Risk of bias tools - RoB 2 tool (original) (raw)

A revised tool to assess risk of bias in randomized trials (RoB 2)

Welcome to the website for the RoB 2 tool.

The current version (22 August 2019), suitable for individually-randomized, parallel-group trials.

NEW! A test version for cluster-randomized trials is now available (10 November 2020, revised 18 March 2021).

NEW! A test version for crossover trials is now available (8 December 2020, revised 18 March 2021).

We are also maintaining an archive of the previous version, which had variants for three different trial designs (see below).

The revised tool may be cited as:

Sterne JAC, Savović J, Page MJ, Elbers RG, Blencowe NS, Boutron I, Cates CJ, Cheng H-Y, Corbett MS, Eldridge SM, Hernán MA, Hopewell S, Hróbjartsson A, Junqueira DR, Jüni P, Kirkham JJ, Lasserson T, Li T, McAleenan A, Reeves BC, Shepperd S, Shrier I, Stewart LA, Tilling K, White IR, Whiting PF, Higgins JPT. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ 2019; 366: l4898.

Higgins JPT, Sterne JAC, Savović J, Page MJ, Hróbjartsson A, Boutron I, Reeves B, Eldridge S. A revised tool for assessing risk of bias in randomized trials In: Chandler J, McKenzie J, Boutron I, Welch V (editors). Cochrane Methods. Cochrane Database of Systematic Reviews 2016, Issue 10 (Suppl 1). dx.doi.org/10.1002/14651858.CD201601.