Cytopathology of the uterine cervix (original) (raw)

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Histopathology and Cytopathology of the Uterine Cervix - Digital Atlas

IARC CancerBase No. 8

Edited by Frappart L, Fontaniere B, Lucas E, Sankaranarayanan R

2004

ISBN-13 (Database)

978-92-832-2424-2

Histopathology and Cytopathology of the Uterine Cervix - Digital Atlas

IARC CancerBase No. 8

Edited by Frappart L, Fontaniere B, Lucas E, Sankaranarayanan R

2004

ISBN-13 (Database)

978-92-832-2424-2

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Cytopathology of the uterine cervix - digital atlas

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Material & Methods

Bethesda 2001 system

Unsatisfactory specimen

Sampling & preparation methods

Smear sampling/slide preparation for conventional cytology

Smear sampling/slide preparation for liquid-based cytology

Staining and mounting

Conventional preparation

Liquid-based preparation

Normal cells

Normal squamous cells

Normal endocervical glandular cells

Normal endocervical glandular cells: columnar

Normal endocervical glandular cells: secretory

Normal endocervical glandular cells: ciliated

Normal endometrial glandular cells

Squamous metaplasia

Mature squamous metaplasia

Immature squamous/transitional metaplasia

Histiocytes and inflammatory cells

Benign cellular modifications

Specific inflammations

Trichomonas vaginalis

Mycosis: Candida

Vaginal bacteriosis

Actinomyces

Herpes

Parasites

Other non-neoplastic findings

Inflammation and repair

Radiation-induced changes

IUD associated changes

Atrophy

Glandular cells after radical hysterectomy

Parakeratosis

Hyperkeratosis (leukoplakia)

Lymphofollicular cervicitis

Other (endometrial cells after 40 years)

Abnormalities of squamous cells

Atypical squamous cells (ASC)

ASC of undetermined significance (ASC-US)

ASC-USASC-US, yes or no?ASC-US suggesting a LSIL

ASC cannot exclude a high-grade lesion (ASC-H)

ASC-HASC-H or HSIL?

Low-grade Squamous Intraepithelial Lesion (LSIL)

High-grade Squamous Intraepithelial Lesion (HSIL)

LSIL or HSIL?

HSIL

HSIL with features suspicious of invasion

Squamous cell carcinoma

Abnormalities of glandular cells

Atypia of glandular cells (AGC)

Adenocarcinoma in situ (AIS)

Invasive adenocarcinoma

Other malignant lesions

Endometrial adenocarcinoma

Malignant lymphoma

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