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Papers by József Géza Kiss

Research paper thumbnail of Si etching affected by ir laser irradiation

Applied Physics A Solids and Surfaces, 1985

Silicon was etched in an aqueous solution of sodium hydroxide under ir laser irradiation. Two typ... more Silicon was etched in an aqueous solution of sodium hydroxide under ir laser irradiation. Two types of lasers were used, a Nd:YAG laser with a wavelength of ?=1.06 µm and a CO2 laser with ?=10.6 µm. Small-size blind holes, through holes and reliefs were formed on a Si target, and even a special type of hole can be formed with help of a CO2 laser, namely a blind hole with a hillock in its center.

Research paper thumbnail of Role of Potassium Ions and Ion Channels in the Muscle or Why is One Plate Meat Soup so Delicious?

The sensory pleasure of a good soup represents a complex synthesis of molecular and cellular inpu... more The sensory pleasure of a good soup represents a complex synthesis of molecular and cellular inputs of ions. Here we are focusing on the intake of potassium ions affecting the muscles along with the sensorineural science of eating a satisfying bowl of soup. Unbalanced ionic homeostasis and modified expression of ion channels is presumably involved in the inhibition of normal physiological functions. Salts are necessary components of soup with the flavorful broth that the salt complements turn out to activate another components of the sense of taste, the sense of savoury. Here we show the properties, molecular composition and pharmacological effects of potassium ions for the main channels of Kv-type, Kir and connexin channels in the ear system and the muscle components under physiological concentration of K-ions. However, the high concentration of K +-and Na +-ions evokes an aversive response, which is curiously not well understood at molecular level that respond to sour or bitter flavors. The ionic homeostasis has the main role to keep the cell tone in the muscle cells and, within all cells, what is supported by soup containing a wide variety of ions and flavors.

Research paper thumbnail of Cochlear implantation of a Hungarian deaf and blind patient with discharging ears suffering from Behçet's disease

The Journal of Laryngology & Otology, 1998

A case is reported in which a Nucleus 22 channel intracochlear device was implanted a deaf/blind ... more A case is reported in which a Nucleus 22 channel intracochlear device was implanted a deaf/blind Hungarian adult with discharging ears suffering from Behçet's disease. Preconditioning surgery was employed three months prior to the implantation procedure to ensure a sterile, dry protected environment for the electrodes. One month after implantation, the patient exhibited excellent auditory discrimination capability at the time of the first switch on. We suggest that some deaf/blind individuals may serve as very good candidates for intracochlear implantation.

Research paper thumbnail of Hearing disturbances in hypertrophic cardiomyopathy. Is the sensorineural disorder neurogenic or myogenic?

International Journal of Cardiology, 2007

In a previous study, we demonstrated that a hidden hearing defect is present in about 50% of pati... more In a previous study, we demonstrated that a hidden hearing defect is present in about 50% of patients with hypertrophic cardiomyopathy (HCM). Such defects were found significantly less frequently in age and clinical stage-matched patients with dilated cardiomyopathy (DCM), and were practically absent in patients with valvular aortic stenosis, and in patients taking beta-receptor blockers for different reasons (such as hypertension, ischemic heart disease, etc.). The hearing disturbances were first examined by means of brain-stem evoked response audiometry (BAEP). This method permitted only a rough differentiation between the origins of cochlear (myogenic) and retrocochlear (neurogenic) hearing disturbances, and did not allow us to establish their myogenic or neurogenic nature with certainty. Our present aim was to determine whether the hearing disturbances present in HCM and DCM patients are myogenic or neurogenic in origin. The neurogenic function of the inner ear was examined by BAEP as before, and the myogenic function by the distortion product otoacoustic emission technique. Myogenic abnormalities were found in 39/69 ears (57%) and neurogenic abnormalities in 19/69 (28%) ears among the HCM cases, as compared with 14/39 (36%) and 8/39 (21%) ears respectively among the DCM cases (p<0.005). Healthy controls displayed the lowest incidence of both types of hearing abnormalities. Our results lead us to conclude that myogenic lesions are more frequent than neurogenic lesions in patients with HCM. Both myogenic and neurogenic lesions are more frequent in HCM patients than in DCM patients or healthy controls. It may be hypothesized that abnormal sarcomeric proteins present in the muscular structures of the inner ear in HCM are possibly responsible for the hearing disorders in these patients, and that this is not merely a neurological defect.

Research paper thumbnail of The effect of Ipriflavon (Yambolap) on the otosclerotic process

Research paper thumbnail of Preferential reinnervation of adductor muscles after inferior laryengeal nerve injuries – Its clinical importance in bilateral vocal cord paresis

Introduction: Both experimental studies and clinical observations show residual adductor muscle a... more Introduction: Both experimental studies and clinical observations show residual adductor muscle activity occur very often after inferior laryngeal nerve injury. This is thought to be spontaneous regeneration of the nerve with a predominance of reinnervation of adductor muscles. This may account for [for full text, please go to the a.m. URL]

Research paper thumbnail of Computer-aided 3D visualization in oto-rhino-laryngology

Objectives: We are looking for a method to routinely evaluate CT and MR scans obtained for patien... more Objectives: We are looking for a method to routinely evaluate CT and MR scans obtained for patients who will undergo surgery. As all these data are presented to us on digital media, further possibilities open up on image processing, 3D reconstruction, and surgical planning. We were looking for free [for full text, please go to the a.m. URL]

Research paper thumbnail of Brainstem auditory evoked potential (BAEP) examinations in patients with short-standing type-1 diabetes mellitus

Introduction: Our previous results showed that diabetic neuropathy may be manifested in certain d... more Introduction: Our previous results showed that diabetic neuropathy may be manifested in certain dysfunctions of the central auditory pathways. BAEP parameters of patients with long-standing (> 20 years) type-1 diabetes mellitus differed significantly compared with healthy controls. A significant[for full text, please go to the a.m. URL]

Research paper thumbnail of Bound in bronze – a Roman bronze statuette of a barbarian prisoner

The small statuette of a bound barbarian from a Hungarian private collection is an interesting ad... more The small statuette of a bound barbarian from a Hungarian private collection is an interesting addition to the small group of these similar, although unusually harsh Roman representations of their foes. Although without a known findspot it further strengthens the previous suppositions that these were made and used for an unknown purpose at the limes, their greatest concentration being in Carnuntum.

Research paper thumbnail of Early experience on a modern, thin cochlear implant family. A retrospective, international multicenter study

Journal of Medicine and Life, 2018

Rationale: Cochlear implantation is the most effective method of rehabilitation for patients with... more Rationale: Cochlear implantation is the most effective method of rehabilitation for patients with severe to profound sensorineural hearing loss. Binaural hearing forms the basis of the development of hearing-associated cortical networks in infants and toddlers, but simultaneous bilateral implantation is often postponed due to the demands of classical surgical methods, which are associated with large incisions and a deep bony well. Objective: The authors report on the use of a modern, thin implant type and the possibilities it provided to simplify the surgical technique. Methods and results: Recent models of the Cochlear™ Nucleus® implant family were studied in an international retrospective multi-center study: 6 otolaryngologists in 5 centers shared their experiences on 73 consecutively implanted, thin implants. The surgical incision could be made shorter than before and only shallow bony wells or none at all were created in 4 out of 5 centers. No complications occurred. Discussion:...

Research paper thumbnail of Detection of “tip fold-over” of the cochlear implant electrode array with transimpedance matrix (TIM) measurement

Orvosi hetilap, 2021

Összefoglaló. Bevezetés: Az elmúlt években a cochlearis implantátum a súlyos halláskárosodás vagy... more Összefoglaló. Bevezetés: Az elmúlt években a cochlearis implantátum a súlyos halláskárosodás vagy a teljes siketség rutinszerű és hatékony kezelési eszközévé vált. Korunk egyik leggyakrabban használt és leghatékonyabb újítása a cochlearis implantációban a perimodiolaris vékony elektródasorok alkalmazása. A cochlea középtengelyét, a modiolust szorosan ölelő atraumatikus elektródasor igen meggyőző eredménnyel bizonyítja népszerűségét, mind az elektrofiziológiai mérések során, mind az akusztikus hallás megőrzése terén nyújtott teljesítményével. Ugyanakkor igen kevés publikáció írja le az elektródasor nem megfelelő helyzetének előfordulási gyakoriságát, pontosabban a visszatekeredését a csúcsi szakaszon. Célkitűzés: Tanulmányunk célja olyan szoftveres technika, a transzimpedancia-mátrix (TIM) beillesztése a rutin intraoperatív elektrofiziológiai mérési metodikák közé, amely képes objektív diagnosztikai lehetőséget biztosítani ahhoz, hogy korán felismerhessük a cochlearis implantátum ele...

Research paper thumbnail of Review of Electrode Placement with the Slim Modiolar Electrode: Identification and Management

Ideggyógyászati szemle, 2020

Az alábbi dokumentumot magáncélra töltötték le az eLitMed.hu webportálról. A dokumentum felhaszná... more Az alábbi dokumentumot magáncélra töltötték le az eLitMed.hu webportálról. A dokumentum felhasználása a szerzôi jog szabályozása alá esik.

Research paper thumbnail of Electrophysiological measurements with electrode types of different perimodiolar properties and the same cochlear implant electronics – a retrospective comparison study

Journal of Otolaryngology - Head & Neck Surgery, 2019

Research paper thumbnail of Investigation of auditory brainstem function in diabetic patients

The international tinnitus journal, 2003

We performed brainstem auditory evoked potential (BAEP) examinations in 15 patients with long-sta... more We performed brainstem auditory evoked potential (BAEP) examinations in 15 patients with long-standing type 1 diabetes mellitus. We applied cardiovascular reflex tests for assessment of autonomic neuropathy. The aim of our investigation was to compare the BAEP results of this patient group with those of controls and to look for the possible correlation between alteration of the auditory brainstem function and cardiovascular autonomic neuropathy. Analysis of the latencies (waves I, II, III, and V) and the interpeak latencies (I-III and I-V) of BAEP revealed a significant difference between those of diabetics and those of healthy controls. The amplitudes of waves I, III, and V were definitely lower in comparison with amplitudes of healthy controls. We observed a positive correlation between the overall autonomic score and the latencies (waves III and V) and interpeak latencies (I-III, I-V). These data support the hypothesis that long-standing diabetes mellitus and diabetic neuropathy ...

Research paper thumbnail of Pszichofizikai paraméterek összehasonlító elemzése a genetikai eredetű és a genetikailag nem igazolható, súlyos fokú hallássérült kisgyermekeknél, cochlearis implantációt követően

Research paper thumbnail of A Baha DermaLock implantátum rendszerrel elért audiológiai eredményeink

Research paper thumbnail of A study of central cochleovestibular function in amaurotic children

them were X-linked recessive heredity, 4 cases had normal values, and 1 case proved to have a uni... more them were X-linked recessive heredity, 4 cases had normal values, and 1 case proved to have a unilateral retrocochlear higher brainstem lesion. 4. All 4 cases with Usher's syndrom showed uni-or bilateral cochlear lesions and 2 o f them showed bilateral retrocochlear lesions too. According to our results in several types o f amaurosis the BAEP investigation have diagnostic values for a central (brainstem) affection.

Research paper thumbnail of A halláscsökkenés vinpocetin terápiája

Cél: a vinpocetin terápia halláscsökkenésben történő alkalmazásának bemutatása. Anyagok és módsze... more Cél: a vinpocetin terápia halláscsökkenésben történő alkalmazásának bemutatása. Anyagok és módszerek: A szerzők összefoglalják az akut és idiopátiás percepciós típusú halláscsökkenésben alkalmazott, általuk használt kivizsgálási és terápiás protokollt. Bemutatnak egy esettanulmányt, amelyben egy krónikusan progrediáló kétoldali percepciós típusú halláscsökkenésben szenvedő fiatalembernél érnek el szignifikáns javulást parenterális vinpocetin terápiával. Következtetés: Bizonyos percepciós típusú halláscsökkenések esetén a vinpocetin alkalmazása javulást eredményezhet

Research paper thumbnail of Megjegyzések a késő Árpád-kori pénzek jegyrendszereinek kérdéseivel kapcsolatban = Remarks on the Marking-system of the Late Árpad Age Coins

Research paper thumbnail of Comparative study of acoustically evoked brainstem potentials and vestibular findings in multiple sclerosis

Research paper thumbnail of Si etching affected by ir laser irradiation

Applied Physics A Solids and Surfaces, 1985

Silicon was etched in an aqueous solution of sodium hydroxide under ir laser irradiation. Two typ... more Silicon was etched in an aqueous solution of sodium hydroxide under ir laser irradiation. Two types of lasers were used, a Nd:YAG laser with a wavelength of ?=1.06 µm and a CO2 laser with ?=10.6 µm. Small-size blind holes, through holes and reliefs were formed on a Si target, and even a special type of hole can be formed with help of a CO2 laser, namely a blind hole with a hillock in its center.

Research paper thumbnail of Role of Potassium Ions and Ion Channels in the Muscle or Why is One Plate Meat Soup so Delicious?

The sensory pleasure of a good soup represents a complex synthesis of molecular and cellular inpu... more The sensory pleasure of a good soup represents a complex synthesis of molecular and cellular inputs of ions. Here we are focusing on the intake of potassium ions affecting the muscles along with the sensorineural science of eating a satisfying bowl of soup. Unbalanced ionic homeostasis and modified expression of ion channels is presumably involved in the inhibition of normal physiological functions. Salts are necessary components of soup with the flavorful broth that the salt complements turn out to activate another components of the sense of taste, the sense of savoury. Here we show the properties, molecular composition and pharmacological effects of potassium ions for the main channels of Kv-type, Kir and connexin channels in the ear system and the muscle components under physiological concentration of K-ions. However, the high concentration of K +-and Na +-ions evokes an aversive response, which is curiously not well understood at molecular level that respond to sour or bitter flavors. The ionic homeostasis has the main role to keep the cell tone in the muscle cells and, within all cells, what is supported by soup containing a wide variety of ions and flavors.

Research paper thumbnail of Cochlear implantation of a Hungarian deaf and blind patient with discharging ears suffering from Behçet's disease

The Journal of Laryngology & Otology, 1998

A case is reported in which a Nucleus 22 channel intracochlear device was implanted a deaf/blind ... more A case is reported in which a Nucleus 22 channel intracochlear device was implanted a deaf/blind Hungarian adult with discharging ears suffering from Behçet's disease. Preconditioning surgery was employed three months prior to the implantation procedure to ensure a sterile, dry protected environment for the electrodes. One month after implantation, the patient exhibited excellent auditory discrimination capability at the time of the first switch on. We suggest that some deaf/blind individuals may serve as very good candidates for intracochlear implantation.

Research paper thumbnail of Hearing disturbances in hypertrophic cardiomyopathy. Is the sensorineural disorder neurogenic or myogenic?

International Journal of Cardiology, 2007

In a previous study, we demonstrated that a hidden hearing defect is present in about 50% of pati... more In a previous study, we demonstrated that a hidden hearing defect is present in about 50% of patients with hypertrophic cardiomyopathy (HCM). Such defects were found significantly less frequently in age and clinical stage-matched patients with dilated cardiomyopathy (DCM), and were practically absent in patients with valvular aortic stenosis, and in patients taking beta-receptor blockers for different reasons (such as hypertension, ischemic heart disease, etc.). The hearing disturbances were first examined by means of brain-stem evoked response audiometry (BAEP). This method permitted only a rough differentiation between the origins of cochlear (myogenic) and retrocochlear (neurogenic) hearing disturbances, and did not allow us to establish their myogenic or neurogenic nature with certainty. Our present aim was to determine whether the hearing disturbances present in HCM and DCM patients are myogenic or neurogenic in origin. The neurogenic function of the inner ear was examined by BAEP as before, and the myogenic function by the distortion product otoacoustic emission technique. Myogenic abnormalities were found in 39/69 ears (57%) and neurogenic abnormalities in 19/69 (28%) ears among the HCM cases, as compared with 14/39 (36%) and 8/39 (21%) ears respectively among the DCM cases (p<0.005). Healthy controls displayed the lowest incidence of both types of hearing abnormalities. Our results lead us to conclude that myogenic lesions are more frequent than neurogenic lesions in patients with HCM. Both myogenic and neurogenic lesions are more frequent in HCM patients than in DCM patients or healthy controls. It may be hypothesized that abnormal sarcomeric proteins present in the muscular structures of the inner ear in HCM are possibly responsible for the hearing disorders in these patients, and that this is not merely a neurological defect.

Research paper thumbnail of The effect of Ipriflavon (Yambolap) on the otosclerotic process

Research paper thumbnail of Preferential reinnervation of adductor muscles after inferior laryengeal nerve injuries – Its clinical importance in bilateral vocal cord paresis

Introduction: Both experimental studies and clinical observations show residual adductor muscle a... more Introduction: Both experimental studies and clinical observations show residual adductor muscle activity occur very often after inferior laryngeal nerve injury. This is thought to be spontaneous regeneration of the nerve with a predominance of reinnervation of adductor muscles. This may account for [for full text, please go to the a.m. URL]

Research paper thumbnail of Computer-aided 3D visualization in oto-rhino-laryngology

Objectives: We are looking for a method to routinely evaluate CT and MR scans obtained for patien... more Objectives: We are looking for a method to routinely evaluate CT and MR scans obtained for patients who will undergo surgery. As all these data are presented to us on digital media, further possibilities open up on image processing, 3D reconstruction, and surgical planning. We were looking for free [for full text, please go to the a.m. URL]

Research paper thumbnail of Brainstem auditory evoked potential (BAEP) examinations in patients with short-standing type-1 diabetes mellitus

Introduction: Our previous results showed that diabetic neuropathy may be manifested in certain d... more Introduction: Our previous results showed that diabetic neuropathy may be manifested in certain dysfunctions of the central auditory pathways. BAEP parameters of patients with long-standing (> 20 years) type-1 diabetes mellitus differed significantly compared with healthy controls. A significant[for full text, please go to the a.m. URL]

Research paper thumbnail of Bound in bronze – a Roman bronze statuette of a barbarian prisoner

The small statuette of a bound barbarian from a Hungarian private collection is an interesting ad... more The small statuette of a bound barbarian from a Hungarian private collection is an interesting addition to the small group of these similar, although unusually harsh Roman representations of their foes. Although without a known findspot it further strengthens the previous suppositions that these were made and used for an unknown purpose at the limes, their greatest concentration being in Carnuntum.

Research paper thumbnail of Early experience on a modern, thin cochlear implant family. A retrospective, international multicenter study

Journal of Medicine and Life, 2018

Rationale: Cochlear implantation is the most effective method of rehabilitation for patients with... more Rationale: Cochlear implantation is the most effective method of rehabilitation for patients with severe to profound sensorineural hearing loss. Binaural hearing forms the basis of the development of hearing-associated cortical networks in infants and toddlers, but simultaneous bilateral implantation is often postponed due to the demands of classical surgical methods, which are associated with large incisions and a deep bony well. Objective: The authors report on the use of a modern, thin implant type and the possibilities it provided to simplify the surgical technique. Methods and results: Recent models of the Cochlear™ Nucleus® implant family were studied in an international retrospective multi-center study: 6 otolaryngologists in 5 centers shared their experiences on 73 consecutively implanted, thin implants. The surgical incision could be made shorter than before and only shallow bony wells or none at all were created in 4 out of 5 centers. No complications occurred. Discussion:...

Research paper thumbnail of Detection of “tip fold-over” of the cochlear implant electrode array with transimpedance matrix (TIM) measurement

Orvosi hetilap, 2021

Összefoglaló. Bevezetés: Az elmúlt években a cochlearis implantátum a súlyos halláskárosodás vagy... more Összefoglaló. Bevezetés: Az elmúlt években a cochlearis implantátum a súlyos halláskárosodás vagy a teljes siketség rutinszerű és hatékony kezelési eszközévé vált. Korunk egyik leggyakrabban használt és leghatékonyabb újítása a cochlearis implantációban a perimodiolaris vékony elektródasorok alkalmazása. A cochlea középtengelyét, a modiolust szorosan ölelő atraumatikus elektródasor igen meggyőző eredménnyel bizonyítja népszerűségét, mind az elektrofiziológiai mérések során, mind az akusztikus hallás megőrzése terén nyújtott teljesítményével. Ugyanakkor igen kevés publikáció írja le az elektródasor nem megfelelő helyzetének előfordulási gyakoriságát, pontosabban a visszatekeredését a csúcsi szakaszon. Célkitűzés: Tanulmányunk célja olyan szoftveres technika, a transzimpedancia-mátrix (TIM) beillesztése a rutin intraoperatív elektrofiziológiai mérési metodikák közé, amely képes objektív diagnosztikai lehetőséget biztosítani ahhoz, hogy korán felismerhessük a cochlearis implantátum ele...

Research paper thumbnail of Review of Electrode Placement with the Slim Modiolar Electrode: Identification and Management

Ideggyógyászati szemle, 2020

Az alábbi dokumentumot magáncélra töltötték le az eLitMed.hu webportálról. A dokumentum felhaszná... more Az alábbi dokumentumot magáncélra töltötték le az eLitMed.hu webportálról. A dokumentum felhasználása a szerzôi jog szabályozása alá esik.

Research paper thumbnail of Electrophysiological measurements with electrode types of different perimodiolar properties and the same cochlear implant electronics – a retrospective comparison study

Journal of Otolaryngology - Head & Neck Surgery, 2019

Research paper thumbnail of Investigation of auditory brainstem function in diabetic patients

The international tinnitus journal, 2003

We performed brainstem auditory evoked potential (BAEP) examinations in 15 patients with long-sta... more We performed brainstem auditory evoked potential (BAEP) examinations in 15 patients with long-standing type 1 diabetes mellitus. We applied cardiovascular reflex tests for assessment of autonomic neuropathy. The aim of our investigation was to compare the BAEP results of this patient group with those of controls and to look for the possible correlation between alteration of the auditory brainstem function and cardiovascular autonomic neuropathy. Analysis of the latencies (waves I, II, III, and V) and the interpeak latencies (I-III and I-V) of BAEP revealed a significant difference between those of diabetics and those of healthy controls. The amplitudes of waves I, III, and V were definitely lower in comparison with amplitudes of healthy controls. We observed a positive correlation between the overall autonomic score and the latencies (waves III and V) and interpeak latencies (I-III, I-V). These data support the hypothesis that long-standing diabetes mellitus and diabetic neuropathy ...

Research paper thumbnail of Pszichofizikai paraméterek összehasonlító elemzése a genetikai eredetű és a genetikailag nem igazolható, súlyos fokú hallássérült kisgyermekeknél, cochlearis implantációt követően

Research paper thumbnail of A Baha DermaLock implantátum rendszerrel elért audiológiai eredményeink

Research paper thumbnail of A study of central cochleovestibular function in amaurotic children

them were X-linked recessive heredity, 4 cases had normal values, and 1 case proved to have a uni... more them were X-linked recessive heredity, 4 cases had normal values, and 1 case proved to have a unilateral retrocochlear higher brainstem lesion. 4. All 4 cases with Usher's syndrom showed uni-or bilateral cochlear lesions and 2 o f them showed bilateral retrocochlear lesions too. According to our results in several types o f amaurosis the BAEP investigation have diagnostic values for a central (brainstem) affection.

Research paper thumbnail of A halláscsökkenés vinpocetin terápiája

Cél: a vinpocetin terápia halláscsökkenésben történő alkalmazásának bemutatása. Anyagok és módsze... more Cél: a vinpocetin terápia halláscsökkenésben történő alkalmazásának bemutatása. Anyagok és módszerek: A szerzők összefoglalják az akut és idiopátiás percepciós típusú halláscsökkenésben alkalmazott, általuk használt kivizsgálási és terápiás protokollt. Bemutatnak egy esettanulmányt, amelyben egy krónikusan progrediáló kétoldali percepciós típusú halláscsökkenésben szenvedő fiatalembernél érnek el szignifikáns javulást parenterális vinpocetin terápiával. Következtetés: Bizonyos percepciós típusú halláscsökkenések esetén a vinpocetin alkalmazása javulást eredményezhet

Research paper thumbnail of Megjegyzések a késő Árpád-kori pénzek jegyrendszereinek kérdéseivel kapcsolatban = Remarks on the Marking-system of the Late Árpad Age Coins

Research paper thumbnail of Comparative study of acoustically evoked brainstem potentials and vestibular findings in multiple sclerosis