Nathan Peled | Technion Israel Institute of Technology (original) (raw)

Papers by Nathan Peled

Research paper thumbnail of The Lumbar Lordosis in Males and Females, Revisited

Research paper thumbnail of The Role of Vertebral Morphometry in the Pathogenesis of Degenerative Lumbar Spinal Stenosis

BioMed Research International

The aim of the current study was to establish whether the vertebral morphometry (e.g., vertebral ... more The aim of the current study was to establish whether the vertebral morphometry (e.g., vertebral body width and spinal canal diameters) is associated with degenerative lumbar spinal stenosis (DLSS). A retrospective computerized tomography (CT) study from L1 to L5 for two sample populations was used. The first included 165 participants with symptomatic DLSS (sex ratio 80 M/85F), and the second had 180 individuals from the general population (sex ratio: 90 M/90F). Vertebral body length (VL) and width (VW) were significantly greater in the stenosis males and females compared to their counterparts in the control. The mean VL in the stenosis males was 31.3 mm at L1, 32.6 mm at L2, 34 mm at L3, 34.1 mm at L4, and 34.5 at L5 compared to 29.9 mm, 31.3 mm, 32.6 mm, 32.8 mm, and 32.9, respectively, in the control group ( P ≤ 0.003 ). Additionally, the bony anterior-posterior (AP) canal diameters and cross-sectional area (CSA) were significantly smaller in the stenosis group compared to the co...

Research paper thumbnail of A comparative shape analysis of the cervical spine between individuals with cervicogenic headaches and asymptomatic controls

Scientific Reports

As some researchers theorized that cervicogenic headache (CEH) might be related to bony and disca... more As some researchers theorized that cervicogenic headache (CEH) might be related to bony and discal features of the cervical spine, this retrospective study examined the shapes of the cervical vertebrae and intervertebral discs (IVDs) of individuals with CEH and compared them to asymptomatic controls. Scans of 40 subjects in their late 20’s–mid 30’s affected with CEH and 40 asymptomatic controls were obtained (overall = 19,040 measurements, age-sex matched, 20 males and 20 females in each group). The following cervical spine variables were measured: Supine lordosis, vertebral body-heights, A-P lengths, mediolateral widths and sagittal-wedging; IVDs heights and sagittal-wedging; pedicle heights, widths and transverse angles; laminar widths and transverse angles; articular facet angles, spinal canal, and transverse foramen lengths, widths, and areas. Both groups had similar shape variation along the cervical in all the measured parameters. There were no significant left–right differenc...

Research paper thumbnail of Spinous Process Inclination in Degenerative Lumbar Spinal Stenosis Individuals

BioMed Research International

The aim of this study is to determine the sagittal inclination of lumbar spinous processes (SPs) ... more The aim of this study is to determine the sagittal inclination of lumbar spinous processes (SPs) in individuals with degenerative lumbar spinal stenosis (DLSS). It is a retrospective computerized tomography (CT) study including 345 individuals divided into two groups: control (90 males, 90 females) and stenosis (80 males and 85 females. The SP inclination was measured in the midsagittal plane from L1 to L5 levels. Stenosis males (L3-L5) and females (L1, L4) manifested significantly greater SP inclination compared to their counterparts in the control group. Males had significantly horizontal SP orientation compared to females (L1, L2). We also found that SP inclination became steeper as we descend caudally. This study indicates that SP inclinations are significantly associated with DLSS.

Research paper thumbnail of Facet Tropism and Orientation: Risk Factors for Degenerative Lumbar Spinal Stenosis

BioMed Research International

The aim of this study is to establish whether facet tropism (FT) and orientation (FO) are associa... more The aim of this study is to establish whether facet tropism (FT) and orientation (FO) are associated with degenerative lumbar spinal stenosis (DLSS). A retrospective computerized tomography (CT) study including 274 individuals was divided into two groups: control (82 males and 81 females) and stenosis (59 males and 52 females). All participants have undergone high-resolution CT scan of the lumbar spine in the same position. FT and FO were measured at L1-2 to L5-S1. Significant sagittal FO was noted in the stenosis males (L2-3 to L4-5) and females (L2-3 to L5-S1) compared to the controls. The prevalence of FT was remarkably greater in the stenosis males (L4-5, L5-S1) and females (L3-4, L5-S1) compared to their counterparts in the control group. Our results also showed that FT (L3-4 to L5-S1) increases approximately 2.9 times the likelihood for DLSS development. This study indicates that FO and FT in the lower lumbar spine are significantly associated with DLSS.

Research paper thumbnail of Pedicle Morphometry Variations in Individuals with Degenerative Lumbar Spinal Stenosis

BioMed Research International

The aim of this study was to compare pedicle dimensions in degenerative lumbar spinal stenosis (D... more The aim of this study was to compare pedicle dimensions in degenerative lumbar spinal stenosis (DLSS) with those in the general population. A retrospective computerized tomography (CT) study for lumbar vertebrae (L1 to L5) from two sample populations was used. The first included 165 participants with symptomatic DLSS (age range: 40-88 years, sex ratio: 80 M/85 F), and the second had 180 individuals from the general population (age range: 40-99 years, sex ratio: 90 M/90 F). Both males and females in the stenosis group manifested significantly greater pedicle width than the control group at all lumbar levels (P<0.05). In addition, pedicle heights for stenosis females were remarkably smaller on L4 and L5 levels compared to their counterparts in the control group (P<0.001). Males have larger pedicles than females for all lumbar levels (P<0.001). Age and BMI did not demonstrate significant association with pedicle dimensions. Our outcomes indicate that individuals with DLSS have...

Research paper thumbnail of Is Lumbosacral Transitional Vertebra Associated with Degenerative Lumbar Spinal Stenosis?

BioMed Research International

The aim of this study was to shed light on the association between lumbosacral transitional verte... more The aim of this study was to shed light on the association between lumbosacral transitional vertebra (LSTV) and degenerative lumbar spinal stenosis (DLSS). A cross-sectional retrospective study was performed on 165 individuals that were diagnosed with clinical picture of DLSS (age range: 40-88 years; sex ratio: 80M/85F) and 180 individuals without DLSS related symptoms (age range: 40-99 years; sex ratio: 90M/90F). All participants had undergone high-resolution CT scan for the lumbar region in the same position. We also used the volume rendering method to obtain three-dimensional CT images of the lumbosacral area. Both males and females in the stenosis group manifest greater prevalence of LSTV than their counterparts in the control group (P<0.001). Furthermore, the presence of LSTV increases the likelihood of degenerative spinal stenosis (odds ratio= 3.741, P<0.001). In the control group, LSTV was more common in males, and sacral slope angle of males was significantly greater i...

Research paper thumbnail of Lumbar Schmorl’s Nodes and Their Correlation with Spine Configuration and Degeneration

BioMed Research International

The aim of this study was to reveal whether demographic aspect, vertebral morphometry, and spine ... more The aim of this study was to reveal whether demographic aspect, vertebral morphometry, and spine degeneration are associated with lumbar Schmorl’s nodes (SNs). A retrospective cross-sectional study was performed using data from the Department of Radiology (Carmel, Medical Center, Israel) for 180 individuals: age range between 40 and 99 years; 90 males and 90 females. All participants had undergone high-resolution CT scans for abdominal diagnostic purposes in the same supine position prior to our study, which enabled the processing of the scans in all planes and allowed a 3D reconstruction of the lower lumbar region. Eighty individuals (44.4%) had at least one SN along the lumbar spine, particularly at L3-4 level (30%). Vertebral body length (L1 to L3) and width (L1 and L4) were significantly greater in the SNs group compared to non-SNs group. On contrast, disc height (L3-4 and L4-5) was significantly lesser in SNs group than non-SNs group. SNs was significantly associated with smoki...

Research paper thumbnail of The earliest modern humans outside Africa

Science (New York, N.Y.), Jan 26, 2018

To date, the earliest modern human fossils found outside of Africa are dated to around 90,000 to ... more To date, the earliest modern human fossils found outside of Africa are dated to around 90,000 to 120,000 years ago at the Levantine sites of Skhul and Qafzeh. A maxilla and associated dentition recently discovered at Misliya Cave, Israel, was dated to 177,000 to 194,000 years ago, suggesting that members of the Homo sapiens clade left Africa earlier than previously thought. This finding changes our view on modern human dispersal and is consistent with recent genetic studies, which have posited the possibility of an earlier dispersal of Homo sapiens around 220,000 years ago. The Misliya maxilla is associated with full-fledged Levallois technology in the Levant, suggesting that the emergence of this technology is linked to the appearance of Homo sapiens in the region, as has been documented in Africa.

Research paper thumbnail of In the quest for degenerative lumbar spinal stenosis etiology: the Schmorl's nodes model

BMC musculoskeletal disorders, Apr 20, 2017

Degenerative lumbar spinal stenosis (DLSS) is a common health problem in the elderly and usually ... more Degenerative lumbar spinal stenosis (DLSS) is a common health problem in the elderly and usually associated with three-joint complex degeneration. Schmorl's nodes (SNs) are described as vertical herniation of the disc into the vertebral body through a weakened part of the end plate that can lead to disc degeneration. Since SNs can harm the spine unit stability, the association between DLSS and SNs is expected. The aim of this study is to shed light on the relationship between degenerative lumbar spinal stenosis and SNs. Two groups of individuals were studied: the first included 165 individuals with DLSS (age range: 40-88, sex ratio: 80 M/85 F) and the second 180 individuals without spinal stenosis related symptoms (age range: 40-99, sex ratio: 90 M/90 F). The presence or absence of SNs on the cranial and caudal end plate surfaces at the lumbosacral region (from L1 to S1 vertebra) was recorded, using CT images (Brilliance 64 Philips Medical System, Cleveland Ohio, thickness of th...

Research paper thumbnail of Sex estimation using computed tomography of the mandible

International journal of legal medicine, Jan 20, 2017

Sex estimation of skeletal parts is of great value even in the DNA era. When computed tomography ... more Sex estimation of skeletal parts is of great value even in the DNA era. When computed tomography (CT) facilities were introduced to forensic institutes, new possibilities for sex estimation emerged. The aim of this study was to develop a CT-based method for sex estimation using the mandible. Twenty-five CT-based measurements of the mandible were developed and carried out on 3D reconstructions (volume rendering) and cross sections of the lower jaw of 438 adult individuals (214 males and 224 females). Intraobserver and interobserver variances of the measurements were examined using intraclass correlation coefficient (ICC) analysis. Five discriminant functions were developed using different states of completeness of the mandible. The success rates of these equations were cross validated twice. The measurements were found to be highly reliable (for intraobserver 0.838 < ICC < 0.995 and for interobserver 0.71 < ICC < 0.996). For a complete mandible, the correct classification...

Research paper thumbnail of Hot Topic: CAD of Soft Carotid Plaques on CTA

Research paper thumbnail of Abstract 2234: Value of Multi-Detector Computed Tomography Evaluation of Myocardial Perfusion in the Assessment of Ischemic Heart Disease: Comparison with Nuclear Perfusion Imaging

Circulation, Oct 28, 2008

Research paper thumbnail of computed tomography Noninvasive evaluation of arterial grafts with newly released multidetector

Research paper thumbnail of Abstract 3684: Pulse Pressure - A Readily Available Independent Predictor of Extent of Coronary Artery Atheroma on 64 Slice Coronary CT Angiography in Asymptomatic Patients With Type 2 Diabetes Mellitus

Circulation, Oct 31, 2007

Research paper thumbnail of Visceral Fat Predicts Coronary Atherosclerosis Independently from the Metabolic Syndrome in Asymptomatic Diabetic Patients

Research paper thumbnail of Abstract 3824: Zero or Low Agatston Calcium Score Does Not Exclude Significant Coronary Stenosis in Symptomatic Patients Undergoing 64-Slice Cardiac Computed Tomography

Circulation, Oct 31, 2006

Research paper thumbnail of Abstract 3788: Framingham and UKPDS Risk Scores Predict Extent and Severity of Coronary Disease as Determined by 64 Slice Coronary CT Angiography in Asymptomatic Patients With Type 2 Diabetes Mellitus

Circulation, Oct 31, 2007

Research paper thumbnail of 40-slice 40スライスCTを使用したCardiovascular Imaging (先端技術講演会 3.0テスラMRIと40スライスCTの最新技術)

Research paper thumbnail of Assessment of the Risk of Perforation at CT Colonography

PURPOSE Recent studies have suggested that CT colonography and conventional colonoscopy have simi... more PURPOSE Recent studies have suggested that CT colonography and conventional colonoscopy have similar efficacy for detection of polyps >6 mm. However, procedural risks with emerging technology such as CT colonography need to be assessed to permit appropriate risk - benefit analysis . Our purpose was to assess the risk of perforation at CT colonography in a large cohort. METHOD AND MATERIALS Records of all CT colonography performed between January 2001 and April 2004 in 3 medical centers were retrieved. Information was obtained regarding colon perforation at CT colonography and outcome and management of these patients. The rates of colon perforation and subsequent surgery were calculated. RESULTS For 7,180 CT colonography studies, there were 3 cases of perforation, yielding an overall rate of perforation of 0.04% (0.03 - 0.05%; 95% confidence level). Two of these patients underwent surgery (1 in 3,590 studies). In both, perforation was at the level of the rectum and an anatomic obs...

Research paper thumbnail of The Lumbar Lordosis in Males and Females, Revisited

Research paper thumbnail of The Role of Vertebral Morphometry in the Pathogenesis of Degenerative Lumbar Spinal Stenosis

BioMed Research International

The aim of the current study was to establish whether the vertebral morphometry (e.g., vertebral ... more The aim of the current study was to establish whether the vertebral morphometry (e.g., vertebral body width and spinal canal diameters) is associated with degenerative lumbar spinal stenosis (DLSS). A retrospective computerized tomography (CT) study from L1 to L5 for two sample populations was used. The first included 165 participants with symptomatic DLSS (sex ratio 80 M/85F), and the second had 180 individuals from the general population (sex ratio: 90 M/90F). Vertebral body length (VL) and width (VW) were significantly greater in the stenosis males and females compared to their counterparts in the control. The mean VL in the stenosis males was 31.3 mm at L1, 32.6 mm at L2, 34 mm at L3, 34.1 mm at L4, and 34.5 at L5 compared to 29.9 mm, 31.3 mm, 32.6 mm, 32.8 mm, and 32.9, respectively, in the control group ( P ≤ 0.003 ). Additionally, the bony anterior-posterior (AP) canal diameters and cross-sectional area (CSA) were significantly smaller in the stenosis group compared to the co...

Research paper thumbnail of A comparative shape analysis of the cervical spine between individuals with cervicogenic headaches and asymptomatic controls

Scientific Reports

As some researchers theorized that cervicogenic headache (CEH) might be related to bony and disca... more As some researchers theorized that cervicogenic headache (CEH) might be related to bony and discal features of the cervical spine, this retrospective study examined the shapes of the cervical vertebrae and intervertebral discs (IVDs) of individuals with CEH and compared them to asymptomatic controls. Scans of 40 subjects in their late 20’s–mid 30’s affected with CEH and 40 asymptomatic controls were obtained (overall = 19,040 measurements, age-sex matched, 20 males and 20 females in each group). The following cervical spine variables were measured: Supine lordosis, vertebral body-heights, A-P lengths, mediolateral widths and sagittal-wedging; IVDs heights and sagittal-wedging; pedicle heights, widths and transverse angles; laminar widths and transverse angles; articular facet angles, spinal canal, and transverse foramen lengths, widths, and areas. Both groups had similar shape variation along the cervical in all the measured parameters. There were no significant left–right differenc...

Research paper thumbnail of Spinous Process Inclination in Degenerative Lumbar Spinal Stenosis Individuals

BioMed Research International

The aim of this study is to determine the sagittal inclination of lumbar spinous processes (SPs) ... more The aim of this study is to determine the sagittal inclination of lumbar spinous processes (SPs) in individuals with degenerative lumbar spinal stenosis (DLSS). It is a retrospective computerized tomography (CT) study including 345 individuals divided into two groups: control (90 males, 90 females) and stenosis (80 males and 85 females. The SP inclination was measured in the midsagittal plane from L1 to L5 levels. Stenosis males (L3-L5) and females (L1, L4) manifested significantly greater SP inclination compared to their counterparts in the control group. Males had significantly horizontal SP orientation compared to females (L1, L2). We also found that SP inclination became steeper as we descend caudally. This study indicates that SP inclinations are significantly associated with DLSS.

Research paper thumbnail of Facet Tropism and Orientation: Risk Factors for Degenerative Lumbar Spinal Stenosis

BioMed Research International

The aim of this study is to establish whether facet tropism (FT) and orientation (FO) are associa... more The aim of this study is to establish whether facet tropism (FT) and orientation (FO) are associated with degenerative lumbar spinal stenosis (DLSS). A retrospective computerized tomography (CT) study including 274 individuals was divided into two groups: control (82 males and 81 females) and stenosis (59 males and 52 females). All participants have undergone high-resolution CT scan of the lumbar spine in the same position. FT and FO were measured at L1-2 to L5-S1. Significant sagittal FO was noted in the stenosis males (L2-3 to L4-5) and females (L2-3 to L5-S1) compared to the controls. The prevalence of FT was remarkably greater in the stenosis males (L4-5, L5-S1) and females (L3-4, L5-S1) compared to their counterparts in the control group. Our results also showed that FT (L3-4 to L5-S1) increases approximately 2.9 times the likelihood for DLSS development. This study indicates that FO and FT in the lower lumbar spine are significantly associated with DLSS.

Research paper thumbnail of Pedicle Morphometry Variations in Individuals with Degenerative Lumbar Spinal Stenosis

BioMed Research International

The aim of this study was to compare pedicle dimensions in degenerative lumbar spinal stenosis (D... more The aim of this study was to compare pedicle dimensions in degenerative lumbar spinal stenosis (DLSS) with those in the general population. A retrospective computerized tomography (CT) study for lumbar vertebrae (L1 to L5) from two sample populations was used. The first included 165 participants with symptomatic DLSS (age range: 40-88 years, sex ratio: 80 M/85 F), and the second had 180 individuals from the general population (age range: 40-99 years, sex ratio: 90 M/90 F). Both males and females in the stenosis group manifested significantly greater pedicle width than the control group at all lumbar levels (P<0.05). In addition, pedicle heights for stenosis females were remarkably smaller on L4 and L5 levels compared to their counterparts in the control group (P<0.001). Males have larger pedicles than females for all lumbar levels (P<0.001). Age and BMI did not demonstrate significant association with pedicle dimensions. Our outcomes indicate that individuals with DLSS have...

Research paper thumbnail of Is Lumbosacral Transitional Vertebra Associated with Degenerative Lumbar Spinal Stenosis?

BioMed Research International

The aim of this study was to shed light on the association between lumbosacral transitional verte... more The aim of this study was to shed light on the association between lumbosacral transitional vertebra (LSTV) and degenerative lumbar spinal stenosis (DLSS). A cross-sectional retrospective study was performed on 165 individuals that were diagnosed with clinical picture of DLSS (age range: 40-88 years; sex ratio: 80M/85F) and 180 individuals without DLSS related symptoms (age range: 40-99 years; sex ratio: 90M/90F). All participants had undergone high-resolution CT scan for the lumbar region in the same position. We also used the volume rendering method to obtain three-dimensional CT images of the lumbosacral area. Both males and females in the stenosis group manifest greater prevalence of LSTV than their counterparts in the control group (P<0.001). Furthermore, the presence of LSTV increases the likelihood of degenerative spinal stenosis (odds ratio= 3.741, P<0.001). In the control group, LSTV was more common in males, and sacral slope angle of males was significantly greater i...

Research paper thumbnail of Lumbar Schmorl’s Nodes and Their Correlation with Spine Configuration and Degeneration

BioMed Research International

The aim of this study was to reveal whether demographic aspect, vertebral morphometry, and spine ... more The aim of this study was to reveal whether demographic aspect, vertebral morphometry, and spine degeneration are associated with lumbar Schmorl’s nodes (SNs). A retrospective cross-sectional study was performed using data from the Department of Radiology (Carmel, Medical Center, Israel) for 180 individuals: age range between 40 and 99 years; 90 males and 90 females. All participants had undergone high-resolution CT scans for abdominal diagnostic purposes in the same supine position prior to our study, which enabled the processing of the scans in all planes and allowed a 3D reconstruction of the lower lumbar region. Eighty individuals (44.4%) had at least one SN along the lumbar spine, particularly at L3-4 level (30%). Vertebral body length (L1 to L3) and width (L1 and L4) were significantly greater in the SNs group compared to non-SNs group. On contrast, disc height (L3-4 and L4-5) was significantly lesser in SNs group than non-SNs group. SNs was significantly associated with smoki...

Research paper thumbnail of The earliest modern humans outside Africa

Science (New York, N.Y.), Jan 26, 2018

To date, the earliest modern human fossils found outside of Africa are dated to around 90,000 to ... more To date, the earliest modern human fossils found outside of Africa are dated to around 90,000 to 120,000 years ago at the Levantine sites of Skhul and Qafzeh. A maxilla and associated dentition recently discovered at Misliya Cave, Israel, was dated to 177,000 to 194,000 years ago, suggesting that members of the Homo sapiens clade left Africa earlier than previously thought. This finding changes our view on modern human dispersal and is consistent with recent genetic studies, which have posited the possibility of an earlier dispersal of Homo sapiens around 220,000 years ago. The Misliya maxilla is associated with full-fledged Levallois technology in the Levant, suggesting that the emergence of this technology is linked to the appearance of Homo sapiens in the region, as has been documented in Africa.

Research paper thumbnail of In the quest for degenerative lumbar spinal stenosis etiology: the Schmorl's nodes model

BMC musculoskeletal disorders, Apr 20, 2017

Degenerative lumbar spinal stenosis (DLSS) is a common health problem in the elderly and usually ... more Degenerative lumbar spinal stenosis (DLSS) is a common health problem in the elderly and usually associated with three-joint complex degeneration. Schmorl's nodes (SNs) are described as vertical herniation of the disc into the vertebral body through a weakened part of the end plate that can lead to disc degeneration. Since SNs can harm the spine unit stability, the association between DLSS and SNs is expected. The aim of this study is to shed light on the relationship between degenerative lumbar spinal stenosis and SNs. Two groups of individuals were studied: the first included 165 individuals with DLSS (age range: 40-88, sex ratio: 80 M/85 F) and the second 180 individuals without spinal stenosis related symptoms (age range: 40-99, sex ratio: 90 M/90 F). The presence or absence of SNs on the cranial and caudal end plate surfaces at the lumbosacral region (from L1 to S1 vertebra) was recorded, using CT images (Brilliance 64 Philips Medical System, Cleveland Ohio, thickness of th...

Research paper thumbnail of Sex estimation using computed tomography of the mandible

International journal of legal medicine, Jan 20, 2017

Sex estimation of skeletal parts is of great value even in the DNA era. When computed tomography ... more Sex estimation of skeletal parts is of great value even in the DNA era. When computed tomography (CT) facilities were introduced to forensic institutes, new possibilities for sex estimation emerged. The aim of this study was to develop a CT-based method for sex estimation using the mandible. Twenty-five CT-based measurements of the mandible were developed and carried out on 3D reconstructions (volume rendering) and cross sections of the lower jaw of 438 adult individuals (214 males and 224 females). Intraobserver and interobserver variances of the measurements were examined using intraclass correlation coefficient (ICC) analysis. Five discriminant functions were developed using different states of completeness of the mandible. The success rates of these equations were cross validated twice. The measurements were found to be highly reliable (for intraobserver 0.838 < ICC < 0.995 and for interobserver 0.71 < ICC < 0.996). For a complete mandible, the correct classification...

Research paper thumbnail of Hot Topic: CAD of Soft Carotid Plaques on CTA

Research paper thumbnail of Abstract 2234: Value of Multi-Detector Computed Tomography Evaluation of Myocardial Perfusion in the Assessment of Ischemic Heart Disease: Comparison with Nuclear Perfusion Imaging

Circulation, Oct 28, 2008

Research paper thumbnail of computed tomography Noninvasive evaluation of arterial grafts with newly released multidetector

Research paper thumbnail of Abstract 3684: Pulse Pressure - A Readily Available Independent Predictor of Extent of Coronary Artery Atheroma on 64 Slice Coronary CT Angiography in Asymptomatic Patients With Type 2 Diabetes Mellitus

Circulation, Oct 31, 2007

Research paper thumbnail of Visceral Fat Predicts Coronary Atherosclerosis Independently from the Metabolic Syndrome in Asymptomatic Diabetic Patients

Research paper thumbnail of Abstract 3824: Zero or Low Agatston Calcium Score Does Not Exclude Significant Coronary Stenosis in Symptomatic Patients Undergoing 64-Slice Cardiac Computed Tomography

Circulation, Oct 31, 2006

Research paper thumbnail of Abstract 3788: Framingham and UKPDS Risk Scores Predict Extent and Severity of Coronary Disease as Determined by 64 Slice Coronary CT Angiography in Asymptomatic Patients With Type 2 Diabetes Mellitus

Circulation, Oct 31, 2007

Research paper thumbnail of 40-slice 40スライスCTを使用したCardiovascular Imaging (先端技術講演会 3.0テスラMRIと40スライスCTの最新技術)

Research paper thumbnail of Assessment of the Risk of Perforation at CT Colonography

PURPOSE Recent studies have suggested that CT colonography and conventional colonoscopy have simi... more PURPOSE Recent studies have suggested that CT colonography and conventional colonoscopy have similar efficacy for detection of polyps >6 mm. However, procedural risks with emerging technology such as CT colonography need to be assessed to permit appropriate risk - benefit analysis . Our purpose was to assess the risk of perforation at CT colonography in a large cohort. METHOD AND MATERIALS Records of all CT colonography performed between January 2001 and April 2004 in 3 medical centers were retrieved. Information was obtained regarding colon perforation at CT colonography and outcome and management of these patients. The rates of colon perforation and subsequent surgery were calculated. RESULTS For 7,180 CT colonography studies, there were 3 cases of perforation, yielding an overall rate of perforation of 0.04% (0.03 - 0.05%; 95% confidence level). Two of these patients underwent surgery (1 in 3,590 studies). In both, perforation was at the level of the rectum and an anatomic obs...