratory syndrome coronavirus (SARS-CoV-2) strains, which are a huge problem. SARS-CoV-2 has developed into new fatal strains than their predecessors, the most dangerous of which is the delta type. These mutations are worrisome due to their higher chances of transmission, symptom severity, and immune evasion, creating a risk of reinfection in convalescents or breakthrough infections in vaccinated people. [2] To limit the epidemic, which has had severe medical, economic, and societal implications, safe and efficient preventive vaccinations are required even though some are still getting infected during postvaccination status. This research aims to investigate the limits and extents of pulmonary involvement in vaccinated patients of COVID-19 and the relationship between vaccination status and lung severity. Two vaccines were developed in India at the time of this research, both of which required two doses and a booster for full immunization. [3] Methods We retrospectively analyzed our COVID-19-related high-resolution computed tomography (HRCT) of thorax data from April to August 2021. This was done to identify positive patients on reverse transcription-polymerase chain reaction (RT-PCR) who have undergone a HRCT of the thorax to analyze the extent of pulmonary involvement by applying the computed tomography severity score (CTSS).

Indian Journal of Radiology and Imaging

Background The information-seeking behavior of the radiology residents on call has undergone mode... more Background The information-seeking behavior of the radiology residents on call has undergone modernization in the recent times given the advent of easy to access, reliable online resources, and robust artificial intelligence chatbots such as Chat Generative Pre-Trained Transformer (ChatGPT). Purpose The aim of this study was to conduct a baseline analysis among the residents to understand the best way to meet information needs in the future, spread awareness about the existing resources, and narrow down to the most preferred online resource. Methods and Materials A prospective, descriptive study was performed using an online survey instrument and was conducted among radiology residents in India. They were questioned on their demographics, frequency of on call, fatigue experienced on call, and preferred information resources and reasons for choosing them. Results A total of 286 residents participated in the survey. All residents had used the Internet radiology resources during on-cal...

The Egyptian Journal of Radiology and Nuclear Medicine, 2021

Background There has been a rapid rise in the number of COVID-19-associated rhino-orbital mucormy... more Background There has been a rapid rise in the number of COVID-19-associated rhino-orbital mucormycosis (CAROM) cases especially in South Asian countries, to an extent that it has been considered an epidemic among the COVID-19 patients in India. As of May 13, 2021, 101 CAROM cases have been reported, of which 82 cases were from India and 19 from the rest of the world. On the other hand, pulmonary mucormycosis associated with COVID-19 has a much lesser reported incidence of only 7% of the total COVID-19-associated mucormycosis cases (Singh AK, Singh R, Joshi SR, Misra A, Diab Metab Syndr: Clin Res Rev, 2021). This case report attempts to familiarize the health care professionals and radiologists with the imaging findings that should alarm for follow-up and treatment in the lines of CAROM. Case presentation Rhino-orbital mucormycosis (ROM) is a manifestation of mucormycosis that is thought to be acquired by inhalation of fungal spores into the paranasal sinuses. Here, we describe a 55-...

The Egyptian Journal of Radiology and Nuclear Medicine, 2021

Background High-resolution computed tomography (HRCT) chest becomes a valuable diagnostic tool fo... more Background High-resolution computed tomography (HRCT) chest becomes a valuable diagnostic tool for identifying patients infected with Coronavirus Disease 2019 (COVID-19) in the early stage, where patients may be asymptomatic or with non-specific pulmonary symptoms. An early diagnosis of COVID-19 is of utmost importance, so that patients can be isolated and treated in time, eventually preventing spread of the disease, improving the prognosis and reducing the mortality. In this paper, we have highlighted our radiological experience of dealing with the pandemic crisis of 2020 through the study of HRCT thorax, lung ultrasonography, chest X-rays and artificial intelligence (AI). Results Results of CT thorax analysis have been given in detail. We had also compared CT severity score (CTSS) with clinical and laboratory parameters. Correlation of CTSS with SpO2 values and comorbidities was also studied. We also analysed manual CTSS with the CTSS scored calculated by the AI software. Conclusi...

Background: The objectives were to perform an analysis of lung ultrasonography (LUS) findings in ... more Background: The objectives were to perform an analysis of lung ultrasonography (LUS) findings in severely ill patients with novel coronavirus disease-2019 (COVID-19) and to compare the accuracy with high-resolution computed tomography (HRCT) of the thorax. Methods: Sixty-two intensive care unit (ICU) patients with COVID-19 were evaluated during their hospital stay. LUS was performed with convex and linear transducers using a designated ultrasonography machine placed in the COVID-19 ICU. The thorax was scanned in 12 areas. Initial LUS was performed on admission and follow-up LUS was done in 7 (mean) days. At the time of the initial LUS, HRCT was performed in 28/62 patients and a chest radiography in 19/62 patients. Results: On admission, LUS detected pleural line thickening (>6 lung areas) in 49/62, confluent B-lines in 38/62, and separate B-lines in 34/62, consolidation in 12/62, C prime profile in 19/62, and pleural and cardiac effusions in 4/62 and 1/62, respectively. The singl...

Background Spontaneous pneumomediastinum, pneumothorax and spontaneous subcutaneous emphysema are... more Background Spontaneous pneumomediastinum, pneumothorax and spontaneous subcutaneous emphysema are rare entities. A rising trend in the setting of COVID-19 even in patients who are not put on invasive ventilation can suggest an alternative aetiology. Case presentation We describe four cases which presented with suspected symptoms of COVID-19 and were diagnosed with pneumomediastinum, pneumothorax, and subcutaneous emphysema which would have been missed if not for computed tomography scan performed at the time of admission. Three of these cases had no prior history of any iatrogenic intervention, and the fourth person developing pneumothorax and subcutaneous emphysema after intubation. Conclusions Pneumomediastinum, pneumothorax and subcutaneous emphysema can be noted as a complication of COVID-19 itself as well as the complication of management of COVID-19.

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2021

Introduction: Novel Coronavirus-2019 (nCoV-2019) is capable of human-to-human transmission and ca... more Introduction: Novel Coronavirus-2019 (nCoV-2019) is capable of human-to-human transmission and can lead to acute respiratory distress syndrome similar to Middle East Respiratory Syndrome (MERS) due to lung parenchyma destruction. Some patients with COVID-19 consistently demonstrated no hypoxaemia, however, some patients develop sense of difficulty in breathing due to increased airway resistance. Aim: To assess the potential of High Resolution Computed Tomography (HRCT) thorax as an early predictor of hypoxaemia in COVID-19 patients. Materials and Methods: A prospective longitudinal cohort study of 1000 Reverse Transcription Polymerase Chain Reaction (RT-PCR) confirmed COVID-19 and HRCT thorax positive patients, who were monitored simultaneously for SpO2 levels, were undertaken. HRCT findings were graded into Computerised Tomography Severity Index (CTSI) and correlated with patient’s SpO2 levels, at the time of scan on admission. Patients, who had normal SpO2 levels (≥95%) at the tim...

Indian Journal of Musculoskeletal Radiology, 2021

We present a case report and review the literature on Hajdu Cheney syndrome (HCS), an extremely r... more We present a case report and review the literature on Hajdu Cheney syndrome (HCS), an extremely rare connective tissue disorder with <100 cases reported in the last 72 years. We have emphasized on the patterns of acro-osteolysis (acrosteolysis) in the literature review to conclude if the syndrome follows any particular pattern like in our case. All major databases were searched for all cases of HCS. One hundred and eighty-eight hand radiographs were analyzed and detailed analysis of all digits was carried out with emphasis on the pattern of acrosteolysis. Acrosteolysis may not be a mandatory association in HCS as 18.8% did not have acrosteolysis at all. The first finger to be involved in 90/96 (93.7%) of the cases was the index finger, followed by the middle finger and then the thumb. The 4th digit (ring finger) was involved in only 11/96 (11.4%) of the cases, of which 9/11 (81.8%) were above the age of 25. Incidence of acrosteolysis of the 4th digit when in comparison to all oth...

Indian journal of respiratory care, 2022

After almost 2 years of the coronavirus disease epidemic, the mortality is staggeringly higher, a... more After almost 2 years of the coronavirus disease epidemic, the mortality is staggeringly higher, at over 10 million. [1] Fortunately, there are a number of effective vaccinations available now that might aid in the containment of the coronavirus disease-2019 (COVID-19) epidemic. However, our vaccination efforts must battle the rapidly increasing severe acute respiratory syndrome coronavirus (SARS-CoV-2) strains, which are a huge problem. SARS-CoV-2 has developed into new fatal strains than their predecessors, the most dangerous of which is the delta type. These mutations are worrisome due to their higher chances of transmission, symptom severity, and immune evasion, creating a risk of reinfection in convalescents or breakthrough infections in vaccinated people. [2] To limit the epidemic, which has had severe medical, economic, and societal implications, safe and efficient preventive vaccinations are required even though some are still getting infected during postvaccination status. This research aims to investigate the limits and extents of pulmonary involvement in vaccinated patients of COVID-19 and the relationship between vaccination status and lung severity. Two vaccines were developed in India at the time of this research, both of which required two doses and a booster for full immunization. [3] Methods We retrospectively analyzed our COVID-19-related high-resolution computed tomography (HRCT) of thorax data from April to August 2021. This was done to identify positive patients on reverse transcription-polymerase chain reaction (RT-PCR) who have undergone a HRCT of the thorax to analyze the extent of pulmonary involvement by applying the computed tomography severity score (CTSS).

The Neuroradiology Journal

Pituitary gland duplication is a rare abnormality and isolated duplication of the pituitary stalk... more Pituitary gland duplication is a rare abnormality and isolated duplication of the pituitary stalk without any pituitary anomaly is an even rarer entity with this case being the first documented case till date. Although incidentally discovered cases of duplication of pituitary gland (DPG) have been reported, sometimes with a duplicated pituitary stalk, patients with this disorder usually present with other craniofacial abnormalities. Consequently, DPG plus syndrome is used as it is often accompanied by endocrine disturbances and pathologies such as median cleft face syndrome, ocular disorders, craniocervical bony abnormalities, vascular anomalies and tuberomammillary masses. Since this is the first reported case without any additional pituitary gland anomaly, we propose the acronym DPS (duplication of pituitary stalk) to be used to unify this entity as we are certain that much like the previously described pituitary duplication disorders, more cases will be documented independently r...

Indian Journal of Respiratory Care

After almost 2 years of the coronavirus disease epidemic, the mortality is staggeringly higher, a... more After almost 2 years of the coronavirus disease epidemic, the mortality is staggeringly higher, at over 10 million. [1] Fortunately, there are a number of effective vaccinations available now that might aid in the containment of the coronavirus disease-2019 (COVID-19) epidemic. However, our vaccination efforts must battle the rapidly increasing severe acute respiratory syndrome coronavirus (SARS-CoV-2) strains, which are a huge problem. SARS-CoV-2 has developed into new fatal strains than their predecessors, the most dangerous of which is the delta type. These mutations are worrisome due to their higher chances of transmission, symptom severity, and immune evasion, creating a risk of reinfection in convalescents or breakthrough infections in vaccinated people. [2] To limit the epidemic, which has had severe medical, economic, and societal implications, safe and efficient preventive vaccinations are required even though some are still getting infected during postvaccination status. This research aims to investigate the limits and extents of pulmonary involvement in vaccinated patients of COVID-19 and the relationship between vaccination status and lung severity. Two vaccines were developed in India at the time of this research, both of which required two doses and a booster for full immunization. [3] Methods We retrospectively analyzed our COVID-19-related high-resolution computed tomography (HRCT) of thorax data from April to August 2021. This was done to identify positive patients on reverse transcription-polymerase chain reaction (RT-PCR) who have undergone a HRCT of the thorax to analyze the extent of pulmonary involvement by applying the computed tomography severity score (CTSS).

Indian Journal of Radiology and Imaging

Background The information-seeking behavior of the radiology residents on call has undergone mode... more Background The information-seeking behavior of the radiology residents on call has undergone modernization in the recent times given the advent of easy to access, reliable online resources, and robust artificial intelligence chatbots such as Chat Generative Pre-Trained Transformer (ChatGPT). Purpose The aim of this study was to conduct a baseline analysis among the residents to understand the best way to meet information needs in the future, spread awareness about the existing resources, and narrow down to the most preferred online resource. Methods and Materials A prospective, descriptive study was performed using an online survey instrument and was conducted among radiology residents in India. They were questioned on their demographics, frequency of on call, fatigue experienced on call, and preferred information resources and reasons for choosing them. Results A total of 286 residents participated in the survey. All residents had used the Internet radiology resources during on-cal...

The Egyptian Journal of Radiology and Nuclear Medicine, 2021

Background There has been a rapid rise in the number of COVID-19-associated rhino-orbital mucormy... more Background There has been a rapid rise in the number of COVID-19-associated rhino-orbital mucormycosis (CAROM) cases especially in South Asian countries, to an extent that it has been considered an epidemic among the COVID-19 patients in India. As of May 13, 2021, 101 CAROM cases have been reported, of which 82 cases were from India and 19 from the rest of the world. On the other hand, pulmonary mucormycosis associated with COVID-19 has a much lesser reported incidence of only 7% of the total COVID-19-associated mucormycosis cases (Singh AK, Singh R, Joshi SR, Misra A, Diab Metab Syndr: Clin Res Rev, 2021). This case report attempts to familiarize the health care professionals and radiologists with the imaging findings that should alarm for follow-up and treatment in the lines of CAROM. Case presentation Rhino-orbital mucormycosis (ROM) is a manifestation of mucormycosis that is thought to be acquired by inhalation of fungal spores into the paranasal sinuses. Here, we describe a 55-...

The Egyptian Journal of Radiology and Nuclear Medicine, 2021

Background High-resolution computed tomography (HRCT) chest becomes a valuable diagnostic tool fo... more Background High-resolution computed tomography (HRCT) chest becomes a valuable diagnostic tool for identifying patients infected with Coronavirus Disease 2019 (COVID-19) in the early stage, where patients may be asymptomatic or with non-specific pulmonary symptoms. An early diagnosis of COVID-19 is of utmost importance, so that patients can be isolated and treated in time, eventually preventing spread of the disease, improving the prognosis and reducing the mortality. In this paper, we have highlighted our radiological experience of dealing with the pandemic crisis of 2020 through the study of HRCT thorax, lung ultrasonography, chest X-rays and artificial intelligence (AI). Results Results of CT thorax analysis have been given in detail. We had also compared CT severity score (CTSS) with clinical and laboratory parameters. Correlation of CTSS with SpO2 values and comorbidities was also studied. We also analysed manual CTSS with the CTSS scored calculated by the AI software. Conclusi...

Background: The objectives were to perform an analysis of lung ultrasonography (LUS) findings in ... more Background: The objectives were to perform an analysis of lung ultrasonography (LUS) findings in severely ill patients with novel coronavirus disease-2019 (COVID-19) and to compare the accuracy with high-resolution computed tomography (HRCT) of the thorax. Methods: Sixty-two intensive care unit (ICU) patients with COVID-19 were evaluated during their hospital stay. LUS was performed with convex and linear transducers using a designated ultrasonography machine placed in the COVID-19 ICU. The thorax was scanned in 12 areas. Initial LUS was performed on admission and follow-up LUS was done in 7 (mean) days. At the time of the initial LUS, HRCT was performed in 28/62 patients and a chest radiography in 19/62 patients. Results: On admission, LUS detected pleural line thickening (>6 lung areas) in 49/62, confluent B-lines in 38/62, and separate B-lines in 34/62, consolidation in 12/62, C prime profile in 19/62, and pleural and cardiac effusions in 4/62 and 1/62, respectively. The singl...

Background Spontaneous pneumomediastinum, pneumothorax and spontaneous subcutaneous emphysema are... more Background Spontaneous pneumomediastinum, pneumothorax and spontaneous subcutaneous emphysema are rare entities. A rising trend in the setting of COVID-19 even in patients who are not put on invasive ventilation can suggest an alternative aetiology. Case presentation We describe four cases which presented with suspected symptoms of COVID-19 and were diagnosed with pneumomediastinum, pneumothorax, and subcutaneous emphysema which would have been missed if not for computed tomography scan performed at the time of admission. Three of these cases had no prior history of any iatrogenic intervention, and the fourth person developing pneumothorax and subcutaneous emphysema after intubation. Conclusions Pneumomediastinum, pneumothorax and subcutaneous emphysema can be noted as a complication of COVID-19 itself as well as the complication of management of COVID-19.

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2021

Introduction: Novel Coronavirus-2019 (nCoV-2019) is capable of human-to-human transmission and ca... more Introduction: Novel Coronavirus-2019 (nCoV-2019) is capable of human-to-human transmission and can lead to acute respiratory distress syndrome similar to Middle East Respiratory Syndrome (MERS) due to lung parenchyma destruction. Some patients with COVID-19 consistently demonstrated no hypoxaemia, however, some patients develop sense of difficulty in breathing due to increased airway resistance. Aim: To assess the potential of High Resolution Computed Tomography (HRCT) thorax as an early predictor of hypoxaemia in COVID-19 patients. Materials and Methods: A prospective longitudinal cohort study of 1000 Reverse Transcription Polymerase Chain Reaction (RT-PCR) confirmed COVID-19 and HRCT thorax positive patients, who were monitored simultaneously for SpO2 levels, were undertaken. HRCT findings were graded into Computerised Tomography Severity Index (CTSI) and correlated with patient’s SpO2 levels, at the time of scan on admission. Patients, who had normal SpO2 levels (≥95%) at the tim...

Indian Journal of Musculoskeletal Radiology, 2021

We present a case report and review the literature on Hajdu Cheney syndrome (HCS), an extremely r... more We present a case report and review the literature on Hajdu Cheney syndrome (HCS), an extremely rare connective tissue disorder with <100 cases reported in the last 72 years. We have emphasized on the patterns of acro-osteolysis (acrosteolysis) in the literature review to conclude if the syndrome follows any particular pattern like in our case. All major databases were searched for all cases of HCS. One hundred and eighty-eight hand radiographs were analyzed and detailed analysis of all digits was carried out with emphasis on the pattern of acrosteolysis. Acrosteolysis may not be a mandatory association in HCS as 18.8% did not have acrosteolysis at all. The first finger to be involved in 90/96 (93.7%) of the cases was the index finger, followed by the middle finger and then the thumb. The 4th digit (ring finger) was involved in only 11/96 (11.4%) of the cases, of which 9/11 (81.8%) were above the age of 25. Incidence of acrosteolysis of the 4th digit when in comparison to all oth...