behzad lotfi | Tabriz University Of Medical Sciences (original) (raw)

Papers by behzad lotfi

Research paper thumbnail of Chronological perspective of substitute materials used for the surgical treatment of Peyronie’s disease: A scoping review of literature

Rivista Urologia, Nov 24, 2022

This comprehensive scoping review aimed to identify all up-to-date original publications relating... more This comprehensive scoping review aimed to identify all up-to-date original publications relating to substitute materials used for the surgical treatment of Peyronie’s disease (PD), and characterize what material in which chronological trends were published in the current literature. Using the PCC framework (P: population, C: concept, and C: context), a search strategy was developed and used in four electronic databases, in addition to the Google scholar. All current published, in-press, and pre-print manuscripts with available English full-text were included. Eligible studies were required to be original research articles of any study design, reporting the usage of grafts on surgical treatment of PD. Included studies were reported in a narrative synthesis format. A total of 3379 articles were identified via an electronic search of databases and a total of 171 articles entered this scoping review. Most studies originated from Europe ( n = 72) and North America ( n = 66). Reports from the other continents increase in number in the 21st century. Highest number of the published papers was seen in 2001 to 2005 pentad. Autologous grafts (53.5%). Allografts (22.7%) and xenografts (15.7%) were the most frequently reported materials. Time flow of the used material and the alterations in trends for them is quite considerable. A global perspective of relevant publications on substitute materials in the surgical management of PD is presented in this review. The information in this summary may assist in establishing future research priorities in this area.

Research paper thumbnail of The optimum cut-off value of contralateral testis size in the prediction of monorchidism in children with nonpalpable testis: A systematic review

Journal of Pediatric Urology

Research paper thumbnail of Safety and Efficacy of Anticholinergic and α-blocker Combination Therapy in Treatment of Benign Prostatic Hyperplasia

Research paper thumbnail of Protective effect of Eprosartan against ischemic acute renal injury: Acting on NF-κB, caspase 3, and Sirtuin 1

International Immunopharmacology

Research paper thumbnail of Case Report Disfiguring Abdominal Mass Due to a Huge Extraordinary Calyceal Diverticulum

Research paper thumbnail of S105 the Immediate Insertion of a Penile Prosthesis for Prolonged Ischemic Priapism

European Urology Supplements, 2010

the results of the surgery. 9 patients engaged in sexual intercourse regularly. All patients have... more the results of the surgery. 9 patients engaged in sexual intercourse regularly. All patients have maintained their penile length. conclusions: Prolonged ischemic priapism results in cavernosal fibrosis and a subsequent loss of penile length. The immediate insertion of a penile prosthesis in this situation is simple and maintains penile length. The complication rate is low and the subsequent outcome excellent.

Research paper thumbnail of Effects of extracorporeal shock wave lithotripsy on semen parameters in patients with lower ureteral stones

Journal of North Khorasan University of Medical Sciences, 2012

Research paper thumbnail of Urodynamic Findings in Young Women of Less Than Forty Years Old with Lower Urinary Tract Symptoms

Open Journal of Urology, 2012

Research paper thumbnail of Desmopressin as an Alternative Solution for Urinary Leakage After Ureterocaliceal Surgeries

Introduction: Persistent urine leakage is common following iatrogenic urinary collecting system i... more Introduction: Persistent urine leakage is common following iatrogenic urinary collecting system injuries. Management of a urine leak usually includes manipulations such as catheter drainage, ureteral stenting, and percutaneous nephrostomy placement. The aim of this study was investigation the potential beneficial effect of desmopressin in reduction of urinary leakage duration. Materials and Methods: Fifteen patients with incisional urinary leakage were enrolled in this study. They had undergone pyeloplasty (n = 9), pyelolithotomy (n = 4), and ureterocaliceal anastomosis (n = 1). All of them had ureteral stenting or nephrostomy catheters, and urinary leakage had lasted for at least 15 days. Seven patients received desmopressin spray, 1 puff, twice a day, from the 16th days of urinary leakage, and 8 patients (control group) did not receive any medical treatment. The duration of urinary leakage was compared between the two groups. Results: The patients were 5 women and 10 men with the median age of 37 years (range, 26 to 58 years). None of the patients had urinary obstruction. There were no significant differences in age and sex distribution between the two groups. The mean urinary leakage duration was 28.7 ± 7.2 days in the patients of desmopressin group and 47.7 ± 8.8 days in those of the control group (P = .04). Conclusion: Our study showed that desmopressin can reduce the duration of incisional urinary leakage. We conclude that patients with prolonged urinary leakage after pyelocaliceal surgery who does not respond to surgical urinary drainage may benefit from desmopressin.

Research paper thumbnail of Determining the degree of alignment of prostate carcinoma in a rectal biopsy with radical prostatectomy in patients with prostate carcinoma

Medical journal of Tabriz University of Medical Sciences and Health Services, 2021

Background: The purpose of this study was to determine the degree of alignment of prostate carcin... more Background: The purpose of this study was to determine the degree of alignment of prostate carcinoma in a rectal biopsy with radical prostatectomy in patients with prostate carcinoma to determine which biopsy samples are consistent with surgical specimens. Methods: In this cross-sectional study, out of 122 patients with prostate cancer who had undergone radical prostatectomy surgery in Sina hospital of Tabriz 65 patients with clinical records and pathological reports of needle biopsy, and radical prostatectomy biopsy specimens were available.The required information was recorded in questionnaire made for this study, and then the pathologic report and Gleason score and lymph-vascular involvement of the specimens were determined separately and finally the Trans rectal pathology report of the biopsy was compared with the histopathology report of radical prostatectomy in each patient. Results: The most common Gleason score and radical prostatectomy score were 6 (41.5%) and 6(40%), respe...

Research paper thumbnail of Bilateral Testicular Torsion: A Case Report

Case Reports in Clinical Practice

Bilateral testicular torsion is a rare condition. We report a case of a male newborn with bilater... more Bilateral testicular torsion is a rare condition. We report a case of a male newborn with bilateral enlarged and firm testes. Color-Doppler revealed no evidence of vascular flow in both testes. Although intraoperative findings were in favor of bilateral infarcted and gangrenous testes, the patient underwent bilateral orchiopexy after conferring with his parents. At sixmonth follow-up, both testicles were atrophic. Management of bilateral neonatal testicular torsion is controversial and includes conservative management, orchiopexy, and orchiectomy. The possibility of salvaging testis in neonatal testicular torsion is very low in each treatment modality.

Research paper thumbnail of Disfiguring abdominal mass due to a huge extraordinary calyceal diverticulum

Urology journal, 2010

The etiology of pyelocaliceal diverticulum is believed to be congenital.(2,4) Calyceal diverticul... more The etiology of pyelocaliceal diverticulum is believed to be congenital.(2,4) Calyceal diverticulum seen in the upper (70%), mid (12%), or lower (18%) calyx, arises frequently from the posterior aspect of the kidney and is usually unilateral. Although the typical calyceal cyst is smaller than 1 cm,(5) some larger ones are occasionally detected. Here, we report a huge extraordinary 18 × 16 cm calyceal diverticulum in a 19-year-old woman.

Research paper thumbnail of Characteristics of Traumatic Urogenital Injuries in Emergency Department; a 10-year Cross-sectional Study

Introduction: Urogenital system injuries (UGIs) are seen in 10% of adult cases with multiple trau... more Introduction: Urogenital system injuries (UGIs) are seen in 10% of adult cases with multiple trauma. Although UGIs are rarely life threatening, they can cause major long-term morbidities. This study aimed to evaluate the characteristics of traumatic UGIs in patients who were referred to emergency department following multiple traumas. Methods: This retrospective cross-sectional study was conducted on multiple trauma patients who were presented to emergency department during a 10-year period (2008-2017). All patients with kidney, ureter, bladder, urethra, or external genitalia injuries were studied. The patients’ data were extracted from their clinical profiles. Results: Out of the 13598 admitted patients in our trauma center, UGIs were seen in 267 (1.9%) cases. The mean age of patients with UGIs was 27.3 ± 6.1 years (74.15% male). The highest incidence of UGI was seen in those aged between 21 and 30 years (39.7%) and motorcycle accidents (49%) was the most frequent cause of trauma. ...

Research paper thumbnail of Effect of preoperative prostate volume on the improvement of lower urinary tract symptoms in patients with benign prostatic hyperplasia undergoing transurethral resection of prostate

Journal of Nephropathology, Dec 27, 2019

Benign prostate hyperplasia, pathophysiology contributes to bladder outlet obstruction due to fun... more Benign prostate hyperplasia, pathophysiology contributes to bladder outlet obstruction due to functional obstruction caused by gland size enlargement resulting in the lower urinary tract symptoms (LUTS). Objectives: To determine the correlation of the prostate volume with surgical outcomes and postoperative LUTS in patients with benign prostatic hyperplasia (BPH) undergoing transurethral resection of the prostate (TURP). Patients and Methods: Patients with BPH who were refractory for medical treatment enrolled in the study. Patients divided into three groups with attention to their prostate volume conducted by transabdominal ultrasonography. To evaluate patients' LUTS, the International Prostate Symptom Score (IPSS) questionnaire was filled for all patients preoperatively and during the first and third months follow up sessions. Results: In the current study, mean age of the patients was 66.92 ± 1.08 years. Of 111 patients, eight patients (7.2%) had prostate volume less than 30 cc, 59 patients (53.2%) had prostate volume between 30-60 cc, and 44 patients (39.6%) had prostate volume more than 60 cc. During first month postoperative, mean decrease in IPSS scores in patients with prostate volume less than 30 cc, prostate volume between 30-60 cc and prostate volume more than 30 cc were 27.72 ± 3.53, 27.32 ± 3.37 and 27.45 ± 2.87, respectively. The ANOVA test showed no significant difference between the groups (P= 0.93). Mean decrease in IPSS score during third month postoperative, had no significant difference between the three groups, too (P=0.71). Symptoms alleviation observed in 94.6% and 95.5% of the patients, during first and third months follow-up, respectively. Conclusion: There was no correlation between the IPSS scores decrease and patients' symptoms recovery and preoperative prostate volume in patients with BPH who underwent TRUP.

Research paper thumbnail of Renal and liver injury following the treatment of COVID-19 by remdesivir

Journal of Nephropathology

Remdesivir initially was intravenously administrated to treat the Ebola disease however right now... more Remdesivir initially was intravenously administrated to treat the Ebola disease however right now it has been administered to treat COVID-19 in some countries. However it is necessary to find the exact effect of remdesivir in patients with COVID-19. Remdesivir solution is administered with a cyclodextrin carrier that filters solely by the glomeruli; thereby patients with abnormal renal function cannot eliminate it quickly; therefore, remdesivir can lead to renal failure or liver dysfunction during therapeutic process of COVID-19. Assessment of renal function in patients with COVID-19 who have acute kidney injury (AKI) or end-stage renal disease is fundamental.

Research paper thumbnail of COVID-19 outbreak and the impact on renal disorders: A rapid review

Türk Üroloji Dergisi/Turkish Journal of Urology

Research paper thumbnail of Is Coronavirus Disease 2019 (COVID-19) Associated with Renal Involvement? A Review of Century Infection

Jundishapur Journal of Microbiology

Research paper thumbnail of Penile Strangulation by Hair: A Case Report

Case Reports in Clinical Practice

We present the diagnosis and surgical treatment of a boy with hair-thread penile strangulation. A... more We present the diagnosis and surgical treatment of a boy with hair-thread penile strangulation. A 9-year-old boy was admitted with chronic ulcer around the coronal sulcus of his penis due to hair wrap. The glans was approximately hanging from the penile shaft by a very slim pedicle. We anastomosed edges of transected corpus cavernosum and urethra and covered them by dartos flap and skin. Although glans of the penis was cyanotic in post-operative hospitalization days, the outcome of surgery was satisfying.

Research paper thumbnail of Impact of transcutaneous interferential electrical stimulation for management of primary bladder neck dysfunction in children

Journal of Pediatric Urology

Research paper thumbnail of Desmopressin as an alternative solution for urinary leakage after ureterocaliceal surgeries

Urology Journal, Feb 1, 2009

Persistent urine leakage is common following iatrogenic urinary collecting system injuries. Manag... more Persistent urine leakage is common following iatrogenic urinary collecting system injuries. Management of a urine leak usually includes manipulations such as catheter drainage, ureteral stenting, and percutaneous nephrostomy placement. The aim of this study was investigation the potential beneficial effect of desmopressin in reduction of urinary leakage duration. Fifteen patients with incisional urinary leakage were enrolled in this study. They had undergone pyeloplasty (n = 9), pyelolithotomy (n = 4), and ureterocaliceal anastomosis (n = 1). All of them had ureteral stenting or nephrostomy catheters, and urinary leakage had lasted for at least 15 days. Seven patients received desmopressin spray, 1 puff, twice a day, from the 16th days of urinary leakage, and 8 patients (control group) did not receive any medical treatment. The duration of urinary leakage was compared between the two groups. The patients were 5 women and 10 men with the median age of 37 years (range, 26 to 58 years). None of the patients had urinary obstruction. There were no significant differences in age and sex distribution between the two groups. The mean urinary leakage duration was 28.7 +/- 7.2 days in the patients of desmopressin group and 47.7 +/- 8.8 days in those of the control group (P = .04). Our study showed that desmopressin can reduce the duration of incisional urinary leakage. We conclude that patients with prolonged urinary leakage after pyelocaliceal surgery who does not respond to surgical urinary drainage may benefit from desmopressin.

Research paper thumbnail of Chronological perspective of substitute materials used for the surgical treatment of Peyronie’s disease: A scoping review of literature

Rivista Urologia, Nov 24, 2022

This comprehensive scoping review aimed to identify all up-to-date original publications relating... more This comprehensive scoping review aimed to identify all up-to-date original publications relating to substitute materials used for the surgical treatment of Peyronie’s disease (PD), and characterize what material in which chronological trends were published in the current literature. Using the PCC framework (P: population, C: concept, and C: context), a search strategy was developed and used in four electronic databases, in addition to the Google scholar. All current published, in-press, and pre-print manuscripts with available English full-text were included. Eligible studies were required to be original research articles of any study design, reporting the usage of grafts on surgical treatment of PD. Included studies were reported in a narrative synthesis format. A total of 3379 articles were identified via an electronic search of databases and a total of 171 articles entered this scoping review. Most studies originated from Europe ( n = 72) and North America ( n = 66). Reports from the other continents increase in number in the 21st century. Highest number of the published papers was seen in 2001 to 2005 pentad. Autologous grafts (53.5%). Allografts (22.7%) and xenografts (15.7%) were the most frequently reported materials. Time flow of the used material and the alterations in trends for them is quite considerable. A global perspective of relevant publications on substitute materials in the surgical management of PD is presented in this review. The information in this summary may assist in establishing future research priorities in this area.

Research paper thumbnail of The optimum cut-off value of contralateral testis size in the prediction of monorchidism in children with nonpalpable testis: A systematic review

Journal of Pediatric Urology

Research paper thumbnail of Safety and Efficacy of Anticholinergic and α-blocker Combination Therapy in Treatment of Benign Prostatic Hyperplasia

Research paper thumbnail of Protective effect of Eprosartan against ischemic acute renal injury: Acting on NF-κB, caspase 3, and Sirtuin 1

International Immunopharmacology

Research paper thumbnail of Case Report Disfiguring Abdominal Mass Due to a Huge Extraordinary Calyceal Diverticulum

Research paper thumbnail of S105 the Immediate Insertion of a Penile Prosthesis for Prolonged Ischemic Priapism

European Urology Supplements, 2010

the results of the surgery. 9 patients engaged in sexual intercourse regularly. All patients have... more the results of the surgery. 9 patients engaged in sexual intercourse regularly. All patients have maintained their penile length. conclusions: Prolonged ischemic priapism results in cavernosal fibrosis and a subsequent loss of penile length. The immediate insertion of a penile prosthesis in this situation is simple and maintains penile length. The complication rate is low and the subsequent outcome excellent.

Research paper thumbnail of Effects of extracorporeal shock wave lithotripsy on semen parameters in patients with lower ureteral stones

Journal of North Khorasan University of Medical Sciences, 2012

Research paper thumbnail of Urodynamic Findings in Young Women of Less Than Forty Years Old with Lower Urinary Tract Symptoms

Open Journal of Urology, 2012

Research paper thumbnail of Desmopressin as an Alternative Solution for Urinary Leakage After Ureterocaliceal Surgeries

Introduction: Persistent urine leakage is common following iatrogenic urinary collecting system i... more Introduction: Persistent urine leakage is common following iatrogenic urinary collecting system injuries. Management of a urine leak usually includes manipulations such as catheter drainage, ureteral stenting, and percutaneous nephrostomy placement. The aim of this study was investigation the potential beneficial effect of desmopressin in reduction of urinary leakage duration. Materials and Methods: Fifteen patients with incisional urinary leakage were enrolled in this study. They had undergone pyeloplasty (n = 9), pyelolithotomy (n = 4), and ureterocaliceal anastomosis (n = 1). All of them had ureteral stenting or nephrostomy catheters, and urinary leakage had lasted for at least 15 days. Seven patients received desmopressin spray, 1 puff, twice a day, from the 16th days of urinary leakage, and 8 patients (control group) did not receive any medical treatment. The duration of urinary leakage was compared between the two groups. Results: The patients were 5 women and 10 men with the median age of 37 years (range, 26 to 58 years). None of the patients had urinary obstruction. There were no significant differences in age and sex distribution between the two groups. The mean urinary leakage duration was 28.7 ± 7.2 days in the patients of desmopressin group and 47.7 ± 8.8 days in those of the control group (P = .04). Conclusion: Our study showed that desmopressin can reduce the duration of incisional urinary leakage. We conclude that patients with prolonged urinary leakage after pyelocaliceal surgery who does not respond to surgical urinary drainage may benefit from desmopressin.

Research paper thumbnail of Determining the degree of alignment of prostate carcinoma in a rectal biopsy with radical prostatectomy in patients with prostate carcinoma

Medical journal of Tabriz University of Medical Sciences and Health Services, 2021

Background: The purpose of this study was to determine the degree of alignment of prostate carcin... more Background: The purpose of this study was to determine the degree of alignment of prostate carcinoma in a rectal biopsy with radical prostatectomy in patients with prostate carcinoma to determine which biopsy samples are consistent with surgical specimens. Methods: In this cross-sectional study, out of 122 patients with prostate cancer who had undergone radical prostatectomy surgery in Sina hospital of Tabriz 65 patients with clinical records and pathological reports of needle biopsy, and radical prostatectomy biopsy specimens were available.The required information was recorded in questionnaire made for this study, and then the pathologic report and Gleason score and lymph-vascular involvement of the specimens were determined separately and finally the Trans rectal pathology report of the biopsy was compared with the histopathology report of radical prostatectomy in each patient. Results: The most common Gleason score and radical prostatectomy score were 6 (41.5%) and 6(40%), respe...

Research paper thumbnail of Bilateral Testicular Torsion: A Case Report

Case Reports in Clinical Practice

Bilateral testicular torsion is a rare condition. We report a case of a male newborn with bilater... more Bilateral testicular torsion is a rare condition. We report a case of a male newborn with bilateral enlarged and firm testes. Color-Doppler revealed no evidence of vascular flow in both testes. Although intraoperative findings were in favor of bilateral infarcted and gangrenous testes, the patient underwent bilateral orchiopexy after conferring with his parents. At sixmonth follow-up, both testicles were atrophic. Management of bilateral neonatal testicular torsion is controversial and includes conservative management, orchiopexy, and orchiectomy. The possibility of salvaging testis in neonatal testicular torsion is very low in each treatment modality.

Research paper thumbnail of Disfiguring abdominal mass due to a huge extraordinary calyceal diverticulum

Urology journal, 2010

The etiology of pyelocaliceal diverticulum is believed to be congenital.(2,4) Calyceal diverticul... more The etiology of pyelocaliceal diverticulum is believed to be congenital.(2,4) Calyceal diverticulum seen in the upper (70%), mid (12%), or lower (18%) calyx, arises frequently from the posterior aspect of the kidney and is usually unilateral. Although the typical calyceal cyst is smaller than 1 cm,(5) some larger ones are occasionally detected. Here, we report a huge extraordinary 18 × 16 cm calyceal diverticulum in a 19-year-old woman.

Research paper thumbnail of Characteristics of Traumatic Urogenital Injuries in Emergency Department; a 10-year Cross-sectional Study

Introduction: Urogenital system injuries (UGIs) are seen in 10% of adult cases with multiple trau... more Introduction: Urogenital system injuries (UGIs) are seen in 10% of adult cases with multiple trauma. Although UGIs are rarely life threatening, they can cause major long-term morbidities. This study aimed to evaluate the characteristics of traumatic UGIs in patients who were referred to emergency department following multiple traumas. Methods: This retrospective cross-sectional study was conducted on multiple trauma patients who were presented to emergency department during a 10-year period (2008-2017). All patients with kidney, ureter, bladder, urethra, or external genitalia injuries were studied. The patients’ data were extracted from their clinical profiles. Results: Out of the 13598 admitted patients in our trauma center, UGIs were seen in 267 (1.9%) cases. The mean age of patients with UGIs was 27.3 ± 6.1 years (74.15% male). The highest incidence of UGI was seen in those aged between 21 and 30 years (39.7%) and motorcycle accidents (49%) was the most frequent cause of trauma. ...

Research paper thumbnail of Effect of preoperative prostate volume on the improvement of lower urinary tract symptoms in patients with benign prostatic hyperplasia undergoing transurethral resection of prostate

Journal of Nephropathology, Dec 27, 2019

Benign prostate hyperplasia, pathophysiology contributes to bladder outlet obstruction due to fun... more Benign prostate hyperplasia, pathophysiology contributes to bladder outlet obstruction due to functional obstruction caused by gland size enlargement resulting in the lower urinary tract symptoms (LUTS). Objectives: To determine the correlation of the prostate volume with surgical outcomes and postoperative LUTS in patients with benign prostatic hyperplasia (BPH) undergoing transurethral resection of the prostate (TURP). Patients and Methods: Patients with BPH who were refractory for medical treatment enrolled in the study. Patients divided into three groups with attention to their prostate volume conducted by transabdominal ultrasonography. To evaluate patients' LUTS, the International Prostate Symptom Score (IPSS) questionnaire was filled for all patients preoperatively and during the first and third months follow up sessions. Results: In the current study, mean age of the patients was 66.92 ± 1.08 years. Of 111 patients, eight patients (7.2%) had prostate volume less than 30 cc, 59 patients (53.2%) had prostate volume between 30-60 cc, and 44 patients (39.6%) had prostate volume more than 60 cc. During first month postoperative, mean decrease in IPSS scores in patients with prostate volume less than 30 cc, prostate volume between 30-60 cc and prostate volume more than 30 cc were 27.72 ± 3.53, 27.32 ± 3.37 and 27.45 ± 2.87, respectively. The ANOVA test showed no significant difference between the groups (P= 0.93). Mean decrease in IPSS score during third month postoperative, had no significant difference between the three groups, too (P=0.71). Symptoms alleviation observed in 94.6% and 95.5% of the patients, during first and third months follow-up, respectively. Conclusion: There was no correlation between the IPSS scores decrease and patients' symptoms recovery and preoperative prostate volume in patients with BPH who underwent TRUP.

Research paper thumbnail of Renal and liver injury following the treatment of COVID-19 by remdesivir

Journal of Nephropathology

Remdesivir initially was intravenously administrated to treat the Ebola disease however right now... more Remdesivir initially was intravenously administrated to treat the Ebola disease however right now it has been administered to treat COVID-19 in some countries. However it is necessary to find the exact effect of remdesivir in patients with COVID-19. Remdesivir solution is administered with a cyclodextrin carrier that filters solely by the glomeruli; thereby patients with abnormal renal function cannot eliminate it quickly; therefore, remdesivir can lead to renal failure or liver dysfunction during therapeutic process of COVID-19. Assessment of renal function in patients with COVID-19 who have acute kidney injury (AKI) or end-stage renal disease is fundamental.

Research paper thumbnail of COVID-19 outbreak and the impact on renal disorders: A rapid review

Türk Üroloji Dergisi/Turkish Journal of Urology

Research paper thumbnail of Is Coronavirus Disease 2019 (COVID-19) Associated with Renal Involvement? A Review of Century Infection

Jundishapur Journal of Microbiology

Research paper thumbnail of Penile Strangulation by Hair: A Case Report

Case Reports in Clinical Practice

We present the diagnosis and surgical treatment of a boy with hair-thread penile strangulation. A... more We present the diagnosis and surgical treatment of a boy with hair-thread penile strangulation. A 9-year-old boy was admitted with chronic ulcer around the coronal sulcus of his penis due to hair wrap. The glans was approximately hanging from the penile shaft by a very slim pedicle. We anastomosed edges of transected corpus cavernosum and urethra and covered them by dartos flap and skin. Although glans of the penis was cyanotic in post-operative hospitalization days, the outcome of surgery was satisfying.

Research paper thumbnail of Impact of transcutaneous interferential electrical stimulation for management of primary bladder neck dysfunction in children

Journal of Pediatric Urology

Research paper thumbnail of Desmopressin as an alternative solution for urinary leakage after ureterocaliceal surgeries

Urology Journal, Feb 1, 2009

Persistent urine leakage is common following iatrogenic urinary collecting system injuries. Manag... more Persistent urine leakage is common following iatrogenic urinary collecting system injuries. Management of a urine leak usually includes manipulations such as catheter drainage, ureteral stenting, and percutaneous nephrostomy placement. The aim of this study was investigation the potential beneficial effect of desmopressin in reduction of urinary leakage duration. Fifteen patients with incisional urinary leakage were enrolled in this study. They had undergone pyeloplasty (n = 9), pyelolithotomy (n = 4), and ureterocaliceal anastomosis (n = 1). All of them had ureteral stenting or nephrostomy catheters, and urinary leakage had lasted for at least 15 days. Seven patients received desmopressin spray, 1 puff, twice a day, from the 16th days of urinary leakage, and 8 patients (control group) did not receive any medical treatment. The duration of urinary leakage was compared between the two groups. The patients were 5 women and 10 men with the median age of 37 years (range, 26 to 58 years). None of the patients had urinary obstruction. There were no significant differences in age and sex distribution between the two groups. The mean urinary leakage duration was 28.7 +/- 7.2 days in the patients of desmopressin group and 47.7 +/- 8.8 days in those of the control group (P = .04). Our study showed that desmopressin can reduce the duration of incisional urinary leakage. We conclude that patients with prolonged urinary leakage after pyelocaliceal surgery who does not respond to surgical urinary drainage may benefit from desmopressin.