Taraneh Yazdanparast | Tehran University of Medical Sciences (original) (raw)

Papers by Taraneh Yazdanparast

High‐frequency ultrasound evaluation of morphea: Retrospective analytical study

Skin research and technology, Jun 25, 2024

Contact allergens responsible for eyelid dermatitis in adults

Journal of dermatology, Feb 13, 2024

Journal of surgical dermatology, Jun 12, 2018

Hyaluronic acid fillers are considered safe for use in cosmetics as described in the safety asses... more Hyaluronic acid fillers are considered safe for use in cosmetics as described in the safety assessment. This study was aimed to assess and compare the efficacy and safety of two hyaluronic acid (HA) fillers on mild nasolabial folds. Ten women aged 30-50 years with mild nasolabial folds participated for injection of A and B gels into right or left nasolabial folds. The volume and surface of nasolabial folds were measured by CSI software and the density and thickness of dermis assessed by skin ultrasonography before and 2, 12, and 24 weeks after injection. The data were analyzed using SPSS software version 20, and p-value <0.05 were considered as significant. Global assessment showed over 50% improvement in patients injected with both gel A and B. At 2 weeks after injecting gel A the volume and surface of wrinkles decreased significantly. In the side injected with gel B, this reduction was significant at 2 and 12 weeks after injection. In addition, 24 weeks after injection of both gels the dermis echo-density increased and the dermis thickness decreased. This study indicated the significant positive filling effect of both HA fillers in decreasing the clinical signs of wrinkles at nasolabial folds. Comparing both fillers, there were not any statistically significant differences in any of measurements, but the persistence of gel B to improve the wrinkle appearance was slightly better than gel A.

PubMed, Mar 1, 2016

Recognizing patients at a higher risk of developing chronic low back pain (LBP) is important in i... more Recognizing patients at a higher risk of developing chronic low back pain (LBP) is important in industrial medicine. This study aimed to assess the power and quality of General Health Questionnaire (GHQ) for prediction of the odds of chronicity of acute LBP. This study was conducted on industrial workers. All subjects with acute LBP who met the inclusion criteria were enrolled. Demographic characteristics, occupational, physical, and mental parameters and the general health status of subjects were evaluated; they were followed up for developing chronic LBP for one year. Cigarette smoking, high body mass index, job stress, physical load and high GHQ scores were found to be the risk factors for the progression of acute LBP to chronic LBP (P<0.05). Standing position while working, age, work experience, exercise, level of education, weekly work hours and shift work were not the risk factors for chronic LBP (P>0.05). High GHQ score can be a risk factor for progression of acute LBP to chronic LBP. The GHQ in combination with the Job Content Questionnaire can be used as a quick and simple screening tool for detection of subjects at high risk of chronic LBP when evaluating acute LBP in an occupational setting.

Primary Care Respiratory Journal, Feb 25, 2013

Background: Quality improvement, standardisation of spirometry testing, and interpretation of res... more Background: Quality improvement, standardisation of spirometry testing, and interpretation of results are critically important in the occupational setting. Aims: To determine the quality of spirometry tests and pulmonary function changes in two consecutive years among the personnel of an industrial company. Methods: This study was performed in an oil refinery in Iran in 2011. Data on 1,004 male personnel were evaluated before and after a training course conducted according to the National Institute for Occupational Safety and Health guidelines. American Thoracic Society/European Respiratory Society guidelines were used for assessment of the acceptability and repeatability criteria. Results: The most common error in the first year of evaluation was forced vital capacity >6 seconds or a 1 second plateau. Acceptability and proper interpretation significantly improved after the course (p<0.05), but repeatability did not change significantly (p>0.05). Conclusions: The results of this study show that the validity and quality of spirometric tests conducted in the studied company in Iran were unacceptable, but these improved significantly after the training intervention. The study demonstrated the lack of a systematic guideline for conducting spirometry and interpreting the results in the occupational setting in Iran, and emphasises the need for a nationwide programme to improve the quality of spirometry tests in this setting.

Medical journal of the Islamic Republic of Iran, Sep 30, 2018

Skin biometrology is useful in evaluating inflammatory skin disorders such as dermatitis, psorias... more Skin biometrology is useful in evaluating inflammatory skin disorders such as dermatitis, psoriasis, and lichen planus. →What this article adds: Dermatitis, psoriasis and lichen planus lesions show specified biophysical changes that may help in differential diagnosis of them.

Challenges in Longitudinal Spirometry Data in Occupational Medicine: Spirometry Indices during Five Consecutive Years and its Causative Factors

PubMed, Mar 1, 2021

Background: Respiratory illnesses caused by occupational exposure have the most negative effects ... more Background: Respiratory illnesses caused by occupational exposure have the most negative effects on the workers' health status in workplaces. In occupations with a high likelihood of labor-induced pulmonary diseases, a periodic spirometry test is usually used to monitor occupational lung function and prevent occupational respiratory diseases. Monitoring workers exposed to occupational pulmonary diseases is widely done using forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) for early diagnosis of obstructive pulmonary and lung diseases. We assessed the usefulness of longitudinal data of periodic spirometry tests in a sulfate production industry. Materials and methods: In this longitudinal study, 212 individuals working in a sulfate production industry near Tehran were examined. Demographic data and information, such as FEV1, FVC, FEV1%, FVC%, and FEV1 / FVC ratio were obtained from 2009 to 2013. Data were analyzed using the SPSS software version 21. The one-way analysis of variance (ANOVA) and repeated measures ANOVA for data analysis. Results: The results showed that the variation of the spirometry parameters over 5 years was significant. The factors studied not only decreased in some years but also increased in comparison with the previous year. Also, the average FEV1 and FVC and also FEV1 / FVC significantly was different at different time points [F(2.864, 590.029)= 27.269, P < .0001], [F(2.910, 599.546)= 38.239, P < .0001], and [F(3.257, 671.019)= 13.351, P < .0001]. Conclusion: The best spirometry tests, not only acceptable tests, are important in longitudinal spirometry evaluations. There is no systematic supervision on spirometry tests in Iran and the results of this study reflect a serious need for such supervision.

Biophysical and ultrasonographic changes in pityriasis rosea compared with uninvolved skin

International Journal of Women's Dermatology, Jun 1, 2021

Background Pityriasis rosea (PR) is a common, self-limited, inflammatory papulosquamous skin dise... more Background Pityriasis rosea (PR) is a common, self-limited, inflammatory papulosquamous skin disease with a possible viral etiology. Objective The goal of this study was to evaluate skin biophysical properties in patients with PR compared with uninvolved skin to better understand the pathogenesis of PR. Methods Stratum corneum hydration, transepidermal water loss, surface friction, pH, sebum, melanin, erythema, temperature, elasticity parameters (R0, R2, R5), thickness, and echodensity of the epidermis and dermis were measured on lesions of classic PR in 21 patients and compared with control sites (average of uninvolved perilesional and symmetrical skin) with a paired t test. Results Stratum corneum hydration (p < .001), R0 (p = .003), R2 (p = .001), R5 (p = .003), and echodensity of the dermis (p = .006) were significantly lower, whereas transepidermal water loss (p = .001), pH (p < .001), and erythema (p < .001) were significantly higher in PR lesions. There was no significant difference in friction index, sebum, melanin content, temperature, thickness of the epidermis and dermis, and echodensity of the epidermis between PR and normal skin. Conclusion PR skin is characterized by certain alterations in biophysical properties, which are mostly correlated with histologic changes. These changes may be helpful in early, noninvasive diagnosis of PR.

Stratum corneum hydration in healthy adult humans according to the skin area, age and sex: a systematic review and meta‐analysis

Journal of The European Academy of Dermatology and Venereology, Jun 22, 2022

Stratum corneum (SC) hydration is one of the most important skin biophysical parameters, which is... more Stratum corneum (SC) hydration is one of the most important skin biophysical parameters, which is affected by age, sex and anatomic site. We conducted a systematic review and meta‐analysis to provide detailed information on baseline values of SC hydration in healthy human adults, according to the skin area, age and sex. The databases Medline, Embase, Web of Science and Scopus were searched for primary reports, with in vivo corneometry measurements, which were conducted on disease‐free skin of human subjects, aged 18+ years in English. Risk of bias was evaluated using the critical appraisal tools for JBI Systematic Reviews, and only low‐risk studies were selected. The comparison was performed in each skin area between males and females and also between young‐ and middle‐age subjects. Among 323 Retrieved titles, full texts of 259 articles were read, and 240 studies were excluded due to unclear or insufficient reporting of SC hydration, as well as high or medium risk of bias. 19 studies (including 113 records) providing data about SC hydration in 12 skin areas were included in the final data synthesis. Pooled sample sizes ranged from n = 32 for lips to a maximum of n = 3202 for cheeks. The lowest hydration of 12.5 [95% CI 11.05–13.94] was reported for the back, and the highest hydration of 64.34) [95 CI% 62.07–64.59] for the periorbital area. Facial skin showed higher water content compared with other areas. There were also site‐dependent differences in the hydration level of the facial skin. Comparisons between two age groups, and male and female participants, did not show any statistically significant differences. The main limitation was we included studies using only one measurement device. The quality of reporting SC hydration in humans should be increased in future studies.

Tolerability and efficacy assessment of an oral collagen supplement for the improvement of biophysical and ultrasonographic parameters of skin in middle eastern consumers

Journal of Cosmetic Dermatology, Mar 13, 2023

BackgroundTopical skin care products often do not reach the deeper layers of the skin, and oral h... more BackgroundTopical skin care products often do not reach the deeper layers of the skin, and oral hydrolyzed collagen is one of the newest and most popular systemic supplementations for skin rejuvenation. However, there are limited information in case of Middle Eastern consumersObjectiveThe purpose of this study was to evaluate the tolerability and efficacy of an oral collagen supplement for improvement of skin elasticity, hydration, and roughness in Middle Eastern consumers.Methods and MaterialsIt was a 12‐week, before‐after clinical study, conducted on 20 participants (18 women and 2 men) aged 44.15 ± 5.36 years with skin type III–IV. Skin elasticity parameters (R0, R2, R5, and R7), skin hydration and friction, as well as the thickness and echo density of the dermis, were measured after six and 12 weeks daily intake of the study product, as well as 4 weeks after stopping its use (week 16). Participants' satisfaction was assessed on the basis of their answers to the standard questionnaire, and tolerability of the product was assessed by monitoring the adverse effects.ResultsA significant improvement was detected in R2, R5, and skin friction at week 12 (p‐values 0.041, 0.012 and <0.01, respectively). At week 16, the values remained at an increased level, which indicates the persistence of the results. The increase of dermis density in week 16 was also significant (p‐value = 0.03). Moderate overall satisfaction was reported with the treatment, and a few gastrointestinal complications were reported.ConclusionThe study demonstrated that oral collagen peptides could significantly improve the skin elasticity, roughness, and dermis echo density, and they also proved to be safe and well‐tolerated.

Work-a Journal of Prevention Assessment & Rehabilitation, Dec 31, 2016

BACKGROUND: Untreated Obstructive sleep apnea syndrome (OSAS) as a common breathing sleep disorde... more BACKGROUND: Untreated Obstructive sleep apnea syndrome (OSAS) as a common breathing sleep disorder results in impaired work performance. The economic burden of untreated OSAS accounts for billions of dollars per year. OBJECTIVE: The aim of this study was to evaluate the prevalence of snoring and the risk of OSAS in healthcare system staff. METHODS: This cross-sectional study was performed on 715 staff of Dr. Masih Daneshvari Hospital in 2012. The Berlin questionnaire was used to identify the prevalence of snoring and the risk of sleep apnea. Additional information, including demographic characteristics, night work, night sleep less than 4 hours, smoking, underlying disease, and quality of sleep were evaluated as well. The information was analyzed using SPSS 15. RESULTS: 12.6% reported snoring. 6.9% and 93.1% were categorized into the high and low risk groups for OSAS respectively. There was an association between the risk of OSAS and age group (P-value = 0.007), gender (P-value = 0.028), marital status (P-value = 0.008), educational level (P-value = 0.035), chronic disease (P-value = 0.008), night sleep less than 4 hours (P-value = 0.001), difficulty in staying asleep (P-value = 0.000) and waking up too early (P-value = 0.006). Even logistic regression analysis demonstrated the relationship between the risk of OSAS and night sleep less than 4 hours (P-value = 0.019) and difficulty in staying asleep (P-value = 0.009). CONCLUSIONS: The results showed that the risk of OSAS is significant in healthcare system staff. Hope to provide a special screening program for OSAS in a regular occupational examination.

Biophysical and ultrasonographic changes in early patch/plaque stage of mycosis fungoides, compared with uninvolved skin

Skin Research and Technology, May 11, 2021

BackgroundThe goal of this study was evaluation of the skin biophysical properties in early patch... more BackgroundThe goal of this study was evaluation of the skin biophysical properties in early patch/plaque stage of mycosis fungoides (MF) and its comparison with uninvolved skin in order to gain a better understanding of the pathogenesis of diseases.Materials and MethodsThe stratum corneum hydration, transepidermal water loss (TEWL), surface friction, pH, sebum, melanin, erythema, temperature, elasticity parameters (R0, R2, R5), thickness, and echo density of epidermis and dermis were measured on lesions of 21 patients and compared with controls (average measures of uninvolved perilesional and symmetrical skins) by paired sample t test.ResultsStratum corneum hydration (P < 0.001) and echo density of dermis (P = 0.044) were significantly lower, whereas pH (P‐value = 0.007), erythema (P < 0.001), and melanin content (P = 0.007) were significantly higher in lesions. There was not any significant difference in TEWL, friction index, sebum, temperature, R0, R2, R5, thickness of epidermis and dermis, and echo density of epidermis between lesions and normal skin.ConclusionParapsoriasis/MF lesions are specified by a set of certain changes in biophysical properties which are mainly correlated with histological changes. These sets of alterations may help in noninvasive, early diagnosis of parapsoriasis/MF.

Iranian Journal of Dermatology, 2017

Comparative clinical assessment of two nasolabial hyaluronic acid fillers: A double-blind, random... more Comparative clinical assessment of two nasolabial hyaluronic acid fillers: A double-blind, randomized controlled trial Background: Various fillers have been used for the correction of nasolabial folds. This study investigated the efficacy and safety assessment of two hyaluronic acid (HA) fillers on moderate nasolabial folds. Methods: This study randomized 10 volunteers, aged 35 to 49 years, with moderate nasolabial folds. Volunteers received injections of HA A and HA B gels into the right or left skin folds. The volume and surface of nasolabial folds were analyzed using CSI computer software and high frequency ultrasonography of these folds before, and 2, 12, and 24 weeks after the injection. The obtained data were analyzed using SPSS software version 20. P≤0.05 was considered significant. Results: Evaluation of the nasolabial folds before and after treatment showed significant reduction in volume of wrinkles 24 weeks after injection in both the HA gel A (-29.93±32%, P=0.022) and gel B (-23.60±26%, P=0.019). The surfaces of the wrinkles significantly decreased 24 weeks after injection of HA gel A (-29.90±31%, P=0.012) and gel B (-21.96±26%, P=0.026). Conclusion: These HA fillers provided a significant, long-lasting correction of moderate nasolabial folds. Overall, we observed no statistically significant differences in any of the measurements between the 2 gels. However, there were more observed changes made by gel A compared to gel B.

PubMed, Nov 1, 2018

Background: Contact dermatitis is a common skin condition observed by dermatologists, presenting ... more Background: Contact dermatitis is a common skin condition observed by dermatologists, presenting a burden on healthcare systems. Recently, there has been a trend in producing skin-identical topical preparations for the repair of skin. However, there is a limited number of experimental studies to assess the safety and efficacy of this products. Objective: This study assessed the clinical efficacy and safety of a skin-identical ceramide complex cream (Dermalex Repair Contact Eczema; Omega Pharma, Nazareth, Belgium) in the treatment of contact dermatitis. Design: This was a Phase II, before-after trial. Setting: This study was conducted at the Center for Research and Training in Skin Diseases and Leprosy (CRTSDL) at Tehran University of Medical Sciences in Tehran, Iran. Participants: Fifteen patients with contact dermatitis (8 men and 7 women) between the ages of 25 and 62 years (median age: 36.4 years) were enrolled in this study. Measurements: Changes were assessed using six skin biophysical parameters (transepidermal water loss [TEWL], stratum corneum [SC] hydration, melanin index, erythema index, skin pH, and skin friction), Physician Global Assessment (PGA) score, and Three-Item Severity (TIS) score at baseline, Week 2, and Week 4 of the study. Results: Skin hydration and TIS showed a statistically significant improvement after treatment with study cream (p=0.023 and p=0.007, respectively). Although the reduction in TEWL was not significant, a slight decrease was observed at Week 4. Conclusions: The skin-identical ceramide complex cream improved contact dermatitis with a decrease in TIS and an increase in skin hydration, implying a repair of the skin barrier.

Journal of Dermatology and Cosmetic, Jul 1, 2016

Conclusion: Because of no adverse changes in the skin biophysical parameters, the studied anti-de... more Conclusion: Because of no adverse changes in the skin biophysical parameters, the studied anti-dermatitis creams could be conisdered as safe products. In addition, due to selfassessment results of adverse effects by the participants, no significant adverse effect was seen.

Journal of Dermatology and Cosmetic, Jul 1, 2014

Iranian Red Crescent Medical Journal, Oct 5, 2014

Background: During the past decade, incidence of asthma has increased, which might have been due ... more Background: During the past decade, incidence of asthma has increased, which might have been due to environmental exposures. Objectives: Considering the expansion of cable manufacturing industry in Iran, the present study was conducted to evaluate the prevalence of occupational asthma in a cable manufacturing company in Iran as well as its related factors. Patients and Methods: This study was conducted on employees of a cable manufacturing company in Yazd, Iran, in 2012. The workers were divided into two groups of exposure (to toluene diisocyanate, polyvinyl chloride, polyethylene or polypropylene) and without exposure. Diagnosis of occupational asthma was made based on the subjects' medical history, spirometry and peak flowmetry, and its frequency was compared between the two groups. Results: The overall prevalence of occupational asthma was 9.7%. This rate was 13.8% in the exposed group. Logistic regression analysis showed that even after adjustment for confounding factors, a significant correlation existed between the frequency of occupational asthma and exposure to the produced dust particles (P < 0.05). In addition, age, work experience, body mass index, cigarette smoking and shift work had significant correlations with the prevalence of occupational asthma (P < 0.05). Conclusions: Considering the high prevalence of occupational asthma among cable manufacturing company workers in Iran, this issue needs to be addressed immediately in addition to reduction of exposure among subjects. Reduction in work shift duration, implementation of tobacco control and cessation programs for the personnel, and performing spirometry tests and respiratory examinations in shorter periods may be among effective measures for reducing the incidence of occupational asthma in this industry.

Assessment of the efficacy and safety of hyaluronic acid gel injection in the restoration of fullness of the upper lips

Journal of Cutaneous and Aesthetic Surgery, 2017

Lips have a significant role in face aesthetic perception, and lip augmentation is one of the mos... more Lips have a significant role in face aesthetic perception, and lip augmentation is one of the most commonly requested aesthetic procedures. Non-permanent dermal fillers, such as hyaluronic acid (HA), are used for augmenting the lips. This article presents the results of Phase II, before - after designed study, assessing the safety and efficacy of a soft tissue HA filler, for upper lip augmentation. Investigators treated 10 healthy adult women 28-45 years old, using a single injection of Hyamax Kiss soft tissue HA filler (a product from Hyamed Laboratories, Switzerland) for upper lip augmentation. The primary efficacy endpoint was an increase in lip fullness at least one grade on Medicis Lip Fullness Scale at 2, 12 and 24 weeks post-treatment. Furthermore, the effectiveness and durability of filler were assessed using a 5-point Investigator's Global Assessment (IGA). Adverse events and volunteers' satisfaction were reported using visual analog scale. Response to treatment (as defined above) after 2, 12 and 24 weeks were observed in 80%, 70% and 80% of patients, respectively. No statistical difference was found in response to treatment rate between follow-up visits ( = 0.83). The mean value of IGA score in weeks 2, 12 and 24 were 3.4 ± 0.96, 3.3 ± 0.67 and 3.3 ± 0.67, respectively. The study subjects were almost all satisfied with their lip improvement. Reported adverse effects were temporary and mostly mild in severity. Soft tissue HA filler tested in this study was well tolerated, efficient and durable when used for upper lip augmentation.

Iran Occupational Health, Oct 10, 2016

Background and aims: The use of imaging such as X-rays may have an important role in early diagno... more Background and aims: The use of imaging such as X-rays may have an important role in early diagnosis, staging, planning treatment and monitoring of patients during treatment. Radiology ward staff is at risk of low-dose occupational exposure. Therefore, this study aimed to evaluate the biological effects of low dose occupational exposure to ionizing radiation on blood cell indices of radiology ward staff employed in a governmental hospital in Tehran. Methods: In this case-control study, some blood parameters in 30 radiation workers(cases) and also 30 persons who worked in other parts of the hospital were compared. Matching was done for confounding factors. The data was analyzed with software SPSS 20 (p<0.05). Results: According to this study, there are no statistically significant differences in blood parameters such as red blood cells, white blood cells, hematocrit, platelets between radiation workers and other workers (p>0.05). Conclusion: The results of this study showed that the hematological parameters of radiation workers exposed to low doses of radiation may not predict the amount of radiation effects.

Differentiation of inflammatory papulosquamous skin diseases based on skin biophysical and ultrasonographic properties: A decision tree model

Indian Journal of Dermatology, Venereology and Leprology, 2020

Background: The biophysical and ultrasonographic properties of the skin change in papulosquamous ... more Background: The biophysical and ultrasonographic properties of the skin change in papulosquamous diseases. Aims: To identify biophysical and ultrasonographic properties for the differentiation of five main groups of papulosquamous skin diseases. Methods: Fifteen biophysical and ultrasonographic parameters were measured by multiprobe adapter system and high-frequency ultrasonography in active lesions and normal control skin in patients with chronic eczema, psoriasis, lichen planus, pityriasis rosea and parapsoriasis/mycosis fungoides. Using histological diagnosis as a gold standard, a decision tree analysis was performed based on the mean percentage changes of these parameters [(lesion–control/control) ×100] for differentiation of the diseases. Results: The accuracy of the decision tree model for differentiation of five diseases was 67% which developed based on changes in stratum corneum hydration, epidermal thickness, skin pH, melanin index, R0 (reciprocal of firmness) and erythema. Among the flowcharts for pairs of diseases, three models for differentiation had high accuracy (> 95%): those of psoriasis from lichen planus, pityriasis rosea, and parapsoriasis/mycosis fungoides. Limitations: Validation studies on a larger sample size in situations where the diagnosis is unclear are needed to confirm the accuracy and applicability of decision trees. Conclusion: Skin biophysical and ultrasonographic properties may help in the differentiation of papulosquamous diseases as simple and non-invasive tools.