Bhupendra Mahanta | Srimanta Sankaradeva University Of Health Sciences (original) (raw)

Papers by Bhupendra Mahanta

Research paper thumbnail of Citation

Anaemia, its determinants and effect of different interventions amongst tea tribe

Research paper thumbnail of KEYWORDSMetabolic Syndrome (MetS), Dietary Risk Factor, Food Frequency Questionnaire (FFQ), Cardiovascular Disease (CVD), Assam

Research paper thumbnail of Quality of Hypertension Management in Type 2 Diabetes in India: A Multisite Prescription Audit

Background and Objective Renin-angiotensin system (RAS) blockers (angiotensin converting enzyme i... more Background and Objective Renin-angiotensin system (RAS) blockers (angiotensin converting enzyme inhibitors ACEI, angiotensin receptor blockers, ARB) are preferred drugs to control hypertension among diabetic patients. To determine frequency of RAS blocker use in hypertensive patients with type 2 diabetes, we performed a multisite study in India. Methods We evaluated physician prescriptions in consecutive patients with type 2 diabetes at 9 sites in India. Details of socio-demographic characteristics, clinical findings and prescription medicines were obtained. Descriptive statistics are reported. Results Hypertension treatment details were available in 8056 of 8699 diabetic patients (4829 men, 3227 women). No hypertension was in 3300 (40.9%), hypertension in 3625 (45.0%), and hypertension with vascular disease in 1131 (14.0%). In diabetics with no hypertension, hypertension, and hypertension with vascular disease, respectively, prescriptions of antihypertensive drugs was: RAS blockers...

Research paper thumbnail of Dietary Diversity and its effect on anaemia prevalence amongst Tea Tribe adolescent girls in Dibrugarh district of Assam, India

OBJECTIVE Effect of Dietary diversity and other intervention in prevalence and determinants of an... more OBJECTIVE Effect of Dietary diversity and other intervention in prevalence and determinants of anaemia amongst tea tribe adolescent girls. DESIGN A community based before after intervention study was conducted covering 16 tea estates of Dibrugarh District, Assam. PROCEDURE Variables includes socio-demographic, environmental, anthropometry, history of present and past illness, clinical examination and laboratory investigation including haemoglobin, serum ferritin, haemoglobin typing and routine stool examination and dietary survey using 24 hour recall method and food frequency questionnaire. Interventions given were dietary diversification, health promotion by monthly NHED, cooking demonstration, cooking competition and kitchen garden promotion and counselling to improve IFA compliance and remove barriers and directly observed weekly IFA supplementation. SPSS and EpiInfo software, used to calculate of rates, ratios, chi-square test, Fisher Exact test and multiple logistic regression analysis.

Research paper thumbnail of Behavioural risk factors distribution of cardiovascular diseases and its association with normotension, prehypertension and hypertension amongst tea garden population in Dibrugarh district of Assam

Clinical Epidemiology and Global Health, 2016

c l i n i c a l e p i d e m i o l o g y a n d g l o b a l h e a l t h 4 (2 0 1 6) 4 5-5 0

Research paper thumbnail of Gestational Diabetes Mellitus- a Nested Case-Control Study

Journal of Evidence Based Medicine and Healthcare

BACKGROUND Prevalence of gestational diabetes mellitus is increasing around the world due to high... more BACKGROUND Prevalence of gestational diabetes mellitus is increasing around the world due to high prevalence of risk factors. It is responsible for various adverse pregnancy outcomes. The aim of the study is to study the occurrence of various maternal and foetal outcomes with gestational diabetes mellitus in a rural block of Assam. MATERIALS AND METHODS Present study was a part of larger cohort study. Here, one hundred and ninety three (193) cases and five hundred and seventy nine (579) matched controls were taken. Matching was done by age of the pregnant women. RESULTS Obesity was found twice among GDM cases than the controls (OR=2.40, CI=1.218-4.732, p=0.011). Prevalence of caesarean section was higher among GDM cases (p=0.009). Foetal macrosomia, NICU admission of newborn for >2 days, neonatal hypoglycaemia was significantly higher among GDM cases. CONCLUSION GDM causes significant complications of both mother and the newborn in terms of higher caesarean rate, macrosomia and neonatal hypoglycaemia and higher rate of admission in NICU >2 days.

Research paper thumbnail of Clinico-epidemiological profile of stroke patients admitted in a tertiary care Hospital of Assam

Clinical Epidemiology and Global Health

Research paper thumbnail of Determinants of hypertension amongst school going adolescents aged 13-15 yrs in Assam

Clinical Epidemiology and Global Health

Research paper thumbnail of Prevalence and Determinant of Obesity Amongst School Going Adolescent of Assam

Journal of Evidence Based Medicine and Healthcare

BACKGROUND The risk factors of cardiovascular diseases (CVD) in India are increasing at an alarmi... more BACKGROUND The risk factors of cardiovascular diseases (CVD) in India are increasing at an alarming rate for the last few decades. Obesity is one major risk factor of CVD which start very early in life, hence there is a need to determine prevalence and risk factor of obesity among younger age group so as to plan preventive strategies. MATERIALS AND METHODS A cluster sample with cluster size of 50 was taken from 16 schools to cover sample size of 800 with consideration of design effect. Socio-demographic, environmental, dietary, and anthropometric and laboratory risk factors were assessed in the studied population. RESULTS Obesity was prevalent in 5%, while overweight in 10%. Overweight and obesity was found to be more amongst students having educated parents (p<0.05). Strong association was seen amongst tobacco product users with overweight (p=0.000) and obesity (p=0.001), secondhand smoke exposures and depression (p<0.05), alcohol consumption, less fruit intake (weekly) (p<0.05), frequent animal food product consumer with both overweight (p=0.007) and obesity (p=0.008). Maximum obese (2.0%) students were daily consumer of sweet snacks (p=0.030). Overweight and obesity were strongly associated with number of meals served per day (p<0.05). Significant mean difference of systolic blood pressure, diastolic blood pressure and waist circumference between overweight and non-overweight and obese and non obese was seen. Second hand smoke exposure was associated with a statistically significant risk of overweight (OR=3.30, 95% CI = 1.754-6.210, p<0.05). Also hypertension was significantly associated with overweight and obesity with (OR=.30, 95% CI = 0.175-0.522, p<0.05) and (OR=0.25, 95% CI = 0.126-0.513, p<0.05) respectively.

Research paper thumbnail of Dietary Risk Factors of Metabolic Syndrome in Dibrugarh District of Assam

Journal of Evidence Based Medicine and Healthcare

BACKGROUND As India is considered as the diabetic capital of the world, a huge burden of undiagno... more BACKGROUND As India is considered as the diabetic capital of the world, a huge burden of undiagnosed Metabolic Syndrome (MetS) is a possibility. Early intervention can be planned if MetS can be detected early along with risk factor assessment to avert cardiovascular morbidities. The aim of this study was to assess the dietary risk factor of metabolic syndrome. MATERIALS AND METHODS Community based cross-sectional study was conducted in Dibrugarh District of Assam with multistep sampling. Study area, i.e. four rural sub-centres and two urban electoral blocks were selected randomly. From the list of population of selected area, the consenting eligible were included. Sample size was 1700 population with MetS. Socio-demographic information, World Health Organisation's STEPS questionnaire for behavioural risk factors along with dietary history, anthropometric assessment and laboratory investigations were conducted in three stages. Food frequency questionnaire was used for dietary assessment. Statistical analysis was done using rates, ratio, proportion, univariate and multivariate analysis. RESULTS MetS was 47.6% (1606 of 3372 screened). Mean age of study population was 47.1 ± 10.9 years. Behavioural risk factors like tobacco, alcohol consumption was high and significantly associated with metabolic syndrome (p= 0.000). Similarly financial stress, feeling stressed in last one year (p=0.034), lower physical activity level were also significantly associated with metS (p=0.000). Consumption of meat (p=0.000), egg (p=0.000), fast food (p=0.000), pickled vegetable (p=0.000) and sweet snacks (p=0.000) was found significantly higher amongst those with metabolic syndrome. Significant association was also seen with number of meals served per day and metS (p=0.000). CONCLUSION Dietary risk factors of cardiovascular diseases were rampant amongst persons with MetS. Dietary risk factor survey and counselling on healthy diet can be implemented in these population to give opportunity for early intervention.

Research paper thumbnail of A study of clinico-endoscopic profile of patient presenting with dyspepsia

The Journal of the Association of Physicians of India, 2016

Introduction: Dyspepsia is a common clinical symptom with prevalence of 5-20% of Outpatient (OPD)... more Introduction: Dyspepsia is a common clinical symptom with prevalence of 5-20% of Outpatient (OPD) consultation at tertiary care hospital. The cause is not detectable in more than half of the patients. The common organic causes include peptic ulcer, esophagitis, and malignancy. Aim: To study the clinical profile of patient presenting with dyspepsia in a tertiary care hospital of Assam, and correlate with endoscopic findings. Materials: This is a hospital based observational study conducted over an year. Adult patient with dyspepsia was included after informed consent. Clinical data and endoscopic findings of patients with dyspepsia were collected with the help of a structured questionnaire. Results: 158 patients with dyspepsia were assessed by Upper gastrointestinal (UGI) Endoscopy. Mean age of patient was 40.04 AE 14.3. 70.8% patients were males. 15.19% had history of smoking, 50.06% had history of tobacco consumption, 38.61% were alcoholic and history of NSAID consumption was seen in 9.49%. Alarm symptoms such as weight losss, anemia, UGI bleed were observed in 18.35% patients. Endoscopy revealed normal findings in 43.67% patients. Significant endoscopic findings were diagnosed in 56.32% patients. These included Peptic Ulcer in 25.95%, esophagitis in 4.43%, and UGI malignancy in 3.16%. Other significant lesions constituted less than 2%. Incidence of UGI malignancy was higher in patients more than 50 years. On comparing the endoscopic findings in patients of dyspepsia with alarm symptoms to those of dyspepsia without alarm symptoms, a statistical significance was observed with a p value of 0.013. Conclusion: In patients with dyspepsia presence of alarm symptoms is more significantly associated with organic lesion on endoscopy. Though the incidence of malignancy was low, endoscopy in patients more than 50 years may help in early diagnosis and reduced morbidity of these patients.

Research paper thumbnail of Determinants of metabolic syndrome (MetS) amongst persons living in Dibrugarh District of Assam

Clinical Epidemiology and Global Health, 2017

c l i n i c a l e p i d e m i o l o g y a n d g l o b a l h e a l t h 5

Research paper thumbnail of PS 11-30 Gaps in Hypertension Management in Type 2 Diabetes Patients in India

Journal of Hypertension, 2016

Research paper thumbnail of Evaluation of statin prescriptions in type 2 diabetes: India Heart Watch-2

BMJ Open Diabetes Research & Care, 2016

Background: Contemporary treatment guidelines advise statin use in all patients with diabetes for... more Background: Contemporary treatment guidelines advise statin use in all patients with diabetes for reducing coronary risk. Use of statins in patients with type 2 diabetes has not been reported from India. Methods: We performed a multisite (n=9) registrybased study among internists (n=3), diabetologists (n=3), and endocrinologists (n=3) across India to determine prescriptions of statins in patients with type 2 diabetes. Demographic and clinical details were obtained and prescriptions were audited for various medications with a focus on statins. Details of type of statin and dosage form (low, moderate, and high) were obtained. Patients were divided into categories based on presence of cardiovascular risk into low (no risk factors, n=1506), medium (≥1 risk factor, n=5425), and high (with vascular disease, n=1769). Descriptive statistics are presented. Results: Prescription details were available in 8699 (men 5292, women 3407). Statins were prescribed in 55.2% and fibrates in 9.2%. Statin prescription was significantly greater among diabetologists (64.4%) compared with internists (n=53.3%) and endocrinologists (46.8%; p<0.001). Atorvastatin was prescribed in 74.1%, rosuvastatin in 29.2%, and others in 3.0%. Statin prescriptions were lower in women (52.1%) versus men (57.2%; p<0.001) and in patients aged <40 years (34.3%), versus those aged 40-49 (49.7%), 50-59 (60.1%), and ≥60 years (62.2%; p<0.001). Low-dose statins were prescribed in 1.9%, moderate dose in 85.4%, and high dose in 12.7%. Statin prescriptions were greater in the high-risk group (58.0%) compared with those in the medium-risk (53.8%) and low-risk (56.8%) groups (p <0.001). High-dose statin prescriptions were similar in the highrisk (14.5%), medium-risk (11.8%), and low-risk (13.5%) groups (p=0.31). Conclusions: Statins are prescribed in only half of the clinic-based patients in India with type 2 diabetes. Prescription of high-dose statins is very low.

Research paper thumbnail of Effect of Directly Observed Iron Therapy (DOIT)

Indian Journal of Applied Research, Apr 1, 2013

Research paper thumbnail of iv) T G Mahanta, R Joshi, B N Mahanta, D Xavier, Prevalence of modifiable cardiovascular Risk Factors amongst Tea Garden and General Population in Dibrugarh, Assam, India, published in Journal of Epidemiology and Global Health (Elsavier Publication), June 2013 (Manuscript Number: JEGH-D-12-00037R2.)

Research paper thumbnail of Anaemia, its determinants and effect of different interventions amongst tea tribe adolescent girls living in Dibrugarh district of Assam

Indian Journal of Community Health, Dec 31, 2014

Research paper thumbnail of Effect of social and behavior change communication by using infotainment in community perception of adolescent girls for reproductive and sexual health care in high priority districts of Assam

Clinical Epidemiology and Global Health, 2015

Research paper thumbnail of Effectiveness of introducing home-based newborn care (HBNC) voucher system in Golaghat District of Assam

Clinical Epidemiology and Global Health, 2015

Research paper thumbnail of Postpartum Gangrene of All Four Limbs and Ergometrine Use

The objective was to study a twenty year old hindu female with post partum gangrene of all four l... more The objective was to study a twenty year old hindu female with post partum gangrene of all four limbs and to assess the effect of ergometrine use. Complete history, clinical examination and relevant investigative support for confirmatory diagnosis were done. A 20 yrs. female Hindu lady presented to emergency department of Assam medical college & hospital (mrd no 46472/11) on 06.11.11, with history of child birth 10 days ago, and presented to us with pain and blackening of the skin in all four limbs for two days. On examination there was presence of pallor with mild rise of temperature with absence of peripheral arterial pulsations in all the four limbs. Lower limbs showed symmetrical gangrene distal to mid cuff, and upper limbs showed asymmetrical areas of gangrene from the mid arm downward along with involvement of tip of the nose and its surrounding areas. The patient had a normal vaginal delivery conducted in a garden hospital and seven to eight days later she developed the above...

Research paper thumbnail of Citation

Anaemia, its determinants and effect of different interventions amongst tea tribe

Research paper thumbnail of KEYWORDSMetabolic Syndrome (MetS), Dietary Risk Factor, Food Frequency Questionnaire (FFQ), Cardiovascular Disease (CVD), Assam

Research paper thumbnail of Quality of Hypertension Management in Type 2 Diabetes in India: A Multisite Prescription Audit

Background and Objective Renin-angiotensin system (RAS) blockers (angiotensin converting enzyme i... more Background and Objective Renin-angiotensin system (RAS) blockers (angiotensin converting enzyme inhibitors ACEI, angiotensin receptor blockers, ARB) are preferred drugs to control hypertension among diabetic patients. To determine frequency of RAS blocker use in hypertensive patients with type 2 diabetes, we performed a multisite study in India. Methods We evaluated physician prescriptions in consecutive patients with type 2 diabetes at 9 sites in India. Details of socio-demographic characteristics, clinical findings and prescription medicines were obtained. Descriptive statistics are reported. Results Hypertension treatment details were available in 8056 of 8699 diabetic patients (4829 men, 3227 women). No hypertension was in 3300 (40.9%), hypertension in 3625 (45.0%), and hypertension with vascular disease in 1131 (14.0%). In diabetics with no hypertension, hypertension, and hypertension with vascular disease, respectively, prescriptions of antihypertensive drugs was: RAS blockers...

Research paper thumbnail of Dietary Diversity and its effect on anaemia prevalence amongst Tea Tribe adolescent girls in Dibrugarh district of Assam, India

OBJECTIVE Effect of Dietary diversity and other intervention in prevalence and determinants of an... more OBJECTIVE Effect of Dietary diversity and other intervention in prevalence and determinants of anaemia amongst tea tribe adolescent girls. DESIGN A community based before after intervention study was conducted covering 16 tea estates of Dibrugarh District, Assam. PROCEDURE Variables includes socio-demographic, environmental, anthropometry, history of present and past illness, clinical examination and laboratory investigation including haemoglobin, serum ferritin, haemoglobin typing and routine stool examination and dietary survey using 24 hour recall method and food frequency questionnaire. Interventions given were dietary diversification, health promotion by monthly NHED, cooking demonstration, cooking competition and kitchen garden promotion and counselling to improve IFA compliance and remove barriers and directly observed weekly IFA supplementation. SPSS and EpiInfo software, used to calculate of rates, ratios, chi-square test, Fisher Exact test and multiple logistic regression analysis.

Research paper thumbnail of Behavioural risk factors distribution of cardiovascular diseases and its association with normotension, prehypertension and hypertension amongst tea garden population in Dibrugarh district of Assam

Clinical Epidemiology and Global Health, 2016

c l i n i c a l e p i d e m i o l o g y a n d g l o b a l h e a l t h 4 (2 0 1 6) 4 5-5 0

Research paper thumbnail of Gestational Diabetes Mellitus- a Nested Case-Control Study

Journal of Evidence Based Medicine and Healthcare

BACKGROUND Prevalence of gestational diabetes mellitus is increasing around the world due to high... more BACKGROUND Prevalence of gestational diabetes mellitus is increasing around the world due to high prevalence of risk factors. It is responsible for various adverse pregnancy outcomes. The aim of the study is to study the occurrence of various maternal and foetal outcomes with gestational diabetes mellitus in a rural block of Assam. MATERIALS AND METHODS Present study was a part of larger cohort study. Here, one hundred and ninety three (193) cases and five hundred and seventy nine (579) matched controls were taken. Matching was done by age of the pregnant women. RESULTS Obesity was found twice among GDM cases than the controls (OR=2.40, CI=1.218-4.732, p=0.011). Prevalence of caesarean section was higher among GDM cases (p=0.009). Foetal macrosomia, NICU admission of newborn for >2 days, neonatal hypoglycaemia was significantly higher among GDM cases. CONCLUSION GDM causes significant complications of both mother and the newborn in terms of higher caesarean rate, macrosomia and neonatal hypoglycaemia and higher rate of admission in NICU >2 days.

Research paper thumbnail of Clinico-epidemiological profile of stroke patients admitted in a tertiary care Hospital of Assam

Clinical Epidemiology and Global Health

Research paper thumbnail of Determinants of hypertension amongst school going adolescents aged 13-15 yrs in Assam

Clinical Epidemiology and Global Health

Research paper thumbnail of Prevalence and Determinant of Obesity Amongst School Going Adolescent of Assam

Journal of Evidence Based Medicine and Healthcare

BACKGROUND The risk factors of cardiovascular diseases (CVD) in India are increasing at an alarmi... more BACKGROUND The risk factors of cardiovascular diseases (CVD) in India are increasing at an alarming rate for the last few decades. Obesity is one major risk factor of CVD which start very early in life, hence there is a need to determine prevalence and risk factor of obesity among younger age group so as to plan preventive strategies. MATERIALS AND METHODS A cluster sample with cluster size of 50 was taken from 16 schools to cover sample size of 800 with consideration of design effect. Socio-demographic, environmental, dietary, and anthropometric and laboratory risk factors were assessed in the studied population. RESULTS Obesity was prevalent in 5%, while overweight in 10%. Overweight and obesity was found to be more amongst students having educated parents (p<0.05). Strong association was seen amongst tobacco product users with overweight (p=0.000) and obesity (p=0.001), secondhand smoke exposures and depression (p<0.05), alcohol consumption, less fruit intake (weekly) (p<0.05), frequent animal food product consumer with both overweight (p=0.007) and obesity (p=0.008). Maximum obese (2.0%) students were daily consumer of sweet snacks (p=0.030). Overweight and obesity were strongly associated with number of meals served per day (p<0.05). Significant mean difference of systolic blood pressure, diastolic blood pressure and waist circumference between overweight and non-overweight and obese and non obese was seen. Second hand smoke exposure was associated with a statistically significant risk of overweight (OR=3.30, 95% CI = 1.754-6.210, p<0.05). Also hypertension was significantly associated with overweight and obesity with (OR=.30, 95% CI = 0.175-0.522, p<0.05) and (OR=0.25, 95% CI = 0.126-0.513, p<0.05) respectively.

Research paper thumbnail of Dietary Risk Factors of Metabolic Syndrome in Dibrugarh District of Assam

Journal of Evidence Based Medicine and Healthcare

BACKGROUND As India is considered as the diabetic capital of the world, a huge burden of undiagno... more BACKGROUND As India is considered as the diabetic capital of the world, a huge burden of undiagnosed Metabolic Syndrome (MetS) is a possibility. Early intervention can be planned if MetS can be detected early along with risk factor assessment to avert cardiovascular morbidities. The aim of this study was to assess the dietary risk factor of metabolic syndrome. MATERIALS AND METHODS Community based cross-sectional study was conducted in Dibrugarh District of Assam with multistep sampling. Study area, i.e. four rural sub-centres and two urban electoral blocks were selected randomly. From the list of population of selected area, the consenting eligible were included. Sample size was 1700 population with MetS. Socio-demographic information, World Health Organisation's STEPS questionnaire for behavioural risk factors along with dietary history, anthropometric assessment and laboratory investigations were conducted in three stages. Food frequency questionnaire was used for dietary assessment. Statistical analysis was done using rates, ratio, proportion, univariate and multivariate analysis. RESULTS MetS was 47.6% (1606 of 3372 screened). Mean age of study population was 47.1 ± 10.9 years. Behavioural risk factors like tobacco, alcohol consumption was high and significantly associated with metabolic syndrome (p= 0.000). Similarly financial stress, feeling stressed in last one year (p=0.034), lower physical activity level were also significantly associated with metS (p=0.000). Consumption of meat (p=0.000), egg (p=0.000), fast food (p=0.000), pickled vegetable (p=0.000) and sweet snacks (p=0.000) was found significantly higher amongst those with metabolic syndrome. Significant association was also seen with number of meals served per day and metS (p=0.000). CONCLUSION Dietary risk factors of cardiovascular diseases were rampant amongst persons with MetS. Dietary risk factor survey and counselling on healthy diet can be implemented in these population to give opportunity for early intervention.

Research paper thumbnail of A study of clinico-endoscopic profile of patient presenting with dyspepsia

The Journal of the Association of Physicians of India, 2016

Introduction: Dyspepsia is a common clinical symptom with prevalence of 5-20% of Outpatient (OPD)... more Introduction: Dyspepsia is a common clinical symptom with prevalence of 5-20% of Outpatient (OPD) consultation at tertiary care hospital. The cause is not detectable in more than half of the patients. The common organic causes include peptic ulcer, esophagitis, and malignancy. Aim: To study the clinical profile of patient presenting with dyspepsia in a tertiary care hospital of Assam, and correlate with endoscopic findings. Materials: This is a hospital based observational study conducted over an year. Adult patient with dyspepsia was included after informed consent. Clinical data and endoscopic findings of patients with dyspepsia were collected with the help of a structured questionnaire. Results: 158 patients with dyspepsia were assessed by Upper gastrointestinal (UGI) Endoscopy. Mean age of patient was 40.04 AE 14.3. 70.8% patients were males. 15.19% had history of smoking, 50.06% had history of tobacco consumption, 38.61% were alcoholic and history of NSAID consumption was seen in 9.49%. Alarm symptoms such as weight losss, anemia, UGI bleed were observed in 18.35% patients. Endoscopy revealed normal findings in 43.67% patients. Significant endoscopic findings were diagnosed in 56.32% patients. These included Peptic Ulcer in 25.95%, esophagitis in 4.43%, and UGI malignancy in 3.16%. Other significant lesions constituted less than 2%. Incidence of UGI malignancy was higher in patients more than 50 years. On comparing the endoscopic findings in patients of dyspepsia with alarm symptoms to those of dyspepsia without alarm symptoms, a statistical significance was observed with a p value of 0.013. Conclusion: In patients with dyspepsia presence of alarm symptoms is more significantly associated with organic lesion on endoscopy. Though the incidence of malignancy was low, endoscopy in patients more than 50 years may help in early diagnosis and reduced morbidity of these patients.

Research paper thumbnail of Determinants of metabolic syndrome (MetS) amongst persons living in Dibrugarh District of Assam

Clinical Epidemiology and Global Health, 2017

c l i n i c a l e p i d e m i o l o g y a n d g l o b a l h e a l t h 5

Research paper thumbnail of PS 11-30 Gaps in Hypertension Management in Type 2 Diabetes Patients in India

Journal of Hypertension, 2016

Research paper thumbnail of Evaluation of statin prescriptions in type 2 diabetes: India Heart Watch-2

BMJ Open Diabetes Research & Care, 2016

Background: Contemporary treatment guidelines advise statin use in all patients with diabetes for... more Background: Contemporary treatment guidelines advise statin use in all patients with diabetes for reducing coronary risk. Use of statins in patients with type 2 diabetes has not been reported from India. Methods: We performed a multisite (n=9) registrybased study among internists (n=3), diabetologists (n=3), and endocrinologists (n=3) across India to determine prescriptions of statins in patients with type 2 diabetes. Demographic and clinical details were obtained and prescriptions were audited for various medications with a focus on statins. Details of type of statin and dosage form (low, moderate, and high) were obtained. Patients were divided into categories based on presence of cardiovascular risk into low (no risk factors, n=1506), medium (≥1 risk factor, n=5425), and high (with vascular disease, n=1769). Descriptive statistics are presented. Results: Prescription details were available in 8699 (men 5292, women 3407). Statins were prescribed in 55.2% and fibrates in 9.2%. Statin prescription was significantly greater among diabetologists (64.4%) compared with internists (n=53.3%) and endocrinologists (46.8%; p<0.001). Atorvastatin was prescribed in 74.1%, rosuvastatin in 29.2%, and others in 3.0%. Statin prescriptions were lower in women (52.1%) versus men (57.2%; p<0.001) and in patients aged <40 years (34.3%), versus those aged 40-49 (49.7%), 50-59 (60.1%), and ≥60 years (62.2%; p<0.001). Low-dose statins were prescribed in 1.9%, moderate dose in 85.4%, and high dose in 12.7%. Statin prescriptions were greater in the high-risk group (58.0%) compared with those in the medium-risk (53.8%) and low-risk (56.8%) groups (p <0.001). High-dose statin prescriptions were similar in the highrisk (14.5%), medium-risk (11.8%), and low-risk (13.5%) groups (p=0.31). Conclusions: Statins are prescribed in only half of the clinic-based patients in India with type 2 diabetes. Prescription of high-dose statins is very low.

Research paper thumbnail of Effect of Directly Observed Iron Therapy (DOIT)

Indian Journal of Applied Research, Apr 1, 2013

Research paper thumbnail of iv) T G Mahanta, R Joshi, B N Mahanta, D Xavier, Prevalence of modifiable cardiovascular Risk Factors amongst Tea Garden and General Population in Dibrugarh, Assam, India, published in Journal of Epidemiology and Global Health (Elsavier Publication), June 2013 (Manuscript Number: JEGH-D-12-00037R2.)

Research paper thumbnail of Anaemia, its determinants and effect of different interventions amongst tea tribe adolescent girls living in Dibrugarh district of Assam

Indian Journal of Community Health, Dec 31, 2014

Research paper thumbnail of Effect of social and behavior change communication by using infotainment in community perception of adolescent girls for reproductive and sexual health care in high priority districts of Assam

Clinical Epidemiology and Global Health, 2015

Research paper thumbnail of Effectiveness of introducing home-based newborn care (HBNC) voucher system in Golaghat District of Assam

Clinical Epidemiology and Global Health, 2015

Research paper thumbnail of Postpartum Gangrene of All Four Limbs and Ergometrine Use

The objective was to study a twenty year old hindu female with post partum gangrene of all four l... more The objective was to study a twenty year old hindu female with post partum gangrene of all four limbs and to assess the effect of ergometrine use. Complete history, clinical examination and relevant investigative support for confirmatory diagnosis were done. A 20 yrs. female Hindu lady presented to emergency department of Assam medical college & hospital (mrd no 46472/11) on 06.11.11, with history of child birth 10 days ago, and presented to us with pain and blackening of the skin in all four limbs for two days. On examination there was presence of pallor with mild rise of temperature with absence of peripheral arterial pulsations in all the four limbs. Lower limbs showed symmetrical gangrene distal to mid cuff, and upper limbs showed asymmetrical areas of gangrene from the mid arm downward along with involvement of tip of the nose and its surrounding areas. The patient had a normal vaginal delivery conducted in a garden hospital and seven to eight days later she developed the above...