Vitamin D — Effects on Skeletal and Extraskeletal Health and the Need for Supplementation (original) (raw)

“…Cholecalciferol and ergocalciferol (vitamin D 2 ) can be obtained from the diet as well. In humans, both cholecalciferol and ergocalciferol are sequentially transformed into 25-hydroxyvitamin D 3 [25(OH)D], 25-hydroxycholecalciferol, or calcidiol, in the liver, which are subsequently transformed in kidneys and other tissues into 1,25-dihydroxyvitamin D 3 [1,25(OH)2D], 1,25-dihydroxycholecalciferol or calcitriol (1)(2)(3).…”