ahmad asghari | University of Tehran (original) (raw)

Papers by ahmad asghari

The present study investigate the effects of fresh onion juice on serum Urea, Uric acid and Creat... more The present study investigate the effects of fresh onion juice on serum Urea, Uric acid and Creatinine compared with zinc (Zn) sulfate in rats. A hundred and sixty-two male Wister rats randomly allocated into 9 treatment groups (each include 3 groups and 6 replicate). In group 1, animals drenched water. In group 2, 1cc fresh onion juice was offered. In group 3, rats were received 2cc fresh onion juice. Group 4 offered 15 mg/kg Zn sulfate complement. In group 5, 30 mg/kg Zn sulfate complement delivered to rats. In group 6, animals nourished with 1cc fresh onion juice + 15 mg/kg Zn sulfate complement. In group 7, n1cc fresh onion juice + 30 mg/kg zinc sulfate complement provided to rats. Group 8 consumed 2cc fresh onion juice + 15 mg/kg Zn sulfate complement. In group 9, animal gavage 2cc fresh onion juice + 30 mg/kg Zn sulfate. All animals had free access to chow pellet. Animals were kept 1

Journal of Animal and Veterinary Advances, Sep 1, 2012

In this study the effect of tryptophan amino acid on trichophyton verrucosum in normal and dermat... more In this study the effect of tryptophan amino acid on trichophyton verrucosum in normal and dermatophytic patients under in vivo and in vitro conditions were studied. From safe and suffering from dermatophytic people's blood sample was obtained and amounts of tryptophan amino acid in this people serums by HPLC method was measured and so mentioned fungi was cultured in cultures media with different concentrations of tryptophan. Each of samples repeated in 3 times and after 2 weeks the diameter of colonies was measured, the results of research statistically were analyzed by using the SAS software and comparison of mean by using the ANOVA was done. Result has shown that the diameter of colony in different concentration of tryptophan decreased in experimental fungi than control group. This appears that the tryptophan amino acid cause decrease in the trichophyton verrucosum growth. Thus, probably the mentioned amino acid has inhibitory effects on experimental fungi growth.

People who take onion (Allium sativum) supplements hope to improve their well-being and to reduce... more People who take onion (Allium sativum) supplements hope to improve their well-being and to reduce the risk of various diseases. Numerous myths about its medicinal properties have existed for centuries in various cultures. According to some investigators the lower incidence of widespread disease in southern countries may partly be due to consumption of large quantities of onion. The objective of this study was to determination of onion (Allium cepa. linn) extract on the serum concentration of cholesterol, triglycerides, LDL and HDL. In this experiment, 162 mature male rats (250 gm on the average) were acquired from Razi Serum-producing Institute of Karaj and transferred to keeping place and then divided into the 9 identical groups. In the present study, lipids of serum were significantly decreased consequent consumption of onion extract. In conclusion can be state that onion and zinc sulfate have the most important hypolipidemic effects that combined use of these elements showed best effect than alone use.

The present study investigate the effects of fresh onion juice on serum Urea, Uric acid and Creat... more The present study investigate the effects of fresh onion juice on serum Urea, Uric acid and Creatinine compared with zinc (Zn) sulfate in rats. A hundred and sixty-two male Wister rats randomly allocated into 9 treatment groups (each include 3 groups and 6 replicate). In group 1, animals drenched water. In group 2, 1cc fresh onion juice was offered. In group 3, rats were received 2cc fresh onion juice. Group 4 offered 15 mg/kg Zn sulfate complement. In group 5, 30 mg/kg Zn sulfate complement delivered to rats. In group 6, animals nourished with 1cc fresh onion juice + 15 mg/kg Zn sulfate complement. In group 7, n1cc fresh onion juice + 30 mg/kg zinc sulfate complement provided to rats. Group 8 consumed 2cc fresh onion juice + 15 mg/kg Zn sulfate complement. In group 9, animal gavage 2cc fresh onion juice + 30 mg/kg Zn sulfate. All animals had free access to chow pellet. Animals were kept 1 week for adaptation to experimental condition, and then received treatments for next 4 weeks. ...

The main porpoise of current research was to investigate effects of fresh onion juice on serum ma... more The main porpoise of current research was to investigate effects of fresh onion juice on serum magnesium (Mg) and iron (Fe) compared with zinc (Zn) sulfate in rats. A hundred and sixty-two male Wister rats randomly allocated into 9 treatment groups (each include 3 groups and 6 replicate). In group 1, animals drenched water. In group 2, 1cc fresh onion juice was offered. In group 3, rats were received 2cc fresh onion juice. Group 4 offered 15 mg/kg Zn sulfate complement. In group 5, 30 mg/kg Zn sulfate complement delivered to rats. In group 6, animals nourished with 1cc fresh onion juice + 15 mg/kg Zn sulfate complement. In group 7, n1cc fresh onion juice + 30 mg/kg zinc sulfate complement provided to rats. Group 8 consumed 2cc fresh onion juice + 15 mg/kg Zn sulfate complement. In group 9, animal gavage 2cc fresh onion juice + 30 mg/kg Zn sulfate. All animals had free access to chow pellet. Animals were kept 1 week for adaptation to experimental condition, and then received treatmen...

RSC Advances

In a reaction between cobalt (II) and ammonium oxalate in the presence of CTAB or F-127 as surfac... more In a reaction between cobalt (II) and ammonium oxalate in the presence of CTAB or F-127 as surfactant to control the particles size, the cobalt oxalate complex was formed. The precipitate was calcined and the resulted nano cobalt oxide was characterized by Fourier Transform Infrared spectroscopy (FTIR), Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM) and X-ray Diffraction (XRD) methods. The crystalline pure and nano-sized particles had an average size of less than 40 nm. Electrochemical properties were examined by cyclic voltammetry, galvanostatic charge/discharge and electrochemical impedance spectroscopy. A maximum specific capacitance of 351 F g −1 was obtained at a scan rate of 0.85 A g −1 in 2 M of KOH solution for Co 3 O 4 @Ni foam electrode (Co 3 O 4 @NF). Furthermore, the electrode exhibits excellent cycle life stability, and almost 98.6% of its initial specific capacitance was maintained after 1000 cycle tests.

RSC Adv., 2015

Application of surfactants in preparing nano cobalt oxide was effective in achieving a higher spe... more Application of surfactants in preparing nano cobalt oxide was effective in achieving a higher specific capacitance.

Electrochimica Acta

Present article introduces the electrochemical fabrication of cobalt oxide nanostructures on elec... more Present article introduces the electrochemical fabrication of cobalt oxide nanostructures on electroetched carbon fiber (ECF) by a cathodic potential step method. The morphology and composition of the nanostructures were studied by field emission scanning electron microscopy (FE-SEM), energy dispersive X-ray analysis (EDX), X-ray diffraction analysis (XRD) and thermal analysis (TA) methods. FE-SEM images confirm the formation of flower-like Co3O4 nanoflakes on ECF (Co3O4-ECF). Cobalt hydroxide nanostructures transform into spinel structure after annealing in air at 300 degrees C for 2 hours. The electrochemical and supercapacitive performance of Co3O4-ECF was investigated by cyclic voltammetry (CV), galvanostatic charge-discharge, and electrochemical impedance spectroscopy (EIS) in both three and two electrode systems in KOH solution. Results confirm the excellent supercapacitive behavior of nanostructured Co3O4-ECF with excellent cycling stability and capacitance retention. These c...

Materials Letters, 2015

ABSTRACT In this article, we report the electrochemical fabrication of cobalt hydroxide nanostruc... more ABSTRACT In this article, we report the electrochemical fabrication of cobalt hydroxide nanostructures on electro-etched-carbon fiber (Co(OH)2-ECF) by cathodic potential step method. Surface characterization studies were performed by scanning electron microscopy (SEM) and X-ray diffraction analysis (XRD). Electrochemical and capacitive behaviors of Co(OH)2-ECF were investigated using cyclic voltammetry and galvanostatic charge-discharge techniques in three and two-electrode systems. Our results confirmed the excellent supercapacitive behavior of Co(OH)2-ECF and reasonable cycling stability. These characteristics is originated from three dimensional structure of nanostructures which allows facile electrolyte transportation, in addition to the strong adhesion between Co(OH)2 and carbon fiber substrate. A specific capacitance of 1000 F g−1 at a current density of 3.1 A g−1 was obtained for Co(OH)2-ECF electrode.

Animal reproduction

The aim of the present study was to investigate effects of onion juice on semen values of malondi... more The aim of the present study was to investigate effects of onion juice on semen values of malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GPx) and total antioxidant status (TAS) compared to Zn sulfate in rats. One hundred and sixty-two Wistar male rats were randomly allocated into 9 treatment groups (each including 3 groups and 6 replicates). Group 1 served as control and received distilled water. In group 2, animals received 1 cc fresh onion juice. In group 3, rats were offered 2 cc fresh onion juice. Group 4 drenched 15 mg/kg zinc (Zn) sulfate. In group 5, rats were treated with 30 mg/kg Zn sulfate. Group 6 was offered 1cc fresh onion juice + 15 mg/kg Zn sulfate to experimental animals. In group 7, 1 cc fresh onion juice + 30 mg/kg Zn sulfate was provided to rats. Group 8 consumed 2 cc fresh onion juice + 15 mg/kg Zn sulfate. In group 9, animals provided 2 cc fresh onion juice + 30 mg/kg Zn sulfate. All groups were given treatments orally and ad libitum ...

Journal of Animal and Veterinary Advances, 2012

Journal of Animal and Veterinary Advances, 2012

Artificial Cells, Nanomedicine, and Biotechnology, 2016

Segmental bone loss due to trauma, infection, and tumor resection and even non-union results in t... more Segmental bone loss due to trauma, infection, and tumor resection and even non-union results in the vast demand for replacement and restoration of the function of the lost bone. The objective of this study is to utilize novel inorganic-organic nanocomposites for biomedical applications. Biodegradable implants have shown great promise for the repair of bone defects and have been commonly used as bone substitutes, which traditionally would be treated using metallic implants. In this study, 45 mature male New Zealand white rabbits 6-8 months and weighting 3-3.5 kg were examined. Rabbits were divided into three groups. Surgical procedures were done after an intramuscular injection of Ketamine 10% (ketamine hydrochloride, 50 mg/kg), Rompun 5% (xylazine, 5 mg/kg). Then an approximately 6 mm diameter -5 mm cylinder bone defect was created in the femur of one of the hind limbs. After inducing the surgical wound, all rabbits were colored and randomly divided into three experimental groups of nine animals each: Group 1 received medical pure nanocomposite polycaprolactone (PCL) granules, Group 2 received hydroxyapatite and Group 3 was a control group with no treatment. Histopathological evaluation was performed on days 15, 30 and 45 after surgery. On day 45 after surgery, the quantity of newly formed lamellar bone in the healing site in PCL group was better than onward compared with HA and control groups. Finally, nanocomposite PCL granules exhibited a reproducible bone-healing potential.

Lasers in Medical Science, 2016

The purpose of the present study was to assess the effects of low-level laser therapy (LLLT) on s... more The purpose of the present study was to assess the effects of low-level laser therapy (LLLT) on skeletal muscle ischemia-reperfusion (IR) injuries in streptozotocin-induced diabetic rats. Twenty male Wistar rats were randomly assigned into two experimental groups, as follows: the diabetic IR group (G1, n = 10) and the diabetic IR + LLLT group (G2, n = 10). Ischemia was induced in anesthetized rats from the right femoral artery clipping for 2 h, followed by a reperfusion for 24 h. Then, the laser irradiation (K30 handheld probe, AZOR, Technica, Russia, 650 nm, 30 mW, surface area = 1 cm(2), energy density = 1.8 J/cm(2)) was carried out by irradiating the rats over a unique point on the skin over the middle region of the right gastrocnemius muscle belly three times (every 8 h), starting after initiating the reperfusion for 3 min. At the end of the reperfusion period, rats were anaesthetized and blood samples were collected and used for the estimation of pO2, pCO2, pH, HCO3, serum creatine phosphokinase (CPK), and lactate dehydrogenase (LDH). Subsequently, the right gastrocnemius muscle samples were taken for wet/dry weight ratio assessment and histological/biochemical examination. The pO2, pCO2, HCO3, and pH levels were similar for both groups (P > 0.05). The serum LDH and CPK levels were significantly lower (P < 0.05) for G2 compared to G1. In comparison to G1, tissue malondialdehyde level in G2 was significantly decreased (P < 0.05). In G2, superoxide dismutase activity was significantly increased compared to G1 (P < 0.05). Unlike G2, a significant decrease in the activity of catalase was observed in G1 (P < 0.05). The wet/dry ratio in G1 was significantly higher than that of G2 (P < 0.05). Histological examination confirmed that the extent of muscle changes in G1 was higher than G2 (P < 0.05). Finally, according to this study, LLLT has a beneficial effect on the IR muscle injury treatment in the diabetic rats. Therefore, we suggest that further research needs to be conducted using different laser parameters and examining response over a longer period of tissue recovery.

Acta Cirurgica Brasileira, 2016

To investigate the protective effect of metformin on testicular ischemia/reperfusion (I/R) injury... more To investigate the protective effect of metformin on testicular ischemia/reperfusion (I/R) injury in rats.

Acta Cirurgica Brasileira, 2016

To evaluate the effect of Otostegia persica (O. persica) extract on renal damage induced by ische... more To evaluate the effect of Otostegia persica (O. persica) extract on renal damage induced by ischemia/reperfusion (I/R) in diabetic rats.

Journal of Environmental Biology, Mar 15, 2011

This study was done to evaluate the effect of propranolol hydrochloride and activated charcoal in... more This study was done to evaluate the effect of propranolol hydrochloride and activated charcoal in the treatment of Nerium oleander intoxication in sheep. Seven male native Iranian sheep (8-12 month) were randomly divided into two groups, 5 treatment and 2 controls. Sheep of both groups were administrated the lethal dose of 110 mg/kg body weight of dried oleander leaves. Animal in control group died within 41 to 56 hours after dosing of the plant. Clinical signs of toxicosis were developed within 60 minutes after dosing of the plant, such as distress, teeth grinding, anorexia, colic, vocalization, polyuria, moderate rumen distention, tachypnea and depression.

International Urology and Nephrology, 2016

The aim of this study was to assess the effects of naloxone, an opioid receptor antagonist, on th... more The aim of this study was to assess the effects of naloxone, an opioid receptor antagonist, on the renal injury as a remote organ after hepatic ischemia reperfusion (IR) in rats. Forty male Wistar rats were randomly allocated into four groups as follows: sham, sham + naloxone, IR and IR + naloxone. In anesthetized rats, hepatic ischemia was applied for 30 min in IR and IR + naloxone groups. Sham + naloxone and IR + naloxone groups were given naloxone (3.0 mg/kg, iv) 30 min before ischemia. After 24 h, blood and tissue samples were obtained for histopathological, tissue malondialdehyde (MDA) and biochemical analyses. Histopathological study of liver in IR group showed enlarged sinusoids, sinusoidal congestion, cellular degenerative changes and necrosis. The kidney of the rats with hepatic IR showed pathological changes in tubular cell swelling, tubular dilatation, moderate to severe necrosis, glomerular fibrosis and hemorrhage. Histological examination confirmed the extent of hepatic and renal changes in IR group was higher (P < 0.05) than in other groups. Rats that underwent hepatic IR exhibited significant increase in serum concentrations of urea and creatinine levels (P < 0.05). The serum alanine aminotransferase and aminotransferase values were significantly higher in IR group compared to the other groups (P < 0.05). Liver IR produced a significant increase in hepatic and renal tissue MDA levels, while pretreatment with naloxone was associated with a significantly lower MDA levels (P < 0.05). The results of this study showed that naloxone pretreatment protected the renal injury from hepatic IR.

ABSTRACT Peripheral nerve transections represent common clinical occurrence. There are two main r... more ABSTRACT Peripheral nerve transections represent common clinical occurrence. There are two main requirements for a good clinical outcome after these lesions. The first is surgical treatment so as to make possible the regeneration of the transected nerve fibers toward their original periphery. The second important requirement for successful recovery after a nerve lesion is postoperative rehabilitation treatment. In fact, although the surgical techniques have proved to lead almost always to the regeneration of nerve fibers, the degree of recovery can be highly variable among patients. The objective of this study was to investigate whether 780 nm low level lasers could stimulate the healing process in the sciatic nerve regeneration in rabbits submitted to complete transection through morphometric analysis. Twenty adult white New Zealand male rabbits were used, where the injury of the type neurotmesis of the right sciatic nerve under general anesthesia (intramuscular ketamine/xylazine and atropine sulfate) was approximated using prolene 6- 0. The rabbits were randomly distributed in 2 groups with 10 rabbits each. In group I, Arsenate of Gallium Laser was used with the extension of wave of 780 nm, 10 mW powers with 1 J/cm2 irradiation with 10 seconds for each Cm2, in the pulsed form. The laser therapy was initiated on the post-surgical first day with application 10 minutes for each rabbit in group I, once a day for 15 days. Rabbits in group II had not given treatment (control group). The samples of transected nerves were collected and prepared for morphometric analysis on the 90 days, they were analyzed the average number of total counted fibers and the mean fiber density on proximal, intermediate and distal segments. On group I and II, the average number of total counted fibers and the mean fiber density on proximal, intermediate and distal segments was significant in each group. The differences found for total number of counted fibers and for fibers density between proximal segments of groups I and II were not significant (p=0.31 and p=0.17, respectively). On intermediate segments (injury site), the total number of counted fibers was significantly higher in group I (p=0.05). On distal segments, both the total number and the density of fibers were significantly higher in group I (p=0.03 and 0.001, respectively). The irradiation with low level laser (780 nm) influenced positively the regeneration of the sciatic nerve in rabbits after being injured and end to end anastomosis, becoming the nerve recovery more rapid and efficient.

The present study investigate the effects of fresh onion juice on serum Urea, Uric acid and Creat... more The present study investigate the effects of fresh onion juice on serum Urea, Uric acid and Creatinine compared with zinc (Zn) sulfate in rats. A hundred and sixty-two male Wister rats randomly allocated into 9 treatment groups (each include 3 groups and 6 replicate). In group 1, animals drenched water. In group 2, 1cc fresh onion juice was offered. In group 3, rats were received 2cc fresh onion juice. Group 4 offered 15 mg/kg Zn sulfate complement. In group 5, 30 mg/kg Zn sulfate complement delivered to rats. In group 6, animals nourished with 1cc fresh onion juice + 15 mg/kg Zn sulfate complement. In group 7, n1cc fresh onion juice + 30 mg/kg zinc sulfate complement provided to rats. Group 8 consumed 2cc fresh onion juice + 15 mg/kg Zn sulfate complement. In group 9, animal gavage 2cc fresh onion juice + 30 mg/kg Zn sulfate. All animals had free access to chow pellet. Animals were kept 1

Journal of Animal and Veterinary Advances, Sep 1, 2012

In this study the effect of tryptophan amino acid on trichophyton verrucosum in normal and dermat... more In this study the effect of tryptophan amino acid on trichophyton verrucosum in normal and dermatophytic patients under in vivo and in vitro conditions were studied. From safe and suffering from dermatophytic people's blood sample was obtained and amounts of tryptophan amino acid in this people serums by HPLC method was measured and so mentioned fungi was cultured in cultures media with different concentrations of tryptophan. Each of samples repeated in 3 times and after 2 weeks the diameter of colonies was measured, the results of research statistically were analyzed by using the SAS software and comparison of mean by using the ANOVA was done. Result has shown that the diameter of colony in different concentration of tryptophan decreased in experimental fungi than control group. This appears that the tryptophan amino acid cause decrease in the trichophyton verrucosum growth. Thus, probably the mentioned amino acid has inhibitory effects on experimental fungi growth.

People who take onion (Allium sativum) supplements hope to improve their well-being and to reduce... more People who take onion (Allium sativum) supplements hope to improve their well-being and to reduce the risk of various diseases. Numerous myths about its medicinal properties have existed for centuries in various cultures. According to some investigators the lower incidence of widespread disease in southern countries may partly be due to consumption of large quantities of onion. The objective of this study was to determination of onion (Allium cepa. linn) extract on the serum concentration of cholesterol, triglycerides, LDL and HDL. In this experiment, 162 mature male rats (250 gm on the average) were acquired from Razi Serum-producing Institute of Karaj and transferred to keeping place and then divided into the 9 identical groups. In the present study, lipids of serum were significantly decreased consequent consumption of onion extract. In conclusion can be state that onion and zinc sulfate have the most important hypolipidemic effects that combined use of these elements showed best effect than alone use.

The present study investigate the effects of fresh onion juice on serum Urea, Uric acid and Creat... more The present study investigate the effects of fresh onion juice on serum Urea, Uric acid and Creatinine compared with zinc (Zn) sulfate in rats. A hundred and sixty-two male Wister rats randomly allocated into 9 treatment groups (each include 3 groups and 6 replicate). In group 1, animals drenched water. In group 2, 1cc fresh onion juice was offered. In group 3, rats were received 2cc fresh onion juice. Group 4 offered 15 mg/kg Zn sulfate complement. In group 5, 30 mg/kg Zn sulfate complement delivered to rats. In group 6, animals nourished with 1cc fresh onion juice + 15 mg/kg Zn sulfate complement. In group 7, n1cc fresh onion juice + 30 mg/kg zinc sulfate complement provided to rats. Group 8 consumed 2cc fresh onion juice + 15 mg/kg Zn sulfate complement. In group 9, animal gavage 2cc fresh onion juice + 30 mg/kg Zn sulfate. All animals had free access to chow pellet. Animals were kept 1 week for adaptation to experimental condition, and then received treatments for next 4 weeks. ...

The main porpoise of current research was to investigate effects of fresh onion juice on serum ma... more The main porpoise of current research was to investigate effects of fresh onion juice on serum magnesium (Mg) and iron (Fe) compared with zinc (Zn) sulfate in rats. A hundred and sixty-two male Wister rats randomly allocated into 9 treatment groups (each include 3 groups and 6 replicate). In group 1, animals drenched water. In group 2, 1cc fresh onion juice was offered. In group 3, rats were received 2cc fresh onion juice. Group 4 offered 15 mg/kg Zn sulfate complement. In group 5, 30 mg/kg Zn sulfate complement delivered to rats. In group 6, animals nourished with 1cc fresh onion juice + 15 mg/kg Zn sulfate complement. In group 7, n1cc fresh onion juice + 30 mg/kg zinc sulfate complement provided to rats. Group 8 consumed 2cc fresh onion juice + 15 mg/kg Zn sulfate complement. In group 9, animal gavage 2cc fresh onion juice + 30 mg/kg Zn sulfate. All animals had free access to chow pellet. Animals were kept 1 week for adaptation to experimental condition, and then received treatmen...

RSC Advances

In a reaction between cobalt (II) and ammonium oxalate in the presence of CTAB or F-127 as surfac... more In a reaction between cobalt (II) and ammonium oxalate in the presence of CTAB or F-127 as surfactant to control the particles size, the cobalt oxalate complex was formed. The precipitate was calcined and the resulted nano cobalt oxide was characterized by Fourier Transform Infrared spectroscopy (FTIR), Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM) and X-ray Diffraction (XRD) methods. The crystalline pure and nano-sized particles had an average size of less than 40 nm. Electrochemical properties were examined by cyclic voltammetry, galvanostatic charge/discharge and electrochemical impedance spectroscopy. A maximum specific capacitance of 351 F g −1 was obtained at a scan rate of 0.85 A g −1 in 2 M of KOH solution for Co 3 O 4 @Ni foam electrode (Co 3 O 4 @NF). Furthermore, the electrode exhibits excellent cycle life stability, and almost 98.6% of its initial specific capacitance was maintained after 1000 cycle tests.

RSC Adv., 2015

Application of surfactants in preparing nano cobalt oxide was effective in achieving a higher spe... more Application of surfactants in preparing nano cobalt oxide was effective in achieving a higher specific capacitance.

Electrochimica Acta

Present article introduces the electrochemical fabrication of cobalt oxide nanostructures on elec... more Present article introduces the electrochemical fabrication of cobalt oxide nanostructures on electroetched carbon fiber (ECF) by a cathodic potential step method. The morphology and composition of the nanostructures were studied by field emission scanning electron microscopy (FE-SEM), energy dispersive X-ray analysis (EDX), X-ray diffraction analysis (XRD) and thermal analysis (TA) methods. FE-SEM images confirm the formation of flower-like Co3O4 nanoflakes on ECF (Co3O4-ECF). Cobalt hydroxide nanostructures transform into spinel structure after annealing in air at 300 degrees C for 2 hours. The electrochemical and supercapacitive performance of Co3O4-ECF was investigated by cyclic voltammetry (CV), galvanostatic charge-discharge, and electrochemical impedance spectroscopy (EIS) in both three and two electrode systems in KOH solution. Results confirm the excellent supercapacitive behavior of nanostructured Co3O4-ECF with excellent cycling stability and capacitance retention. These c...

Materials Letters, 2015

ABSTRACT In this article, we report the electrochemical fabrication of cobalt hydroxide nanostruc... more ABSTRACT In this article, we report the electrochemical fabrication of cobalt hydroxide nanostructures on electro-etched-carbon fiber (Co(OH)2-ECF) by cathodic potential step method. Surface characterization studies were performed by scanning electron microscopy (SEM) and X-ray diffraction analysis (XRD). Electrochemical and capacitive behaviors of Co(OH)2-ECF were investigated using cyclic voltammetry and galvanostatic charge-discharge techniques in three and two-electrode systems. Our results confirmed the excellent supercapacitive behavior of Co(OH)2-ECF and reasonable cycling stability. These characteristics is originated from three dimensional structure of nanostructures which allows facile electrolyte transportation, in addition to the strong adhesion between Co(OH)2 and carbon fiber substrate. A specific capacitance of 1000 F g−1 at a current density of 3.1 A g−1 was obtained for Co(OH)2-ECF electrode.

Animal reproduction

The aim of the present study was to investigate effects of onion juice on semen values of malondi... more The aim of the present study was to investigate effects of onion juice on semen values of malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GPx) and total antioxidant status (TAS) compared to Zn sulfate in rats. One hundred and sixty-two Wistar male rats were randomly allocated into 9 treatment groups (each including 3 groups and 6 replicates). Group 1 served as control and received distilled water. In group 2, animals received 1 cc fresh onion juice. In group 3, rats were offered 2 cc fresh onion juice. Group 4 drenched 15 mg/kg zinc (Zn) sulfate. In group 5, rats were treated with 30 mg/kg Zn sulfate. Group 6 was offered 1cc fresh onion juice + 15 mg/kg Zn sulfate to experimental animals. In group 7, 1 cc fresh onion juice + 30 mg/kg Zn sulfate was provided to rats. Group 8 consumed 2 cc fresh onion juice + 15 mg/kg Zn sulfate. In group 9, animals provided 2 cc fresh onion juice + 30 mg/kg Zn sulfate. All groups were given treatments orally and ad libitum ...

Journal of Animal and Veterinary Advances, 2012

Journal of Animal and Veterinary Advances, 2012

Artificial Cells, Nanomedicine, and Biotechnology, 2016

Segmental bone loss due to trauma, infection, and tumor resection and even non-union results in t... more Segmental bone loss due to trauma, infection, and tumor resection and even non-union results in the vast demand for replacement and restoration of the function of the lost bone. The objective of this study is to utilize novel inorganic-organic nanocomposites for biomedical applications. Biodegradable implants have shown great promise for the repair of bone defects and have been commonly used as bone substitutes, which traditionally would be treated using metallic implants. In this study, 45 mature male New Zealand white rabbits 6-8 months and weighting 3-3.5 kg were examined. Rabbits were divided into three groups. Surgical procedures were done after an intramuscular injection of Ketamine 10% (ketamine hydrochloride, 50 mg/kg), Rompun 5% (xylazine, 5 mg/kg). Then an approximately 6 mm diameter -5 mm cylinder bone defect was created in the femur of one of the hind limbs. After inducing the surgical wound, all rabbits were colored and randomly divided into three experimental groups of nine animals each: Group 1 received medical pure nanocomposite polycaprolactone (PCL) granules, Group 2 received hydroxyapatite and Group 3 was a control group with no treatment. Histopathological evaluation was performed on days 15, 30 and 45 after surgery. On day 45 after surgery, the quantity of newly formed lamellar bone in the healing site in PCL group was better than onward compared with HA and control groups. Finally, nanocomposite PCL granules exhibited a reproducible bone-healing potential.

Lasers in Medical Science, 2016

The purpose of the present study was to assess the effects of low-level laser therapy (LLLT) on s... more The purpose of the present study was to assess the effects of low-level laser therapy (LLLT) on skeletal muscle ischemia-reperfusion (IR) injuries in streptozotocin-induced diabetic rats. Twenty male Wistar rats were randomly assigned into two experimental groups, as follows: the diabetic IR group (G1, n = 10) and the diabetic IR + LLLT group (G2, n = 10). Ischemia was induced in anesthetized rats from the right femoral artery clipping for 2 h, followed by a reperfusion for 24 h. Then, the laser irradiation (K30 handheld probe, AZOR, Technica, Russia, 650 nm, 30 mW, surface area = 1 cm(2), energy density = 1.8 J/cm(2)) was carried out by irradiating the rats over a unique point on the skin over the middle region of the right gastrocnemius muscle belly three times (every 8 h), starting after initiating the reperfusion for 3 min. At the end of the reperfusion period, rats were anaesthetized and blood samples were collected and used for the estimation of pO2, pCO2, pH, HCO3, serum creatine phosphokinase (CPK), and lactate dehydrogenase (LDH). Subsequently, the right gastrocnemius muscle samples were taken for wet/dry weight ratio assessment and histological/biochemical examination. The pO2, pCO2, HCO3, and pH levels were similar for both groups (P > 0.05). The serum LDH and CPK levels were significantly lower (P < 0.05) for G2 compared to G1. In comparison to G1, tissue malondialdehyde level in G2 was significantly decreased (P < 0.05). In G2, superoxide dismutase activity was significantly increased compared to G1 (P < 0.05). Unlike G2, a significant decrease in the activity of catalase was observed in G1 (P < 0.05). The wet/dry ratio in G1 was significantly higher than that of G2 (P < 0.05). Histological examination confirmed that the extent of muscle changes in G1 was higher than G2 (P < 0.05). Finally, according to this study, LLLT has a beneficial effect on the IR muscle injury treatment in the diabetic rats. Therefore, we suggest that further research needs to be conducted using different laser parameters and examining response over a longer period of tissue recovery.

Acta Cirurgica Brasileira, 2016

To investigate the protective effect of metformin on testicular ischemia/reperfusion (I/R) injury... more To investigate the protective effect of metformin on testicular ischemia/reperfusion (I/R) injury in rats.

Acta Cirurgica Brasileira, 2016

To evaluate the effect of Otostegia persica (O. persica) extract on renal damage induced by ische... more To evaluate the effect of Otostegia persica (O. persica) extract on renal damage induced by ischemia/reperfusion (I/R) in diabetic rats.

Journal of Environmental Biology, Mar 15, 2011

This study was done to evaluate the effect of propranolol hydrochloride and activated charcoal in... more This study was done to evaluate the effect of propranolol hydrochloride and activated charcoal in the treatment of Nerium oleander intoxication in sheep. Seven male native Iranian sheep (8-12 month) were randomly divided into two groups, 5 treatment and 2 controls. Sheep of both groups were administrated the lethal dose of 110 mg/kg body weight of dried oleander leaves. Animal in control group died within 41 to 56 hours after dosing of the plant. Clinical signs of toxicosis were developed within 60 minutes after dosing of the plant, such as distress, teeth grinding, anorexia, colic, vocalization, polyuria, moderate rumen distention, tachypnea and depression.

International Urology and Nephrology, 2016

The aim of this study was to assess the effects of naloxone, an opioid receptor antagonist, on th... more The aim of this study was to assess the effects of naloxone, an opioid receptor antagonist, on the renal injury as a remote organ after hepatic ischemia reperfusion (IR) in rats. Forty male Wistar rats were randomly allocated into four groups as follows: sham, sham + naloxone, IR and IR + naloxone. In anesthetized rats, hepatic ischemia was applied for 30 min in IR and IR + naloxone groups. Sham + naloxone and IR + naloxone groups were given naloxone (3.0 mg/kg, iv) 30 min before ischemia. After 24 h, blood and tissue samples were obtained for histopathological, tissue malondialdehyde (MDA) and biochemical analyses. Histopathological study of liver in IR group showed enlarged sinusoids, sinusoidal congestion, cellular degenerative changes and necrosis. The kidney of the rats with hepatic IR showed pathological changes in tubular cell swelling, tubular dilatation, moderate to severe necrosis, glomerular fibrosis and hemorrhage. Histological examination confirmed the extent of hepatic and renal changes in IR group was higher (P < 0.05) than in other groups. Rats that underwent hepatic IR exhibited significant increase in serum concentrations of urea and creatinine levels (P < 0.05). The serum alanine aminotransferase and aminotransferase values were significantly higher in IR group compared to the other groups (P < 0.05). Liver IR produced a significant increase in hepatic and renal tissue MDA levels, while pretreatment with naloxone was associated with a significantly lower MDA levels (P < 0.05). The results of this study showed that naloxone pretreatment protected the renal injury from hepatic IR.

ABSTRACT Peripheral nerve transections represent common clinical occurrence. There are two main r... more ABSTRACT Peripheral nerve transections represent common clinical occurrence. There are two main requirements for a good clinical outcome after these lesions. The first is surgical treatment so as to make possible the regeneration of the transected nerve fibers toward their original periphery. The second important requirement for successful recovery after a nerve lesion is postoperative rehabilitation treatment. In fact, although the surgical techniques have proved to lead almost always to the regeneration of nerve fibers, the degree of recovery can be highly variable among patients. The objective of this study was to investigate whether 780 nm low level lasers could stimulate the healing process in the sciatic nerve regeneration in rabbits submitted to complete transection through morphometric analysis. Twenty adult white New Zealand male rabbits were used, where the injury of the type neurotmesis of the right sciatic nerve under general anesthesia (intramuscular ketamine/xylazine and atropine sulfate) was approximated using prolene 6- 0. The rabbits were randomly distributed in 2 groups with 10 rabbits each. In group I, Arsenate of Gallium Laser was used with the extension of wave of 780 nm, 10 mW powers with 1 J/cm2 irradiation with 10 seconds for each Cm2, in the pulsed form. The laser therapy was initiated on the post-surgical first day with application 10 minutes for each rabbit in group I, once a day for 15 days. Rabbits in group II had not given treatment (control group). The samples of transected nerves were collected and prepared for morphometric analysis on the 90 days, they were analyzed the average number of total counted fibers and the mean fiber density on proximal, intermediate and distal segments. On group I and II, the average number of total counted fibers and the mean fiber density on proximal, intermediate and distal segments was significant in each group. The differences found for total number of counted fibers and for fibers density between proximal segments of groups I and II were not significant (p=0.31 and p=0.17, respectively). On intermediate segments (injury site), the total number of counted fibers was significantly higher in group I (p=0.05). On distal segments, both the total number and the density of fibers were significantly higher in group I (p=0.03 and 0.001, respectively). The irradiation with low level laser (780 nm) influenced positively the regeneration of the sciatic nerve in rabbits after being injured and end to end anastomosis, becoming the nerve recovery more rapid and efficient.