Meran Mostafa | Suez Canal University (original) (raw)

Papers by Meran Mostafa

Research paper thumbnail of Impact of Degeneration of the Prelimbic and Infralimbic Cortices on Psychomotor Activity and Cognitive Function in Rats Stereotaxically Injected with Ibotenate

Background: Little is understood about how mild cognitive impairment affects motor function (MCI)... more Background: Little is understood about how mild cognitive impairment affects motor function (MCI). Memory and psychomotor functions are assumed to be regulated by the medial prefrontal cortex (mPFC). The mPFC consists of a total of three distinct subareas. Thus, the purpose of this work was to specifically damage the prelimbic (PrL) and infralimbic (IFL) subareas utilizing a rodent stereotaxis injection of a relatively low dose of ibotenate. Aim: to investigate the impact of the PrL and IFL subareas lesions on psychomotor activities and memory among stereotaxically injected rats with ibotenate. Materials and Methods: For this study, a total of 36 white albino rats were employed. Three groups were designed: the normal control group (GI), the bilateral sham group (GII) which included injected rats with phosphate-buffered saline (PBS) in the PrL and IL subareas, and the bilateral lesioned group (GIII) which included injected rats with ibotenate in the PrL and IL cortices. Then rats were undergone through the open field test (OFT) and hole board test (HB). Transcardial perfusion and brain extraction for tissue preparation and histological evaluation were done at the end of the experiment. Results: the group with bilateral PrL and IFL lesions had intact psychomotor functions and spatial reference memory, but they started to lose short-term memory. Conclusions: PrL and IFL subareas of the mPFC degeneration don't impair psychomotor functions or spatial reference memory but can impact short-term memory in rats.

Research paper thumbnail of Impact of Degeneration of the Prelimbic and Infralimbic Cortices on Psychomotor Activity and Cognitive Function in Rats Stereotaxically Injected with Ibotenate

Background: Little is understood about how mild cognitive impairment affects motor function (MCI)... more Background: Little is understood about how mild cognitive impairment affects motor function (MCI). Memory and psychomotor functions are assumed to be regulated by the medial prefrontal cortex (mPFC). The mPFC consists of a total of three distinct subareas. Thus, the purpose of this work was to specifically damage the prelimbic (PrL) and infralimbic (IFL) subareas utilizing a rodent stereotaxis injection of a relatively low dose of ibotenate. Aim: to investigate the impact of the PrL and IFL subareas lesions on psychomotor activities and memory among stereotaxically injected rats with ibotenate. Materials and Methods: For this study, a total of 36 white albino rats were employed. Three groups were designed: the normal control group (GI), the bilateral sham group (GII) which included injected rats with phosphate-buffered saline (PBS) in the PrL and IL subareas, and the bilateral lesioned group (GIII) which included injected rats with ibotenate in the PrL and IL cortices. Then rats were undergone through the open field test (OFT) and hole board test (HB). Transcardial perfusion and brain extraction for tissue preparation and histological evaluation were done at the end of the experiment. Results: the group with bilateral PrL and IFL lesions had intact psychomotor functions and spatial reference memory, but they started to lose short-term memory. Conclusions: PrL and IFL subareas of the mPFC degeneration don't impair psychomotor functions or spatial reference memory but can impact short-term memory in rats.

Research paper thumbnail of Evaluation of impact of Problem Based Learning upon 4th & 6th year student's skills  In Faculty of Medicine Suez Canal University

Evaluation of impact of Problem Based Learning upon 4th & 6th year student's skills In Faculty of Medicine Suez Canal University

Authors : Meran Moustafa, Amat-AlRahman Mohamed, Marwa Magde , Klara Emad , Aya Elsayed Nofal ... more Authors : Meran Moustafa, Amat-AlRahman Mohamed, Marwa Magde , Klara Emad , Aya Elsayed Nofal ,Sara Mohamed Hassan , Soad Mamdouh , Soha Kamal , Ahmed Atef , Omar Mohammed El-swefi, Mohammed Alaa El-degidy,
Dr. Mohamed Alaa Abdel Hamid, Dr. Yasser Mohamed Youssef, Prof. Dr. Moustafa Foad Abass Kofi

Faculty of medicine Suez Canal University is the only medical college in Egypt that adopts problem-based learning as a teaching method. The goals of PBL are to help the students develop flexible knowledge, effective problem solving skills, self-directed learning, effective collaboration skills and intrinsic motivation. Problem-based learning is a style of active learning. and The PBL curriculum was developed in order to stimulate the learners, assist the learners in seeing the relevance of learning to future roles, maintain a higher level of motivation towards learning, and to show the learners the importance of responsible, professional attitudedes
The goal of the study was to Evaluation of impact of Problem Based Learning upon 4th & 6th year student's skills in Faculty of Medicine Suez Canal University. It aimed at enhancing the student's motivation to learn on his\her own and to have maximum benefits from problem solving self-learning.and determine the most important barriers between students and the maximum benefit from the Problem –based learning teaching system
The study was conducted on 107 medical student through across sectional survey .Data was collected through an interviewer administrated questionnaire.
Key words : problem based learning , student's skill , faculty of medicine Suez canal university

Research paper thumbnail of Impact of Degeneration of the Prelimbic and Infralimbic Cortices on Psychomotor Activity and Cognitive Function in Rats Stereotaxically Injected with Ibotenate

Background: Little is understood about how mild cognitive impairment affects motor function (MCI)... more Background: Little is understood about how mild cognitive impairment affects motor function (MCI). Memory and psychomotor functions are assumed to be regulated by the medial prefrontal cortex (mPFC). The mPFC consists of a total of three distinct subareas. Thus, the purpose of this work was to specifically damage the prelimbic (PrL) and infralimbic (IFL) subareas utilizing a rodent stereotaxis injection of a relatively low dose of ibotenate. Aim: to investigate the impact of the PrL and IFL subareas lesions on psychomotor activities and memory among stereotaxically injected rats with ibotenate. Materials and Methods: For this study, a total of 36 white albino rats were employed. Three groups were designed: the normal control group (GI), the bilateral sham group (GII) which included injected rats with phosphate-buffered saline (PBS) in the PrL and IL subareas, and the bilateral lesioned group (GIII) which included injected rats with ibotenate in the PrL and IL cortices. Then rats were undergone through the open field test (OFT) and hole board test (HB). Transcardial perfusion and brain extraction for tissue preparation and histological evaluation were done at the end of the experiment. Results: the group with bilateral PrL and IFL lesions had intact psychomotor functions and spatial reference memory, but they started to lose short-term memory. Conclusions: PrL and IFL subareas of the mPFC degeneration don't impair psychomotor functions or spatial reference memory but can impact short-term memory in rats.

Research paper thumbnail of Impact of Degeneration of the Prelimbic and Infralimbic Cortices on Psychomotor Activity and Cognitive Function in Rats Stereotaxically Injected with Ibotenate

Background: Little is understood about how mild cognitive impairment affects motor function (MCI)... more Background: Little is understood about how mild cognitive impairment affects motor function (MCI). Memory and psychomotor functions are assumed to be regulated by the medial prefrontal cortex (mPFC). The mPFC consists of a total of three distinct subareas. Thus, the purpose of this work was to specifically damage the prelimbic (PrL) and infralimbic (IFL) subareas utilizing a rodent stereotaxis injection of a relatively low dose of ibotenate. Aim: to investigate the impact of the PrL and IFL subareas lesions on psychomotor activities and memory among stereotaxically injected rats with ibotenate. Materials and Methods: For this study, a total of 36 white albino rats were employed. Three groups were designed: the normal control group (GI), the bilateral sham group (GII) which included injected rats with phosphate-buffered saline (PBS) in the PrL and IL subareas, and the bilateral lesioned group (GIII) which included injected rats with ibotenate in the PrL and IL cortices. Then rats were undergone through the open field test (OFT) and hole board test (HB). Transcardial perfusion and brain extraction for tissue preparation and histological evaluation were done at the end of the experiment. Results: the group with bilateral PrL and IFL lesions had intact psychomotor functions and spatial reference memory, but they started to lose short-term memory. Conclusions: PrL and IFL subareas of the mPFC degeneration don't impair psychomotor functions or spatial reference memory but can impact short-term memory in rats.

Research paper thumbnail of Evaluation of impact of Problem Based Learning upon 4th & 6th year student's skills  In Faculty of Medicine Suez Canal University

Evaluation of impact of Problem Based Learning upon 4th & 6th year student's skills In Faculty of Medicine Suez Canal University

Authors : Meran Moustafa, Amat-AlRahman Mohamed, Marwa Magde , Klara Emad , Aya Elsayed Nofal ... more Authors : Meran Moustafa, Amat-AlRahman Mohamed, Marwa Magde , Klara Emad , Aya Elsayed Nofal ,Sara Mohamed Hassan , Soad Mamdouh , Soha Kamal , Ahmed Atef , Omar Mohammed El-swefi, Mohammed Alaa El-degidy,
Dr. Mohamed Alaa Abdel Hamid, Dr. Yasser Mohamed Youssef, Prof. Dr. Moustafa Foad Abass Kofi

Faculty of medicine Suez Canal University is the only medical college in Egypt that adopts problem-based learning as a teaching method. The goals of PBL are to help the students develop flexible knowledge, effective problem solving skills, self-directed learning, effective collaboration skills and intrinsic motivation. Problem-based learning is a style of active learning. and The PBL curriculum was developed in order to stimulate the learners, assist the learners in seeing the relevance of learning to future roles, maintain a higher level of motivation towards learning, and to show the learners the importance of responsible, professional attitudedes
The goal of the study was to Evaluation of impact of Problem Based Learning upon 4th & 6th year student's skills in Faculty of Medicine Suez Canal University. It aimed at enhancing the student's motivation to learn on his\her own and to have maximum benefits from problem solving self-learning.and determine the most important barriers between students and the maximum benefit from the Problem –based learning teaching system
The study was conducted on 107 medical student through across sectional survey .Data was collected through an interviewer administrated questionnaire.
Key words : problem based learning , student's skill , faculty of medicine Suez canal university