Saeid Aslanabadi | Tabriz University Of Medical Sciences (original) (raw)

Papers by Saeid Aslanabadi

Research paper thumbnail of Relationship between attention‐deficit/hyperactivity disorder and trans fatty acids intake in female adolescents

Acta Paediatrica, 2012

1.Department of Family Medicine, Chung-Ang University Medical Center, Chung-Ang University Colleg... more 1.Department of Family Medicine, Chung-Ang University Medical Center, Chung-Ang University College of Medicine, Seoul, Korea 2.Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Korea 3.Department of Biostatistics, Yonsei University College of Medicine, Seoul, Korea 4.Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University College of Medicine, Seoul, Korea 5.Department of Family Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea 6.Clinical Research Center for Rheumatoid Arthritis, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea 7.Department of Family Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea

Research paper thumbnail of Pure Yolk Sac (Endodermal Sinus) Tumor of the Liver: A Case Report

Iranian Journal of Radiology, Jun 30, 2009

Hepatic tumors are rare in children. About 50%-60% of these tumors are malignant. 65% of the live... more Hepatic tumors are rare in children. About 50%-60% of these tumors are malignant. 65% of the liver malignancies are hepatoblastomas and most of the remainder are hepatocellular carcinomas. Yolk sac tumor (YST) is an extremely rare tumor of the liver. We report on a hepatic yolk sac tumor in a 15-month-old girl who presented with acute abdomen. She was diagnosed initially as intussusception, while ultrasonography and CT-scan indicated a liver mass. Finally, yolk sac tumor was diagnosed surgically and histopathologically.

Research paper thumbnail of A Survey of Early Oral Feeding in Intestinal Anastomosis in Children Admitted in Tabriz Children Hospital

Research paper thumbnail of Prevalence of the Congenital Heart Diseases (CHD) in Patients with Esophageal Atresia and Its Influence on Surgical Outcome

Medical journal of Tabriz University of Medical Sciences and Health Services, Sep 22, 2008

Background and Objectives: Esophageal atresia is one of the most common congenital anomalies. Coi... more Background and Objectives: Esophageal atresia is one of the most common congenital anomalies. Coincident of anomalies in organs other than esophagus such as the heart is a common finding in these patients. The purpose of this study was to evaluate the prevalence of ...

Research paper thumbnail of The Effect of Bupivacaine-Clonidine Combination in Quality and Duration of Caudal Block in Children between 2-7 Years Old

Medical journal of Tabriz University of Medical Sciences and Health Services, Jun 23, 2008

Research paper thumbnail of Comparing Multiple-Choice Questions Quality Parameters of Pediatric, General Surgery, Internal Medicine and Genecology and Obstetrics Residency Tests in Preboard and Promotion Examinations of Tabriz University of Medical Sciences and National Board Examination in 2010 and 2011

Journal of Medical Education Development, 2015

Research paper thumbnail of A Case of Giant Gastric Trichobezoar

Trichobezoar is an unusual form of bezoar found in the digestive tract, mostly in the stomach. Th... more Trichobezoar is an unusual form of bezoar found in the digestive tract, mostly in the stomach. The patient is often a female in her adolescence who pulls out and swallows her hair. This habit could stem from anxiety and the trichotillomania disorder. These hairs accumulate in the stomach and cause gastrointestinal symptoms. Our patient is a 14-year-old girl who came to us complaining of abdominal pain. Upon further evaluation by ultrasonography and endoscopy, trichobezoar was diagnosed. Laparotomy and gastrotomy were performed,and a large bezoar was removed. Although the occurrence of trichobezoar is rare, surgeons should always consider the situation in patients with vague gastrointestinal symptoms and psychological problems, especially in young female individuals.

Research paper thumbnail of Does Severity of Attention Deficit /Hyperactivity Disorder impact Trauma in Children?

Journal of Analytical Research in Clinical Medicine, 2017

Introduction: Attention deficit hyperactivity disorder (ADHD) is a chronic neurodevelopmental dis... more Introduction: Attention deficit hyperactivity disorder (ADHD) is a chronic neurodevelopmental disorder with high heritability. It is the most common childhood mental disorder. The key aspects of ADHD may put the affected children at risk for different traumatic experiences. Therefore, this study was conducted to investigate the relationship between the severity of trauma and ADHD symptoms in children. Methods: In this descriptive-correlational study, the target population included 90 children aged 6-12 years old, visiting Imam Reza, Children, Sina, and Shohada Hospitals in Tabriz, Iran. The severity of trauma was assessed, using placebo transdermal system (PTS), and the ADHD symptoms were evaluated, using Conners' Parent Rating Scale. To rule out other psychiatric disorders, the Child Symptoms Inventory-4 (CSI-4) was employed. Results: Results showed a significant positive correlation between the severity of trauma and ADHD, hyperactivity, oppositional/impulsivity, and attention-deficit scores (P < 0.01). In addition, results from the independent t-test suggested a significance difference between the ADHD and non-ADHD children in terms of the severity of trauma. Conclusion: There was a significant relationship between the symptoms of ADHD and the severity of trauma in children, in a way that the scores of the aforementioned variables improved with increasing the severity of trauma. Regarding the profound effects of trauma on human and financial resources, required measures should be taken for making house and school settings safe for such children.

Research paper thumbnail of Comparison of Open and Ultrasound-Guided Placement of Central Venous Catheter in Children Weighing Less Than Five Kilograms; A Randomized Clinical Trial

Academic Radiology, Jul 1, 2023

Research paper thumbnail of Study on Effectiveness of Barium Enema in the Diagnosis of Hirschsprung Disease

Research paper thumbnail of Twenty Years of Experience in Management of Intussusception: Saline Enema Reduction with Ultrasound Guidance

Çocuk cerrahisi dergisi, 2021

Research paper thumbnail of Splenogonadal Fusion, a Rare Benign Lesion of Testis

Medical journal of Tabriz University of Medical Sciences and Health Services, Dec 26, 2011

Research paper thumbnail of A Comparative Study of Single Scrotal Incision Orchiopexy of Children with Palpable Low-Lying Undescended Testis with Traditional Inguinal Method

Advances in pediatric surgery, 2019

Purpose: Undescended testis (UDT) is a developmental defect in which one or both testicles do not... more Purpose: Undescended testis (UDT) is a developmental defect in which one or both testicles do not arrive in the scrotum. Its prevalence at birth and one year after is 2%-4% and less than 1%, respectively. Currently, surgery is recommended to treat congenital cryptorchidism in order to prevent testicular degeneration. Classic method is performed via incision in inguinal and scrotum and the new method is done via incision in scrotum. Method: Sixty male participants with 65 UDT undergoing surgery were randomly assigned to scrotal incision (n=31) and classic inguinal incision methods (n=34). Patients were followed for 6 months and testicular atrophy, infection, recurrence, and duration of surgery were compared between two groups. Results: Scrotal incision compared to classic incision method had significantly lower duration of surgery (19.06±2.96 minutes vs. 30±10.42 minutes; p=0.002) and recurrence during follow-up (0 vs. 5 cases; p=0.026). There was only one surgical site infection in the scrotal incision method. There were hematoma and post-operative swelling in 13.3% of cases after scrotal incision method. Conclusion: Scrotal incision is an alternative method for the UDT with lower duration of surgery, lower recurrence rate, and better cosmetic results.

Research paper thumbnail of A Study on Diagnostic and Therapeutic Procedures in Infants and Children with Intussusception at Childern Hospital in Tabriz

Medical Journal of Tabriz University of Medical Sciences, 2004

Research paper thumbnail of Helicobacter Pylori and Infantile Hypertrophic Pyloric Stenosis

Medical journal of Tabriz University of Medical Sciences and Health Services, Apr 26, 2011

Background: Recently, it has been suggested that Helicobacter pylori might be a cause of some cas... more Background: Recently, it has been suggested that Helicobacter pylori might be a cause of some cases of infantile hypertrophic pyloric stenosis (IHPS) in infancy on the basis of its epidemiologic and clinical features. We performed this study to evaluate the possible relationship between IHPS and H. pylori. Design: In consecutive infants with IHPS, we performed upper gastrointestinal endoscopy with biopsy before pyloromyotomy. The endoscopic appearance of the pylorus was noted to validate endoscopic features of IHPS. Results: Sixteen infants, 15 male, 14 white, mean age 42 days, range 21 to 104 days, were studied. The index case had chronic active gastritis on biopsy with organisms suspicious for H. pylori. Four others had chronic active gastritis, six more had focal or mild chronic gastritis, five were normal, and none had H. pylori on histology or immune histochemical staining in selected cases. All patients had negative rapid urease test. Most common endoscopic findings of IHPS were thickened prominent asymmetric pyloric folds and pin-hole pylorus that could not be intubated by the pediatric endoscope. Conclusion: H. pylori was not specifically identified in our patients with IHPS. The presence of H. pylori-like organisms in the gastric mucosa in our index case and finding of chronic active gastritis in several others may indicate the possibility of an acquired infectious etiology for IHPS. JPGN 42:262Y264, 2006.

Research paper thumbnail of The relationship between attention-deficit/ hyperactivity disorder and trauma in adolescents

Journal of emergency practice and trauma, Jul 1, 2017

Introduction Attention-deficit/hyperactivity disorder (ADHD) is one of the most common disorders ... more Introduction Attention-deficit/hyperactivity disorder (ADHD) is one of the most common disorders which happens mostly at school years with symptoms like inattentiveness, hyperactivity, impulsive behaviors, or a combination of these symptoms (1). It may impair cognitive abilities and psycho-social functions. Not only it can have some effects on children and adolescents' life, but also it can affect the family's quality of life (2).The Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5) specifies this disorder based on two aspects of symptoms: 1) the aspect of attention deficiency and 2) hyperactivity and impulsiveness. Thus, it is necessary to control these symptoms in adolescents as they can cause some problems at school or in social places for them. Also, DSM5 introduces three subcategories (presentations) for ADHD: (a) inattentive, (b) hyperactive/impulsive and (c) combined (3). ADHD children may experience significant problems in adaptability because of their expected level of development or growth with their chronological age (4). In 60% of cases, symptoms rests until the adulthood stage and most cases are concomitant with other mental disorders such as depression, anxiety, obsession, learning disabilities, bipolar disorder, and so on (5-7). In some studies, the education failure and background emotional problems such as anxiety and depression were reported

Research paper thumbnail of Diagnostic Accuracy of Doppler Ultrasonography in Differentiation between Malignant and Benign Cervical Lymphadenopathies in Pediatric Age Group

Pakistan Journal of Biological Sciences, Jul 15, 2010

Cervical lymphadenopathy is a relatively common finding in pediatric age group and is caused by a... more Cervical lymphadenopathy is a relatively common finding in pediatric age group and is caused by a wide spectrum of diseases from transient infections to malignancies especially lymphomas. The present study was aimed at evaluating the diagnostic performance of grey-scale ultrasonography, color Doppler ultrasonography and power Doppler ultrasonography in differentiation of reactively and metastatically enlarged cervical lymph nodes in pediatric age group. Fifty children with cervical lymphadenopathies were assessed by ultrasonographic methods. In each patient, the longest (L) and transverse (T) diameters, L/T ratio and presence or absence of the normal hilar pattern were checked by grey-scale ultrasonography. Spectral parameters (resistive and pulsatility indices) and vascular distribution pattern of nodes were recorded by color and power Doppler ultrasonography, respectively. Following the ultrasonographic evaluations, biopsy and/or clinical follow up was applied for six months, based on the clinical and paraclinical findings. Statistical analyses were performed by chi-square test, independent t-test and receiver operator characteristic curves. The mean age of patients was 12.42 +/- 2.42 years. Twenty eight patients (56%) had malignant enlargement of lymph nodes. The mean value of L/T ratio in malignant group was 1.70 +/- 0.22 and 2.40 +/- 0.38 in non-malignant nodes (p &amp;amp;amp;amp;lt; 0.001). Sensitivity, specificity and accuracy of combined grey-scale and power Doppler ultrasonography were 70, 86 and 81%, respectively. Combination of grey-scale and power Doppler ultrasonography is recommended for the differentiation between the malignant and benign lymphadenopathies in children. Moreover, our findings revealed no diagnostic role of color Doppler ultrasonography in the selection of malignant cervical lymph nodes in children.

Research paper thumbnail of Reduction of Neonatal Gastroschisisa with or Without General Anesthesia

Medical journal of Tabriz University of Medical Sciences and Health Services, Sep 24, 2013

Backgrounds and Objectives: Gastroschisis is a congenital defect in anterior abdominal wall on ri... more Backgrounds and Objectives: Gastroschisis is a congenital defect in anterior abdominal wall on right side of umbilicus and abdominal viscera protrude from this defect. Reduction under general anesthesia is the routine method of treatment. Recently, to avoid complications of general anesthesia and intubation, reduction without anesthesia has been recommended. Materials and Methods: This study was conducted in Tabriz, Shahid Beheshti, Mashhad, Shiraz and Ghazvin medical universities between 2010 to 2012 all neonates with Gastroschisis were included and their parents were signed consent. Exclusion criteria were peritonitis, major anomalies and intestinal atresia. Then Gastroschisis was treated with or without general anesthesia. Results: Eighteen infants with Gastroschisis were enrolled the study. 8 cases treated without general anesthesia and 10 cases were reduced under general anesthesia. Infants in the second group had an increased duration of hospitalization, need for mechanical and prolonge, duration of TPN, need for subsequent surgical procedure and prolonge duration of stay in NICU, although it is not significant. Conclusion: Result of this study demonstrate whose patients was reduced without general anesthesia inward, have better outcomes to those whose bowel was reduced under general anesthesia and it seem inward reduction is a safe and effective method for treatment in this anomaly.

Research paper thumbnail of Diagnostic value of procalcitonin and apo-e in extrahepatic biliary atresia

PubMed, Oct 1, 2014

Objective: Extrahepatic biliary atresia (EHBA) is one of the main causes of neonatal cholestasis.... more Objective: Extrahepatic biliary atresia (EHBA) is one of the main causes of neonatal cholestasis. Its early diagnosis could increase the survival of the infants with early surgery. We evaluated the diagnostic accuracy of procalcitonin and apolipoprotein E (Apo-E) levels in infants with and without EHBA. Methods: This prospective study included 18 infants with EHBA and 15 infants with other causes of cholestasis. Blood samples were taken from each patient and different markers including procalcitonin and Apo-E levels were measured. ROC analysis was used to define sensitivity, specificity, positive and negative predictive value (PPV and NPV) for procalcitonin and Apo-E. Findings : There was a significantly positive correlation between Apo-E and SGOT (r=0.37, P=0.03), SGPT (r=0.38, P=0.02) and GGT (r=0.38, P=0.02), and an inverse correlation between procalcitonin and GGT (r=-0.45, P=0.01). Area under curve (AUC) for procalcitonin was 0.69 (P=0.05) with cut-point of 0.735 ng/ml. The sensitivity, specificity, PPV and NPV was 67%, 61%, 69% and 59%, respectively. AUC for Apo-E was 0.68 (P=0.06) for cut-point of 61.25 ng/ml with sensitivity, specificity, PPV and NPV of 67%, 67%, 71% and 67%, respectively. Conclusion: Both PCT and Apo-E have relatively good accuracy in diagnosing EHBA cases; we could not rely on these markers for diagnosis of EHBA, however, combinations of these biomarkers with other markers and imaging tests could improve their accuracy and may help to achieve a rapid and accurate diagnosis of EHBA.

Research paper thumbnail of Congenital diaphragmatic hernia: Prognostic value of hernia sac and size of defect

Journal of research in clinical medicine, Mar 12, 2022

Introduction: Congenital diaphragmatic hernia (CDH) is a congenital malformation with challenging... more Introduction: Congenital diaphragmatic hernia (CDH) is a congenital malformation with challenging management. The aim of this study was to evaluate the effect of the presence of hernia sac and defect size on the prognosis of CDH in Tabriz children's hospital. Methods: In this prospective study, all the infants with the diagnosis of CDH that were admitted to the Tabriz children's hospital since 2016-2019 were enrolled. The presence or absence of a hernia sac was evaluated, and the largest diameter on diaphragmatic defect was measured before the repair. Postoperative outcomes, including instability, duration of mechanical ventilation, mortality rate, or hospital discharge were obtained and analyzed. Results: Over the study period, 30 patients with CDH met the inclusion criteria, consisting of 15 males and 15 females. Fifteen cases were diagnosed during the first 24 hours of life and 16 cases experienced hypoxia in the first hour after birth. Defect size was significantly smaller in survived patients (P = 0.041). Postoperative death occurred in 9 (42.85%) patients without a hernia sac. Results showed that none of the cases with hernia sac expired (P = 0.035). Conclusion: In our study, the presence of the hernia sac was related to a lower postoperative mortality rate. Defect size in survived group was also smaller. It can be suggested that the presence of hernia sac and lower diameter of defect size act as good prognostic factors in the outcome of patients with CDH.

Research paper thumbnail of Relationship between attention‐deficit/hyperactivity disorder and trans fatty acids intake in female adolescents

Acta Paediatrica, 2012

1.Department of Family Medicine, Chung-Ang University Medical Center, Chung-Ang University Colleg... more 1.Department of Family Medicine, Chung-Ang University Medical Center, Chung-Ang University College of Medicine, Seoul, Korea 2.Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Korea 3.Department of Biostatistics, Yonsei University College of Medicine, Seoul, Korea 4.Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University College of Medicine, Seoul, Korea 5.Department of Family Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea 6.Clinical Research Center for Rheumatoid Arthritis, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea 7.Department of Family Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea

Research paper thumbnail of Pure Yolk Sac (Endodermal Sinus) Tumor of the Liver: A Case Report

Iranian Journal of Radiology, Jun 30, 2009

Hepatic tumors are rare in children. About 50%-60% of these tumors are malignant. 65% of the live... more Hepatic tumors are rare in children. About 50%-60% of these tumors are malignant. 65% of the liver malignancies are hepatoblastomas and most of the remainder are hepatocellular carcinomas. Yolk sac tumor (YST) is an extremely rare tumor of the liver. We report on a hepatic yolk sac tumor in a 15-month-old girl who presented with acute abdomen. She was diagnosed initially as intussusception, while ultrasonography and CT-scan indicated a liver mass. Finally, yolk sac tumor was diagnosed surgically and histopathologically.

Research paper thumbnail of A Survey of Early Oral Feeding in Intestinal Anastomosis in Children Admitted in Tabriz Children Hospital

Research paper thumbnail of Prevalence of the Congenital Heart Diseases (CHD) in Patients with Esophageal Atresia and Its Influence on Surgical Outcome

Medical journal of Tabriz University of Medical Sciences and Health Services, Sep 22, 2008

Background and Objectives: Esophageal atresia is one of the most common congenital anomalies. Coi... more Background and Objectives: Esophageal atresia is one of the most common congenital anomalies. Coincident of anomalies in organs other than esophagus such as the heart is a common finding in these patients. The purpose of this study was to evaluate the prevalence of ...

Research paper thumbnail of The Effect of Bupivacaine-Clonidine Combination in Quality and Duration of Caudal Block in Children between 2-7 Years Old

Medical journal of Tabriz University of Medical Sciences and Health Services, Jun 23, 2008

Research paper thumbnail of Comparing Multiple-Choice Questions Quality Parameters of Pediatric, General Surgery, Internal Medicine and Genecology and Obstetrics Residency Tests in Preboard and Promotion Examinations of Tabriz University of Medical Sciences and National Board Examination in 2010 and 2011

Journal of Medical Education Development, 2015

Research paper thumbnail of A Case of Giant Gastric Trichobezoar

Trichobezoar is an unusual form of bezoar found in the digestive tract, mostly in the stomach. Th... more Trichobezoar is an unusual form of bezoar found in the digestive tract, mostly in the stomach. The patient is often a female in her adolescence who pulls out and swallows her hair. This habit could stem from anxiety and the trichotillomania disorder. These hairs accumulate in the stomach and cause gastrointestinal symptoms. Our patient is a 14-year-old girl who came to us complaining of abdominal pain. Upon further evaluation by ultrasonography and endoscopy, trichobezoar was diagnosed. Laparotomy and gastrotomy were performed,and a large bezoar was removed. Although the occurrence of trichobezoar is rare, surgeons should always consider the situation in patients with vague gastrointestinal symptoms and psychological problems, especially in young female individuals.

Research paper thumbnail of Does Severity of Attention Deficit /Hyperactivity Disorder impact Trauma in Children?

Journal of Analytical Research in Clinical Medicine, 2017

Introduction: Attention deficit hyperactivity disorder (ADHD) is a chronic neurodevelopmental dis... more Introduction: Attention deficit hyperactivity disorder (ADHD) is a chronic neurodevelopmental disorder with high heritability. It is the most common childhood mental disorder. The key aspects of ADHD may put the affected children at risk for different traumatic experiences. Therefore, this study was conducted to investigate the relationship between the severity of trauma and ADHD symptoms in children. Methods: In this descriptive-correlational study, the target population included 90 children aged 6-12 years old, visiting Imam Reza, Children, Sina, and Shohada Hospitals in Tabriz, Iran. The severity of trauma was assessed, using placebo transdermal system (PTS), and the ADHD symptoms were evaluated, using Conners' Parent Rating Scale. To rule out other psychiatric disorders, the Child Symptoms Inventory-4 (CSI-4) was employed. Results: Results showed a significant positive correlation between the severity of trauma and ADHD, hyperactivity, oppositional/impulsivity, and attention-deficit scores (P < 0.01). In addition, results from the independent t-test suggested a significance difference between the ADHD and non-ADHD children in terms of the severity of trauma. Conclusion: There was a significant relationship between the symptoms of ADHD and the severity of trauma in children, in a way that the scores of the aforementioned variables improved with increasing the severity of trauma. Regarding the profound effects of trauma on human and financial resources, required measures should be taken for making house and school settings safe for such children.

Research paper thumbnail of Comparison of Open and Ultrasound-Guided Placement of Central Venous Catheter in Children Weighing Less Than Five Kilograms; A Randomized Clinical Trial

Academic Radiology, Jul 1, 2023

Research paper thumbnail of Study on Effectiveness of Barium Enema in the Diagnosis of Hirschsprung Disease

Research paper thumbnail of Twenty Years of Experience in Management of Intussusception: Saline Enema Reduction with Ultrasound Guidance

Çocuk cerrahisi dergisi, 2021

Research paper thumbnail of Splenogonadal Fusion, a Rare Benign Lesion of Testis

Medical journal of Tabriz University of Medical Sciences and Health Services, Dec 26, 2011

Research paper thumbnail of A Comparative Study of Single Scrotal Incision Orchiopexy of Children with Palpable Low-Lying Undescended Testis with Traditional Inguinal Method

Advances in pediatric surgery, 2019

Purpose: Undescended testis (UDT) is a developmental defect in which one or both testicles do not... more Purpose: Undescended testis (UDT) is a developmental defect in which one or both testicles do not arrive in the scrotum. Its prevalence at birth and one year after is 2%-4% and less than 1%, respectively. Currently, surgery is recommended to treat congenital cryptorchidism in order to prevent testicular degeneration. Classic method is performed via incision in inguinal and scrotum and the new method is done via incision in scrotum. Method: Sixty male participants with 65 UDT undergoing surgery were randomly assigned to scrotal incision (n=31) and classic inguinal incision methods (n=34). Patients were followed for 6 months and testicular atrophy, infection, recurrence, and duration of surgery were compared between two groups. Results: Scrotal incision compared to classic incision method had significantly lower duration of surgery (19.06±2.96 minutes vs. 30±10.42 minutes; p=0.002) and recurrence during follow-up (0 vs. 5 cases; p=0.026). There was only one surgical site infection in the scrotal incision method. There were hematoma and post-operative swelling in 13.3% of cases after scrotal incision method. Conclusion: Scrotal incision is an alternative method for the UDT with lower duration of surgery, lower recurrence rate, and better cosmetic results.

Research paper thumbnail of A Study on Diagnostic and Therapeutic Procedures in Infants and Children with Intussusception at Childern Hospital in Tabriz

Medical Journal of Tabriz University of Medical Sciences, 2004

Research paper thumbnail of Helicobacter Pylori and Infantile Hypertrophic Pyloric Stenosis

Medical journal of Tabriz University of Medical Sciences and Health Services, Apr 26, 2011

Background: Recently, it has been suggested that Helicobacter pylori might be a cause of some cas... more Background: Recently, it has been suggested that Helicobacter pylori might be a cause of some cases of infantile hypertrophic pyloric stenosis (IHPS) in infancy on the basis of its epidemiologic and clinical features. We performed this study to evaluate the possible relationship between IHPS and H. pylori. Design: In consecutive infants with IHPS, we performed upper gastrointestinal endoscopy with biopsy before pyloromyotomy. The endoscopic appearance of the pylorus was noted to validate endoscopic features of IHPS. Results: Sixteen infants, 15 male, 14 white, mean age 42 days, range 21 to 104 days, were studied. The index case had chronic active gastritis on biopsy with organisms suspicious for H. pylori. Four others had chronic active gastritis, six more had focal or mild chronic gastritis, five were normal, and none had H. pylori on histology or immune histochemical staining in selected cases. All patients had negative rapid urease test. Most common endoscopic findings of IHPS were thickened prominent asymmetric pyloric folds and pin-hole pylorus that could not be intubated by the pediatric endoscope. Conclusion: H. pylori was not specifically identified in our patients with IHPS. The presence of H. pylori-like organisms in the gastric mucosa in our index case and finding of chronic active gastritis in several others may indicate the possibility of an acquired infectious etiology for IHPS. JPGN 42:262Y264, 2006.

Research paper thumbnail of The relationship between attention-deficit/ hyperactivity disorder and trauma in adolescents

Journal of emergency practice and trauma, Jul 1, 2017

Introduction Attention-deficit/hyperactivity disorder (ADHD) is one of the most common disorders ... more Introduction Attention-deficit/hyperactivity disorder (ADHD) is one of the most common disorders which happens mostly at school years with symptoms like inattentiveness, hyperactivity, impulsive behaviors, or a combination of these symptoms (1). It may impair cognitive abilities and psycho-social functions. Not only it can have some effects on children and adolescents' life, but also it can affect the family's quality of life (2).The Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5) specifies this disorder based on two aspects of symptoms: 1) the aspect of attention deficiency and 2) hyperactivity and impulsiveness. Thus, it is necessary to control these symptoms in adolescents as they can cause some problems at school or in social places for them. Also, DSM5 introduces three subcategories (presentations) for ADHD: (a) inattentive, (b) hyperactive/impulsive and (c) combined (3). ADHD children may experience significant problems in adaptability because of their expected level of development or growth with their chronological age (4). In 60% of cases, symptoms rests until the adulthood stage and most cases are concomitant with other mental disorders such as depression, anxiety, obsession, learning disabilities, bipolar disorder, and so on (5-7). In some studies, the education failure and background emotional problems such as anxiety and depression were reported

Research paper thumbnail of Diagnostic Accuracy of Doppler Ultrasonography in Differentiation between Malignant and Benign Cervical Lymphadenopathies in Pediatric Age Group

Pakistan Journal of Biological Sciences, Jul 15, 2010

Cervical lymphadenopathy is a relatively common finding in pediatric age group and is caused by a... more Cervical lymphadenopathy is a relatively common finding in pediatric age group and is caused by a wide spectrum of diseases from transient infections to malignancies especially lymphomas. The present study was aimed at evaluating the diagnostic performance of grey-scale ultrasonography, color Doppler ultrasonography and power Doppler ultrasonography in differentiation of reactively and metastatically enlarged cervical lymph nodes in pediatric age group. Fifty children with cervical lymphadenopathies were assessed by ultrasonographic methods. In each patient, the longest (L) and transverse (T) diameters, L/T ratio and presence or absence of the normal hilar pattern were checked by grey-scale ultrasonography. Spectral parameters (resistive and pulsatility indices) and vascular distribution pattern of nodes were recorded by color and power Doppler ultrasonography, respectively. Following the ultrasonographic evaluations, biopsy and/or clinical follow up was applied for six months, based on the clinical and paraclinical findings. Statistical analyses were performed by chi-square test, independent t-test and receiver operator characteristic curves. The mean age of patients was 12.42 +/- 2.42 years. Twenty eight patients (56%) had malignant enlargement of lymph nodes. The mean value of L/T ratio in malignant group was 1.70 +/- 0.22 and 2.40 +/- 0.38 in non-malignant nodes (p &amp;amp;amp;amp;lt; 0.001). Sensitivity, specificity and accuracy of combined grey-scale and power Doppler ultrasonography were 70, 86 and 81%, respectively. Combination of grey-scale and power Doppler ultrasonography is recommended for the differentiation between the malignant and benign lymphadenopathies in children. Moreover, our findings revealed no diagnostic role of color Doppler ultrasonography in the selection of malignant cervical lymph nodes in children.

Research paper thumbnail of Reduction of Neonatal Gastroschisisa with or Without General Anesthesia

Medical journal of Tabriz University of Medical Sciences and Health Services, Sep 24, 2013

Backgrounds and Objectives: Gastroschisis is a congenital defect in anterior abdominal wall on ri... more Backgrounds and Objectives: Gastroschisis is a congenital defect in anterior abdominal wall on right side of umbilicus and abdominal viscera protrude from this defect. Reduction under general anesthesia is the routine method of treatment. Recently, to avoid complications of general anesthesia and intubation, reduction without anesthesia has been recommended. Materials and Methods: This study was conducted in Tabriz, Shahid Beheshti, Mashhad, Shiraz and Ghazvin medical universities between 2010 to 2012 all neonates with Gastroschisis were included and their parents were signed consent. Exclusion criteria were peritonitis, major anomalies and intestinal atresia. Then Gastroschisis was treated with or without general anesthesia. Results: Eighteen infants with Gastroschisis were enrolled the study. 8 cases treated without general anesthesia and 10 cases were reduced under general anesthesia. Infants in the second group had an increased duration of hospitalization, need for mechanical and prolonge, duration of TPN, need for subsequent surgical procedure and prolonge duration of stay in NICU, although it is not significant. Conclusion: Result of this study demonstrate whose patients was reduced without general anesthesia inward, have better outcomes to those whose bowel was reduced under general anesthesia and it seem inward reduction is a safe and effective method for treatment in this anomaly.

Research paper thumbnail of Diagnostic value of procalcitonin and apo-e in extrahepatic biliary atresia

PubMed, Oct 1, 2014

Objective: Extrahepatic biliary atresia (EHBA) is one of the main causes of neonatal cholestasis.... more Objective: Extrahepatic biliary atresia (EHBA) is one of the main causes of neonatal cholestasis. Its early diagnosis could increase the survival of the infants with early surgery. We evaluated the diagnostic accuracy of procalcitonin and apolipoprotein E (Apo-E) levels in infants with and without EHBA. Methods: This prospective study included 18 infants with EHBA and 15 infants with other causes of cholestasis. Blood samples were taken from each patient and different markers including procalcitonin and Apo-E levels were measured. ROC analysis was used to define sensitivity, specificity, positive and negative predictive value (PPV and NPV) for procalcitonin and Apo-E. Findings : There was a significantly positive correlation between Apo-E and SGOT (r=0.37, P=0.03), SGPT (r=0.38, P=0.02) and GGT (r=0.38, P=0.02), and an inverse correlation between procalcitonin and GGT (r=-0.45, P=0.01). Area under curve (AUC) for procalcitonin was 0.69 (P=0.05) with cut-point of 0.735 ng/ml. The sensitivity, specificity, PPV and NPV was 67%, 61%, 69% and 59%, respectively. AUC for Apo-E was 0.68 (P=0.06) for cut-point of 61.25 ng/ml with sensitivity, specificity, PPV and NPV of 67%, 67%, 71% and 67%, respectively. Conclusion: Both PCT and Apo-E have relatively good accuracy in diagnosing EHBA cases; we could not rely on these markers for diagnosis of EHBA, however, combinations of these biomarkers with other markers and imaging tests could improve their accuracy and may help to achieve a rapid and accurate diagnosis of EHBA.

Research paper thumbnail of Congenital diaphragmatic hernia: Prognostic value of hernia sac and size of defect

Journal of research in clinical medicine, Mar 12, 2022

Introduction: Congenital diaphragmatic hernia (CDH) is a congenital malformation with challenging... more Introduction: Congenital diaphragmatic hernia (CDH) is a congenital malformation with challenging management. The aim of this study was to evaluate the effect of the presence of hernia sac and defect size on the prognosis of CDH in Tabriz children's hospital. Methods: In this prospective study, all the infants with the diagnosis of CDH that were admitted to the Tabriz children's hospital since 2016-2019 were enrolled. The presence or absence of a hernia sac was evaluated, and the largest diameter on diaphragmatic defect was measured before the repair. Postoperative outcomes, including instability, duration of mechanical ventilation, mortality rate, or hospital discharge were obtained and analyzed. Results: Over the study period, 30 patients with CDH met the inclusion criteria, consisting of 15 males and 15 females. Fifteen cases were diagnosed during the first 24 hours of life and 16 cases experienced hypoxia in the first hour after birth. Defect size was significantly smaller in survived patients (P = 0.041). Postoperative death occurred in 9 (42.85%) patients without a hernia sac. Results showed that none of the cases with hernia sac expired (P = 0.035). Conclusion: In our study, the presence of the hernia sac was related to a lower postoperative mortality rate. Defect size in survived group was also smaller. It can be suggested that the presence of hernia sac and lower diameter of defect size act as good prognostic factors in the outcome of patients with CDH.