Yoshiaki Kikuchi | Tokyo Metropolitan University (original) (raw)
Papers by Yoshiaki Kikuchi
PubMed, 2021
In our previous study, the brain activity of areas related to social dominance [dorsomedial prefr... more In our previous study, the brain activity of areas related to social dominance [dorsomedial prefrontal cortex (DMPFC)] and reward [ventral striatum (VS)] was compared before and after providing information (cue) indicating that an applied cream was luxury. Both the DMPFC and VS showed significantly higher activation after this cue, and the cue also facilitated the connection between the DMPFC and VS via the dorsolateral prefrontal cortex (DLPFC). Therefore, it may likewise have an effect on primary (SI) and secondary (SII) somatosensory areas. In the current study, we explored this hypothesis by performing correlation analyses of the same data and found a significant positive correlation between the VS and the right SII during the application of the cream even before the cue, and significant correlations between the VS and the right SI, SII, and DLPFC after. These results suggest that the emotional value based on texture is mainly processed through the connection between the SII and VS, and luxury cues further facilitate the connection between the VS and the SI, which plays a role in discriminating the physical aspects of creams. Therefore, we provide neuroscientific evidence of the synergistic effect of luxury cues on pleasant tactile and social dominance feelings.
Transactions of the Japanese society for artificial intelligence, 2001
<p>This shows how the brain regions, showing significantly higher activity in females than ... more <p>This shows how the brain regions, showing significantly higher activity in females than males in the present study, may have interrelationships with each other, based on the causality proposed by the somatic marker model <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037901#pone.0037901-VerdejoGarcia1" target="_blank">[73]</a>. The results on causality were not obtained in the present study. (1) Even incongruent associations (i.e., self = negative) have been firmly stored in the hippocampus and vmPFC as self-schema (surrounded with a green dot line). This information automatically acts as a secondary inducer in the face of threats (green solid line), (2) vmPFC triggers emotional (somatic) states and awareness of bodily feelings (postcentral/IPL) when the inducer is activated (blue solid lines), and (3) such somatic states influence the neural processes for emotional responses and emotion control where dACC plays an important role (red solid line). Each brain region surrounded with a solid black line is that showed significantly higher activity in females than males, in the present study, and “brainstem” and “somatic states”, each of which is surrounded with a dot black line and connected with a red dot line and a blue one, are shown based on the somatic marker model <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037901#pone.0037901-VerdejoGarcia1" target="_blank">[73]</a>.</p
Transactions of the Japanese society for artificial intelligence, 2001
Emotional Engineering, Vol. 8, 2020
Attachment security is a critical resource for individuals to preserve relationship quality. Inse... more Attachment security is a critical resource for individuals to preserve relationship quality. Insecure attachment reduces relationship quality and can seriously influence mental and physical health. Adult attachment style is thought to develop through relationships with a caregiver during childhood and social interactions during adolescence according to epigenetic modification and reinforcement learning mechanisms, and is an important factor for developing and maintaining relationship quality. The neurochemicals such as oxytocin (OXT), dopamine (DA), and serotonin (5-HT) have been shown to be critical for pair-bond formation and maintenance by animal experiments. However, the neural basis underlying the human adult attachment has not yet been clarified. We investigated whether the brain regions involved in these neurochemicals are correlated with adult attachment style in healthy male participants using functional magnetic resonance imaging (fMRI). Significantly activated brain regions, while they were viewing their partner compared to unknown females included the hypothalamus, substantia nigra/ventral tegmental area (SN/VTA), dorsal raphe nucleus (DRN) and locus coeruleus (LC), in which each of these regions is involved in OXT, DA, 5-HT and norepinephrine, respectively. Moreover, higher activity in these brainstem regions was associated with less attachment anxiety. These brainstem regions are primarily important for basic survival functions and well-being. Based on these results, in humans, neurochemicals such as OXT, DA, and 5-HT may be also critical for developing and maintaining relationships, and adult attachment style may be developed based on the epigenetic modification and reinforcement learning mechanisms through relationships with a caregiver during childhood.
We used functional magnetic resonance imaging to investigate the similarities in the attachment t... more We used functional magnetic resonance imaging to investigate the similarities in the attachment toward individual's favorite cosmetics and beloved person, both of which are reinforced by touch-driven behaviors. We conducted 2 (visual and visual with tactile) × 2 (preferred and non-preferred cosmetics) experiments. Thereafter, we set regions of interest as per previous studies of human relationship attachment and tested their significance. The hippocampus, posterior cingulate cortex (PCC), putamen, periaqueductal gray (PAG), dorsal raphe nucleus (DRN), and ventral tegmental area were activated in the visual with tactile session, but not in the visual session, revealing that common brain regions are activated in human relationship attachment and attachment to cosmetics, and that tactile cue is important for attachment to cosmetics. Moreover, the PAG showed an interactive effect between tactile cue and preference, and the DRN positively correlated with "security" feeling ...
Scientific Reports, 2021
The neurobiological basis of brand and product attachment has received much attention in consumer... more The neurobiological basis of brand and product attachment has received much attention in consumer neuroscience research, although it remains unclear. In this study, we conducted functional MRI experiments involving female users of famous luxury brand cosmetics as participants, based on the regions of interest involved in human attachment and object attachment. The results showed that the left ventral pallidum (VP), which is involved in positive reward, and the right posterior cingulate cortex (PCC), which is involved in self-concept, a key concept in object attachment, are the core regions in cosmetic attachment. Moreover, the performed psychophysiological interaction analyses showed that VP-temporoparietal junction connectivity positively correlated with activity in the dorsal raphe nucleus, and PCC–anterior hippocampus (aHC) connectivity positively correlated with subjective evaluation of attachment. The former suggests that object attachment is a human-like attachment and a stron...
People sometimes experience an emotional state known as ‘nostalgia’, which involves experiencing ... more People sometimes experience an emotional state known as ‘nostalgia’, which involves experiencing predominantly positive emotions while remembering autobiographical events. Nostalgia is thought to play an important role in psychological resilience. Here, we examined the brain activity and subjective feelings associated with nostalgic experiences, using childhood-related visual stimuli. We confirmed the presence of nostalgia-related activity in both memory and reward systems, including the hippocampus (HC), substantia nigra/ventral tegmental area (SN/VTA), and ventral striatum (VS). We also found significant HC-VS co-activation, with its strength correlating with individual nostalgia tendencies. Factor analyses showed that two dimensions underlie nostalgia: emotional and personal significance and chronological remoteness, with the former correlating with caudal SN/VTA and left anterior HC activity, and the latter correlating with rostral SN/VTA activity. These findings demonstrate the...
Our behavioral response to our own crisis situations activates an automatic neural mechanism for ... more Our behavioral response to our own crisis situations activates an automatic neural mechanism for protecting ourselves, while our response to others’ crisis situations is not always toward saving them. That is, this automatic neural mechanism is implemented in our brain essentially for protecting not others, but the self, based on a biological principle. In this regard, it can be said that we have a type of Selfish Brain mechanism, which works primarily for protecting the self. Here, we focused on bodily unstable situations, and investigated whether the Selfish Brain could be observed or not, by viewing these bodily unstable situations of the self and others, and comparing the neural and behavioral responses, based on a third-person perspective paradigm. We found significant brain activity specific to one’s own bodily crisis, but no significant activity in others’ crisis situations. These self-specific regions included the regions that would be activated during genuine unstable bodil...
Self-touch is an act of coping with harmful or stressful situations based on suppression of somat... more Self-touch is an act of coping with harmful or stressful situations based on suppression of somatosensory perception, somatosensory cortex activity, and sympathetic activity; however, the detailed neural mechanism remains unknown. Several studies have shown that the descending pain modulatory system (DPMS) plays critical roles in painful situations and that intrinsic functional connectivity in the DPMS is observed in even non-painful situations. Therefore, we hypothesized that the neural system consisting of the anterior cingulate cortex, amygdala, and rostral ventromedial medulla (RVM) would play a basic role in self-touch. We thus investigated the interactive effects of these regions in a pain-free self-touch situation. Functional magnetic resonance imaging was used to investigate brain activity induced by mere self-touch (rubbing the left hand with the right), and the physio-physiological interaction analysis was performed to investigate the modulatory effects of brain activity. ...
Recent advances in functional brain imaging enable identification of active areas of a brain perf... more Recent advances in functional brain imaging enable identification of active areas of a brain performing a certain function. Induction of logical formulas describing relations between brain areas and brain functions from functional brain images is a category of data mining. It is difficult, however, to apply conventional mining techniques to functional brain images due to several reasons, such as the difficulty of reducing images to symbolic data, possible existence of correlations between adjacent pixels in a image and the limited number of samples available from a single subject. Tsukimoto and Morita presented an algorithm for data mining from functional brain images and showed that the algorithm works well for artificial data. The algorithm consists of two steps. The first step is nonparametric regression. The second step is rule extraction from the linear formula obtained by the nonparametric regression. The authors have applied the algorithm to real f-MRI images. This paper repo...
The Journal of Physical Fitness and Sports Medicine, 2015
PubMed, 2021
In our previous study, the brain activity of areas related to social dominance [dorsomedial prefr... more In our previous study, the brain activity of areas related to social dominance [dorsomedial prefrontal cortex (DMPFC)] and reward [ventral striatum (VS)] was compared before and after providing information (cue) indicating that an applied cream was luxury. Both the DMPFC and VS showed significantly higher activation after this cue, and the cue also facilitated the connection between the DMPFC and VS via the dorsolateral prefrontal cortex (DLPFC). Therefore, it may likewise have an effect on primary (SI) and secondary (SII) somatosensory areas. In the current study, we explored this hypothesis by performing correlation analyses of the same data and found a significant positive correlation between the VS and the right SII during the application of the cream even before the cue, and significant correlations between the VS and the right SI, SII, and DLPFC after. These results suggest that the emotional value based on texture is mainly processed through the connection between the SII and VS, and luxury cues further facilitate the connection between the VS and the SI, which plays a role in discriminating the physical aspects of creams. Therefore, we provide neuroscientific evidence of the synergistic effect of luxury cues on pleasant tactile and social dominance feelings.
Transactions of the Japanese society for artificial intelligence, 2001
<p>This shows how the brain regions, showing significantly higher activity in females than ... more <p>This shows how the brain regions, showing significantly higher activity in females than males in the present study, may have interrelationships with each other, based on the causality proposed by the somatic marker model <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037901#pone.0037901-VerdejoGarcia1" target="_blank">[73]</a>. The results on causality were not obtained in the present study. (1) Even incongruent associations (i.e., self = negative) have been firmly stored in the hippocampus and vmPFC as self-schema (surrounded with a green dot line). This information automatically acts as a secondary inducer in the face of threats (green solid line), (2) vmPFC triggers emotional (somatic) states and awareness of bodily feelings (postcentral/IPL) when the inducer is activated (blue solid lines), and (3) such somatic states influence the neural processes for emotional responses and emotion control where dACC plays an important role (red solid line). Each brain region surrounded with a solid black line is that showed significantly higher activity in females than males, in the present study, and “brainstem” and “somatic states”, each of which is surrounded with a dot black line and connected with a red dot line and a blue one, are shown based on the somatic marker model <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037901#pone.0037901-VerdejoGarcia1" target="_blank">[73]</a>.</p
Transactions of the Japanese society for artificial intelligence, 2001
Emotional Engineering, Vol. 8, 2020
Attachment security is a critical resource for individuals to preserve relationship quality. Inse... more Attachment security is a critical resource for individuals to preserve relationship quality. Insecure attachment reduces relationship quality and can seriously influence mental and physical health. Adult attachment style is thought to develop through relationships with a caregiver during childhood and social interactions during adolescence according to epigenetic modification and reinforcement learning mechanisms, and is an important factor for developing and maintaining relationship quality. The neurochemicals such as oxytocin (OXT), dopamine (DA), and serotonin (5-HT) have been shown to be critical for pair-bond formation and maintenance by animal experiments. However, the neural basis underlying the human adult attachment has not yet been clarified. We investigated whether the brain regions involved in these neurochemicals are correlated with adult attachment style in healthy male participants using functional magnetic resonance imaging (fMRI). Significantly activated brain regions, while they were viewing their partner compared to unknown females included the hypothalamus, substantia nigra/ventral tegmental area (SN/VTA), dorsal raphe nucleus (DRN) and locus coeruleus (LC), in which each of these regions is involved in OXT, DA, 5-HT and norepinephrine, respectively. Moreover, higher activity in these brainstem regions was associated with less attachment anxiety. These brainstem regions are primarily important for basic survival functions and well-being. Based on these results, in humans, neurochemicals such as OXT, DA, and 5-HT may be also critical for developing and maintaining relationships, and adult attachment style may be developed based on the epigenetic modification and reinforcement learning mechanisms through relationships with a caregiver during childhood.
We used functional magnetic resonance imaging to investigate the similarities in the attachment t... more We used functional magnetic resonance imaging to investigate the similarities in the attachment toward individual's favorite cosmetics and beloved person, both of which are reinforced by touch-driven behaviors. We conducted 2 (visual and visual with tactile) × 2 (preferred and non-preferred cosmetics) experiments. Thereafter, we set regions of interest as per previous studies of human relationship attachment and tested their significance. The hippocampus, posterior cingulate cortex (PCC), putamen, periaqueductal gray (PAG), dorsal raphe nucleus (DRN), and ventral tegmental area were activated in the visual with tactile session, but not in the visual session, revealing that common brain regions are activated in human relationship attachment and attachment to cosmetics, and that tactile cue is important for attachment to cosmetics. Moreover, the PAG showed an interactive effect between tactile cue and preference, and the DRN positively correlated with "security" feeling ...
Scientific Reports, 2021
The neurobiological basis of brand and product attachment has received much attention in consumer... more The neurobiological basis of brand and product attachment has received much attention in consumer neuroscience research, although it remains unclear. In this study, we conducted functional MRI experiments involving female users of famous luxury brand cosmetics as participants, based on the regions of interest involved in human attachment and object attachment. The results showed that the left ventral pallidum (VP), which is involved in positive reward, and the right posterior cingulate cortex (PCC), which is involved in self-concept, a key concept in object attachment, are the core regions in cosmetic attachment. Moreover, the performed psychophysiological interaction analyses showed that VP-temporoparietal junction connectivity positively correlated with activity in the dorsal raphe nucleus, and PCC–anterior hippocampus (aHC) connectivity positively correlated with subjective evaluation of attachment. The former suggests that object attachment is a human-like attachment and a stron...
People sometimes experience an emotional state known as ‘nostalgia’, which involves experiencing ... more People sometimes experience an emotional state known as ‘nostalgia’, which involves experiencing predominantly positive emotions while remembering autobiographical events. Nostalgia is thought to play an important role in psychological resilience. Here, we examined the brain activity and subjective feelings associated with nostalgic experiences, using childhood-related visual stimuli. We confirmed the presence of nostalgia-related activity in both memory and reward systems, including the hippocampus (HC), substantia nigra/ventral tegmental area (SN/VTA), and ventral striatum (VS). We also found significant HC-VS co-activation, with its strength correlating with individual nostalgia tendencies. Factor analyses showed that two dimensions underlie nostalgia: emotional and personal significance and chronological remoteness, with the former correlating with caudal SN/VTA and left anterior HC activity, and the latter correlating with rostral SN/VTA activity. These findings demonstrate the...
Our behavioral response to our own crisis situations activates an automatic neural mechanism for ... more Our behavioral response to our own crisis situations activates an automatic neural mechanism for protecting ourselves, while our response to others’ crisis situations is not always toward saving them. That is, this automatic neural mechanism is implemented in our brain essentially for protecting not others, but the self, based on a biological principle. In this regard, it can be said that we have a type of Selfish Brain mechanism, which works primarily for protecting the self. Here, we focused on bodily unstable situations, and investigated whether the Selfish Brain could be observed or not, by viewing these bodily unstable situations of the self and others, and comparing the neural and behavioral responses, based on a third-person perspective paradigm. We found significant brain activity specific to one’s own bodily crisis, but no significant activity in others’ crisis situations. These self-specific regions included the regions that would be activated during genuine unstable bodil...
Self-touch is an act of coping with harmful or stressful situations based on suppression of somat... more Self-touch is an act of coping with harmful or stressful situations based on suppression of somatosensory perception, somatosensory cortex activity, and sympathetic activity; however, the detailed neural mechanism remains unknown. Several studies have shown that the descending pain modulatory system (DPMS) plays critical roles in painful situations and that intrinsic functional connectivity in the DPMS is observed in even non-painful situations. Therefore, we hypothesized that the neural system consisting of the anterior cingulate cortex, amygdala, and rostral ventromedial medulla (RVM) would play a basic role in self-touch. We thus investigated the interactive effects of these regions in a pain-free self-touch situation. Functional magnetic resonance imaging was used to investigate brain activity induced by mere self-touch (rubbing the left hand with the right), and the physio-physiological interaction analysis was performed to investigate the modulatory effects of brain activity. ...
Recent advances in functional brain imaging enable identification of active areas of a brain perf... more Recent advances in functional brain imaging enable identification of active areas of a brain performing a certain function. Induction of logical formulas describing relations between brain areas and brain functions from functional brain images is a category of data mining. It is difficult, however, to apply conventional mining techniques to functional brain images due to several reasons, such as the difficulty of reducing images to symbolic data, possible existence of correlations between adjacent pixels in a image and the limited number of samples available from a single subject. Tsukimoto and Morita presented an algorithm for data mining from functional brain images and showed that the algorithm works well for artificial data. The algorithm consists of two steps. The first step is nonparametric regression. The second step is rule extraction from the linear formula obtained by the nonparametric regression. The authors have applied the algorithm to real f-MRI images. This paper repo...
The Journal of Physical Fitness and Sports Medicine, 2015