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URL: https://web.expasy.org/cellosaurus/CVCL_0019

Proper Citation: (RRID:CVCL_0019)

Description: Cell line SH-SY5Y is a Cancer cell line with a species of origin Homo sapiens (Human)

Sex: Female

Defining Citation: PMID:1354203, PMID:2535691, PMID:2846152, PMID:3968181, PMID:4748425, PMID:6137586, PMID:7687927, PMID:10630978, PMID:11668190, PMID:12505268, PMID:14676279, PMID:15150091, PMID:15720811, PMID:16120276, PMID:16822308, PMID:17506115, PMID:18957096, PMID:20655465, PMID:22213050, PMID:22460905, PMID:23421552, PMID:24466371, PMID:25182563, PMID:25730103, PMID:25884760, PMID:26342562, PMID:26972028, PMID:27141528, PMID:28118852, PMID:28350380, PMID:28601559, PMID:29468137, PMID:30894373, PMID:31068700

Comments: Omics: Transcriptome analysis by RNAseq., Omics: Transcriptome analysis by microarray., Omics: SNP array analysis., Omics: N-glycan profiling., Omics: Mitochondrial proteome analysis by 2D-DE/MS., Omics: GPI-anchored proteins analysis by proteomics., Omics: Deep tyrosine phosphoproteome analysis., Omics: Deep proteome analysis., Omics: Deep exome analysis., Omics: Deep antibody staining analysis., Virology: Low susceptibility to infection by Zika virus (ZIKV) (PubMed=29468137)., Characteristics: There seem to be differences in the retinoic acid (RA)-induced neuronal phenotype of SH-SY5Y cells from ATCC and ECACC. After 5 days of RA treatment, ECACC cells are slightly larger in size and contains significant amount of neuroblastic (N-type) cells and a small fraction of epithelial (S-type) cells (PubMed=18957096)., Characteristics: Neuroblastic type (N-type) (PubMed=15720811)., Population: Caucasian., From: Memorial Sloan Kettering Cancer Center; New York; USA., Part of: ENCODE project common cell types; tier 3., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Partially contaminated. Some laboratories that are redistributing this cell line are in fact redistributing a contaminated cell line of mouse origin (PubMed=25182563)..

Category: Cancer cell line

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Name: SH-SY5Y

Synonyms: SH-Sy5y, SHSY5Y, SHSY-5Y, SK-SH-SY5Y, SY5Y, SH-SY5Y Parental

Cross References: BTO:BTO_0000793, CLO:CLO_0009015, EFO:EFO_0002717, MCCL:MCC:0000421, CLDB:cl4287, CLDB:cl4288, CLDB:cl4289, CLDB:cl4290, Abcam:ab275475, AddexBio:C0005004/63, ATCC:CRL-2266, BCRJ:0223, BioGRID_ORCS_Cell_line:1228, BioSample:SAMN10987717, cancercelllines:CVCL_0019, CancerTools:161932, CCRID:1101HUM-PUMC000026, CCRID:3101HUMSCSP5014, CCRID:3101HUMTCHu97, CCRID:4201PAT-CCTCC00086, CCRID:4201HUM-CCTCC00210, CCRID:5301HUM-KCB06107YJ, CCTCC:GDC0210, Cell_Model_Passport:SIDM01236, CGH-DB:63-1, ChEMBL-Cells:CHEMBL3307740, ChEMBL-Targets:CHEMBL614910, CLS:300154, Cosmic:688084, Cosmic:1019933, Cosmic:1167410, Cosmic:1212536, Cosmic:2058109, Cosmic:2239470, Cosmic:2393641, DepMap:ACH-001188, DSMZ:ACC-209, DSMZCellDive:ACC-209, ECACC:94030304, ENCODE:ENCBS264AAA, GEO:GSM231608, GEO:GSM231609, GEO:GSM231610, GEO:GSM231611, GEO:GSM231612, GEO:GSM231613, GEO:GSM231614, GEO:GSM231615, GEO:GSM231616, GEO:GSM231617, GEO:GSM231618, GEO:GSM231619, GEO:GSM231620, GEO:GSM231621, GEO:GSM231622, GEO:GSM231623, GEO:GSM231624, GEO:GSM231625, GEO:GSM231626, GEO:GSM231627, GEO:GSM231628, GEO:GSM231629, GEO:GSM231630, GEO:GSM231631, GEO:GSM231632, GEO:GSM231633, GEO:GSM231634, GEO:GSM231635, GEO:GSM231636, GEO:GSM231637, GEO:GSM231638, GEO:GSM231639, GEO:GSM231640, GEO:GSM231641, GEO:GSM231642, GEO:GSM231643, GEO:GSM231644, GEO:GSM231645, GEO:GSM231646, GEO:GSM231647, GEO:GSM231648, GEO:GSM231649, GEO:GSM231650, GEO:GSM231651, GEO:GSM231652, GEO:GSM231653, GEO:GSM231654, GEO:GSM231655, GEO:GSM231656, GEO:GSM231657, GEO:GSM231658, GEO:GSM231659, GEO:GSM231660, GEO:GSM231661, GEO:GSM231662, GEO:GSM231663, GEO:GSM231664, GEO:GSM231665, GEO:GSM231666, GEO:GSM231667, GEO:GSM231668, GEO:GSM231669, GEO:GSM231670, GEO:GSM231671, GEO:GSM231672, GEO:GSM231673, GEO:GSM692874, GEO:GSM887570, GEO:GSM888653, GEO:GSM1622294, GEO:GSM2371253, GEO:GSM2394368, IARC_TP53:23599, ICLC:HTL95013, IZSLER:BS TCL 232, KCB:KCB 2006107YJ, KCLB:22266, Kerafast:ECP004, LINCS_LDP:LCL-2000, Lonza:132, MetaboLights:MTBLS455, NCBI_Iran:C611, PharmacoDB:SHSY5Y_1374_2019, PRIDE:PXD003105, PRIDE:PXD003914, PRIDE:PXD004452, PRIDE:PXD010005, PRIDE:PXD010027, PRIDE:PXD010776, PRIDE:PXD014381, PRIDE:PXD020389, PRIDE:PXD029012, Progenetix:CVCL_0019, PubChem_Cell_line:CVCL_0019, TOKU-E:3118, Ubigene:YC-D014, Wikidata:Q7390126

ID: CVCL_0019

Hierarchy: CVCL_0531

Record Creation Time: 2022-04-27 03:15:40

Record Last Update: 2024-12-20 12:08:15

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