Reza Taslimi | Tehran University of Medical Sciences (original) (raw)
Papers by Reza Taslimi
Medical journal of the Islamic Republic of Iran, 2014
Currently, non-invasive methods for screening atrophic gastritis and gastric cancer are lacking. ... more Currently, non-invasive methods for screening atrophic gastritis and gastric cancer are lacking. The purpose of this study was to evaluate the value of serological parameters including serum pepsinogen I (PGI), pepsinogen II (PGII) and pepsinogen I: II ratio for the screening atrophic gastritis and gastric cancer. The study population consisted of 132 dyspeptic patients who had undergone upper endoscopy with biopsy. Blood samples for ELISA assays of serum PGI, PGII and IgG antibodies against Helicobacter pylori were drawn. Comparison between the two groups was done by Student's t- test, and Mann Whitney test. Cut-off points were calculated using receiver operating curves (ROC). Mean (±SD) age of the study population was 51.4 (±15.5) years. Values of PGI and PG ratio decreased significantly in the atrophic gastritis as compared with the control group (p<0.05). Values of PG and PG ratio didn't show any significant difference between the gastric cancer and control group (p&g...
Anesthesia & Analgesia, 1995
Clonidine in spinal and epidural blocks prolongs anesthesia, but can cause hypotension and bradyc... more Clonidine in spinal and epidural blocks prolongs anesthesia, but can cause hypotension and bradycardia. The aim of our study was to compare hemodynamic and analgesic effects of spinal versus epidural clonidine alone and after repetitive dosing. In a prospective, randomized, double-blind study, we evaluated 40 patients scheduled for lower extremity orthopedic surgery under continuous spinal or epidural anesthesia with bupivacaine 0.5% (initial dose 5 mg and 50 mg, respectively). In either spinal or epidural technique one-half of patients received clonidine (150 micrograms) in addition to bupivacaine. Repeat doses of the same anesthetic mixture were allowed in cases of subsequent pain. Mean arterial pressure (MAP) and heart rate were recorded for 6 h after each injection. Duration of clinically useful anesthesia was defined as the time from drug administration to first sensation of pain. Intrathecal, but not epidural, clonidine decreased MAP significantly compared with bupivacaine alone. MAP after intrathecal clonidine with bupivacaine was lower than epidural clonidine with bupivacaine 5 and 6 h after injection. Repetitive administration caused no further decrease in MAP. Onset time required to surgical anesthesia (sensory block of T11) did not differ among the four groups. Duration of spinal and epidural anesthesia was increased more than two fold by clonidine. In summary, the addition of clonidine prolongs analgesia by either route. These results may be explained by clonidine's sites of action in hemodynamic control and the density of bupivacaine-induced block.
Middle East journal of digestive diseases, 2011
Background and objectives: Spontaneous bacterial peritonitis (SBP) is a frequent and often fatal ... more Background and objectives: Spontaneous bacterial peritonitis (SBP) is a frequent and often fatal complication of ascites without a demonstrable intra abdominal cause. In adults, the organisms of SBP are usually gram-negative bacteria, but they may differ in children. Since these organisms are resistant to most antibiotics, identification of active antimicrobial agents and determination of resistance pattern are essential. The aim of the present study was also to determine the causative agents of SBP in children with liver disease and ascites, referred to pediatrics ward of Imam Khomeini hospital during 1384-85. Material and Methods: In this study, ascite samples were taken from 85 patients with liver disease and ascites of Emam Khomeini Hospital, pediatrics ward, and they were examined by direct test, culture on different media and biochemistry tests. Antibiogram tests by disk diffusion were done on each positive sample. Results: Of 85 examined samples, 32 bacterial and 2 yeast agen...
Medical Journal of the Islamic Republic of Iran, Mar 9, 2014
Approach to the small intestine has been difficult even with newer methods. Double-balloon entero... more Approach to the small intestine has been difficult even with newer methods. Double-balloon enteroscopy (DBE) has been created for diagnostic and therapeutic interventions in diseases of the small intestine. Small intestinal diseases have different etiologies in each country. The DBE has been introduced in recent years in Iran. Our aim was to study the indications and results of DBE in some academic centers in Iran. Fifty-five patients with symptoms and signs related to small intestine without definitive diagnosis but with previous workup were enrolled in the study. The DBE was performed in three different medical universities in Iran. The mean age of the patients that underwent the DBE was 47.2 ± 17.3 years. Abdominal pain (54.5%) and occult gastrointestinal bleeding (23.6%) were the most common presentations. Small bowel lesions were detected in 26 patients (47.3%); the most common lesions were ulcer (46.2%) and polyps (19.2%). Crohn&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s disease (12.7%) was the commonest diagnosis found in DBE procedure. Patients presenting with abdominal pain orl ower hemoglobin level were more likely to be diagnosed (both p≤ 0.05). Small intestinal diseases were ultimately diagnosed in 47.3% of the patients. Twenty percent of the patients had another disease outside the small bowel. DBE is an effective and relatively safe diagnostic and therapeutic option for small bowel evaluations. Accurate selection of patients and more experience technicians and physicians will improve the efficacy of this procedure in Iran.
Emergency Medicine Journal, 2013
Journal of Pathogens, 2015
Background. Helicobacter pylori is highly adapted to the gastric environment where it lives withi... more Background. Helicobacter pylori is highly adapted to the gastric environment where it lives within or beneath the gastric mucous layer. The aim of this study was to evaluate whether the addition of N-acetyl cysteine to the treatment regimen of H. pylori infection would affect eradication rates of the disease. Methods. A total of 79 H. pylori positive patients were randomized to two therapeutic groups. Both groups received a 14-day course of three-drug regimen including amoxicillin/clarithromycin/omeprazole. Experimental group (38 subjects) received NAC, and control group (41 subjects) received placebo, besides three-drug regimen. H. pylori eradication was evaluated by urea breath test at least 4 weeks after the cessation of therapy. Results. The rate of H. pylori eradication was 72.9% and 60.9% in experimental and control groups, respectively (P = 0.005). By logistic regression modeling, female gender (OR 3.68, 95% CI: 1.06-5.79; P = 0.040) and treatment including NAC (OR 1.88, 95% CI: 0.68-3.15; P = 0.021) were independent factors associated with H. pylori eradication. Conclusion. The results of the present study show that NAC has an additive effect on the eradication rates of H. pylori obtained with three-drug regimen and appears to be a promising means of eradicating H. pylori infection.
European Journal of Radiology Extra, 2006
A rare adult case of absent azygos vein associated with polysplenia syndrome who was admitted due... more A rare adult case of absent azygos vein associated with polysplenia syndrome who was admitted due to pulmonary emboli is presented, image findings are described and embryological bases of venous abnormalities and its association with coagulopathy is discussed via reviewing literatures.
Medical journal of the Islamic Republic of Iran, 2014
Background Sulfur mustard (SM) has acute and chronic effects on skin and mucosal surfaces. The ai... more Background Sulfur mustard (SM) has acute and chronic effects on skin and mucosal surfaces. The aim of the study was to evaluate the frequency of esophagitis in a historical cohort of veterans who had been exposed to SM in Iran-Iraq war nearly 25 years ago. One hundred two veterans with dyspepsia and/or heartburn underwent esophago-gastroduodenoscopy. Of them, 52 cases had been exposed to SM and had chronic mustard lung disease. Controls included 50 veterans without SM exposure. Esophagitis was defined according to standard criteria. 81.6% of cases and 70.6% of controls had heart burn and/or regurgitation (p= 0.224). Esophagitis was seen in 40% of cases and 26.5% of controls (p= 0.155). Based on our findings, SM exposure seems not to be associated with increased esophagitis.
Medical journal of the Islamic Republic of Iran, 2014
Approach to the small intestine has been difficult even with newer methods. Double-balloon entero... more Approach to the small intestine has been difficult even with newer methods. Double-balloon enteroscopy (DBE) has been created for diagnostic and therapeutic interventions in diseases of the small intestine. Small intestinal diseases have different etiologies in each country. The DBE has been introduced in recent years in Iran. Our aim was to study the indications and results of DBE in some academic centers in Iran. Fifty-five patients with symptoms and signs related to small intestine without definitive diagnosis but with previous workup were enrolled in the study. The DBE was performed in three different medical universities in Iran. The mean age of the patients that underwent the DBE was 47.2 ± 17.3 years. Abdominal pain (54.5%) and occult gastrointestinal bleeding (23.6%) were the most common presentations. Small bowel lesions were detected in 26 patients (47.3%); the most common lesions were ulcer (46.2%) and polyps (19.2%). Crohn's disease (12.7%) was the commonest diagnosi...
Medical journal of the Islamic Republic of Iran, 2014
Here, we present a case of a 78-year-old man that underwent gastrointestinal endoscopy because of... more Here, we present a case of a 78-year-old man that underwent gastrointestinal endoscopy because of one- month history of dysphagia to liquids and solid foods with accompanying weight loss. On endoscopy, there was distal esophageal stenosis. Multiple biopsies were obtained. Histologic examination of the samples revealed normal tissue. The stenosis was treated by dilatation and abdomino pelvic computed tomography scanning was performed to search for an underlying malignant lesion that showed a mass adjacent to distal esophagus. We did endosonography- guided fine needle aspiration of the mass. It was a squamous cell carcinoma (SCC). Malignancy is a challenging diagnosis in patients with dysphagia and near normal endoscopy. To our knowledge, there are a few reports of SCC to cause it.
Middle East journal of digestive diseases, 2012
... Reza Taslimi 1٭, Mohsen Esfandbod 2, Minoo Mohraz 3, Masoud Soutodeh 4, Hadi Rokni5 ... Mycob... more ... Reza Taslimi 1٭, Mohsen Esfandbod 2, Minoo Mohraz 3, Masoud Soutodeh 4, Hadi Rokni5 ... Mycobacterium avium intracellular (MAI) infections, fungal infec-tions like actinomycosis Israeli or blastomy-cosis can produce liver masses and also lung infiltrates but in this case the ...
European Journal of Radiology Extra, 2006
A rare adult case of absent azygos vein associated with polysplenia syndrome who was admitted due... more A rare adult case of absent azygos vein associated with polysplenia syndrome who was admitted due to pulmonary emboli is presented, image findings are described and embryological bases of venous abnormalities and its association with coagulopathy is discussed via reviewing literatures.
Clinical Rheumatology, 2013
Fibrodysplasia ossificans progressiva (FOP) is a rare catastrophic genetic condition of extraskel... more Fibrodysplasia ossificans progressiva (FOP) is a rare catastrophic genetic condition of extraskeletal (heterotopic) ossification. One in every two million people is affected worldwide, with no ethnic, racial, gender, or geographic predisposition. Most cases of FOP arise from a spontaneous missense mutation in the gene encoding bone morphogenic protein (BMP) type II receptor (ACVR1/ALK2). Affected individuals are normal at birth apart from malformed great toes. Onset of clinical symptoms is usually in the first decade of life, presenting with episodic emergence of painful rapidly appearing tumor-like soft tissue swellings (flare-ups). Heterotopic bone replaces the skeletal muscles, tendons, ligaments, and connective tissue at the site of the damage through a process of endochondral ossification, causing fixation of joints and permanent limitation of motion. Most affected individuals are confined to wheelchair in the third decade of life. Worldwide rate of misdiagnosis of FOP is very high; clinicians often fail to associate the two classic clinical features of FOP: rapidly developing soft tissue swellings and the abnormal great toes. The current case presents a previously undiagnosed 39-year-old FOP patient, sadly a victim of lack of clinical awareness of this rare condition. As a result of repetitive iatrogenic harm, he has tragically &amp;amp;amp;quot;turned into stone.&amp;amp;amp;quot;
Cases Journal, 2009
A lost guidewire is a hazardous, yet completely preventable, and rare complication associated wit... more A lost guidewire is a hazardous, yet completely preventable, and rare complication associated with central venous catheter insertion. Here, we report a case of a lost guidewire in a patient presented with persistent abdominal pain. The guidewire was retrieved completely during a surgical operation after the diagnosis had been confirmed by radiologic studies. Following some tips during insertion of a central venous catheter will help to prevent this mortal complication or at least, in rapid diagnosis of its loss. Interventional radiologic techniques are now readily used to retrieve a lost guidewire.
Anesthesia & Analgesia, 1999
The American Journal of Emergency Medicine, 2011
Congenital fibrinogen disorders are rare in emergency departments (EDs). We describe 2 cases with... more Congenital fibrinogen disorders are rare in emergency departments (EDs). We describe 2 cases with different presentations; the first was a 27-year-old woman with a known case of congenital hypofibrinogenemia who presented with nausea, vomiting, abdominal pain, and distension. She reported a history of concentrated fibrinogen use (1000 mg/d) for 4 days without visiting any physician. She was diagnosed as having thrombosis of mesenteric and portal veins with intestinal ischemia. The second was a 28-year-old woman with congenital afibrinogenemia who came to our ED with abdominal pain. She was diagnosed as having spontaneous rupture of spleen. Because of various presentations of patients with congenital fibrinogen disorders, both hemorrhagic and thrombotic events should be considered. 0735-6757/$see front matter
DARU Journal of Pharmaceutical Sciences, 2009
Abstract: Background and Purpose of the study: Hyperglycemia and insulin resistance are common fi... more Abstract: Background and Purpose of the study: Hyperglycemia and insulin resistance are common findings among critically ill patients. Intensive insulin therapy reduces morbidity and mortality in patients of surgical and medical intensive care units (ICUs), but its role in patients of general intensive care units still remains unknown. The present study was designed to determine the effect of intensive insulin therapy on ICU mortality.] Methods: Adult patients admitted to general intensive care units in Valiy-e-Asr Hospital, who ...
Medical Journal of the Islamic Republic of Iran, 2014
BACKGROUND: Currently, non-invasive methods for screening atrophic gastritis and gastric cancer a... more BACKGROUND: Currently, non-invasive methods for screening atrophic gastritis and gastric cancer are lacking. The purpose of this study was to evaluate the value of serological parameters including serum pepsinogen I (PGI), pepsinogen II (PGII) and pepsinogen I: II ratio for the screening atrophic gastritis and gastric cancer.METHODS: The study population consisted of 132 dyspeptic patients who had undergone upper endoscopy with biopsy. Blood samples for ELISA assays of serum PGI, PGII and IgG antibodies against Helicobacter pylori were drawn. Comparison between the two groups was done by Student's t- test, and Mann Whitney test. Cut-off points were calculated using receiver operating curves (ROC).RESULTS: Mean (±SD) age of the study population was 51.4 (±15.5) years. Values of PGI and PG ratio decreased significantly in the atrophic gastritis as compared with the control group (p<0.05). Values of PG and PG ratio didn't show any significant difference between the gastric cancer and control group (p>0.05). For patients with atrophic gastritis, the area under the ROC for PGI was 0.639 (95% CI:0.538-0.741, p=0.008) in which the best cut-off value was 40μg/L (sensitivity 90%, specificity 67%, accuracy 69%, negative predictive value 92%, YI : 0.429). The area under the ROC for PG ratio was 0.711 (95% CI: 0.617-0.806, p=0.0001) and the best cut-off value was 8 (sensitivity 71%, specificity 71%, accuracy 71%, negative predictive value 86%,YI : 0.431).CONCLUSION: It seems that PGI, PGI: PGII ratio is potential biomarkers for screening atrophic gastritis with high sensitivity, specificity, accuracy and negative predictive value. Serology could be used as a screening method for the detection of precancerous states due to its convenience, relative low cost and safety.
Medical journal of the Islamic Republic of Iran, 2014
Currently, non-invasive methods for screening atrophic gastritis and gastric cancer are lacking. ... more Currently, non-invasive methods for screening atrophic gastritis and gastric cancer are lacking. The purpose of this study was to evaluate the value of serological parameters including serum pepsinogen I (PGI), pepsinogen II (PGII) and pepsinogen I: II ratio for the screening atrophic gastritis and gastric cancer. The study population consisted of 132 dyspeptic patients who had undergone upper endoscopy with biopsy. Blood samples for ELISA assays of serum PGI, PGII and IgG antibodies against Helicobacter pylori were drawn. Comparison between the two groups was done by Student's t- test, and Mann Whitney test. Cut-off points were calculated using receiver operating curves (ROC). Mean (±SD) age of the study population was 51.4 (±15.5) years. Values of PGI and PG ratio decreased significantly in the atrophic gastritis as compared with the control group (p<0.05). Values of PG and PG ratio didn't show any significant difference between the gastric cancer and control group (p&g...
Anesthesia & Analgesia, 1995
Clonidine in spinal and epidural blocks prolongs anesthesia, but can cause hypotension and bradyc... more Clonidine in spinal and epidural blocks prolongs anesthesia, but can cause hypotension and bradycardia. The aim of our study was to compare hemodynamic and analgesic effects of spinal versus epidural clonidine alone and after repetitive dosing. In a prospective, randomized, double-blind study, we evaluated 40 patients scheduled for lower extremity orthopedic surgery under continuous spinal or epidural anesthesia with bupivacaine 0.5% (initial dose 5 mg and 50 mg, respectively). In either spinal or epidural technique one-half of patients received clonidine (150 micrograms) in addition to bupivacaine. Repeat doses of the same anesthetic mixture were allowed in cases of subsequent pain. Mean arterial pressure (MAP) and heart rate were recorded for 6 h after each injection. Duration of clinically useful anesthesia was defined as the time from drug administration to first sensation of pain. Intrathecal, but not epidural, clonidine decreased MAP significantly compared with bupivacaine alone. MAP after intrathecal clonidine with bupivacaine was lower than epidural clonidine with bupivacaine 5 and 6 h after injection. Repetitive administration caused no further decrease in MAP. Onset time required to surgical anesthesia (sensory block of T11) did not differ among the four groups. Duration of spinal and epidural anesthesia was increased more than two fold by clonidine. In summary, the addition of clonidine prolongs analgesia by either route. These results may be explained by clonidine's sites of action in hemodynamic control and the density of bupivacaine-induced block.
Middle East journal of digestive diseases, 2011
Background and objectives: Spontaneous bacterial peritonitis (SBP) is a frequent and often fatal ... more Background and objectives: Spontaneous bacterial peritonitis (SBP) is a frequent and often fatal complication of ascites without a demonstrable intra abdominal cause. In adults, the organisms of SBP are usually gram-negative bacteria, but they may differ in children. Since these organisms are resistant to most antibiotics, identification of active antimicrobial agents and determination of resistance pattern are essential. The aim of the present study was also to determine the causative agents of SBP in children with liver disease and ascites, referred to pediatrics ward of Imam Khomeini hospital during 1384-85. Material and Methods: In this study, ascite samples were taken from 85 patients with liver disease and ascites of Emam Khomeini Hospital, pediatrics ward, and they were examined by direct test, culture on different media and biochemistry tests. Antibiogram tests by disk diffusion were done on each positive sample. Results: Of 85 examined samples, 32 bacterial and 2 yeast agen...
Medical Journal of the Islamic Republic of Iran, Mar 9, 2014
Approach to the small intestine has been difficult even with newer methods. Double-balloon entero... more Approach to the small intestine has been difficult even with newer methods. Double-balloon enteroscopy (DBE) has been created for diagnostic and therapeutic interventions in diseases of the small intestine. Small intestinal diseases have different etiologies in each country. The DBE has been introduced in recent years in Iran. Our aim was to study the indications and results of DBE in some academic centers in Iran. Fifty-five patients with symptoms and signs related to small intestine without definitive diagnosis but with previous workup were enrolled in the study. The DBE was performed in three different medical universities in Iran. The mean age of the patients that underwent the DBE was 47.2 ± 17.3 years. Abdominal pain (54.5%) and occult gastrointestinal bleeding (23.6%) were the most common presentations. Small bowel lesions were detected in 26 patients (47.3%); the most common lesions were ulcer (46.2%) and polyps (19.2%). Crohn&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s disease (12.7%) was the commonest diagnosis found in DBE procedure. Patients presenting with abdominal pain orl ower hemoglobin level were more likely to be diagnosed (both p≤ 0.05). Small intestinal diseases were ultimately diagnosed in 47.3% of the patients. Twenty percent of the patients had another disease outside the small bowel. DBE is an effective and relatively safe diagnostic and therapeutic option for small bowel evaluations. Accurate selection of patients and more experience technicians and physicians will improve the efficacy of this procedure in Iran.
Emergency Medicine Journal, 2013
Journal of Pathogens, 2015
Background. Helicobacter pylori is highly adapted to the gastric environment where it lives withi... more Background. Helicobacter pylori is highly adapted to the gastric environment where it lives within or beneath the gastric mucous layer. The aim of this study was to evaluate whether the addition of N-acetyl cysteine to the treatment regimen of H. pylori infection would affect eradication rates of the disease. Methods. A total of 79 H. pylori positive patients were randomized to two therapeutic groups. Both groups received a 14-day course of three-drug regimen including amoxicillin/clarithromycin/omeprazole. Experimental group (38 subjects) received NAC, and control group (41 subjects) received placebo, besides three-drug regimen. H. pylori eradication was evaluated by urea breath test at least 4 weeks after the cessation of therapy. Results. The rate of H. pylori eradication was 72.9% and 60.9% in experimental and control groups, respectively (P = 0.005). By logistic regression modeling, female gender (OR 3.68, 95% CI: 1.06-5.79; P = 0.040) and treatment including NAC (OR 1.88, 95% CI: 0.68-3.15; P = 0.021) were independent factors associated with H. pylori eradication. Conclusion. The results of the present study show that NAC has an additive effect on the eradication rates of H. pylori obtained with three-drug regimen and appears to be a promising means of eradicating H. pylori infection.
European Journal of Radiology Extra, 2006
A rare adult case of absent azygos vein associated with polysplenia syndrome who was admitted due... more A rare adult case of absent azygos vein associated with polysplenia syndrome who was admitted due to pulmonary emboli is presented, image findings are described and embryological bases of venous abnormalities and its association with coagulopathy is discussed via reviewing literatures.
Medical journal of the Islamic Republic of Iran, 2014
Background Sulfur mustard (SM) has acute and chronic effects on skin and mucosal surfaces. The ai... more Background Sulfur mustard (SM) has acute and chronic effects on skin and mucosal surfaces. The aim of the study was to evaluate the frequency of esophagitis in a historical cohort of veterans who had been exposed to SM in Iran-Iraq war nearly 25 years ago. One hundred two veterans with dyspepsia and/or heartburn underwent esophago-gastroduodenoscopy. Of them, 52 cases had been exposed to SM and had chronic mustard lung disease. Controls included 50 veterans without SM exposure. Esophagitis was defined according to standard criteria. 81.6% of cases and 70.6% of controls had heart burn and/or regurgitation (p= 0.224). Esophagitis was seen in 40% of cases and 26.5% of controls (p= 0.155). Based on our findings, SM exposure seems not to be associated with increased esophagitis.
Medical journal of the Islamic Republic of Iran, 2014
Approach to the small intestine has been difficult even with newer methods. Double-balloon entero... more Approach to the small intestine has been difficult even with newer methods. Double-balloon enteroscopy (DBE) has been created for diagnostic and therapeutic interventions in diseases of the small intestine. Small intestinal diseases have different etiologies in each country. The DBE has been introduced in recent years in Iran. Our aim was to study the indications and results of DBE in some academic centers in Iran. Fifty-five patients with symptoms and signs related to small intestine without definitive diagnosis but with previous workup were enrolled in the study. The DBE was performed in three different medical universities in Iran. The mean age of the patients that underwent the DBE was 47.2 ± 17.3 years. Abdominal pain (54.5%) and occult gastrointestinal bleeding (23.6%) were the most common presentations. Small bowel lesions were detected in 26 patients (47.3%); the most common lesions were ulcer (46.2%) and polyps (19.2%). Crohn's disease (12.7%) was the commonest diagnosi...
Medical journal of the Islamic Republic of Iran, 2014
Here, we present a case of a 78-year-old man that underwent gastrointestinal endoscopy because of... more Here, we present a case of a 78-year-old man that underwent gastrointestinal endoscopy because of one- month history of dysphagia to liquids and solid foods with accompanying weight loss. On endoscopy, there was distal esophageal stenosis. Multiple biopsies were obtained. Histologic examination of the samples revealed normal tissue. The stenosis was treated by dilatation and abdomino pelvic computed tomography scanning was performed to search for an underlying malignant lesion that showed a mass adjacent to distal esophagus. We did endosonography- guided fine needle aspiration of the mass. It was a squamous cell carcinoma (SCC). Malignancy is a challenging diagnosis in patients with dysphagia and near normal endoscopy. To our knowledge, there are a few reports of SCC to cause it.
Middle East journal of digestive diseases, 2012
... Reza Taslimi 1٭, Mohsen Esfandbod 2, Minoo Mohraz 3, Masoud Soutodeh 4, Hadi Rokni5 ... Mycob... more ... Reza Taslimi 1٭, Mohsen Esfandbod 2, Minoo Mohraz 3, Masoud Soutodeh 4, Hadi Rokni5 ... Mycobacterium avium intracellular (MAI) infections, fungal infec-tions like actinomycosis Israeli or blastomy-cosis can produce liver masses and also lung infiltrates but in this case the ...
European Journal of Radiology Extra, 2006
A rare adult case of absent azygos vein associated with polysplenia syndrome who was admitted due... more A rare adult case of absent azygos vein associated with polysplenia syndrome who was admitted due to pulmonary emboli is presented, image findings are described and embryological bases of venous abnormalities and its association with coagulopathy is discussed via reviewing literatures.
Clinical Rheumatology, 2013
Fibrodysplasia ossificans progressiva (FOP) is a rare catastrophic genetic condition of extraskel... more Fibrodysplasia ossificans progressiva (FOP) is a rare catastrophic genetic condition of extraskeletal (heterotopic) ossification. One in every two million people is affected worldwide, with no ethnic, racial, gender, or geographic predisposition. Most cases of FOP arise from a spontaneous missense mutation in the gene encoding bone morphogenic protein (BMP) type II receptor (ACVR1/ALK2). Affected individuals are normal at birth apart from malformed great toes. Onset of clinical symptoms is usually in the first decade of life, presenting with episodic emergence of painful rapidly appearing tumor-like soft tissue swellings (flare-ups). Heterotopic bone replaces the skeletal muscles, tendons, ligaments, and connective tissue at the site of the damage through a process of endochondral ossification, causing fixation of joints and permanent limitation of motion. Most affected individuals are confined to wheelchair in the third decade of life. Worldwide rate of misdiagnosis of FOP is very high; clinicians often fail to associate the two classic clinical features of FOP: rapidly developing soft tissue swellings and the abnormal great toes. The current case presents a previously undiagnosed 39-year-old FOP patient, sadly a victim of lack of clinical awareness of this rare condition. As a result of repetitive iatrogenic harm, he has tragically &amp;amp;amp;quot;turned into stone.&amp;amp;amp;quot;
Cases Journal, 2009
A lost guidewire is a hazardous, yet completely preventable, and rare complication associated wit... more A lost guidewire is a hazardous, yet completely preventable, and rare complication associated with central venous catheter insertion. Here, we report a case of a lost guidewire in a patient presented with persistent abdominal pain. The guidewire was retrieved completely during a surgical operation after the diagnosis had been confirmed by radiologic studies. Following some tips during insertion of a central venous catheter will help to prevent this mortal complication or at least, in rapid diagnosis of its loss. Interventional radiologic techniques are now readily used to retrieve a lost guidewire.
Anesthesia & Analgesia, 1999
The American Journal of Emergency Medicine, 2011
Congenital fibrinogen disorders are rare in emergency departments (EDs). We describe 2 cases with... more Congenital fibrinogen disorders are rare in emergency departments (EDs). We describe 2 cases with different presentations; the first was a 27-year-old woman with a known case of congenital hypofibrinogenemia who presented with nausea, vomiting, abdominal pain, and distension. She reported a history of concentrated fibrinogen use (1000 mg/d) for 4 days without visiting any physician. She was diagnosed as having thrombosis of mesenteric and portal veins with intestinal ischemia. The second was a 28-year-old woman with congenital afibrinogenemia who came to our ED with abdominal pain. She was diagnosed as having spontaneous rupture of spleen. Because of various presentations of patients with congenital fibrinogen disorders, both hemorrhagic and thrombotic events should be considered. 0735-6757/$see front matter
DARU Journal of Pharmaceutical Sciences, 2009
Abstract: Background and Purpose of the study: Hyperglycemia and insulin resistance are common fi... more Abstract: Background and Purpose of the study: Hyperglycemia and insulin resistance are common findings among critically ill patients. Intensive insulin therapy reduces morbidity and mortality in patients of surgical and medical intensive care units (ICUs), but its role in patients of general intensive care units still remains unknown. The present study was designed to determine the effect of intensive insulin therapy on ICU mortality.] Methods: Adult patients admitted to general intensive care units in Valiy-e-Asr Hospital, who ...
Medical Journal of the Islamic Republic of Iran, 2014
BACKGROUND: Currently, non-invasive methods for screening atrophic gastritis and gastric cancer a... more BACKGROUND: Currently, non-invasive methods for screening atrophic gastritis and gastric cancer are lacking. The purpose of this study was to evaluate the value of serological parameters including serum pepsinogen I (PGI), pepsinogen II (PGII) and pepsinogen I: II ratio for the screening atrophic gastritis and gastric cancer.METHODS: The study population consisted of 132 dyspeptic patients who had undergone upper endoscopy with biopsy. Blood samples for ELISA assays of serum PGI, PGII and IgG antibodies against Helicobacter pylori were drawn. Comparison between the two groups was done by Student's t- test, and Mann Whitney test. Cut-off points were calculated using receiver operating curves (ROC).RESULTS: Mean (±SD) age of the study population was 51.4 (±15.5) years. Values of PGI and PG ratio decreased significantly in the atrophic gastritis as compared with the control group (p<0.05). Values of PG and PG ratio didn't show any significant difference between the gastric cancer and control group (p>0.05). For patients with atrophic gastritis, the area under the ROC for PGI was 0.639 (95% CI:0.538-0.741, p=0.008) in which the best cut-off value was 40μg/L (sensitivity 90%, specificity 67%, accuracy 69%, negative predictive value 92%, YI : 0.429). The area under the ROC for PG ratio was 0.711 (95% CI: 0.617-0.806, p=0.0001) and the best cut-off value was 8 (sensitivity 71%, specificity 71%, accuracy 71%, negative predictive value 86%,YI : 0.431).CONCLUSION: It seems that PGI, PGI: PGII ratio is potential biomarkers for screening atrophic gastritis with high sensitivity, specificity, accuracy and negative predictive value. Serology could be used as a screening method for the detection of precancerous states due to its convenience, relative low cost and safety.