Race and gender variation in response to evoked inflammation (original) (raw)

“…The protocol was approved by the University of Pennsylvania Institutional Review Board, had regulatory oversight by the US Food and Drug Administration (LPS: IND 5,984), and was monitored by a National Institute of Health-appointed data safety and monitoring board. Subjects in GENE were admitted to the clinical translational research center inpatient unit for administration of intravenous endotoxin (LPS; 1 ng/kg) and were monitored closely as described (27). Serial blood draws were collected immediately before and 1, 2, 4, 6, 12, and 24 hours post-LPS for plasma.…”