Mahdi Najafi | Tehran University of Medical Sciences (original) (raw)

Papers by Mahdi Najafi

Research paper thumbnail of SORT maneuver for nasogastric tube insertion

Research paper thumbnail of Prevention of tooth and gum damage: an oft neglected advantage of indirect laryngoscopy with Airtraq

Research paper thumbnail of Relationship between serum magnesium level and post coronary artery bypass graft surgery arrhythmias: A-757

European Journal of Anaesthesiology, 2006

Introduction: Atrial and ventricular arrhythmias are among the most common complications after co... more Introduction: Atrial and ventricular arrhythmias are among the most common complications after coronary artery bypass graft (CABG) surgery. It is known that cardiopulmonary bypass reduces serum magnesium level. In this study, we evaluated the relationship between total blood magnesium level (TMG) and the incidence of perioperative arrhythmias.

Research paper thumbnail of Updates on Coagulation Management in Cardiac Surgery

Journal of Tehran University Heart Center, Jul 1, 2014

This paper should be cited as: Najafi M, Faraoni D. Updates on Coagulation Management in Cardiac ... more This paper should be cited as: Najafi M, Faraoni D. Updates on Coagulation Management in Cardiac Surgery. J Teh Univ Heart Ctr 2014;9(3):99-103.

Research paper thumbnail of Interactive web-based lifestyle intervention and metabolic syndrome: findings from the Red Ruby (a randomized controlled trial)

Trials, 2015

Background: Metabolic syndrome is a growing public health problem worldwide. Several intervention... more Background: Metabolic syndrome is a growing public health problem worldwide. Several interventions have been proposed to specifically target the problem. This study evaluated the effectiveness of an interactive web-based lifestyle for management of metabolic syndrome. Methods: This randomized controlled trial was conducted from June through August 2012 in Tehran, Iran. Participants were individuals with metabolic syndrome who had registered on the study website. Interested eligible participants were invited for a free clinic visit and clinical assessment. They were randomly assigned to the intervention (n = 80) or control (n = 80) group. The intervention group received an interactive web-based program called the Healthy Heart Profile and were followed for 6 months. The control group received general information on metabolic syndrome. Anthropometric measures, glycemic status, and lipid profile were evaluated at baseline, and at 3-and 6-month follow-up assessments. Metabolic syndrome was defined according to The National Cholesterol Education Program Adult Treatment Panel (ATP) III report except for waist circumference, which was modified to ≥90 cm for both genders for the Iranian population.

Research paper thumbnail of Under- and overreporting of energy in a group of candidates for CABG surgery and its association with some anthropometric and sociodemographic factors, Tehran, Iran

Vascular Health and Risk Management

Numerous studies have documented a high prevalence of misreporting energy intakes. This paper exa... more Numerous studies have documented a high prevalence of misreporting energy intakes. This paper examines the prevalence of under- and overreporting of energy intake in a group of candidates for coronary artery bypass graft (CABG) surgery and its association with body mass index (BMI) and some sociodemographic factors. Dietary assessment (using a food frequency questionnaire) and demographic evaluation of 449 CABG surgery candidates was performed. Weight and height was also measured. McCrory equation was used to identify inaccurate records of energy intake. With this equation, reporting energy intake less than 78% and more than 122% of predicted energy expenditure was considered as under- and overreporting, respectively. Less than half of the participants reported energy intakes within the plausible limits. There were more overreporters than underreporters in this sample. The only significant association between misreporting and related factors was seen in BMI groups. As BMI increased,...

Research paper thumbnail of Construct, Validity and Reliability of Anesthesiology Problem Score Questionnaire

Research paper thumbnail of Quantitative measurement and ranking of occupational stressors: a preliminary study in anesthesiology residents

Research paper thumbnail of Fast-track method in cardiac surgery: Evaluation of risks and benefits of continuous administration technique

Singapore medical journal

Introduction: Fast-track is a method proposed to decrease medical costs through the reduction of ... more Introduction: Fast-track is a method proposed to decrease medical costs through the reduction of patients' length of stay in the hospital. This study was carried out to assess the risks and benefits of conducting the fast-track method in cardiac anaesthesia and to evaluate the role of continuous infusion of short-acting anaesthetics in a successful fast-track protocol. Methods: 100 cases were divided into two groups. In the fast-track group, fentanyl and propofol infusions were started at induction time and atracurium one hour later. No bolus drug was administered during the operation. Fentanyl infusion was continued up to 12 hours after surgery. The conventional extubation group received fentanyl and pancuronium as bolus doses. The two groups were evaluated for time of alertness and extubation in the intensive care unit, total analgesic dosage administered during the 24 hours after operation, arterial blood gas and peripheral saturation of oxygen before and after extubation. Re...

Research paper thumbnail of Relationship between serum magnesium level and post coronary artery bypass graft surgery arrhythmias

European Journal of Anaesthesiology

Introduction: Atrial and ventricular arrhythmias are among the most common complications after co... more Introduction: Atrial and ventricular arrhythmias are among the most common complications after coronary artery bypass graft (CABG) surgery. It is known that cardiopulmonary bypass reduces serum magnesium level. In this study, we evaluated the relationship between total blood magnesium level (TMG) and the incidence of perioperative arrhythmias.

Research paper thumbnail of Discriminative Power of EuroSCORE in Predicting Morbidity and Prolonged Hospital Stay in an Iranian Sample Population

Journal of Tehran University Heart Center

The EuroSCORE is a simple and rigorous risk stratification model and is, thus, commonly used in p... more The EuroSCORE is a simple and rigorous risk stratification model and is, thus, commonly used in predicting the early and late outcomes of cardiac surgery across the world. We aimed to assess the discriminative power of the EuroSCORE model to predict postoperative morbidity and total prolonged length of stay in hospital (LOS) and Intensive Care Unit (ICU) stay in an Iranian group of cardiac surgical population. In a prospective study, the additive EuroSCORE model was applied to 570 patients undergoing isolated coronary artery bypass grafting (CABG) at Tehran Heart Center. The discrimination power of the EuroSCORE model was tested by the area under the receiver operating characteristic (ROC) curve and the calibration by comparing the observed and predicted outcomes across the risk spectrum assessed using the Hosmer-Lemeshow goodness-of-fit test. The mean age was 59.03 ± 0.73 years and 429 out of the 570 (75.3%) patients were men. The overall morbidity rate was 47.5%. The observed morb...

Research paper thumbnail of Can a New Antiseptic Agent Reduce the Bacterial Colonization Rate of Central Venous Lines in PostCardiac Surgery Patients?

Journal of Tehran University Heart Center

Background: Central venous (CV) catheters play an essential role in the management of critically ... more Background: Central venous (CV) catheters play an essential role in the management of critically ill patients in the Intensive Care Unit (ICU). CV lines are, however, allied to catheter-associated blood stream infections. Bacterial colonization of CV lines is deemed the main cause of catheter-associated infection. The purpose of our study was to compare bacterial colony counts in the catheter site before CV line insertion in two groups of post-cardiac surgery patients: a group receiving Sanosil (an antiseptic agent composed of H2O2 and silver) and a control group. Methods: This interventional prospective double-blinded clinical trial recruited the patients in three post-cardiac surgery ICUs of a heart center. The participants were divided into interventional (113 patients) and control (136 patients) groups. Sanosil was added to the routine preparation procedure (Chlorhexidine bath one day before and scrub with Povidone-Iodine just before the CV line insertion). After the removal of ...

Research paper thumbnail of Do the metabolic syndrome associated with impaired Health Related Quality Of Life among People with Metabolic Syndrome ? A web-Based Study

Research paper thumbnail of Do preoperative pulmonary function indices predict morbidity after coronary artery bypass surgery?

Annals of Cardiac Anaesthesia, 2015

The reported prevalence of chronic obstructive pulmonary disease (COPD) varies among different gr... more The reported prevalence of chronic obstructive pulmonary disease (COPD) varies among different groups of cardiac surgical patients. Moreover, the prognostic value of preoperative COPD in outcome prediction is controversial. Aims: The present study assessed the morbidity in the different levels of COPD severity and the role of pulmonary function indices in predicting morbidity in patients undergoing coronary artery bypass graft (CABG). Settings and Design: Patients who were candidates for isolated CABG with cardiopulmonary bypass who were recruited for Tehran Heart Center-Coronary Outcome Measurement Study. Methods: Based on spirometry findings, diagnosis of COPD was considered based on Global Initiative for Chronic Obstructive Lung Disease category as forced expiratory volume in 1 s [FEV1]/forced vital capacity <0.7 (absolute value, not the percentage of the predicted). Society of Thoracic Surgeons (STS) definition was used for determining COPD severity and the patients were divided into three groups: Control group (FEV1 >75% predicted), mild (FEV1 60-75% predicted), moderate (FEV1 50-59% predicted), severe (FEV1<50% predicted). The preoperative pulmonary function indices were assessed as predictors, and postoperative morbidity was considered the surgical outcome. Results: This study included 566 consecutive patients. Patients with and without COPD were similar regarding baseline characteristics and clinical data. Hypertension, recent myocardial infarction, and low ejection fraction were higher in patients with different degrees of COPD than the control group while male gender was more frequent in control patients than the others. Restrictive lung disease and current cigarette smoking did not have any significant impact on postoperative complications. We found a borderline P = 0.057 with respect to respiratory failure among different patients of COPD severity so that 14.1% patients in control group, 23.5% in mild, 23.4% in moderate, and 21.9% in severe COPD categories developed respiratory failure after CABG surgery. Conclusion: Among post-CABG complications, patients with different levels of COPD based on STS definition, more frequently developed respiratory failure. This finding may imply the prognostic value of preoperative pulmonary function test for determining COPD severity and postoperative morbidities. scheduled for cardiac surgery, has a wide range: From 5.7% to more than 25%. The role of COPD in predicting an adverse outcome after coronary artery bypass graft surgery (CABG)

Research paper thumbnail of Effect of migraine on economic status and quality of life of patients

Tehran University Medical Journal

Research paper thumbnail of Updates on coagulation management in cardiac surgery

The journal of Tehran Heart Center, 2014

This paper should be cited as: Najafi M, Faraoni D. Updates on Coagulation Management in Cardiac ... more This paper should be cited as: Najafi M, Faraoni D. Updates on Coagulation Management in Cardiac Surgery. J Teh Univ Heart Ctr 2014;9(3):99-103.

Research paper thumbnail of Discriminative Power of EuroSCORE in Predicting Morbidity and Prolonged Hospital Stay in an Iranian Sample Population

The journal of Tehran Heart Center, Jan 12, 2014

The EuroSCORE is a simple and rigorous risk stratification model and is, thus, commonly used in p... more The EuroSCORE is a simple and rigorous risk stratification model and is, thus, commonly used in predicting the early and late outcomes of cardiac surgery across the world. We aimed to assess the discriminative power of the EuroSCORE model to predict postoperative morbidity and total prolonged length of stay in hospital (LOS) and Intensive Care Unit (ICU) stay in an Iranian group of cardiac surgical population. In a prospective study, the additive EuroSCORE model was applied to 570 patients undergoing isolated coronary artery bypass grafting (CABG) at Tehran Heart Center. The discrimination power of the EuroSCORE model was tested by the area under the receiver operating characteristic (ROC) curve and the calibration by comparing the observed and predicted outcomes across the risk spectrum assessed using the Hosmer-Lemeshow goodness-of-fit test. The mean age was 59.03 ± 0.73 years and 429 out of the 570 (75.3%) patients were men. The overall morbidity rate was 47.5%. The observed morb...

Research paper thumbnail of Plausible impact of dietary habits on reduced blood sugar in diabetic opium addicts with coronary artery disease

International cardiovascular research journal, 2012

The effect of opium on glycemic control in diabetics is a controversial issue, as some studies ha... more The effect of opium on glycemic control in diabetics is a controversial issue, as some studies have shown glucose lowering effect of opium in diabetes while the results of other studies do not support this idea. The possible role of opioid peptides in the regulation of food intake has been previously investigated. However, there is no data available about relationship between opium using and dietary pattern. The aim of the present study was to determine the daily intake of different nutrients in opium addict with diabetes diagnosed with coronary artery disease (CAD). This study comprised 232 consecutive diabetic patients with CAD, and candidates for isolated coronary artery bypass surgery in Tehran Heart Center. Of these, 26 patients were opium addicts. Nutritional assessment was obtained by a validated semi-quantitative food frequency questionnaire (FFQ). In opium addicts compared to non-addicts, consumption of carbohydrates (360.0±120.9 versus 447.8±249.8 Gr/day, P=0.016) and vita...

Research paper thumbnail of Serum creatinine role in predicting outcome after cardiac surgery beyond acute kidney injury

World Journal of Cardiology, 2014

Serum creatinine is still the most important determinant in the assessment of perioperative renal... more Serum creatinine is still the most important determinant in the assessment of perioperative renal function and in the prediction of adverse outcome in cardiac surgery. Many biomarkers have been studied to date; still, there is no surrogate for serum creatinine measurement in clinical practice because it is feasible and inexpensive. High levels of serum creatinine and its equivalents have been the most important preoperative risk factor for postoperative renal injury. Moreover, creatinine is the mainstay in predicting risk models and risk factor reduction has enhanced its importance in outcome prediction. The future perspective is the development of new definitions and novel tools for the early diagnosis of acute kidney injury largely based on serum creatinine and a panel of novel biomarkers.

Research paper thumbnail of Commentary on: Use of Remifentanil and Alfentanil in Endotracheal Intubation: A Comparative Study

Anesthesiology and Pain Medicine, 2012

Research paper thumbnail of SORT maneuver for nasogastric tube insertion

Research paper thumbnail of Prevention of tooth and gum damage: an oft neglected advantage of indirect laryngoscopy with Airtraq

Research paper thumbnail of Relationship between serum magnesium level and post coronary artery bypass graft surgery arrhythmias: A-757

European Journal of Anaesthesiology, 2006

Introduction: Atrial and ventricular arrhythmias are among the most common complications after co... more Introduction: Atrial and ventricular arrhythmias are among the most common complications after coronary artery bypass graft (CABG) surgery. It is known that cardiopulmonary bypass reduces serum magnesium level. In this study, we evaluated the relationship between total blood magnesium level (TMG) and the incidence of perioperative arrhythmias.

Research paper thumbnail of Updates on Coagulation Management in Cardiac Surgery

Journal of Tehran University Heart Center, Jul 1, 2014

This paper should be cited as: Najafi M, Faraoni D. Updates on Coagulation Management in Cardiac ... more This paper should be cited as: Najafi M, Faraoni D. Updates on Coagulation Management in Cardiac Surgery. J Teh Univ Heart Ctr 2014;9(3):99-103.

Research paper thumbnail of Interactive web-based lifestyle intervention and metabolic syndrome: findings from the Red Ruby (a randomized controlled trial)

Trials, 2015

Background: Metabolic syndrome is a growing public health problem worldwide. Several intervention... more Background: Metabolic syndrome is a growing public health problem worldwide. Several interventions have been proposed to specifically target the problem. This study evaluated the effectiveness of an interactive web-based lifestyle for management of metabolic syndrome. Methods: This randomized controlled trial was conducted from June through August 2012 in Tehran, Iran. Participants were individuals with metabolic syndrome who had registered on the study website. Interested eligible participants were invited for a free clinic visit and clinical assessment. They were randomly assigned to the intervention (n = 80) or control (n = 80) group. The intervention group received an interactive web-based program called the Healthy Heart Profile and were followed for 6 months. The control group received general information on metabolic syndrome. Anthropometric measures, glycemic status, and lipid profile were evaluated at baseline, and at 3-and 6-month follow-up assessments. Metabolic syndrome was defined according to The National Cholesterol Education Program Adult Treatment Panel (ATP) III report except for waist circumference, which was modified to ≥90 cm for both genders for the Iranian population.

Research paper thumbnail of Under- and overreporting of energy in a group of candidates for CABG surgery and its association with some anthropometric and sociodemographic factors, Tehran, Iran

Vascular Health and Risk Management

Numerous studies have documented a high prevalence of misreporting energy intakes. This paper exa... more Numerous studies have documented a high prevalence of misreporting energy intakes. This paper examines the prevalence of under- and overreporting of energy intake in a group of candidates for coronary artery bypass graft (CABG) surgery and its association with body mass index (BMI) and some sociodemographic factors. Dietary assessment (using a food frequency questionnaire) and demographic evaluation of 449 CABG surgery candidates was performed. Weight and height was also measured. McCrory equation was used to identify inaccurate records of energy intake. With this equation, reporting energy intake less than 78% and more than 122% of predicted energy expenditure was considered as under- and overreporting, respectively. Less than half of the participants reported energy intakes within the plausible limits. There were more overreporters than underreporters in this sample. The only significant association between misreporting and related factors was seen in BMI groups. As BMI increased,...

Research paper thumbnail of Construct, Validity and Reliability of Anesthesiology Problem Score Questionnaire

Research paper thumbnail of Quantitative measurement and ranking of occupational stressors: a preliminary study in anesthesiology residents

Research paper thumbnail of Fast-track method in cardiac surgery: Evaluation of risks and benefits of continuous administration technique

Singapore medical journal

Introduction: Fast-track is a method proposed to decrease medical costs through the reduction of ... more Introduction: Fast-track is a method proposed to decrease medical costs through the reduction of patients' length of stay in the hospital. This study was carried out to assess the risks and benefits of conducting the fast-track method in cardiac anaesthesia and to evaluate the role of continuous infusion of short-acting anaesthetics in a successful fast-track protocol. Methods: 100 cases were divided into two groups. In the fast-track group, fentanyl and propofol infusions were started at induction time and atracurium one hour later. No bolus drug was administered during the operation. Fentanyl infusion was continued up to 12 hours after surgery. The conventional extubation group received fentanyl and pancuronium as bolus doses. The two groups were evaluated for time of alertness and extubation in the intensive care unit, total analgesic dosage administered during the 24 hours after operation, arterial blood gas and peripheral saturation of oxygen before and after extubation. Re...

Research paper thumbnail of Relationship between serum magnesium level and post coronary artery bypass graft surgery arrhythmias

European Journal of Anaesthesiology

Introduction: Atrial and ventricular arrhythmias are among the most common complications after co... more Introduction: Atrial and ventricular arrhythmias are among the most common complications after coronary artery bypass graft (CABG) surgery. It is known that cardiopulmonary bypass reduces serum magnesium level. In this study, we evaluated the relationship between total blood magnesium level (TMG) and the incidence of perioperative arrhythmias.

Research paper thumbnail of Discriminative Power of EuroSCORE in Predicting Morbidity and Prolonged Hospital Stay in an Iranian Sample Population

Journal of Tehran University Heart Center

The EuroSCORE is a simple and rigorous risk stratification model and is, thus, commonly used in p... more The EuroSCORE is a simple and rigorous risk stratification model and is, thus, commonly used in predicting the early and late outcomes of cardiac surgery across the world. We aimed to assess the discriminative power of the EuroSCORE model to predict postoperative morbidity and total prolonged length of stay in hospital (LOS) and Intensive Care Unit (ICU) stay in an Iranian group of cardiac surgical population. In a prospective study, the additive EuroSCORE model was applied to 570 patients undergoing isolated coronary artery bypass grafting (CABG) at Tehran Heart Center. The discrimination power of the EuroSCORE model was tested by the area under the receiver operating characteristic (ROC) curve and the calibration by comparing the observed and predicted outcomes across the risk spectrum assessed using the Hosmer-Lemeshow goodness-of-fit test. The mean age was 59.03 ± 0.73 years and 429 out of the 570 (75.3%) patients were men. The overall morbidity rate was 47.5%. The observed morb...

Research paper thumbnail of Can a New Antiseptic Agent Reduce the Bacterial Colonization Rate of Central Venous Lines in PostCardiac Surgery Patients?

Journal of Tehran University Heart Center

Background: Central venous (CV) catheters play an essential role in the management of critically ... more Background: Central venous (CV) catheters play an essential role in the management of critically ill patients in the Intensive Care Unit (ICU). CV lines are, however, allied to catheter-associated blood stream infections. Bacterial colonization of CV lines is deemed the main cause of catheter-associated infection. The purpose of our study was to compare bacterial colony counts in the catheter site before CV line insertion in two groups of post-cardiac surgery patients: a group receiving Sanosil (an antiseptic agent composed of H2O2 and silver) and a control group. Methods: This interventional prospective double-blinded clinical trial recruited the patients in three post-cardiac surgery ICUs of a heart center. The participants were divided into interventional (113 patients) and control (136 patients) groups. Sanosil was added to the routine preparation procedure (Chlorhexidine bath one day before and scrub with Povidone-Iodine just before the CV line insertion). After the removal of ...

Research paper thumbnail of Do the metabolic syndrome associated with impaired Health Related Quality Of Life among People with Metabolic Syndrome ? A web-Based Study

Research paper thumbnail of Do preoperative pulmonary function indices predict morbidity after coronary artery bypass surgery?

Annals of Cardiac Anaesthesia, 2015

The reported prevalence of chronic obstructive pulmonary disease (COPD) varies among different gr... more The reported prevalence of chronic obstructive pulmonary disease (COPD) varies among different groups of cardiac surgical patients. Moreover, the prognostic value of preoperative COPD in outcome prediction is controversial. Aims: The present study assessed the morbidity in the different levels of COPD severity and the role of pulmonary function indices in predicting morbidity in patients undergoing coronary artery bypass graft (CABG). Settings and Design: Patients who were candidates for isolated CABG with cardiopulmonary bypass who were recruited for Tehran Heart Center-Coronary Outcome Measurement Study. Methods: Based on spirometry findings, diagnosis of COPD was considered based on Global Initiative for Chronic Obstructive Lung Disease category as forced expiratory volume in 1 s [FEV1]/forced vital capacity <0.7 (absolute value, not the percentage of the predicted). Society of Thoracic Surgeons (STS) definition was used for determining COPD severity and the patients were divided into three groups: Control group (FEV1 >75% predicted), mild (FEV1 60-75% predicted), moderate (FEV1 50-59% predicted), severe (FEV1<50% predicted). The preoperative pulmonary function indices were assessed as predictors, and postoperative morbidity was considered the surgical outcome. Results: This study included 566 consecutive patients. Patients with and without COPD were similar regarding baseline characteristics and clinical data. Hypertension, recent myocardial infarction, and low ejection fraction were higher in patients with different degrees of COPD than the control group while male gender was more frequent in control patients than the others. Restrictive lung disease and current cigarette smoking did not have any significant impact on postoperative complications. We found a borderline P = 0.057 with respect to respiratory failure among different patients of COPD severity so that 14.1% patients in control group, 23.5% in mild, 23.4% in moderate, and 21.9% in severe COPD categories developed respiratory failure after CABG surgery. Conclusion: Among post-CABG complications, patients with different levels of COPD based on STS definition, more frequently developed respiratory failure. This finding may imply the prognostic value of preoperative pulmonary function test for determining COPD severity and postoperative morbidities. scheduled for cardiac surgery, has a wide range: From 5.7% to more than 25%. The role of COPD in predicting an adverse outcome after coronary artery bypass graft surgery (CABG)

Research paper thumbnail of Effect of migraine on economic status and quality of life of patients

Tehran University Medical Journal

Research paper thumbnail of Updates on coagulation management in cardiac surgery

The journal of Tehran Heart Center, 2014

This paper should be cited as: Najafi M, Faraoni D. Updates on Coagulation Management in Cardiac ... more This paper should be cited as: Najafi M, Faraoni D. Updates on Coagulation Management in Cardiac Surgery. J Teh Univ Heart Ctr 2014;9(3):99-103.

Research paper thumbnail of Discriminative Power of EuroSCORE in Predicting Morbidity and Prolonged Hospital Stay in an Iranian Sample Population

The journal of Tehran Heart Center, Jan 12, 2014

The EuroSCORE is a simple and rigorous risk stratification model and is, thus, commonly used in p... more The EuroSCORE is a simple and rigorous risk stratification model and is, thus, commonly used in predicting the early and late outcomes of cardiac surgery across the world. We aimed to assess the discriminative power of the EuroSCORE model to predict postoperative morbidity and total prolonged length of stay in hospital (LOS) and Intensive Care Unit (ICU) stay in an Iranian group of cardiac surgical population. In a prospective study, the additive EuroSCORE model was applied to 570 patients undergoing isolated coronary artery bypass grafting (CABG) at Tehran Heart Center. The discrimination power of the EuroSCORE model was tested by the area under the receiver operating characteristic (ROC) curve and the calibration by comparing the observed and predicted outcomes across the risk spectrum assessed using the Hosmer-Lemeshow goodness-of-fit test. The mean age was 59.03 ± 0.73 years and 429 out of the 570 (75.3%) patients were men. The overall morbidity rate was 47.5%. The observed morb...

Research paper thumbnail of Plausible impact of dietary habits on reduced blood sugar in diabetic opium addicts with coronary artery disease

International cardiovascular research journal, 2012

The effect of opium on glycemic control in diabetics is a controversial issue, as some studies ha... more The effect of opium on glycemic control in diabetics is a controversial issue, as some studies have shown glucose lowering effect of opium in diabetes while the results of other studies do not support this idea. The possible role of opioid peptides in the regulation of food intake has been previously investigated. However, there is no data available about relationship between opium using and dietary pattern. The aim of the present study was to determine the daily intake of different nutrients in opium addict with diabetes diagnosed with coronary artery disease (CAD). This study comprised 232 consecutive diabetic patients with CAD, and candidates for isolated coronary artery bypass surgery in Tehran Heart Center. Of these, 26 patients were opium addicts. Nutritional assessment was obtained by a validated semi-quantitative food frequency questionnaire (FFQ). In opium addicts compared to non-addicts, consumption of carbohydrates (360.0±120.9 versus 447.8±249.8 Gr/day, P=0.016) and vita...

Research paper thumbnail of Serum creatinine role in predicting outcome after cardiac surgery beyond acute kidney injury

World Journal of Cardiology, 2014

Serum creatinine is still the most important determinant in the assessment of perioperative renal... more Serum creatinine is still the most important determinant in the assessment of perioperative renal function and in the prediction of adverse outcome in cardiac surgery. Many biomarkers have been studied to date; still, there is no surrogate for serum creatinine measurement in clinical practice because it is feasible and inexpensive. High levels of serum creatinine and its equivalents have been the most important preoperative risk factor for postoperative renal injury. Moreover, creatinine is the mainstay in predicting risk models and risk factor reduction has enhanced its importance in outcome prediction. The future perspective is the development of new definitions and novel tools for the early diagnosis of acute kidney injury largely based on serum creatinine and a panel of novel biomarkers.

Research paper thumbnail of Commentary on: Use of Remifentanil and Alfentanil in Endotracheal Intubation: A Comparative Study

Anesthesiology and Pain Medicine, 2012