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Address: Kuala Lumpur, Kuala Lumpur, Malaysia

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Papers by Alice Chew

... ETM+ data: Possibilities and limitations Alice Wang-Cheng Heng, Soo Chin Liew and Chew Wai Ch... more ... ETM+ data: Possibilities and limitations Alice Wang-Cheng Heng, Soo Chin Liew and Chew Wai Chang Centre for Remote Imaging, Sensing and Processing The National University of Singapore 10 Kent Ridge Cresent Singapore 119260 ...

PLOS One, 2009

Background: Age-related macular degeneration (AMD), a chronic neurodegenerative and neovascular r... more Background: Age-related macular degeneration (AMD), a chronic neurodegenerative and neovascular retinal disease, is the leading cause of blindness in elderly people of western European origin. While structural and functional alterations in mitochondria (mt) and their metabolites have been implicated in the pathogenesis of chronic neurodegenerative and vascular diseases, the relationship of inherited variants in the mitochondrial genome and mt haplogroup subtypes with advanced AMD has not been reported in large prospective cohorts.

Inorganic Chemistry, 2006

Even though open-framework solids have been made in a variety of compositions such as silicates, ... more Even though open-framework solids have been made in a variety of compositions such as silicates, phosphates, germanates, borates, and phosphites, few are known that are based on trigonal-pyramidal sulfite anions. We report here the first synthetic and structural studies of metal−organic framework materials in the zinc sulfite composition. It is demonstrated here that Zn 2+ and SO 3 2can form various neutral inorganic subunits that can be 0-D clusters, 1-D chains, or 2-D sheets. These inorganic subunits of different dimensionality can subsequently be connected into extended frameworks of higher dimensionality through bifunctional ligands. In (ZnSO 3 ) 2 en, infinite corrugated ZnSO 3 layers are pillared by ethylenediamine (en) molecules into a 3-D network that can be classified as a (3,4)connected net based on tetrahedral Zn nodes and trigonal-pyramidal S nodes. In (ZnSO 3 )pip, infinite ZnSO 3 chains are cross-linked with piperazine molecules into a 3-D framework that can be classified as 4-connected net based on tetrahedral Zn nodes only. In (ZnSO 3 ) 2 (TMDPy) 2 , (ZnSO 3 ) 2 dimers are doubly bridged by trimethylenedipyridine molecules into an infinite chain with a string of circles. Each circle along the chain is interlocked with another circle from a chain in the perpendicular direction, creating a 2-D pattern with an infinite-square array of catenane-like units.

Journal of Experimental Medicine, 1988

Hybridomas were obtained from 1-or 2-mo-old viable motheaten mice by fusion of splenocytes with t... more Hybridomas were obtained from 1-or 2-mo-old viable motheaten mice by fusion of splenocytes with the Sp2/0 cell line in accordance with a previously described technique

VIABLE MOTHEATEN ANTIBODIES (7) . Hybridomas secreting autoantibodies were cloned under stringent... more VIABLE MOTHEATEN ANTIBODIES (7) . Hybridomas secreting autoantibodies were cloned under stringent limiting dilution conditions (0.5 cell/well) .

... ETM+ data: Possibilities and limitations Alice Wang-Cheng Heng, Soo Chin Liew and Chew Wai Ch... more ... ETM+ data: Possibilities and limitations Alice Wang-Cheng Heng, Soo Chin Liew and Chew Wai Chang Centre for Remote Imaging, Sensing and Processing The National University of Singapore 10 Kent Ridge Cresent Singapore 119260 ...

PLOS One, 2009

Background: Age-related macular degeneration (AMD), a chronic neurodegenerative and neovascular r... more Background: Age-related macular degeneration (AMD), a chronic neurodegenerative and neovascular retinal disease, is the leading cause of blindness in elderly people of western European origin. While structural and functional alterations in mitochondria (mt) and their metabolites have been implicated in the pathogenesis of chronic neurodegenerative and vascular diseases, the relationship of inherited variants in the mitochondrial genome and mt haplogroup subtypes with advanced AMD has not been reported in large prospective cohorts.

Inorganic Chemistry, 2006

Even though open-framework solids have been made in a variety of compositions such as silicates, ... more Even though open-framework solids have been made in a variety of compositions such as silicates, phosphates, germanates, borates, and phosphites, few are known that are based on trigonal-pyramidal sulfite anions. We report here the first synthetic and structural studies of metal−organic framework materials in the zinc sulfite composition. It is demonstrated here that Zn 2+ and SO 3 2can form various neutral inorganic subunits that can be 0-D clusters, 1-D chains, or 2-D sheets. These inorganic subunits of different dimensionality can subsequently be connected into extended frameworks of higher dimensionality through bifunctional ligands. In (ZnSO 3 ) 2 en, infinite corrugated ZnSO 3 layers are pillared by ethylenediamine (en) molecules into a 3-D network that can be classified as a (3,4)connected net based on tetrahedral Zn nodes and trigonal-pyramidal S nodes. In (ZnSO 3 )pip, infinite ZnSO 3 chains are cross-linked with piperazine molecules into a 3-D framework that can be classified as 4-connected net based on tetrahedral Zn nodes only. In (ZnSO 3 ) 2 (TMDPy) 2 , (ZnSO 3 ) 2 dimers are doubly bridged by trimethylenedipyridine molecules into an infinite chain with a string of circles. Each circle along the chain is interlocked with another circle from a chain in the perpendicular direction, creating a 2-D pattern with an infinite-square array of catenane-like units.

Journal of Experimental Medicine, 1988

Hybridomas were obtained from 1-or 2-mo-old viable motheaten mice by fusion of splenocytes with t... more Hybridomas were obtained from 1-or 2-mo-old viable motheaten mice by fusion of splenocytes with the Sp2/0 cell line in accordance with a previously described technique

VIABLE MOTHEATEN ANTIBODIES (7) . Hybridomas secreting autoantibodies were cloned under stringent... more VIABLE MOTHEATEN ANTIBODIES (7) . Hybridomas secreting autoantibodies were cloned under stringent limiting dilution conditions (0.5 cell/well) .

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