Lutein/Zeaxanthin for the Treatment of Age-Related Cataract (original) (raw)

“…More than 4000 people at the age of 73.1 meanly divided four treatment groups; placebo, lutein/zeaxanthin, DHA/EPA, lutein/zeaxanthin+DHA/EPA. In contrast to the other studies, this placebo-controlled, randomized study indicated that lutein and zeaxanthin supplementation had no significant beneficial or adverse effects on cataract surgery, any type of cataract and losing sight [73]. …”

Section: Role Of Lutein and Zeaxanthin In Cataractcontrasting

“…More than 4000 people at the age of 73.1 meanly divided four treatment groups; placebo, lutein/zeaxanthin, DHA/EPA, lutein/zeaxanthin+DHA/EPA. In contrast to the other studies, this placebo-controlled, randomized study indicated that lutein and zeaxanthin supplementation had no significant beneficial or adverse effects on cataract surgery, any type of cataract and losing sight [73]. …”

Section: Role Of Lutein and Zeaxanthin In Cataractcontrasting

“…No discussion of our findings would be complete without reference to the recently published AREDS2 reports, 62,63 where analysis of secondary outcomes indicated a benefit of supplementation with L and Z, in terms of AMD progression and preservation of vision, especially in subjects with low dietary intake of those two carotenoids. Given that only two of the three macular carotenoids were used in AREDS2, our findings are rendered all the more clinically meaningful, if not somewhat provocative.…”

Section: Discussionmentioning

“…Substitution of lutein and zeaxanthin for β-carotene, which may have adverse effects on patients with a smoking history, was recommended based on the AREDS2 data. None of the formulations had an impact on the incidence or progression of atrophic AMD (15).…”

Section: Oxidative Stressmentioning