Eduardo Colon | University of Minnesota - Twin Cities (original) (raw)

Papers by Eduardo Colon

Comprehensive Psychiatry, May 1, 1991

Thirty-one patients with alopecia areata were administered a structured psychiatric interview (th... more Thirty-one patients with alopecia areata were administered a structured psychiatric interview (the Diagnostic Interview Schedule; DIS). Overall, 74% had one or more lifetime psychiatric diagnoses. Particularly noteworthy were the high lifetime prevalence rates of major ...

Psychosomatics, Nov 1, 1990

The study examined medical records of 121 medical-surgical illpatil'llts diagllOsl'd with adjustm... more The study examined medical records of 121 medical-surgical illpatil'llts diagllOsl'd with adjustmellt disorder hy psychiatric cOl1Sultallts in a ullil'ersity hospital. Medical illlless was the primary stressor. e\'(/king the maladaptil'e reaction in H3 (6R.6lJc) cases. These patiellts were largelyji-ee ofpreceding psychiatric prohlems. sufferillg protracred hospitali:atiollsfor adrallced illnesses. particularly malignancy and diahetes: ill cOlltrast.the 3H (3/Ao/c) patients whose adjustmellt disorder was precipitated hy a stressor Olher thall medical illlless had estahlished psychiatric histories and recurrellt prohlems with relatiollships orfillances. The data suggest that in the medically ill. idelltifyillg the primary stressor producing all adjustmellt disorder is more instrucri"e than!()cusing UpOIl "predominant" symptomatology and "suhtypes." M aligned in past years as a "wastebasket" by some investigators. ' the diagnostic category of adjustment disorders has received surprisingly little systematic investigation. In 1982 Andreasen and Hoenk~found the category to have "at least descriptive and face validity" among adults (but only "panially" so among adolescents). Despite the paucity of formal studies of the category. clinicians have long recognized its utility. It has traditionally referred to short-term disturbances of non psychotic proportions that are provoked by an explicit stressor or stressors.' The

PubMed, Dec 1, 1989

Recurrent self-choking without suicidal intent has received limited attention in the literature; ... more Recurrent self-choking without suicidal intent has received limited attention in the literature; most reports have focused on the sexual nature of the behavior. The authors describe five psychiatric inpatients who engaged in repeated non-erotic self-choking. Similarities in clinical features of the cases include a history of substance abuse (including abuse of volatile substances), aggressive behaviors, a chronic history of psychotic symptoms leading to repeated long-term hospitalizations, and a sense of relief or pleasure, but no overt sexual stimulation, caused by self-choking. The possible role of limbic system dysfunction in this behavior is considered.

Psychosomatics, 1993

To examine the role of psychiatric diagnosis in the surgical outcome of pancreas transplantation,... more To examine the role of psychiatric diagnosis in the surgical outcome of pancreas transplantation, we studied candidates with type I diabetes mellitus. Eighty of 140 candidates underwent transplantation. Survival analysis found the extent of human leukocyte antigen-DR (HLA-DR) matching, two diagnoses, and patients' perceived support from first-degree relatives to be related to duration of full-graft function. Lifetime diagnoses of tobacco use disorder (P = 0.029) and alcohol abuse/dependence (P = 0.006) were associated with less favorable outcomes; perceived support was associated with positive outcomes (P = 0.048). Subsequent analysis suggested that the four variables independently and directly affect outcome.

Archives of General Psychiatry, 1988

To examine the prevalence of psychiatric disorders in patients with long-standing type I diabetes... more To examine the prevalence of psychiatric disorders in patients with long-standing type I diabetes mellitus, we assessed a series of candidates for pancreas transplantation. Using the Diagnostic Interview Schedule, six-month and lifetime prevalences of psychiatric disorders were established for the candidates and their potential donors (first-degree relatives). Excluding tobacco use disorder and psychosexual dysfunction, 38 diabetic subjects (51%) received one or more psychiatric diagnoses. The lifetime prevalence of major depression was comparable for female (11 of 48 [22.9%]) and male (seven of 27 [25.9%]) diabetics; both rates were significantly higher than rates in first-degree relatives and the general population. Among female diabetics, the six-month and lifetime prevalences of simple phobia were increased vs donors and the general population; among male diabetics, the lifetime prevalence of antisocial personality disorder was greater than that in the general population. None of these disorders was found to be related to the duration of diabetes or the presence of various complications. The data suggest that increased rates of psychiatric disorder in type I diabetics have both gender-independent and gender-related components.

Seminars in Clinical Neuropsychiatry

Acta Psychiatrica Scandinavica, 1988

3,258 randomly selected adult household residents of Edmonton were interviewed by trained lay int... more 3,258 randomly selected adult household residents of Edmonton were interviewed by trained lay interviewers using the Diagnostic Interview Schedule (DIS). Lifetime prevalence for 16 DIS/DSM III diagnoses are given. Overall 33.8% of the population had one or more diagnoses and, excluding substance use disorders, one fifth of the population had a diagnosis. The most common lifetime diagnosis was alcohol abuse/dependence, followed by phobia and major depressive episode. Men were more likely to have had substance use disorders and antisocial personality disorder and women more likely to have had major depressive episode, dysthymia, agoraphobia and simple phobia. Those who were married had generally lower lifetime prevalences. Those over age 65 had the lowest prevalence of any age groups.

International Clinical Psychopharmacology, 2017

The aim of this study was to determine whether the incidence of pneumonia in patients taking cloz... more The aim of this study was to determine whether the incidence of pneumonia in patients taking clozapine was more frequent compared with those taking risperidone or no atypical antipsychotics at all before admission to a tertiary care medical center. This was a retrospective, casematched study of 465 general medicine patients over a 25 month period from 1 July 2010 to 31 July 2012. Detailed electronic medical records were analyzed to explore the association between the use of two atypical antipsychotics and incidence of pneumonia. Of the 155 patients in the clozapine group, 54 (34.8%) had documented pneumonia compared with 22 (14.2%) in the risperidone group and 18 (11.6%) in the general population group. Clozapine, when compared with the untreated general population, was associated with an increased risk of pneumonia (odds ratio = 4.07; 95% confidence interval = 2.25-7.36). There was, however, no significant increase in the risk of pneumonia associated with the use of risperidone (odds ratio = 1.26; 95% confidence interval = 0.65-2.45). Clozapine use is associated with increased risk of pneumonia that may be related to immunologic factors or side effects of sedation and drooling that make aspiration more likely, although causative mechanisms require further investigation. These findings suggest that providers should use added caution in choosing candidates for clozapine therapy. Int Clin Psychopharmacol 32:155-160

Psychosomatic Medicine, 2016

I would like to extend my sincere thanks to our Associate Editors and Editorial Board members as ... more I would like to extend my sincere thanks to our Associate Editors and Editorial Board members as well as other colleagues who have taken time out of their busy schedules to review manuscripts for Psychosomatic Medicine: Journal of Biobehavioral Medicine. I am especially appreciative of those who have done multiple reviews. The quality of the journal is enhanced greatly by their efforts.

Current Psychiatry Reports, 2006

Panic disorder is a common illness with significant impact on function and, at times, disabling c... more Panic disorder is a common illness with significant impact on function and, at times, disabling consequences. Advances over recent years have yielded potential pathophysiologic mechanisms, including neurotransmitter systems and neural substrates. This article provides an overview of various models and hypotheses regarding the etiology of panic disorder. Because its symptoms overlap with the symptoms of various medical disorders, this discussion reviews the comorbidity of panic disorder with medical conditions, especially cardiac and respiratory disorders.

Annals of allergy, 1993

The study was conducted to evaluate the effects of having allergic reactions (ie, being in allerg... more The study was conducted to evaluate the effects of having allergic reactions (ie, being in allergy seasons without taking medications) on: (1) speed of cognitive processing, (2) psychomotor speed, (3) ability to sustain attention, (4) verbal learning and memory, and (5) mood. Subjects (ten atopic, eight control) were given a neuropsychologic test and mood rating battery in an A-B-A design ie, in, out of, and in allergy seasons. Only atopic subjects exhibited declines in verbal learning, slower decision-making and psychomotor speed on both simple and choice reaction time tests, and lower positive affect during their allergy seasons in comparison to out of allergy seasons. Atopic subjects did not demonstrate declines in ability to sustain attention. Biochemical mechanisms may cause these changes.

Psychosomatics, 1987

ABSTRACT

Transplantation Reviews, 1991

Journal of Clinical Psychology in Medical Settings - J CLIN PSYCHOL MED SETTINGS, 2003

As some psychologists advocate for prescription privileges, the need for closer analysis of the d... more As some psychologists advocate for prescription privileges, the need for closer analysis of the differences between psychologists and psychiatrists grows. Our data reveal key gaps in psychologists' training and significant limitations in their knowledge pertaining to prescribing relative to psychiatrists. Attitudes toward prescribing and estimates of psychologists' competence in prescribing are presented. The authors believe that psychologists' deficits in training and pertinent knowledge constitute major hurdles to competent prescribing. Caution is warranted about expanding psychologists' scope of practice to include prescribing.

Psychosomatics, 1988

A series of465 consecutive psychiatric consultations to medical-surgical services was examined to... more A series of465 consecutive psychiatric consultations to medical-surgical services was examined to compare consultations designated as emergencies with those requested on a routine basis. Twenty-three percent ofthe consultation requests were designated as emergencies. and psychotic thinking and suicidality were noted more frequently in this group. Emergencies. however. were invoked less frequently in patients 60 years ofage or older. The consultant's approach to emergency consultations demonstrates a more active role. with more recommendations for initiation ofpsychotropic drugs. more follow-up visits. greater numbers ofrecommendations for disposition. and greater numbers ofcontacts with outside sources ofinformation effected. Notably. concordance with diagnostic and psychotropic drug recommendations and representation ofpsychiatric diagnosis in discharge summaries did not differ significantly between the two groups. The results underscore the usefulness ofclosely monitoring consultation outcomes and the need to explore and implement interventions that will enhance consultee responses in situations requiring acute psychiatric interventions.

Psychosomatics, 1991

Routine psychiatric evaluations of 100 adult patients undergoing allogeneic bone marrow transplan... more Routine psychiatric evaluations of 100 adult patients undergoing allogeneic bone marrow transplantation for acute leukemia were reviewed to examine the possible relationship ofpsychiatric and psychosocialfactors to duration ofsurvivalfollowing the procedure. Three variables were found to independently affect outcome: illness status (first remission vs. other status), presence ofdepressed mood, and the extent ofperceived social support. Patients transpl(Jnted while in their first remission had significantly improved survival; patients with depressed mood, regardless ofspecific psychiatric diagnosis, had poorer outcomes; and patients with a high level ofperceived social support had improved survival. The possible mechanisms by which these variables affect outcome are discussed. B one marrow transplantation has emerged as a treatment alternative and. in some instances. the treatment of choice for a variety of hematologic disorders. 1.2 A recent report from the International Bone Marrow Transplant Registry described a 20-fold increase in the use of this procedure from 1977 to 1987. 3 Of the 10.887 transplants included in the report. 75% were for the treatment of leukemia. The transplantation procedure initially requires eradication of the

Psychosomatics, 1990

Pharmacology Biochemistry and Behavior, 1990

smoked cocaine-base use, there have been relatively few parametric studies in this area. The majo... more smoked cocaine-base use, there have been relatively few parametric studies in this area. The major reason for the limited number of studies is the lack of a simple procedure for the administration of precise doses of smoked cocaine-base to human volunteers. This paper describes a new method that allows for the delivery of precise doses of smoked cocaine-base. A complete description of the method and the precision of the administration procedure are presented. Furthermore, a study is described which was undertaken to determine: 1) the reproducibility of peak blood cocaine levels when the same dose of cocaine was given on two separate occasions; and 2) the dose-related effects on smoking topography, biochemical, physiological and subjective measures. Subjects (N = 5) were administered three doses of cocaine-base (10, 20 and 40 mg). Four subjects were given repeated doses of cocaine-base. Subjects were blind to the dose and in most cases randomly assigned to different doses. The results showed: 1) a significant correlation of peak whole blood cocaine concentrations among similar doses within subjects (r = .99); 2) no significant effects of dose on smoking topography; and 3) significant dose effects for whole blood cocaine concentrations, heart rate and systolic blood pressure.