Generation of both cortical and Aire⁺ medullary thymic epithelial compartments from CD205⁺ progenitors (original) (raw)

“…-2875 that CCRL1 + fetal cTECs contain mTEC progenitor activity. These results agree with the recent reports discussed above showing that pTECs progress through a stage in which they express cTECassociated molecules before diversifying into mTECs [11,[14][15][16] (Fig. 1).…”

Section: Cortical Thymic Epithelial Cells (Ctecs) and Medullary Thymisupporting

See 4 more Smart Citations

“…-2875 that CCRL1 + fetal cTECs contain mTEC progenitor activity. These results agree with the recent reports discussed above showing that pTECs progress through a stage in which they express cTECassociated molecules before diversifying into mTECs [11,[14][15][16] (Fig. 1).…”

Section: Cortical Thymic Epithelial Cells (Ctecs) and Medullary Thymisupporting

“…Revealing the mechanisms that underlie the specific expression of these molecules among the different TEC subpopulations would be useful to understand the molecular and cellular mechanisms for the diversification of TEC subpopulations. Along these lines, recent experiments have shown that mTECs are derived from progenitors that express cTEC-associated molecules [14][15][16]. Baik et al showed that the expression of CD205 in a fraction of TECs was detectable in embryonic day 11 (E11) mouse embryos ([14]; commented on in [17]).…”

mentioning

See 3 more Smart Citations