MIND diet associated with reduced incidence of Alzheimer's disease (original) (raw)

“…The “MIND-diet,” which incorporates elements of both the Mediterranean diet and the “DASH diet,” has been linked with a lower risk of cognitive impairment 91 and the development of AD. 92 It is recognized that association in epidemiological studies does not prove causality. The FINGER and PREDIMED-NAVARRA studies were controlled interventional studies, helping to confirm causality.…”

Section: Potential Benefits Of Early Diagnosis Of Cognitive Impairmentmentioning

“…Certain diets show promising, preventive effects on brain aging and cognitive impairment in observational studies and in clinical trials [1–3]. Higher adherence to the Mediterranean diet (MeDi) is associated with a lower risk for AD [4–8]. Prospectively, we showed that a high percentage of daily calories derived from protein and fat were associated with a reduced risk of incident MCI, whereas a high percentage from carbohydrates was associated with an increased risk of incident MCI [9].…”

Section: Introductionmentioning

“…The Mediterranean diet [113], exercise [114] and caloric restriction [115,116] have been shown to modulate AD risk factors including the mitochondrial healthy homeostasis. In combination with these, several preventive approaches have been studied in AD patients, for example the antioxidant N-acetyl cysteine (NAC) [117], α-lipoic acid (LA) [118] and curcumin [119] have been tested.…”

Section: Therapeutic Approaches Targeted To Modulation Of Mitochondrimentioning