Nushrat Ovey | State university of Bangladesh, Dhaka (original) (raw)

Papers by Nushrat Ovey

Research paper thumbnail of Chemical and biological assays of Brassica rapa subsp. chinensis (L.) Hanelt

Bangladesh Journal of Botany

Bangladesh is in the tropical zone blessed with many plants and people of this country are depend... more Bangladesh is in the tropical zone blessed with many plants and people of this country are dependent on them to a greater extent for foods and medicines. Brassica is a broad genus and encompasses a lot of herbs. Among these, Brassica rapa subsp. chinensis (L.) Hanelt (Family-Brassicaceae) is famous in Bangladesh as vegetables. In order to explore the healing abilities of B. rapa subsp. chinensis, different chemical and biological assays have been conducted. Initially, the sun-dried powdered herb was extracted well with methanol and then partitioned with petroleum ether, carbon tetrachloride, chloroform and aqueous soluble fractions. All these extractives were subjected to brine shrimp lethality, free radical scavenging, phenolic content determination and antimicrobial assays. B. rapa subsp. chinensis exhibited various responses in the conducted assays depending on the extractives. These studies revealed the facts to consider this plant with medicinal qualities in addition to its gen...

Research paper thumbnail of In vitro Thrombolytic and Membrane Stabilizing Studies of Brassica rapa subsp. chinensis (L.) Hanelt

Bangladesh Pharmaceutical Journal, 2015

Brassica rapa subsp. chinensis (L.) Hanelt is a popular herb in Bangladesh. In the present studie... more Brassica rapa subsp. chinensis (L.) Hanelt is a popular herb in Bangladesh. In the present studies, the plant has been assessed to evaluate its in vitro thrombolytic and membrane stabilizing properties. Initially, the plant was collected, processed and extracted with methanol and the concentrated crude methanol extract was fractionated into petroleum ether, carbon tetrachloride, chloroform and aqueous soluble materials. All extractives, including the parent extract were subjected to thrombolytic and membrane stabilizing bioassays. In case of thrombolytic study, the carbon tetrachloride soluble fraction exhibited highest clot lysis. Here, streptokinase and distilled water were used as positive and negative control, respectively. However, in the assay for membrane stabilizing activity, the crude methanol extract along with other extractives were capable to inhibit hemolysis of erythrocyte membrane in hypotonic solution- and heat- induced conditions, which indicated anti-inflammatory p...

Research paper thumbnail of Analgesic And Anti-Inflammatory Activities Of <i>Asparagus africanus</i> Root Extract

African Journal of Traditional, Complementary and Alternative Medicines, 2008

The methanolic extract of the roots of Asparagus africanus Lam (Liliaceae) which contains mainly ... more The methanolic extract of the roots of Asparagus africanus Lam (Liliaceae) which contains mainly saponins and carbohydrate showed significant analgesic and anti-inflammatory activities (P&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;0.05) in the tail-flick/hot-plate test and egg albumen-induced rat paw oedema tests that were comparable to the test drugs (morphine 20 mg/kg and indomethacin 50 mg/kg respectively). These results indicate that the extract possesses analgesic and anti-inflammatory properties.

Research paper thumbnail of Analgesic and antidepressant activities of Brassica rapa subspecies chinensis (L.) Hanelt on Swiss-albino mice model

Bangladesh Medical Research Council Bulletin, 2016

Bangladesh being a subtropical country provides varieties of herbs and vegetables. Brassica is a ... more Bangladesh being a subtropical country provides varieties of herbs and vegetables. Brassica is a broad genus available in Bangladesh and it encompasses a lot of nutritive herbs. Among these, Brassica rapa subspecies chinensis (L.) Hanelt (Family-Brassicaceae) is popular in many parts of the world. In the quest of medicinal property, this plant was investigated here for observing analgesic and antidepressant activities in Swiss-albino mice model. The herb was extracted well with methanol and then assayed by acetic acid-induced writhing and tail immersion methods for analgesic action. Besides, thiopental sodium induced sleeping time test, tail suspension test and forced swim test were conducted for the evaluation of its antidepressant activity. The plant extract was orally administered to the mice at 200 and 400 mg/kg body weight and it exhibited significant analgesic and antidepressant activities in compare to the controlled groups. This is the first time comprehensive report for analgesic and antidepressant activities of this plant.

Research paper thumbnail of Analgesic and antidepressant activities of Brassica rapa subspecies chinensis (L.) Hanelt on Swiss-albino mice model

Analgesic and antidepressant activities of Brassica rapa subspecies chinensis (L.) Hanelt on Swiss-albino mice model , 2015

Bangladesh being a subtropical country provides varieties of herbs and vegetables. Brassica is a ... more Bangladesh being a subtropical country provides varieties of herbs and vegetables. Brassica is a broad genus available in Bangladesh and it encompasses a lot of nutritive herbs. Among these, Brassica rapa subspecies chinensis (L.) Hanelt (Family-Brassicaceae) is popular in many parts of the world. In the quest of medicinal property, this plant was investigated here for observing analgesic and antidepressant activities in Swiss-albino mice model. The herb was extracted well with methanol and then assayed by acetic acid-induced writhing and tail immersion methods for analgesic action. Besides, thiopental sodium induced sleeping time test, tail suspension test and forced swim test were conducted for the evaluation of its antidepressant activity. The plant extract was orally administered to the mice at 200 and 400 mg/kg body weight and it exhibited significant analgesic and antidepressant activities in compare to the controlled groups. This is the first time comprehensive report for analgesic and antidepressant activities of this plant.

Research paper thumbnail of CHEMICAL AND BIOLOGICAL ASSAYS OF BRASSICA RAPA SUBSP. CHINENSIS (L.) HANELT

Bangladesh is in the tropical zone blessed with many plants and people of this country are depend... more Bangladesh is in the tropical zone blessed with many plants and people of this country are dependent on them to a greater extent for foods and medicines. Brassica is a broad genus and encompasses a lot of herbs. Among these, Brassica rapa subsp. chinensis (L.) Hanelt (Family-Brassicaceae) is famous in Bangladesh as vegetables. In order to explore the healing abilities of B. rapa subsp. chinensis, different chemical and biological assays have been conducted. Initially, the sun-dried powdered herb was extracted well with methanol and then partitioned with petroleum ether, carbon tetrachloride, chloroform and aqueous soluble fractions. All these extractives were subjected to brine shrimp lethality, free radical scavenging, phenolic content determination and antimicrobial assays. B. rapa subsp. chinensis exhibited various responses in the conducted assays depending on the extractives. These studies revealed the facts to consider this plant with medicinal qualities in addition to its general identity as vegetables.

Research paper thumbnail of Analgesic and Anti Inflammatory Activities of Methanolic Extract of Fruit Rind of Citrullus Lanatus (THUNB)

Almost all diseases are associated with the inflammation and pain. The Present study was designed... more Almost all diseases are associated with the inflammation and pain. The Present study was designed to evaluate analgesic and anti inflammatory potentialities of methanolic extract of Cirtrullus lanatus rind which belongs to Cucurbitaceae family. Potent analgesic activity was observed (p<0.05) in extract 400mg/kg by 66.45% inhibition of writhing reflex and mild (50.63% inhibition) activity was observed in 200mg/kg compare to inhibition of 82.91% of standard Diclofenac 10 mg/kg. On the other hand, anti-inflammatory effect was remarkable (p<0.05) with 400mg crude compare with Standard Diclofenac 5 mg/kg body weight. Dunet test represents 46% reduction of paw edema compare to standard of 56.71%. Preliminary phytochemical screening of the plant extract showed the presence of Glycosides, saponins, flavonoids, steroids and protein were present in the rind of Citrullus lanatus one of which has analgesic, anti inflammatory properties. These provide scientific evidence to support the isolation and development of biologically active components as analgesic and anti-inflammatory agents.

Research paper thumbnail of In vitro Thrombolytic and Membrane Stabilizing Studies of Brassica rapa subsp. chinensis (L.) Hanelt

Brassica rapa subsp. chinensis (L.) Hanelt is a popular herb in Bangladesh. In the present studie... more Brassica rapa subsp. chinensis (L.) Hanelt is a popular herb in Bangladesh. In the present studies, the plant has been assessed to evaluate its in vitro thrombolytic and membrane stabilizing properties. Initially, the plant was collected, processed and extracted with methanol and the concentrated crude methanol extract was fractionated into petroleum ether, carbon tetrachloride, chloroform and aqueous soluble materials. All extractives, including the parent extract were subjected to thrombolytic and membrane stabilizing bioassays. In case of thrombolytic study, the carbon tetrachloride soluble fraction exhibited highest clot lysis. Here, streptokinase and distilled water were used as positive and negative control, respectively. However, in the assay for membrane stabilizing activity, the crude methanol extract along with other extractives were capable to inhibit hemolysis of erythrocyte membrane in hypotonic solution-and heat-induced conditions, which indicated anti-inflammatory property of the samples. Acetyl salicylic acid was used as standard drug in this assay. This represents the first report of thrombolytic and membrane stabilizing activities of B. rapa subsp. chinensis.

Research paper thumbnail of Chemical and biological assays of Brassica rapa subsp. chinensis (L.) Hanelt

Bangladesh Journal of Botany

Bangladesh is in the tropical zone blessed with many plants and people of this country are depend... more Bangladesh is in the tropical zone blessed with many plants and people of this country are dependent on them to a greater extent for foods and medicines. Brassica is a broad genus and encompasses a lot of herbs. Among these, Brassica rapa subsp. chinensis (L.) Hanelt (Family-Brassicaceae) is famous in Bangladesh as vegetables. In order to explore the healing abilities of B. rapa subsp. chinensis, different chemical and biological assays have been conducted. Initially, the sun-dried powdered herb was extracted well with methanol and then partitioned with petroleum ether, carbon tetrachloride, chloroform and aqueous soluble fractions. All these extractives were subjected to brine shrimp lethality, free radical scavenging, phenolic content determination and antimicrobial assays. B. rapa subsp. chinensis exhibited various responses in the conducted assays depending on the extractives. These studies revealed the facts to consider this plant with medicinal qualities in addition to its gen...

Research paper thumbnail of In vitro Thrombolytic and Membrane Stabilizing Studies of Brassica rapa subsp. chinensis (L.) Hanelt

Bangladesh Pharmaceutical Journal, 2015

Brassica rapa subsp. chinensis (L.) Hanelt is a popular herb in Bangladesh. In the present studie... more Brassica rapa subsp. chinensis (L.) Hanelt is a popular herb in Bangladesh. In the present studies, the plant has been assessed to evaluate its in vitro thrombolytic and membrane stabilizing properties. Initially, the plant was collected, processed and extracted with methanol and the concentrated crude methanol extract was fractionated into petroleum ether, carbon tetrachloride, chloroform and aqueous soluble materials. All extractives, including the parent extract were subjected to thrombolytic and membrane stabilizing bioassays. In case of thrombolytic study, the carbon tetrachloride soluble fraction exhibited highest clot lysis. Here, streptokinase and distilled water were used as positive and negative control, respectively. However, in the assay for membrane stabilizing activity, the crude methanol extract along with other extractives were capable to inhibit hemolysis of erythrocyte membrane in hypotonic solution- and heat- induced conditions, which indicated anti-inflammatory p...

Research paper thumbnail of Analgesic And Anti-Inflammatory Activities Of <i>Asparagus africanus</i> Root Extract

African Journal of Traditional, Complementary and Alternative Medicines, 2008

The methanolic extract of the roots of Asparagus africanus Lam (Liliaceae) which contains mainly ... more The methanolic extract of the roots of Asparagus africanus Lam (Liliaceae) which contains mainly saponins and carbohydrate showed significant analgesic and anti-inflammatory activities (P&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;0.05) in the tail-flick/hot-plate test and egg albumen-induced rat paw oedema tests that were comparable to the test drugs (morphine 20 mg/kg and indomethacin 50 mg/kg respectively). These results indicate that the extract possesses analgesic and anti-inflammatory properties.

Research paper thumbnail of Analgesic and antidepressant activities of Brassica rapa subspecies chinensis (L.) Hanelt on Swiss-albino mice model

Bangladesh Medical Research Council Bulletin, 2016

Bangladesh being a subtropical country provides varieties of herbs and vegetables. Brassica is a ... more Bangladesh being a subtropical country provides varieties of herbs and vegetables. Brassica is a broad genus available in Bangladesh and it encompasses a lot of nutritive herbs. Among these, Brassica rapa subspecies chinensis (L.) Hanelt (Family-Brassicaceae) is popular in many parts of the world. In the quest of medicinal property, this plant was investigated here for observing analgesic and antidepressant activities in Swiss-albino mice model. The herb was extracted well with methanol and then assayed by acetic acid-induced writhing and tail immersion methods for analgesic action. Besides, thiopental sodium induced sleeping time test, tail suspension test and forced swim test were conducted for the evaluation of its antidepressant activity. The plant extract was orally administered to the mice at 200 and 400 mg/kg body weight and it exhibited significant analgesic and antidepressant activities in compare to the controlled groups. This is the first time comprehensive report for analgesic and antidepressant activities of this plant.

Research paper thumbnail of Analgesic and antidepressant activities of Brassica rapa subspecies chinensis (L.) Hanelt on Swiss-albino mice model

Analgesic and antidepressant activities of Brassica rapa subspecies chinensis (L.) Hanelt on Swiss-albino mice model , 2015

Bangladesh being a subtropical country provides varieties of herbs and vegetables. Brassica is a ... more Bangladesh being a subtropical country provides varieties of herbs and vegetables. Brassica is a broad genus available in Bangladesh and it encompasses a lot of nutritive herbs. Among these, Brassica rapa subspecies chinensis (L.) Hanelt (Family-Brassicaceae) is popular in many parts of the world. In the quest of medicinal property, this plant was investigated here for observing analgesic and antidepressant activities in Swiss-albino mice model. The herb was extracted well with methanol and then assayed by acetic acid-induced writhing and tail immersion methods for analgesic action. Besides, thiopental sodium induced sleeping time test, tail suspension test and forced swim test were conducted for the evaluation of its antidepressant activity. The plant extract was orally administered to the mice at 200 and 400 mg/kg body weight and it exhibited significant analgesic and antidepressant activities in compare to the controlled groups. This is the first time comprehensive report for analgesic and antidepressant activities of this plant.

Research paper thumbnail of CHEMICAL AND BIOLOGICAL ASSAYS OF BRASSICA RAPA SUBSP. CHINENSIS (L.) HANELT

Bangladesh is in the tropical zone blessed with many plants and people of this country are depend... more Bangladesh is in the tropical zone blessed with many plants and people of this country are dependent on them to a greater extent for foods and medicines. Brassica is a broad genus and encompasses a lot of herbs. Among these, Brassica rapa subsp. chinensis (L.) Hanelt (Family-Brassicaceae) is famous in Bangladesh as vegetables. In order to explore the healing abilities of B. rapa subsp. chinensis, different chemical and biological assays have been conducted. Initially, the sun-dried powdered herb was extracted well with methanol and then partitioned with petroleum ether, carbon tetrachloride, chloroform and aqueous soluble fractions. All these extractives were subjected to brine shrimp lethality, free radical scavenging, phenolic content determination and antimicrobial assays. B. rapa subsp. chinensis exhibited various responses in the conducted assays depending on the extractives. These studies revealed the facts to consider this plant with medicinal qualities in addition to its general identity as vegetables.

Research paper thumbnail of Analgesic and Anti Inflammatory Activities of Methanolic Extract of Fruit Rind of Citrullus Lanatus (THUNB)

Almost all diseases are associated with the inflammation and pain. The Present study was designed... more Almost all diseases are associated with the inflammation and pain. The Present study was designed to evaluate analgesic and anti inflammatory potentialities of methanolic extract of Cirtrullus lanatus rind which belongs to Cucurbitaceae family. Potent analgesic activity was observed (p<0.05) in extract 400mg/kg by 66.45% inhibition of writhing reflex and mild (50.63% inhibition) activity was observed in 200mg/kg compare to inhibition of 82.91% of standard Diclofenac 10 mg/kg. On the other hand, anti-inflammatory effect was remarkable (p<0.05) with 400mg crude compare with Standard Diclofenac 5 mg/kg body weight. Dunet test represents 46% reduction of paw edema compare to standard of 56.71%. Preliminary phytochemical screening of the plant extract showed the presence of Glycosides, saponins, flavonoids, steroids and protein were present in the rind of Citrullus lanatus one of which has analgesic, anti inflammatory properties. These provide scientific evidence to support the isolation and development of biologically active components as analgesic and anti-inflammatory agents.

Research paper thumbnail of In vitro Thrombolytic and Membrane Stabilizing Studies of Brassica rapa subsp. chinensis (L.) Hanelt

Brassica rapa subsp. chinensis (L.) Hanelt is a popular herb in Bangladesh. In the present studie... more Brassica rapa subsp. chinensis (L.) Hanelt is a popular herb in Bangladesh. In the present studies, the plant has been assessed to evaluate its in vitro thrombolytic and membrane stabilizing properties. Initially, the plant was collected, processed and extracted with methanol and the concentrated crude methanol extract was fractionated into petroleum ether, carbon tetrachloride, chloroform and aqueous soluble materials. All extractives, including the parent extract were subjected to thrombolytic and membrane stabilizing bioassays. In case of thrombolytic study, the carbon tetrachloride soluble fraction exhibited highest clot lysis. Here, streptokinase and distilled water were used as positive and negative control, respectively. However, in the assay for membrane stabilizing activity, the crude methanol extract along with other extractives were capable to inhibit hemolysis of erythrocyte membrane in hypotonic solution-and heat-induced conditions, which indicated anti-inflammatory property of the samples. Acetyl salicylic acid was used as standard drug in this assay. This represents the first report of thrombolytic and membrane stabilizing activities of B. rapa subsp. chinensis.