Muthukumar Govindaraj | SRM Universtiy (original) (raw)

Papers by Muthukumar Govindaraj

ACS applied nano materials, Jan 9, 2023

Please cite this article as: A. Akhundi, A. Habibi-Yangjeh, Graphitic carbon nitride nanosheets d... more Please cite this article as: A. Akhundi, A. Habibi-Yangjeh, Graphitic carbon nitride nanosheets decorated with CuCr 2 O 4 nanoparticles: Novel photocatalysts with high performances in visible light degradation of water pollutants,

ChemNanoMat

In the scientific community, developing a non‐enzymatic detection tool for highly reliable and se... more In the scientific community, developing a non‐enzymatic detection tool for highly reliable and sensitive identification of the targeted biomolecules is challenging. Sulfamethazine (SMZ), a bacterial inhibitor frequently used as an antibacterial medicine, can cause antimicrobial resistance (AMR) in humans if taken in excess. Hence, there is a need for a reliable and rapid sensor that can detect SMZ in food and aquatic environments. The goal of this study aims to develop a novel, inexpensive 2D/2D hexagonal boron nitride/protonated carbon nitride (h‐BN/PCN) nanohybrid that can function as an electrocatalyst for SMZ sensing. The as‐synthesized material‘s crystalline, structural, chemical, and self‐assembly properties were thoroughly characterized by XRD, HR‐TEM, XPS, HR‐SEM, FT‐IR, and ZETA potential and electrochemical sensing capacity of the suggested electrodes was optimized using CV, EIS, DPV, and i‐t curve techniques. The above nanohybrid of h‐BN/PCN‐modified GCE exhibits improved...

International Journal of Biological Macromolecules

This review discusses the most current developments and future perspectives in enzymatic and non-... more This review discusses the most current developments and future perspectives in enzymatic and non-enzymatic glucose sensors, which have notably evolved over the preceding quadrennial period. Furthermore, a thorough exploration encompassed the sensor's intricate fabrication processes, the diverse range of materials employed, the underlying principles of detection, and an in-depth assessment of the sensors' efficacy in detecting glucose levels within essential bodily fluids such as human blood serums, urine, saliva, and interstitial fluids. It is worth noting that the accurate quantification of glucose concentrations within human blood has been effectively achieved by utilizing classical enzymatic sensors harmoniously integrated with optical and electrochemical transduction mechanisms. Monitoring glucose levels in various mediums has attracted exceptional attention from industrial to academic researchers for diabetes management, food quality control, clinical medicine, and bioprocess inspection. There has been an enormous demand for the creation of novel glucose sensors over the past ten years. Research has primarily concentrated on succeeding biocompatible and enhanced sensing abilities related to the present technologies, offering innovative avenues for more effective glucose sensors. Recent developments in wearable optical and electrochemical sensors with low cost, high stability, point-of-care testing, and online tracking of glucose concentration levels in biological fluids can aid in managing and controlling diabetes globally. New nanomaterials and biomolecules that can be used in electrochemical sensor systems to identify glucose concentration levels are developed thanks to advances in nanoscience and nanotechnology. Both enzymatic and non-enzymatic glucose electrochemical sensors have garnered much interest recently and have made significant strides in detecting glucose levels. In this review, we summarise several categories of non-enzymatic glucose sensor materials, including composites, non-precious transition metals and their metal oxides, hydroxides, precious metals and their alloys, carbon-based materials, conducting polymers, metal-organic framework (MOF)-based electrocatalysts, and wearable device-based glucose sensors deeply.

Analytical Methods

A SrO/h-BN composite was successfully fabricated for the first time, realizing excellent 5-fluoro... more A SrO/h-BN composite was successfully fabricated for the first time, realizing excellent 5-fluorouracil (an anticancer drug) sensing with extremely high sensitivity, low detection limit, wide detection range, good selectivity and stability.

Analytical Methods, 2023

In this work, the crystal plane of strontium oxide (SrO) nanorods was integrated into hexagonal-b... more In this work, the crystal plane of strontium oxide (SrO) nanorods was integrated into hexagonal-boron nitride (h-BN) nanosheets to form 1D-2D (SrO/h-BN) composite were utilized for the electrochemical detection of the chemotherapeutic drug 5-fluorouracil (5-Fu). 5-Fu is a clinically proven and the third most frequently applied chemotherapeutic drug for treating solid tumours, such as colorectal, stomach, cutaneous and breast malignancies. Its overdoses lead to toxic metabolite accumulation that has serious adverse consequences on humans, including neurotoxicity, death and the induction of morbidity. Therefore, to improve the chemotherapy and predict the potential adverse effects of 5-Fu residues in the human body, susceptible and quick analytical methods for detecting 5-Fu in human body fluids (blood serum/plasma and urine) are needed. The effective interaction of the synthesized SrO/h-BN composite shows increased efficiency for the electrochemical detection of 5-Fu with good selectivity. Notably, a simple sonochemical method achieved a synergistic interaction between the (100) plane of SrO and the (002) plane of h-BN. Various analytical and spectroscopic techniques were used to characterize the SrO/h-BN nanocomposite, which provided useful insights into the composition and properties of the composite material. The crystalline, structural and chemical characteristics of the as-synthesized material were characterized by XRD, Raman spectroscopy, HR-TEM, XPS and HR-SEM. Furthermore, the proposed electrode's electrochemical sensing capability was analysed using CV, EIS, DPV and it curve methods. Numerous active sites created on a modified electrode enhanced the mass transport and electron transfer rate, thereby increasing the electrochemical activity towards the 5-Fu detection. Consequently, under optimized conditions, the SrO/h-BN/GCE exhibited remarkable selectivity, durability, low detection limit (0.003 mM) and wide linear range (0.02-56 mM) for 5-Fu. Finally, the successful application of this sensor for 5-Fu detection in biological samples was successfully tested with high recovery percentages.

ACS Applied Nano Materials, 2023

Sulfamethazine (SMZ) is one of the most frequently utilized sulfonamides, and it is regularly fou... more Sulfamethazine (SMZ) is one of the most frequently utilized sulfonamides, and it is regularly found in animal-derived foods, posing a health risk. Hence, developing a quick, easy, selective, and sensitive analytical method for on-site detection of SMZ is essential for improving food safety. Recently, transition-metal oxides have attracted great interest as promising sensors for detecting sulfamethazine due to their superior redox behavior, electrochemical activity, and electroactive sites. However, they tremendously suffer from poor electrical conductivity and electrochemical stability, which limits their commercial reality. Herein, a highly selective sensor consisting of two-dimensional (2D) graphitic carbon nitride nanosheet (g-C 3 N 4) networks anchored to strontium tungstate nanospheres (denoted as SrWO 4 /g-C 3 N 4) is developed for nonenzymatic sulfamethazine detection. When employed as the sensing platform, the SrWO 4 / g-C 3 N 4 hybrid shows enhanced sensing performance with a fast response time, high sensitivity, low detection limit of 0.0059 μM, wide detection ranges from 0.2 to 600 μM, and prolonged cycle life of over 30 days. The sensor performs well in sulfamethazine in real sample analysis, reflecting its practical applicability. Such a performance may be attributed to the numerous electroactive sites, confined electronic structures, and high synergistic interaction between active SrWO 4 species and the g-C 3 N 4 matrix. This work demonstrates an innovative protocol for developing SrWO 4 /g-C 3 N 4-based sensing platforms with nanoscale architectures and high interface configurations.

International Journal of Biological Macromolecules, 2023

This review discusses the most current developments and future perspectives in enzymatic and non-... more This review discusses the most current developments and future perspectives in enzymatic and non-enzymatic glucose sensors, which have notably evolved over the preceding quadrennial period. Furthermore, a thorough exploration encompassed the sensor's intricate fabrication processes, the diverse range of materials employed, the underlying principles of detection, and an in-depth assessment of the sensors' efficacy in detecting glucose levels within essential bodily fluids such as human blood serums, urine, saliva, and interstitial fluids. It is worth noting that the accurate quantification of glucose concentrations within human blood has been effectively achieved by utilizing classical enzymatic sensors harmoniously integrated with optical and electrochemical transduction mechanisms. Monitoring glucose levels in various mediums has attracted exceptional attention from industrial to academic researchers for diabetes management, food quality control, clinical medicine, and bioprocess inspection. There has been an enormous demand for the creation of novel glucose sensors over the past ten years. Research has primarily concentrated on succeeding biocompatible and enhanced sensing abilities related to the present technologies, offering innovative avenues for more effective glucose sensors. Recent developments in wearable optical and electrochemical sensors with low cost, high stability, point-of-care testing, and online tracking of glucose concentration levels in biological fluids can aid in managing and controlling diabetes globally. New nanomaterials and biomolecules that can be used in electrochemical sensor systems to identify glucose concentration levels are developed thanks to advances in nanoscience and nanotechnology. Both enzymatic and non-enzymatic glucose electrochemical sensors have garnered much interest recently and have made significant strides in detecting glucose levels. In this review, we summarise several categories of non-enzymatic glucose sensor materials, including composites, non-precious transition metals and their metal oxides, hydroxides, precious metals and their alloys, carbon-based materials, conducting polymers, metal-organic framework (MOF)-based electrocatalysts, and wearable device-based glucose sensors deeply.

ChemNanoMat, 2023

In the scientific community, developing a non-enzymatic detection tool for highly reliable and se... more In the scientific community, developing a non-enzymatic detection tool for highly reliable and sensitive identification of the targeted biomolecules is challenging. Sulfamethazine (SMZ), a bacterial inhibitor frequently used as an antibacterial medicine, can cause antimicrobial resistance (AMR) in humans if taken in excess. Hence, there is a need for a reliable and rapid sensor that can detect SMZ in food and aquatic environments. The goal of this study aims to develop a novel, inexpensive 2D/ 2D hexagonal boron nitride/protonated carbon nitride (h-BN/ PCN) nanohybrid that can function as an electrocatalyst for SMZ sensing. The as-synthesized material's crystalline, structural, chemical, and self-assembly properties were thoroughly characterized by XRD, HR-TEM, XPS, HR-SEM, FT-IR, and ZETA potential and electrochemical sensing capacity of the suggested electrodes was optimized using CV, EIS, DPV, and it curve techniques. The above nanohybrid of h-BN/PCN-modified GCE exhibits improved non-enzymatic sulfamethazine sensing behaviour, with a response time of less than 1.83 s, a sensitivity of 1.80 μA μM À 1 cm À 2 , a detection limit of 0.00298 μM, and a range of 10 nM to 200 μM. The electrochemical analysis proves that the conductivity of h-BN has significantly improved after assembling PCN due to the large surface area with active surface sites and the synergistic effect. Notably, our constructed sensor demonstrated outstanding selectivity over a range of probable interferents, and electrochemical studies indicate that the suggested sensor has improved functional durability, rapid response, impartial repeatability, and reproducibility. Furthermore, the feasibility of an h-BN/PCN-modified sensor to detect the presence of SMZ in food samples consumed by humans has been successfully tested with high recovery percentages.

RSC Advances

A PTh/h-BN composite was successfully fabricated for the first time, realizing excellent 5-fluoro... more A PTh/h-BN composite was successfully fabricated for the first time, realizing excellent 5-fluorouracil sensing in the real sample with high sensitivity and selectivity, lowest LOD, wide linear range, and stability.

RSC Advances

A PTh/h-BN composite was successfully fabricated for the first time, realizing excellent 5-fluoro... more A PTh/h-BN composite was successfully fabricated for the first time, realizing excellent 5-fluorouracil sensing in the real sample with high sensitivity and selectivity, lowest LOD, wide linear range, and stability.

nt J Nano Corr Sci and Engg, 2016

Corrosion resistance of Super Elastic Nickel-Titanium alloy in artificial saliva, in theabsence a... more Corrosion resistance of Super Elastic Nickel-Titanium alloy in artificial saliva, in theabsence and presence of a tablet namely, Almox 250mg has been evaluated by AC ImpedanceSpectra. It is observed that when 50 ppm of Almox is added to artificial saliva, charge transferresistance of Super Elastic Nickel-Titanium increases. Similar observation is made in presence of200 ppm of Almox also. Hence it is concluded that people having orthodontic wires made of Titanium, can take the Tablet Almox 250mg without any hesitation,nce corrosion resistance of Super Elastic Nickel-Titanium increases.

RSC Advances, 2023

It is difficult for the scientific community to develop a nonenzymatic sensing platform for extre... more It is difficult for the scientific community to develop a nonenzymatic sensing platform for extremely sensitive and selective detection of specific biomolecules, antibiotics, food adulterants, heavy metals, etc. One of the most significant chemotherapy drugs, 5-fluorouracil (5-Fu), which is used to treat solid malignancies, has a fluorine atom in the fifth position of the uracil molecule. Recognizing the secure and effective dosing of drugs for chemotherapy continues to be a critical concern in cancer disease management. The maintenance of the optimal 5-Fu concentration is dependent on the presence of 5-Fu in biofluids. Herein we reported a conducting polymer encapsulated 2D material, PTh/h-BN for the efficient electrochemical detection of anticancer drug 5-Fu. Furthermore, the synthesized PTh/h-BN nanocomposite was confirmed by the High-Resolution Transmission Electron Microscope (HR-TEM), High-Resolution Scanning Electron Microscope (HR-SEM), X-ray diffraction (XRD), and Fourier-Transform Infrared Spectroscopy (FT-IR). The electrical resistance of PTh/h-BN modified GCE and its sensing performance towards 5-Fu were tested using Electrochemical Impedance Spectroscopy (EIS) and Cyclic Voltammetry (CV) studies respectively. The analytical performance of our proposed catalyst was tested using Differential Pulse Voltammetry (DPV), and the amperometry (i-t curve) method. From the results, our proposed PTh/h-BN nanocomposite-modified GCE shows enhanced sensing performance due to higher redox peak currents, large active surface area, and high electrical conductivity. Moreover, the nanohybrid shows enhanced sensing performances with quick response time, wide linear range, the lowest limit of detection, high sensitivity, and high selectivity in the presence of various interferents. Finally, the practical applicability of the proposed sensor was tested with real-world samples with very good recovery percentages.

ACS applied nano materials, Jan 9, 2023

Please cite this article as: A. Akhundi, A. Habibi-Yangjeh, Graphitic carbon nitride nanosheets d... more Please cite this article as: A. Akhundi, A. Habibi-Yangjeh, Graphitic carbon nitride nanosheets decorated with CuCr 2 O 4 nanoparticles: Novel photocatalysts with high performances in visible light degradation of water pollutants,

ChemNanoMat

In the scientific community, developing a non‐enzymatic detection tool for highly reliable and se... more In the scientific community, developing a non‐enzymatic detection tool for highly reliable and sensitive identification of the targeted biomolecules is challenging. Sulfamethazine (SMZ), a bacterial inhibitor frequently used as an antibacterial medicine, can cause antimicrobial resistance (AMR) in humans if taken in excess. Hence, there is a need for a reliable and rapid sensor that can detect SMZ in food and aquatic environments. The goal of this study aims to develop a novel, inexpensive 2D/2D hexagonal boron nitride/protonated carbon nitride (h‐BN/PCN) nanohybrid that can function as an electrocatalyst for SMZ sensing. The as‐synthesized material‘s crystalline, structural, chemical, and self‐assembly properties were thoroughly characterized by XRD, HR‐TEM, XPS, HR‐SEM, FT‐IR, and ZETA potential and electrochemical sensing capacity of the suggested electrodes was optimized using CV, EIS, DPV, and i‐t curve techniques. The above nanohybrid of h‐BN/PCN‐modified GCE exhibits improved...

International Journal of Biological Macromolecules

This review discusses the most current developments and future perspectives in enzymatic and non-... more This review discusses the most current developments and future perspectives in enzymatic and non-enzymatic glucose sensors, which have notably evolved over the preceding quadrennial period. Furthermore, a thorough exploration encompassed the sensor's intricate fabrication processes, the diverse range of materials employed, the underlying principles of detection, and an in-depth assessment of the sensors' efficacy in detecting glucose levels within essential bodily fluids such as human blood serums, urine, saliva, and interstitial fluids. It is worth noting that the accurate quantification of glucose concentrations within human blood has been effectively achieved by utilizing classical enzymatic sensors harmoniously integrated with optical and electrochemical transduction mechanisms. Monitoring glucose levels in various mediums has attracted exceptional attention from industrial to academic researchers for diabetes management, food quality control, clinical medicine, and bioprocess inspection. There has been an enormous demand for the creation of novel glucose sensors over the past ten years. Research has primarily concentrated on succeeding biocompatible and enhanced sensing abilities related to the present technologies, offering innovative avenues for more effective glucose sensors. Recent developments in wearable optical and electrochemical sensors with low cost, high stability, point-of-care testing, and online tracking of glucose concentration levels in biological fluids can aid in managing and controlling diabetes globally. New nanomaterials and biomolecules that can be used in electrochemical sensor systems to identify glucose concentration levels are developed thanks to advances in nanoscience and nanotechnology. Both enzymatic and non-enzymatic glucose electrochemical sensors have garnered much interest recently and have made significant strides in detecting glucose levels. In this review, we summarise several categories of non-enzymatic glucose sensor materials, including composites, non-precious transition metals and their metal oxides, hydroxides, precious metals and their alloys, carbon-based materials, conducting polymers, metal-organic framework (MOF)-based electrocatalysts, and wearable device-based glucose sensors deeply.

Analytical Methods

A SrO/h-BN composite was successfully fabricated for the first time, realizing excellent 5-fluoro... more A SrO/h-BN composite was successfully fabricated for the first time, realizing excellent 5-fluorouracil (an anticancer drug) sensing with extremely high sensitivity, low detection limit, wide detection range, good selectivity and stability.

Analytical Methods, 2023

In this work, the crystal plane of strontium oxide (SrO) nanorods was integrated into hexagonal-b... more In this work, the crystal plane of strontium oxide (SrO) nanorods was integrated into hexagonal-boron nitride (h-BN) nanosheets to form 1D-2D (SrO/h-BN) composite were utilized for the electrochemical detection of the chemotherapeutic drug 5-fluorouracil (5-Fu). 5-Fu is a clinically proven and the third most frequently applied chemotherapeutic drug for treating solid tumours, such as colorectal, stomach, cutaneous and breast malignancies. Its overdoses lead to toxic metabolite accumulation that has serious adverse consequences on humans, including neurotoxicity, death and the induction of morbidity. Therefore, to improve the chemotherapy and predict the potential adverse effects of 5-Fu residues in the human body, susceptible and quick analytical methods for detecting 5-Fu in human body fluids (blood serum/plasma and urine) are needed. The effective interaction of the synthesized SrO/h-BN composite shows increased efficiency for the electrochemical detection of 5-Fu with good selectivity. Notably, a simple sonochemical method achieved a synergistic interaction between the (100) plane of SrO and the (002) plane of h-BN. Various analytical and spectroscopic techniques were used to characterize the SrO/h-BN nanocomposite, which provided useful insights into the composition and properties of the composite material. The crystalline, structural and chemical characteristics of the as-synthesized material were characterized by XRD, Raman spectroscopy, HR-TEM, XPS and HR-SEM. Furthermore, the proposed electrode's electrochemical sensing capability was analysed using CV, EIS, DPV and it curve methods. Numerous active sites created on a modified electrode enhanced the mass transport and electron transfer rate, thereby increasing the electrochemical activity towards the 5-Fu detection. Consequently, under optimized conditions, the SrO/h-BN/GCE exhibited remarkable selectivity, durability, low detection limit (0.003 mM) and wide linear range (0.02-56 mM) for 5-Fu. Finally, the successful application of this sensor for 5-Fu detection in biological samples was successfully tested with high recovery percentages.

ACS Applied Nano Materials, 2023

Sulfamethazine (SMZ) is one of the most frequently utilized sulfonamides, and it is regularly fou... more Sulfamethazine (SMZ) is one of the most frequently utilized sulfonamides, and it is regularly found in animal-derived foods, posing a health risk. Hence, developing a quick, easy, selective, and sensitive analytical method for on-site detection of SMZ is essential for improving food safety. Recently, transition-metal oxides have attracted great interest as promising sensors for detecting sulfamethazine due to their superior redox behavior, electrochemical activity, and electroactive sites. However, they tremendously suffer from poor electrical conductivity and electrochemical stability, which limits their commercial reality. Herein, a highly selective sensor consisting of two-dimensional (2D) graphitic carbon nitride nanosheet (g-C 3 N 4) networks anchored to strontium tungstate nanospheres (denoted as SrWO 4 /g-C 3 N 4) is developed for nonenzymatic sulfamethazine detection. When employed as the sensing platform, the SrWO 4 / g-C 3 N 4 hybrid shows enhanced sensing performance with a fast response time, high sensitivity, low detection limit of 0.0059 μM, wide detection ranges from 0.2 to 600 μM, and prolonged cycle life of over 30 days. The sensor performs well in sulfamethazine in real sample analysis, reflecting its practical applicability. Such a performance may be attributed to the numerous electroactive sites, confined electronic structures, and high synergistic interaction between active SrWO 4 species and the g-C 3 N 4 matrix. This work demonstrates an innovative protocol for developing SrWO 4 /g-C 3 N 4-based sensing platforms with nanoscale architectures and high interface configurations.

International Journal of Biological Macromolecules, 2023

This review discusses the most current developments and future perspectives in enzymatic and non-... more This review discusses the most current developments and future perspectives in enzymatic and non-enzymatic glucose sensors, which have notably evolved over the preceding quadrennial period. Furthermore, a thorough exploration encompassed the sensor's intricate fabrication processes, the diverse range of materials employed, the underlying principles of detection, and an in-depth assessment of the sensors' efficacy in detecting glucose levels within essential bodily fluids such as human blood serums, urine, saliva, and interstitial fluids. It is worth noting that the accurate quantification of glucose concentrations within human blood has been effectively achieved by utilizing classical enzymatic sensors harmoniously integrated with optical and electrochemical transduction mechanisms. Monitoring glucose levels in various mediums has attracted exceptional attention from industrial to academic researchers for diabetes management, food quality control, clinical medicine, and bioprocess inspection. There has been an enormous demand for the creation of novel glucose sensors over the past ten years. Research has primarily concentrated on succeeding biocompatible and enhanced sensing abilities related to the present technologies, offering innovative avenues for more effective glucose sensors. Recent developments in wearable optical and electrochemical sensors with low cost, high stability, point-of-care testing, and online tracking of glucose concentration levels in biological fluids can aid in managing and controlling diabetes globally. New nanomaterials and biomolecules that can be used in electrochemical sensor systems to identify glucose concentration levels are developed thanks to advances in nanoscience and nanotechnology. Both enzymatic and non-enzymatic glucose electrochemical sensors have garnered much interest recently and have made significant strides in detecting glucose levels. In this review, we summarise several categories of non-enzymatic glucose sensor materials, including composites, non-precious transition metals and their metal oxides, hydroxides, precious metals and their alloys, carbon-based materials, conducting polymers, metal-organic framework (MOF)-based electrocatalysts, and wearable device-based glucose sensors deeply.

ChemNanoMat, 2023

In the scientific community, developing a non-enzymatic detection tool for highly reliable and se... more In the scientific community, developing a non-enzymatic detection tool for highly reliable and sensitive identification of the targeted biomolecules is challenging. Sulfamethazine (SMZ), a bacterial inhibitor frequently used as an antibacterial medicine, can cause antimicrobial resistance (AMR) in humans if taken in excess. Hence, there is a need for a reliable and rapid sensor that can detect SMZ in food and aquatic environments. The goal of this study aims to develop a novel, inexpensive 2D/ 2D hexagonal boron nitride/protonated carbon nitride (h-BN/ PCN) nanohybrid that can function as an electrocatalyst for SMZ sensing. The as-synthesized material's crystalline, structural, chemical, and self-assembly properties were thoroughly characterized by XRD, HR-TEM, XPS, HR-SEM, FT-IR, and ZETA potential and electrochemical sensing capacity of the suggested electrodes was optimized using CV, EIS, DPV, and it curve techniques. The above nanohybrid of h-BN/PCN-modified GCE exhibits improved non-enzymatic sulfamethazine sensing behaviour, with a response time of less than 1.83 s, a sensitivity of 1.80 μA μM À 1 cm À 2 , a detection limit of 0.00298 μM, and a range of 10 nM to 200 μM. The electrochemical analysis proves that the conductivity of h-BN has significantly improved after assembling PCN due to the large surface area with active surface sites and the synergistic effect. Notably, our constructed sensor demonstrated outstanding selectivity over a range of probable interferents, and electrochemical studies indicate that the suggested sensor has improved functional durability, rapid response, impartial repeatability, and reproducibility. Furthermore, the feasibility of an h-BN/PCN-modified sensor to detect the presence of SMZ in food samples consumed by humans has been successfully tested with high recovery percentages.

RSC Advances

A PTh/h-BN composite was successfully fabricated for the first time, realizing excellent 5-fluoro... more A PTh/h-BN composite was successfully fabricated for the first time, realizing excellent 5-fluorouracil sensing in the real sample with high sensitivity and selectivity, lowest LOD, wide linear range, and stability.

RSC Advances

A PTh/h-BN composite was successfully fabricated for the first time, realizing excellent 5-fluoro... more A PTh/h-BN composite was successfully fabricated for the first time, realizing excellent 5-fluorouracil sensing in the real sample with high sensitivity and selectivity, lowest LOD, wide linear range, and stability.

nt J Nano Corr Sci and Engg, 2016

Corrosion resistance of Super Elastic Nickel-Titanium alloy in artificial saliva, in theabsence a... more Corrosion resistance of Super Elastic Nickel-Titanium alloy in artificial saliva, in theabsence and presence of a tablet namely, Almox 250mg has been evaluated by AC ImpedanceSpectra. It is observed that when 50 ppm of Almox is added to artificial saliva, charge transferresistance of Super Elastic Nickel-Titanium increases. Similar observation is made in presence of200 ppm of Almox also. Hence it is concluded that people having orthodontic wires made of Titanium, can take the Tablet Almox 250mg without any hesitation,nce corrosion resistance of Super Elastic Nickel-Titanium increases.

RSC Advances, 2023

It is difficult for the scientific community to develop a nonenzymatic sensing platform for extre... more It is difficult for the scientific community to develop a nonenzymatic sensing platform for extremely sensitive and selective detection of specific biomolecules, antibiotics, food adulterants, heavy metals, etc. One of the most significant chemotherapy drugs, 5-fluorouracil (5-Fu), which is used to treat solid malignancies, has a fluorine atom in the fifth position of the uracil molecule. Recognizing the secure and effective dosing of drugs for chemotherapy continues to be a critical concern in cancer disease management. The maintenance of the optimal 5-Fu concentration is dependent on the presence of 5-Fu in biofluids. Herein we reported a conducting polymer encapsulated 2D material, PTh/h-BN for the efficient electrochemical detection of anticancer drug 5-Fu. Furthermore, the synthesized PTh/h-BN nanocomposite was confirmed by the High-Resolution Transmission Electron Microscope (HR-TEM), High-Resolution Scanning Electron Microscope (HR-SEM), X-ray diffraction (XRD), and Fourier-Transform Infrared Spectroscopy (FT-IR). The electrical resistance of PTh/h-BN modified GCE and its sensing performance towards 5-Fu were tested using Electrochemical Impedance Spectroscopy (EIS) and Cyclic Voltammetry (CV) studies respectively. The analytical performance of our proposed catalyst was tested using Differential Pulse Voltammetry (DPV), and the amperometry (i-t curve) method. From the results, our proposed PTh/h-BN nanocomposite-modified GCE shows enhanced sensing performance due to higher redox peak currents, large active surface area, and high electrical conductivity. Moreover, the nanohybrid shows enhanced sensing performances with quick response time, wide linear range, the lowest limit of detection, high sensitivity, and high selectivity in the presence of various interferents. Finally, the practical applicability of the proposed sensor was tested with real-world samples with very good recovery percentages.