M. Ferjani | University of Tunis El Manar (original) (raw)
Papers by M. Ferjani
Annales Françaises d'Anesthésie et de Réanimation, 2013
Anesthesiology Research and Practice, 2015
To prevent hypotension during spinal anesthesia for caesarean section, we assessed IV ondansetron... more To prevent hypotension during spinal anesthesia for caesarean section, we assessed IV ondansetron of invasive maternal hemodynamic and fetal gazometric parameters.
Annales de biologie clinique
The use of reliable and specific diagnosis tools in patients of intensive care unit constitutes t... more The use of reliable and specific diagnosis tools in patients of intensive care unit constitutes the best way to follow up these patients and to take charge of severe infections. It is in the context that the measuring of procalcitonin should be considered in order to prove its role in invasive candidosis. This prospective study included 52 patients from an intensive care unit. Blood samples for serum procalcitonin were drawn on days 1, 3, 5. Our results showed that on the one hand, procalcitonin levels have significantly increased in cases of confirmed and probable candidosis. On the other hand, this parameter has a certain prognosis value. In conclusion, an increase in procalcitonin level does not only imply a bacterial infection but it should also evoke a case of invasive candidosis especially in intensive care units.
Anaesthesia and intensive care, 1991
A prospective randomised study was performed to compare postoperative analgesia produced by cauda... more A prospective randomised study was performed to compare postoperative analgesia produced by caudal block with that of local wound infiltration in 54 children following unilateral inguinal herniotomy. There was no statistically significant difference in the analgesia produced by these two methods. The requirement for additional postoperative analgesia and the incidence of side-effects was similar in the two groups.
Annales Françaises d'Anesthésie et de Réanimation, 2013
versus courte (< 10 jours). Ces deux groupes ont é té comparé s sur les donné es clinicobiologiqu... more versus courte (< 10 jours). Ces deux groupes ont é té comparé s sur les donné es clinicobiologiques et les critè res suivants à j28 : mortalité ; ré cidive de bacté rié mie ; infection ou colonisation à BMR ; autres infections. Re´sultats.-Six mille sept cent soixante-quatre hé mocultures ont é té pré levé es, 572 é taient positives dont 336 à contaminants cutané s. Parmi les 236 hé mocultures positives restantes, 76 ont é té exclues (dé cè s au cours de l'antibiothé rapie, LATA ou donné es manquantes). Au total, 160 hé mocultures positives correspondant à 113 é pisodes de bacté rié mies survenus chez 94 patients ont é té é tudié es. Le dé lai de survenue mé dian de la bacté rié mie é tait de neuf jours (0-64). La majorité des hé mocultures é taient à bacilles à Gram né gatif (76 %). Les portes d'entré e é taient : 30 % primaires, 15 % infections lié es au cathé ter, 55 % lié es à un foyer infectieux
Annales Françaises d'Anesthésie et de Réanimation, 2013
Annales Françaises d Anesthésie et de Réanimation
A prospective randomised study was performed to compare postoperative analgesia produced by cauda... more A prospective randomised study was performed to compare postoperative analgesia produced by caudal block with that of local wound infiltration in 54 children following unilateral inguinal herniotomy. There was no statistically significant difference in the analgesia produced by these two methods. The requirement for additional postoperative analgesia and the incidence of side-effects was similar in the two groups.
Intensive Care Medicine Experimental, 2015
Revue du Rhumatisme, 2006
toïde (PR). Il agit en modulant sélectivement le signal de costimulation entre les récepteurs CD8... more toïde (PR). Il agit en modulant sélectivement le signal de costimulation entre les récepteurs CD80/86 et CD28 nécessaire à l'activation totale des Lymphocytes T. Son efficacité a été démontrée chez des patients ayant une PR active insuffisamment répondeurs à un anti-TNF 1 ou au MTX 2 .
Annales Françaises d Anesthésie et de Réanimation
Annales Françaises d Anesthésie et de Réanimation
Annales Françaises d Anesthésie et de Réanimation
Purpose: Aim of this study was to show the emergence of the qnr genes among fluoroquinolone-resis... more Purpose: Aim of this study was to show the emergence of the qnr genes among fluoroquinolone-resistant, AMPC and ESBL (extended-spectrum-beta-lactamase) co-producing Morganella morganii isolate. Materials and Methods: A multi resistant Morganella morganii SM12012 isolate was recovered from pus from a patient hospitalized in the intensive care unit at the Military hospital, Tunisia. Antibiotic susceptibility was tested with the agar disk diffusion method according to Clinical and Laboratory Standards Institute guidelines. ESBLs were detected using a standard double-disk synergy test. The characterization of beta-lactamases and associated resistance genes were performed by isoelectric focusing, polymerase chain reaction and nucleotide sequencing. Results: The antimicrobial susceptibility testing showed the high resistance to penicillins, cephalosporins (MICs: 64-512 μg/ml) and fluoroquinolones (MICs: 32-512 μg/ml). But M. morganii SM12012 isolate remained susceptible to carbapenems (MICs: 4-<0.25 μg/ml). The double-disk synergy test confirmed the phenotype of extendedspectrum β-lactamases (ESBLs). Three identical β-lactamases with pI values of 6.5, 7.8 and superior to 8.6 were detected after isoelectric focusing analysis. These β-lactamases genes can be successfully transferred by the conjugative plasmid. Molecular analysis demonstrated the co-production of bla
Perfusion, 2012
To evaluate the correlation and agreement between central venous saturation (ScvO(2)) and mixed v... more To evaluate the correlation and agreement between central venous saturation (ScvO(2)) and mixed venous saturation (SvO(2)) during cardiopulmonary bypass. Twenty-two consecutive patients scheduled for coronary artery surgery were prospectively included. Paired measurements of ScvO(2) and SvO(2) were performed 5 minutes after aortic cross-clamping, after each cardioplegia dose and after de-clamping of the aortic cross-clamp. ScvO(2) and SvO(2) were measured, respectively, by a fibreoptic catheter in the superior vena cava and on blood samples from the venous return line of the extracorporeal circuit, using a blood gas analyser Ninety-five paired measurements of venous saturation were obtained. Correlation between the measurements was associated with an r = 0.55. The mean bias was 2.2 [Limits of agreement: -13.6%, +18%]. Changes in oxygen saturation over time showed an r = 0.4 and a mean bias of 0.2 [Limits of agreement: -17.9%, +18.3%]. Multivariate analysis identified the oxygen cons...
Annales françaises d'anesthèsie et de rèanimation, 2007
We compared extubation time following daily interruption of sedation in intensive care unit patie... more We compared extubation time following daily interruption of sedation in intensive care unit patients with renal impairment with two sedation regimes remifentanil-midazolam and fentanyl-midazolam. Prospective, randomized double-blind trial. Patients with renal impairment needing mechanical ventilation for more than 48 hours. Two groups: remifentanil (R) and fentanyl (F), Infusion rates were titrated to achieve the desired Ramsay score. The two groups received midazolam (2.5 mg then 0.1 mg/kg/h). Nineteen patients were included. Patient's characteristics, mean sedation time and sedation quality were comparable. Extubation time was significantly shorter in R group (1480+/-980 versus 2880+/-1280 min, P=0.04). Weaning time was also shorter in R group (220+/-164 versus 720+/-480 min). Agitation on weaning was comparable in the two groups. Group R received significantly more morphine than group F after interruption of sedation. Daily interruption of sedation with remifentanil is associ...
Annales Françaises d'Anesthésie et de Réanimation, 2014
Médecine et Maladies Infectieuses, 2003
Journal of Neuroradiology, 2014
Annales Françaises d'Anesthésie et de Réanimation, 2013
Anesthesiology Research and Practice, 2015
To prevent hypotension during spinal anesthesia for caesarean section, we assessed IV ondansetron... more To prevent hypotension during spinal anesthesia for caesarean section, we assessed IV ondansetron of invasive maternal hemodynamic and fetal gazometric parameters.
Annales de biologie clinique
The use of reliable and specific diagnosis tools in patients of intensive care unit constitutes t... more The use of reliable and specific diagnosis tools in patients of intensive care unit constitutes the best way to follow up these patients and to take charge of severe infections. It is in the context that the measuring of procalcitonin should be considered in order to prove its role in invasive candidosis. This prospective study included 52 patients from an intensive care unit. Blood samples for serum procalcitonin were drawn on days 1, 3, 5. Our results showed that on the one hand, procalcitonin levels have significantly increased in cases of confirmed and probable candidosis. On the other hand, this parameter has a certain prognosis value. In conclusion, an increase in procalcitonin level does not only imply a bacterial infection but it should also evoke a case of invasive candidosis especially in intensive care units.
Anaesthesia and intensive care, 1991
A prospective randomised study was performed to compare postoperative analgesia produced by cauda... more A prospective randomised study was performed to compare postoperative analgesia produced by caudal block with that of local wound infiltration in 54 children following unilateral inguinal herniotomy. There was no statistically significant difference in the analgesia produced by these two methods. The requirement for additional postoperative analgesia and the incidence of side-effects was similar in the two groups.
Annales Françaises d'Anesthésie et de Réanimation, 2013
versus courte (< 10 jours). Ces deux groupes ont é té comparé s sur les donné es clinicobiologiqu... more versus courte (< 10 jours). Ces deux groupes ont é té comparé s sur les donné es clinicobiologiques et les critè res suivants à j28 : mortalité ; ré cidive de bacté rié mie ; infection ou colonisation à BMR ; autres infections. Re´sultats.-Six mille sept cent soixante-quatre hé mocultures ont é té pré levé es, 572 é taient positives dont 336 à contaminants cutané s. Parmi les 236 hé mocultures positives restantes, 76 ont é té exclues (dé cè s au cours de l'antibiothé rapie, LATA ou donné es manquantes). Au total, 160 hé mocultures positives correspondant à 113 é pisodes de bacté rié mies survenus chez 94 patients ont é té é tudié es. Le dé lai de survenue mé dian de la bacté rié mie é tait de neuf jours (0-64). La majorité des hé mocultures é taient à bacilles à Gram né gatif (76 %). Les portes d'entré e é taient : 30 % primaires, 15 % infections lié es au cathé ter, 55 % lié es à un foyer infectieux
Annales Françaises d'Anesthésie et de Réanimation, 2013
Annales Françaises d Anesthésie et de Réanimation
A prospective randomised study was performed to compare postoperative analgesia produced by cauda... more A prospective randomised study was performed to compare postoperative analgesia produced by caudal block with that of local wound infiltration in 54 children following unilateral inguinal herniotomy. There was no statistically significant difference in the analgesia produced by these two methods. The requirement for additional postoperative analgesia and the incidence of side-effects was similar in the two groups.
Intensive Care Medicine Experimental, 2015
Revue du Rhumatisme, 2006
toïde (PR). Il agit en modulant sélectivement le signal de costimulation entre les récepteurs CD8... more toïde (PR). Il agit en modulant sélectivement le signal de costimulation entre les récepteurs CD80/86 et CD28 nécessaire à l'activation totale des Lymphocytes T. Son efficacité a été démontrée chez des patients ayant une PR active insuffisamment répondeurs à un anti-TNF 1 ou au MTX 2 .
Annales Françaises d Anesthésie et de Réanimation
Annales Françaises d Anesthésie et de Réanimation
Annales Françaises d Anesthésie et de Réanimation
Purpose: Aim of this study was to show the emergence of the qnr genes among fluoroquinolone-resis... more Purpose: Aim of this study was to show the emergence of the qnr genes among fluoroquinolone-resistant, AMPC and ESBL (extended-spectrum-beta-lactamase) co-producing Morganella morganii isolate. Materials and Methods: A multi resistant Morganella morganii SM12012 isolate was recovered from pus from a patient hospitalized in the intensive care unit at the Military hospital, Tunisia. Antibiotic susceptibility was tested with the agar disk diffusion method according to Clinical and Laboratory Standards Institute guidelines. ESBLs were detected using a standard double-disk synergy test. The characterization of beta-lactamases and associated resistance genes were performed by isoelectric focusing, polymerase chain reaction and nucleotide sequencing. Results: The antimicrobial susceptibility testing showed the high resistance to penicillins, cephalosporins (MICs: 64-512 μg/ml) and fluoroquinolones (MICs: 32-512 μg/ml). But M. morganii SM12012 isolate remained susceptible to carbapenems (MICs: 4-<0.25 μg/ml). The double-disk synergy test confirmed the phenotype of extendedspectrum β-lactamases (ESBLs). Three identical β-lactamases with pI values of 6.5, 7.8 and superior to 8.6 were detected after isoelectric focusing analysis. These β-lactamases genes can be successfully transferred by the conjugative plasmid. Molecular analysis demonstrated the co-production of bla
Perfusion, 2012
To evaluate the correlation and agreement between central venous saturation (ScvO(2)) and mixed v... more To evaluate the correlation and agreement between central venous saturation (ScvO(2)) and mixed venous saturation (SvO(2)) during cardiopulmonary bypass. Twenty-two consecutive patients scheduled for coronary artery surgery were prospectively included. Paired measurements of ScvO(2) and SvO(2) were performed 5 minutes after aortic cross-clamping, after each cardioplegia dose and after de-clamping of the aortic cross-clamp. ScvO(2) and SvO(2) were measured, respectively, by a fibreoptic catheter in the superior vena cava and on blood samples from the venous return line of the extracorporeal circuit, using a blood gas analyser Ninety-five paired measurements of venous saturation were obtained. Correlation between the measurements was associated with an r = 0.55. The mean bias was 2.2 [Limits of agreement: -13.6%, +18%]. Changes in oxygen saturation over time showed an r = 0.4 and a mean bias of 0.2 [Limits of agreement: -17.9%, +18.3%]. Multivariate analysis identified the oxygen cons...
Annales françaises d'anesthèsie et de rèanimation, 2007
We compared extubation time following daily interruption of sedation in intensive care unit patie... more We compared extubation time following daily interruption of sedation in intensive care unit patients with renal impairment with two sedation regimes remifentanil-midazolam and fentanyl-midazolam. Prospective, randomized double-blind trial. Patients with renal impairment needing mechanical ventilation for more than 48 hours. Two groups: remifentanil (R) and fentanyl (F), Infusion rates were titrated to achieve the desired Ramsay score. The two groups received midazolam (2.5 mg then 0.1 mg/kg/h). Nineteen patients were included. Patient's characteristics, mean sedation time and sedation quality were comparable. Extubation time was significantly shorter in R group (1480+/-980 versus 2880+/-1280 min, P=0.04). Weaning time was also shorter in R group (220+/-164 versus 720+/-480 min). Agitation on weaning was comparable in the two groups. Group R received significantly more morphine than group F after interruption of sedation. Daily interruption of sedation with remifentanil is associ...
Annales Françaises d'Anesthésie et de Réanimation, 2014
Médecine et Maladies Infectieuses, 2003
Journal of Neuroradiology, 2014